Published in Antimicrob Agents Chemother on March 01, 2004
Zinc acetate/carrageenan gels exhibit potent activity in vivo against high-dose herpes simplex virus 2 vaginal and rectal challenge. Antimicrob Agents Chemother (2011) 1.23
Molecular characterization of transcriptome-wide interactions between highly pathogenic porcine reproductive and respiratory syndrome virus and porcine alveolar macrophages in vivo. Int J Biol Sci (2011) 1.06
Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture. PLoS Pathog (2010) 0.99
Efficacy and toxicity of zinc salts as candidate topical microbicides against vaginal herpes simplex virus type 2 infection. Antimicrob Agents Chemother (2005) 0.97
A modified zinc acetate gel, a potential nonantiretroviral microbicide, is safe and effective against simian-human immunodeficiency virus and herpes simplex virus 2 infection in vivo. Antimicrob Agents Chemother (2013) 0.95
Zinc for the treatment of the common cold: a systematic review and meta-analysis of randomized controlled trials. CMAJ (2012) 0.92
Treating cough and cold: Guidance for caregivers of children and youth. Paediatr Child Health (2011) 0.89
Non-specific microbicide product development: then and now. Curr HIV Res (2012) 0.85
High-dose dietary zinc oxide mitigates infection with transmissible gastroenteritis virus in piglets. BMC Vet Res (2014) 0.76
Protective hybrid coating containing silver, copper and zinc cations effective against human immunodeficiency virus and other enveloped viruses. BMC Microbiol (2016) 0.75
Zinc salts block Hepatitis E virus replication by inhibiting the activity of viral RNA-dependent RNA polymerase. J Virol (2017) 0.75
Risk of primary infection and reinfection with respiratory syncytial virus. Am J Dis Child (1986) 7.39
Zinc gluconate lozenges for treating the common cold. A randomized, double-blind, placebo-controlled study. Ann Intern Med (1996) 5.77
Prevention of diarrhea and pneumonia by zinc supplementation in children in developing countries: pooled analysis of randomized controlled trials. Zinc Investigators' Collaborative Group. J Pediatr (1999) 4.57
Zinc and immune function: the biological basis of altered resistance to infection. Am J Clin Nutr (1998) 4.23
Risk of respiratory syncytial virus infection for infants from low-income families in relationship to age, sex, ethnic group, and maternal antibody level. J Pediatr (1981) 4.00
Respiratory syncytial virus infection in tropical and developing countries. Trop Med Int Health (1998) 3.38
Duration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. A randomized, double-blind, placebo-controlled trial. Ann Intern Med (2000) 3.23
Zinc ions inhibit replication of rhinoviruses. Nature (1974) 2.92
Reduction in duration of common colds by zinc gluconate lozenges in a double-blind study. Antimicrob Agents Chemother (1984) 2.40
Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial. Pediatrics (1998) 1.95
Inhibition by zinc of rhinovirus protein cleavage: interaction of zinc with capsid polypeptides. J Virol (1976) 1.71
Potential interventions for the prevention of childhood pneumonia in developing countries: improving nutrition. Am J Clin Nutr (1999) 1.57
Twenty years of outpatient respiratory syncytial virus infection: a framework for vaccine efficacy trials. Pediatrics (1997) 1.51
Etiology of serious infections in young Gambian infants. Pediatr Infect Dis J (1999) 1.42
In vitro activity of zinc salts against human rhinoviruses. Antimicrob Agents Chemother (1987) 1.40
Changes in cytokine production and T cell subpopulations in experimentally induced zinc-deficient humans. Am J Physiol (1997) 1.39
Zinc and infection. Rev Infect Dis (1983) 1.30
Zinc deficiency and immune function. Annu Rev Nutr (1990) 1.24
Zinc gluconate lozenges for common cold. A double-blind clinical trial. Dan Med Bull (1990) 1.12
Zinc salts inactivate clinical isolates of herpes simplex virus in vitro. J Clin Microbiol (2000) 1.10
Inhibition of HIV-1 infection by zinc group metal compounds. Antiviral Res (1999) 1.09
Topical application of zinc-solutions: a new treatment for herpes simplex infections of the skin? Acta Derm Venereol (1980) 1.04
The mechanism of the antiherpetic activity of zinc sulphate. J Gen Virol (1990) 1.01
Inhibition of vaccinia virus maturation by zinc chloride. Antimicrob Agents Chemother (1981) 1.00
Failure of zinc gluconate in treatment of acute upper respiratory tract infections. Antimicrob Agents Chemother (1989) 0.97
Controlled trial of zinc supplementation during recovery from malnutrition: effects on growth and immune function. Am J Clin Nutr (1987) 0.94
Uptake and toxic effects of heavy metal ions: interactions among cadmium, copper and zinc in cultured cells. Experientia (1987) 0.80
Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children. N Engl J Med (2004) 7.71
Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus. Science (2010) 6.10
Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors. Nature (2008) 3.47
Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes. Nat Med (2010) 2.59
Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions. Proc Natl Acad Sci U S A (2012) 2.42
Genetic basis for adverse events after smallpox vaccination. J Infect Dis (2008) 2.09
The role of human metapneumovirus in upper respiratory tract infections in children: a 20-year experience. J Infect Dis (2005) 2.02
Naturally occurring human monoclonal antibodies neutralize both 1918 and 2009 pandemic influenza A (H1N1) viruses. J Virol (2009) 1.94
Capturing the spectrum of interaction effects in genetic association studies by simulated evaporative cooling network analysis. PLoS Genet (2009) 1.91
A broadly neutralizing human monoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin. J Virol (2011) 1.85
Human metapneumovirus infection in children hospitalized for wheezing. J Allergy Clin Immunol (2005) 1.75
Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence. J Immunol (2011) 1.68
Specificity for human hemoglobin enhances Staphylococcus aureus infection. Cell Host Microbe (2010) 1.66
A chimeric A2 strain of respiratory syncytial virus (RSV) with the fusion protein of RSV strain line 19 exhibits enhanced viral load, mucus, and airway dysfunction. J Virol (2009) 1.63
An optimized electrofusion-based protocol for generating virus-specific human monoclonal antibodies. J Immunol Methods (2008) 1.61
A prospective study comparing human metapneumovirus with other respiratory viruses in adults with hematologic malignancies and respiratory tract infections. J Infect Dis (2005) 1.61
A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin. Nat Struct Mol Biol (2013) 1.60
Respiratory syncytial virus uses a Vps4-independent budding mechanism controlled by Rab11-FIP2. Proc Natl Acad Sci U S A (2008) 1.55
Prospective study of the incidence, clinical features, and outcome of symptomatic upper and lower respiratory tract infections by respiratory viruses in adult recipients of hematopoietic stem cell transplants for hematologic malignancies. Biol Blood Marrow Transplant (2005) 1.54
Persistence of circulating memory B cell clones with potential for dengue virus disease enhancement for decades following infection. J Virol (2011) 1.51
Respiratory syncytial virus induces host RNA stress granules to facilitate viral replication. J Virol (2010) 1.51
The cotton rat (Sigmodon hispidus) is a permissive small animal model of human metapneumovirus infection, pathogenesis, and protective immunity. J Virol (2005) 1.50
Cooperativity of actin and microtubule elements during replication of respiratory syncytial virus. Virology (2005) 1.42
Single molecule-sensitive probes for imaging RNA in live cells. Nat Methods (2009) 1.40
Pneumocystis carinii pneumonia in a girl with a midbrain glioma. Pediatr Hematol Oncol (2002) 1.37
Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes. PLoS One (2012) 1.37
A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface. EMBO Mol Med (2014) 1.37
Apical recycling systems regulate directional budding of respiratory syncytial virus from polarized epithelial cells. Proc Natl Acad Sci U S A (2003) 1.33
Human metapneumovirus infection plays an etiologic role in acute asthma exacerbations requiring hospitalization in adults. J Infect Dis (2005) 1.32
A stabilized respiratory syncytial virus reverse genetics system amenable to recombination-mediated mutagenesis. Virology (2012) 1.30
Cytokine expression patterns associated with systemic adverse events following smallpox immunization. J Infect Dis (2006) 1.29
Generation of recombinant human monoclonal antibodies to rotavirus from single antigen-specific B cells selected with fluorescent virus-like particles. J Immunol Methods (2003) 1.27
Prevalence of reovirus-specific antibodies in young children in Nashville, Tennessee. J Infect Dis (2005) 1.26
Venezuelan equine encephalitis virus replicon particles encoding respiratory syncytial virus surface glycoproteins induce protective mucosal responses in mice and cotton rats. J Virol (2007) 1.24
Identification of an H-2D(b)-restricted CD8+ cytotoxic T lymphocyte epitope in the matrix protein of respiratory syncytial virus. Virology (2005) 1.23
Evidence for preferential Ig gene usage and differential TdT and exonuclease activities in human naïve and memory B cells. Mol Immunol (2006) 1.22
Infant and adult human B cell responses to rotavirus share common immunodominant variable gene repertoires. J Immunol (2003) 1.22
Population-based incidence of human metapneumovirus infection among hospitalized children. J Infect Dis (2010) 1.22
Adverse events after smallpox immunizations are associated with alterations in systemic cytokine levels. J Infect Dis (2004) 1.21
Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses. J Virol (2012) 1.20
Retracted Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific dengue immunity. Proc Natl Acad Sci U S A (2014) 1.19
Influenza human monoclonal antibody 1F1 interacts with three major antigenic sites and residues mediating human receptor specificity in H1N1 viruses. PLoS Pathog (2012) 1.19
Machine learning competition in immunology - Prediction of HLA class I binding peptides. J Immunol Methods (2011) 1.18
Human monoclonal antibodies derived from memory B cells following live attenuated dengue virus vaccination or natural infection exhibit similar characteristics. J Infect Dis (2013) 1.16
Human respiratory syncytial virus nucleoprotein and inclusion bodies antagonize the innate immune response mediated by MDA5 and MAVS. J Virol (2012) 1.13
Differential regulation of granzyme and perforin in effector and memory T cells following smallpox immunization. J Immunol (2005) 1.12
Antibody recognition of the pandemic H1N1 Influenza virus hemagglutinin receptor binding site. J Virol (2013) 1.12
Vaccination success rate and reaction profile with diluted and undiluted smallpox vaccine: a randomized controlled trial. JAMA (2004) 1.11
An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody. MBio (2011) 1.11
Amphiregulin-deficient mice develop spasmolytic polypeptide expressing metaplasia and intestinal metaplasia. Gastroenterology (2008) 1.11
Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site. Nat Struct Mol Biol (2012) 1.11
Human metapneumovirus fusion protein vaccines that are immunogenic and protective in cotton rats. J Virol (2006) 1.10
Identification of a novel human leucocyte antigen-A*01-restricted cytotoxic T-lymphocyte epitope in the respiratory syncytial virus fusion protein. Immunology (2003) 1.09
Functional maturation of the human antibody response to rotavirus. J Immunol (2008) 1.09
VH1-46 is the dominant immunoglobulin heavy chain gene segment in rotavirus-specific memory B cells expressing the intestinal homing receptor alpha4beta7. J Immunol (2005) 1.08
The transmembrane domain of the respiratory syncytial virus F protein is an orientation-independent apical plasma membrane sorting sequence. J Virol (2005) 1.08
Coronavirus infection and hospitalizations for acute respiratory illness in young children. J Med Virol (2009) 1.08
Immunodominance of the VH1-46 antibody gene segment in the primary repertoire of human rotavirus-specific B cells is reduced in the memory compartment through somatic mutation of nondominant clones. J Immunol (2008) 1.06
Frequency and genetic characterization of V(DD)J recombinants in the human peripheral blood antibody repertoire. Immunology (2012) 1.05
Genetic diversity and evolution of human metapneumovirus fusion protein over twenty years. Virol J (2009) 1.04
Cellular immune responses to diluted and undiluted aventis pasteur smallpox vaccine. J Infect Dis (2006) 1.04
Respiratory syncytial virus nucleoprotein-specific cytotoxic T-cell epitopes in a South African population of diverse HLA types are conserved in circulating field strains. J Virol (2003) 1.03
The pediatric burden of human coronaviruses evaluated for twenty years. Pediatr Infect Dis J (2009) 1.02
A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutically in vivo. J Virol (2007) 1.02
Activation of protein kinase R is required for induction of stress granules by respiratory syncytial virus but dispensable for viral replication. Virology (2011) 1.02
Progression of respiratory syncytial virus infection monitored by fluorescent quantum dot probes. Nano Lett (2005) 1.02
Pseudovirion particles bearing native HIV envelope trimers facilitate a novel method for generating human neutralizing monoclonal antibodies against HIV. J Acquir Immune Defic Syndr (2010) 1.00
Discovering naturally processed antigenic determinants that confer protective T cell immunity. J Clin Invest (2013) 0.99
Maturation-induced cloaking of neutralization epitopes on HIV-1 particles. PLoS Pathog (2011) 0.99
Natural evolution of a human virus-specific antibody gene repertoire by somatic hypermutation requires both hotspot-directed and randomly-directed processes. Hum Immunol (2005) 0.98
Independent structural domains in paramyxovirus polymerase protein. J Biol Chem (2012) 0.98
An alphavirus replicon-based human metapneumovirus vaccine is immunogenic and protective in mice and cotton rats. J Virol (2008) 0.98
Human rotavirus VP6-specific antibodies mediate intracellular neutralization by binding to a quaternary structure in the transcriptional pore. PLoS One (2013) 0.98
Tissue-specific regulation of CD8+ T-lymphocyte immunodominance in respiratory syncytial virus infection. J Virol (2006) 0.97
Using the natural evolution of a rotavirus-specific human monoclonal antibody to predict the complex topography of a viral antigenic site. Immunome Res (2007) 0.96
Examination of a fusogenic hexameric core from human metapneumovirus and identification of a potent synthetic peptide inhibitor from the heptad repeat 1 region. J Virol (2006) 0.94
Respiratory syncytial virus regulates human microRNAs by using mechanisms involving beta interferon and NF-κB. MBio (2012) 0.93
Transforming growth factor beta is a major regulator of human neonatal immune responses following respiratory syncytial virus infection. J Virol (2010) 0.92
Impact of new sequencing technologies on studies of the human B cell repertoire. Curr Opin Immunol (2013) 0.92
Tissue-specific regulatory T cells: biomarker for acute graft-vs-host disease and survival. Exp Hematol (2012) 0.92
Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses. J Clin Invest (2013) 0.92
The human polymeric immunoglobulin receptor facilitates invasion of epithelial cells by Streptococcus pneumoniae in a strain-specific and cell type-specific manner. Infect Immun (2002) 0.90
Prophylactic and therapeutic testing of Nicotiana-derived RSV-neutralizing human monoclonal antibodies in the cotton rat model. MAbs (2013) 0.89
Human germline antibody gene segments encode polyspecific antibodies. PLoS Comput Biol (2013) 0.89
Human metapneumovirus nucleoprotein and phosphoprotein interact and provide the minimal requirements for inclusion body formation. J Gen Virol (2008) 0.89
Identification of potential human respiratory syncytial virus and metapneumovirus T cell epitopes using computational prediction and MHC binding assays. J Immunol Methods (2011) 0.89
Combining single RNA sensitive probes with subdiffraction-limited and live-cell imaging enables the characterization of virus dynamics in cells. ACS Nano (2013) 0.87
Respiratory syncytial virus assembles into structured filamentous virion particles independently of host cytoskeleton and related proteins. PLoS One (2012) 0.87
The human neonatal B cell response to respiratory syncytial virus uses a biased antibody variable gene repertoire that lacks somatic mutations. Mol Immunol (2009) 0.86
Reversion of somatic mutations of the respiratory syncytial virus-specific human monoclonal antibody Fab19 reveal a direct relationship between association rate and neutralizing potency. J Immunol (2013) 0.86
Genetic predisposition for adverse events after vaccination. J Infect Dis (2007) 0.86
Sagittal orientation of ingested coins in the esophagus in children. AJR Am J Roentgenol (2011) 0.85
Use of Human Hybridoma Technology To Isolate Human Monoclonal Antibodies. Microbiol Spectr (2015) 0.85
Predicting posttransplantation diabetes mellitus by regulatory T-cell phenotype: implications for metabolic intervention to modulate alloreactivity. Blood (2012) 0.85
Rotavirus-specific CD5+ B cells in young children exhibit a distinct antibody repertoire compared with CD5- B cells. Hum Immunol (2006) 0.84
Enhancement of the CD8+ T cell response to a subdominant epitope of respiratory syncytial virus by deletion of an immunodominant epitope. Vaccine (2008) 0.84
Pseudovirion particle production by live poxvirus human immunodeficiency virus vaccine vector enhances humoral and cellular immune responses. J Virol (2005) 0.84
Low expression of the interleukin (IL)-4 receptor alpha chain and reduced signalling via the IL-4 receptor complex in human neonatal B cells. Immunology (2006) 0.83