James E Crowe

Author PubWeight™ 143.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children. N Engl J Med 2004 7.71
2 Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus. Science 2010 6.10
3 Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors. Nature 2008 3.47
4 Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes. Nat Med 2010 2.59
5 Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions. Proc Natl Acad Sci U S A 2012 2.42
6 Genetic basis for adverse events after smallpox vaccination. J Infect Dis 2008 2.09
7 The role of human metapneumovirus in upper respiratory tract infections in children: a 20-year experience. J Infect Dis 2005 2.02
8 Naturally occurring human monoclonal antibodies neutralize both 1918 and 2009 pandemic influenza A (H1N1) viruses. J Virol 2009 1.94
9 Capturing the spectrum of interaction effects in genetic association studies by simulated evaporative cooling network analysis. PLoS Genet 2009 1.91
10 A broadly neutralizing human monoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin. J Virol 2011 1.85
11 Human metapneumovirus infection in children hospitalized for wheezing. J Allergy Clin Immunol 2005 1.75
12 Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence. J Immunol 2011 1.68
13 Specificity for human hemoglobin enhances Staphylococcus aureus infection. Cell Host Microbe 2010 1.66
14 A chimeric A2 strain of respiratory syncytial virus (RSV) with the fusion protein of RSV strain line 19 exhibits enhanced viral load, mucus, and airway dysfunction. J Virol 2009 1.63
15 An optimized electrofusion-based protocol for generating virus-specific human monoclonal antibodies. J Immunol Methods 2008 1.61
16 A prospective study comparing human metapneumovirus with other respiratory viruses in adults with hematologic malignancies and respiratory tract infections. J Infect Dis 2005 1.61
17 A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin. Nat Struct Mol Biol 2013 1.60
18 Respiratory syncytial virus uses a Vps4-independent budding mechanism controlled by Rab11-FIP2. Proc Natl Acad Sci U S A 2008 1.55
19 Prospective study of the incidence, clinical features, and outcome of symptomatic upper and lower respiratory tract infections by respiratory viruses in adult recipients of hematopoietic stem cell transplants for hematologic malignancies. Biol Blood Marrow Transplant 2005 1.54
20 Persistence of circulating memory B cell clones with potential for dengue virus disease enhancement for decades following infection. J Virol 2011 1.51
21 Respiratory syncytial virus induces host RNA stress granules to facilitate viral replication. J Virol 2010 1.51
22 The cotton rat (Sigmodon hispidus) is a permissive small animal model of human metapneumovirus infection, pathogenesis, and protective immunity. J Virol 2005 1.50
23 Cooperativity of actin and microtubule elements during replication of respiratory syncytial virus. Virology 2005 1.42
24 Single molecule-sensitive probes for imaging RNA in live cells. Nat Methods 2009 1.40
25 Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes. PLoS One 2012 1.37
26 Pneumocystis carinii pneumonia in a girl with a midbrain glioma. Pediatr Hematol Oncol 2002 1.37
27 A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface. EMBO Mol Med 2014 1.37
28 Apical recycling systems regulate directional budding of respiratory syncytial virus from polarized epithelial cells. Proc Natl Acad Sci U S A 2003 1.33
29 Human metapneumovirus infection plays an etiologic role in acute asthma exacerbations requiring hospitalization in adults. J Infect Dis 2005 1.32
30 A stabilized respiratory syncytial virus reverse genetics system amenable to recombination-mediated mutagenesis. Virology 2012 1.30
31 Cytokine expression patterns associated with systemic adverse events following smallpox immunization. J Infect Dis 2006 1.29
32 Generation of recombinant human monoclonal antibodies to rotavirus from single antigen-specific B cells selected with fluorescent virus-like particles. J Immunol Methods 2003 1.27
33 Prevalence of reovirus-specific antibodies in young children in Nashville, Tennessee. J Infect Dis 2005 1.26
34 Venezuelan equine encephalitis virus replicon particles encoding respiratory syncytial virus surface glycoproteins induce protective mucosal responses in mice and cotton rats. J Virol 2007 1.24
35 Identification of an H-2D(b)-restricted CD8+ cytotoxic T lymphocyte epitope in the matrix protein of respiratory syncytial virus. Virology 2005 1.23
36 Infant and adult human B cell responses to rotavirus share common immunodominant variable gene repertoires. J Immunol 2003 1.22
37 Evidence for preferential Ig gene usage and differential TdT and exonuclease activities in human naïve and memory B cells. Mol Immunol 2006 1.22
38 Population-based incidence of human metapneumovirus infection among hospitalized children. J Infect Dis 2010 1.22
39 The potent and broadly neutralizing human dengue virus-specific monoclonal antibody 1C19 reveals a unique cross-reactive epitope on the bc loop of domain II of the envelope protein. MBio 2013 1.21
40 Adverse events after smallpox immunizations are associated with alterations in systemic cytokine levels. J Infect Dis 2004 1.21
41 Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses. J Virol 2012 1.20
42 Retracted Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific dengue immunity. Proc Natl Acad Sci U S A 2014 1.19
43 Influenza human monoclonal antibody 1F1 interacts with three major antigenic sites and residues mediating human receptor specificity in H1N1 viruses. PLoS Pathog 2012 1.19
44 Machine learning competition in immunology - Prediction of HLA class I binding peptides. J Immunol Methods 2011 1.18
45 Human monoclonal antibodies derived from memory B cells following live attenuated dengue virus vaccination or natural infection exhibit similar characteristics. J Infect Dis 2013 1.16
46 Human respiratory syncytial virus nucleoprotein and inclusion bodies antagonize the innate immune response mediated by MDA5 and MAVS. J Virol 2012 1.13
47 Differential regulation of granzyme and perforin in effector and memory T cells following smallpox immunization. J Immunol 2005 1.12
48 Antibody recognition of the pandemic H1N1 Influenza virus hemagglutinin receptor binding site. J Virol 2013 1.12
49 Vaccination success rate and reaction profile with diluted and undiluted smallpox vaccine: a randomized controlled trial. JAMA 2004 1.11
50 An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody. MBio 2011 1.11
51 Amphiregulin-deficient mice develop spasmolytic polypeptide expressing metaplasia and intestinal metaplasia. Gastroenterology 2008 1.11
52 Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site. Nat Struct Mol Biol 2012 1.11
53 Human metapneumovirus fusion protein vaccines that are immunogenic and protective in cotton rats. J Virol 2006 1.10
54 Identification of a novel human leucocyte antigen-A*01-restricted cytotoxic T-lymphocyte epitope in the respiratory syncytial virus fusion protein. Immunology 2003 1.09
55 Functional maturation of the human antibody response to rotavirus. J Immunol 2008 1.09
56 VH1-46 is the dominant immunoglobulin heavy chain gene segment in rotavirus-specific memory B cells expressing the intestinal homing receptor alpha4beta7. J Immunol 2005 1.08
57 Coronavirus infection and hospitalizations for acute respiratory illness in young children. J Med Virol 2009 1.08
58 The transmembrane domain of the respiratory syncytial virus F protein is an orientation-independent apical plasma membrane sorting sequence. J Virol 2005 1.08
59 A critical phenylalanine residue in the respiratory syncytial virus fusion protein cytoplasmic tail mediates assembly of internal viral proteins into viral filaments and particles. MBio 2012 1.07
60 Immunodominance of the VH1-46 antibody gene segment in the primary repertoire of human rotavirus-specific B cells is reduced in the memory compartment through somatic mutation of nondominant clones. J Immunol 2008 1.06
61 Frequency and genetic characterization of V(DD)J recombinants in the human peripheral blood antibody repertoire. Immunology 2012 1.05
62 Genetic diversity and evolution of human metapneumovirus fusion protein over twenty years. Virol J 2009 1.04
63 Cellular immune responses to diluted and undiluted aventis pasteur smallpox vaccine. J Infect Dis 2006 1.04
64 Respiratory syncytial virus nucleoprotein-specific cytotoxic T-cell epitopes in a South African population of diverse HLA types are conserved in circulating field strains. J Virol 2003 1.03
65 The pediatric burden of human coronaviruses evaluated for twenty years. Pediatr Infect Dis J 2009 1.02
66 A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutically in vivo. J Virol 2007 1.02
67 Activation of protein kinase R is required for induction of stress granules by respiratory syncytial virus but dispensable for viral replication. Virology 2011 1.02
68 Progression of respiratory syncytial virus infection monitored by fluorescent quantum dot probes. Nano Lett 2005 1.02
69 Pseudovirion particles bearing native HIV envelope trimers facilitate a novel method for generating human neutralizing monoclonal antibodies against HIV. J Acquir Immune Defic Syndr 2010 1.00
70 Discovering naturally processed antigenic determinants that confer protective T cell immunity. J Clin Invest 2013 0.99
71 Maturation-induced cloaking of neutralization epitopes on HIV-1 particles. PLoS Pathog 2011 0.99
72 Independent structural domains in paramyxovirus polymerase protein. J Biol Chem 2012 0.98
73 Natural evolution of a human virus-specific antibody gene repertoire by somatic hypermutation requires both hotspot-directed and randomly-directed processes. Hum Immunol 2005 0.98
74 An alphavirus replicon-based human metapneumovirus vaccine is immunogenic and protective in mice and cotton rats. J Virol 2008 0.98
75 Human rotavirus VP6-specific antibodies mediate intracellular neutralization by binding to a quaternary structure in the transcriptional pore. PLoS One 2013 0.98
76 Tissue-specific regulation of CD8+ T-lymphocyte immunodominance in respiratory syncytial virus infection. J Virol 2006 0.97
77 Using the natural evolution of a rotavirus-specific human monoclonal antibody to predict the complex topography of a viral antigenic site. Immunome Res 2007 0.96
78 Effect of zinc salts on respiratory syncytial virus replication. Antimicrob Agents Chemother 2004 0.94
79 Examination of a fusogenic hexameric core from human metapneumovirus and identification of a potent synthetic peptide inhibitor from the heptad repeat 1 region. J Virol 2006 0.94
80 Respiratory syncytial virus regulates human microRNAs by using mechanisms involving beta interferon and NF-κB. MBio 2012 0.93
81 Transforming growth factor beta is a major regulator of human neonatal immune responses following respiratory syncytial virus infection. J Virol 2010 0.92
82 Tissue-specific regulatory T cells: biomarker for acute graft-vs-host disease and survival. Exp Hematol 2012 0.92
83 Impact of new sequencing technologies on studies of the human B cell repertoire. Curr Opin Immunol 2013 0.92
84 Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses. J Clin Invest 2013 0.92
85 The human polymeric immunoglobulin receptor facilitates invasion of epithelial cells by Streptococcus pneumoniae in a strain-specific and cell type-specific manner. Infect Immun 2002 0.90
86 Human germline antibody gene segments encode polyspecific antibodies. PLoS Comput Biol 2013 0.89
87 Prophylactic and therapeutic testing of Nicotiana-derived RSV-neutralizing human monoclonal antibodies in the cotton rat model. MAbs 2013 0.89
88 Identification of potential human respiratory syncytial virus and metapneumovirus T cell epitopes using computational prediction and MHC binding assays. J Immunol Methods 2011 0.89
89 Human metapneumovirus nucleoprotein and phosphoprotein interact and provide the minimal requirements for inclusion body formation. J Gen Virol 2008 0.89
90 Combining single RNA sensitive probes with subdiffraction-limited and live-cell imaging enables the characterization of virus dynamics in cells. ACS Nano 2013 0.87
91 Respiratory syncytial virus assembles into structured filamentous virion particles independently of host cytoskeleton and related proteins. PLoS One 2012 0.87
92 Reversion of somatic mutations of the respiratory syncytial virus-specific human monoclonal antibody Fab19 reveal a direct relationship between association rate and neutralizing potency. J Immunol 2013 0.86
93 Genetic predisposition for adverse events after vaccination. J Infect Dis 2007 0.86
94 The human neonatal B cell response to respiratory syncytial virus uses a biased antibody variable gene repertoire that lacks somatic mutations. Mol Immunol 2009 0.86
95 Sagittal orientation of ingested coins in the esophagus in children. AJR Am J Roentgenol 2011 0.85
96 Use of Human Hybridoma Technology To Isolate Human Monoclonal Antibodies. Microbiol Spectr 2015 0.85
97 Predicting posttransplantation diabetes mellitus by regulatory T-cell phenotype: implications for metabolic intervention to modulate alloreactivity. Blood 2012 0.85
98 Rotavirus-specific CD5+ B cells in young children exhibit a distinct antibody repertoire compared with CD5- B cells. Hum Immunol 2006 0.84
99 Enhancement of the CD8+ T cell response to a subdominant epitope of respiratory syncytial virus by deletion of an immunodominant epitope. Vaccine 2008 0.84
100 Pseudovirion particle production by live poxvirus human immunodeficiency virus vaccine vector enhances humoral and cellular immune responses. J Virol 2005 0.84
101 Low expression of the interleukin (IL)-4 receptor alpha chain and reduced signalling via the IL-4 receptor complex in human neonatal B cells. Immunology 2006 0.83
102 Gold nanorod vaccine for respiratory syncytial virus. Nanotechnology 2013 0.83
103 Unusual features of vaccinia virus extracellular virion form neutralization resistance revealed in human antibody responses to the smallpox vaccine. J Virol 2012 0.82
104 Homing in on acute graft vs. host disease: tissue-specific T regulatory and Th17 cells. Curr Top Microbiol Immunol 2010 0.81
105 Fatal hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus infection in a patient with a novel mutation in the signaling lymphocytic activation molecule-associated protein. Clin Infect Dis 2003 0.81
106 Emerging studies of human HIV-specific antibody repertoires. Vaccine 2010 0.81
107 Smallpox vaccination does not elevate systemic levels of prothrombotic proteins associated with ischemic cardiac events. J Infect Dis 2005 0.81
108 Transcriptional control of activation-induced cytidine deaminase and error-prone DNA polymerases is functionally mature in the B cells of infants at birth. Hum Immunol 2006 0.80
109 A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase. Chembiochem 2012 0.80
110 Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth. J Clin Invest 2015 0.79
111 Differential accessibility of a rotavirus VP6 epitope in trimers comprising type I, II, or III channels as revealed by binding of a human rotavirus VP6-specific antibody. J Virol 2013 0.78
112 Intermittent testicular torsion in the pediatric patient: sonographic indicators of a difficult diagnosis. AJR Am J Roentgenol 2013 0.78
113 Molecular mechanisms driving respiratory syncytial virus assembly. Future Microbiol 2013 0.77
114 Monoclonal antibodies against the Staphylococcus aureus bicomponent leukotoxin AB (LukAB) isolated following invasive human infection reveal diverse binding and modes of action. J Infect Dis 2017 0.76
115 H7N9 influenza virus neutralizing antibodies that possess few somatic mutations. J Clin Invest 2016 0.76
116 Broadly neutralizing antibodies with few somatic mutations and hepatitis C virus clearance. JCI Insight 2017 0.75
117 Intracellular neutralization of a virus using a cell-penetrating molecular transporter. Nanomedicine (Lond) 2013 0.75
118 Committing the Oldest Sins in the Newest Kind of Ways-Antibodies Targeting the Influenza Virus Type A Hemagglutinin Globular Head. Microbiol Spectr 2014 0.75