Published in J Am Acad Dermatol on March 01, 2005
Mechanisms of cellular uptake of cell-penetrating peptides. J Biophys (2011) 2.34
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Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers. J Invest Dermatol (2007) 2.02
The skin barrier as an innate immune element. Semin Immunopathol (2007) 1.81
Inhibition of influenza virus infection by a novel antiviral peptide that targets viral attachment to cells. J Virol (2006) 1.54
Antimicrobial peptides: natural effectors of the innate immune system. Semin Immunopathol (2007) 1.43
Bacterial persister cell formation and dormancy. Appl Environ Microbiol (2013) 1.28
Histone H4 is a major component of the antimicrobial action of human sebocytes. J Invest Dermatol (2009) 1.03
Pattern of mRNA expression of beta-defensins in basal cell carcinoma. BMC Cancer (2006) 0.96
Filming biomolecular processes by high-speed atomic force microscopy. Chem Rev (2014) 0.95
Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa. J Biol Chem (2013) 0.95
The host defense peptide beta-defensin 1 confers protection against Bordetella pertussis in newborn piglets. Infect Immun (2006) 0.89
Antimicrobial resistance in Acinetobacter baumannii: From bench to bedside. World J Clin Cases (2014) 0.88
Yersinia pestis AcrAB-TolC in antibiotic resistance and virulence. Antimicrob Agents Chemother (2011) 0.86
Eurocin, a new fungal defensin: structure, lipid binding, and its mode of action. J Biol Chem (2012) 0.86
Antimicrobial activities of chemokines: not just a side-effect? Front Immunol (2012) 0.86
Development of a novel antimicrobial peptide, AG-30, with angiogenic properties. J Cell Mol Med (2008) 0.84
Cationic antimicrobial peptide LL-37 is effective against both extra- and intracellular Staphylococcus aureus. Antimicrob Agents Chemother (2012) 0.83
Design, recombinant expression, and antibacterial activity of the cecropins-melittin hybrid antimicrobial peptides. Curr Microbiol (2010) 0.83
Bacterial Evasion of Host Antimicrobial Peptide Defenses. Microbiol Spectr (2016) 0.82
Antimicrobial metallopeptides with broad nuclease and ribonuclease activity. Chem Commun (Camb) (2013) 0.81
Topical antimicrobials for burn infections - an update. Recent Pat Antiinfect Drug Discov (2013) 0.80
NKLP27: a teleost NK-lysin peptide that modulates immune response, induces degradation of bacterial DNA, and inhibits bacterial and viral infection. PLoS One (2014) 0.80
Antimicrobial activity and molecular mechanism of the CRES protein. PLoS One (2012) 0.79
Utility of ⁹⁹mTc-labelled antimicrobial peptide ubiquicidin (29-41) in the diagnosis of diabetic foot infection. Eur J Nucl Med Mol Imaging (2013) 0.79
The crude skin secretion of the pepper frog Leptodactylus labyrinthicus is rich in metallo and serine peptidases. PLoS One (2014) 0.78
Interaction of the antimicrobial peptide polymyxin B1 with both membranes of E. coli: a molecular dynamics study. PLoS Comput Biol (2015) 0.77
Synthesis and characterization of the 47-residue heterodimeric antimicrobial peptide distinctin, featuring directed disulfide bridge formation. Biopolymers (2012) 0.77
On the role of NMR spectroscopy for characterization of antimicrobial peptides. Methods Mol Biol (2013) 0.77
Synthesis of a New Peptide-Coumarin Conjugate: A Potential Agent against Cryptococcosis. ACS Med Chem Lett (2015) 0.76
Controlling Persister and Biofilm Cells of Gram-Negative Bacteria with a New 1,3,5-Triazine Derivative. Pharmaceuticals (Basel) (2015) 0.75
CXCL14 as an emerging immune and inflammatory modulator. J Inflamm (Lond) (2016) 0.75
Heterologous expression of abaecin peptide from Apis mellifera in Pichia pastoris. Microb Cell Fact (2017) 0.75
Beta-Defensin 124 Is Required for Efficient Innate Immune Responses in Prostate Epithelial RWPE-1 Cells. Korean J Urol (2014) 0.75
Rapid Screening of Antimicrobial Synthetic Peptides. Int J Pept Res Ther (2015) 0.75
Scaffold-based anti-infection strategies in bone repair. Ann Biomed Eng (2014) 0.75
Elevated Concentration of Defensins in Hepatitis C Virus-Infected Patients. J Immunol Res (2016) 0.75
Amyloidogenic amyloid-β-peptide variants induce microbial agglutination and exert antimicrobial activity. Sci Rep (2016) 0.75
Findings on the interaction of the antimicrobial peptide cecropin-melittin with a gold surface from molecular dynamics studies. Eur Biophys J (2016) 0.75
Antibacterial Activity of AI-Hemocidin 2, a Novel N-Terminal Peptide of Hemoglobin Purified from Arca inflata. Mar Drugs (2017) 0.75
Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science (2006) 18.74
The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab (2010) 13.29
Endogenous antimicrobial peptides and skin infections in atopic dermatitis. N Engl J Med (2002) 9.01
The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection. Nat Med (2006) 5.20
Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism. J Clin Invest (2007) 3.82
HIF-1alpha expression regulates the bactericidal capacity of phagocytes. J Clin Invest (2005) 3.77
Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea. Nat Med (2007) 3.75
AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense. Trends Immunol (2009) 3.40
Cytokine milieu of atopic dermatitis skin subverts the innate immune response to vaccinia virus. Immunity (2006) 3.39
Commensal bacteria regulate Toll-like receptor 3-dependent inflammation after skin injury. Nat Med (2009) 3.32
An angiogenic role for the human peptide antibiotic LL-37/hCAP-18. J Clin Invest (2003) 3.19
Recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on Toll-like receptor 4, CD44, and MD-2. J Biol Chem (2007) 2.82
Hyaluronan fragments stimulate endothelial recognition of injury through TLR4. J Biol Chem (2004) 2.81
IOM committee members respond to Endocrine Society vitamin D guideline. J Clin Endocrinol Metab (2012) 2.75
Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3. J Invest Dermatol (2007) 2.45
Glycosaminoglycans and their proteoglycans: host-associated molecular patterns for initiation and modulation of inflammation. FASEB J (2006) 2.41
Neuroendocrine nicotinic receptor activation increases susceptibility to bacterial infections by suppressing antimicrobial peptide production. Cell Host Microbe (2010) 2.39
Administration of oral vitamin D induces cathelicidin production in atopic individuals. J Allergy Clin Immunol (2008) 2.33
Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin. FASEB J (2006) 2.33
Statins enhance formation of phagocyte extracellular traps. Cell Host Microbe (2010) 2.28
Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum. J Allergy Clin Immunol (2009) 2.20
Anti-fungal activity of cathelicidins and their potential role in Candida albicans skin infection. J Invest Dermatol (2005) 2.19
The antimicrobial protein REG3A regulates keratinocyte proliferation and differentiation after skin injury. Immunity (2012) 2.17
Selective killing of vaccinia virus by LL-37: implications for eczema vaccinatum. J Immunol (2004) 2.16
Selective antimicrobial action is provided by phenol-soluble modulins derived from Staphylococcus epidermidis, a normal resident of the skin. J Invest Dermatol (2010) 2.13
D-alanylation of teichoic acids promotes group a streptococcus antimicrobial peptide resistance, neutrophil survival, and epithelial cell invasion. J Bacteriol (2005) 2.04
Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers. J Invest Dermatol (2007) 2.02
Interplay between antibacterial effectors: a macrophage antimicrobial peptide impairs intracellular Salmonella replication. Proc Natl Acad Sci U S A (2004) 2.00
NLRP3/cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury. J Biol Chem (2009) 1.91
Cathelicidin deficiency predisposes to eczema herpeticum. J Allergy Clin Immunol (2006) 1.88
Control of the innate epithelial antimicrobial response is cell-type specific and dependent on relevant microenvironmental stimuli. Immunology (2006) 1.88
N-glycolylneuraminic acid deficiency in mice: implications for human biology and evolution. Mol Cell Biol (2007) 1.87
Dermatan sulfate: new functions from an old glycosaminoglycan. Glycobiology (2002) 1.87
Cathelicidin mediates innate intestinal defense against colonization with epithelial adherent bacterial pathogens. J Immunol (2005) 1.86
Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons. J Exp Med (2010) 1.85
Antimicrobial peptides and the skin immune defense system. J Allergy Clin Immunol (2008) 1.85
Cutaneous defense mechanisms by antimicrobial peptides. J Invest Dermatol (2005) 1.85
Neutrophil-derived cathelicidin protects from neointimal hyperplasia. Sci Transl Med (2011) 1.84
Neutrophil-derived cathelicidin promotes adhesion of classical monocytes. Circ Res (2013) 1.80
The 2011 Dietary Reference Intakes for Calcium and Vitamin D: what dietetics practitioners need to know. J Am Diet Assoc (2011) 1.80
M1 protein allows Group A streptococcal survival in phagocyte extracellular traps through cathelicidin inhibition. J Innate Immun (2009) 1.80
Cutting edge: mast cell antimicrobial activity is mediated by expression of cathelicidin antimicrobial peptide. J Immunol (2003) 1.79
Activation of TLR2 by a small molecule produced by Staphylococcus epidermidis increases antimicrobial defense against bacterial skin infections. J Invest Dermatol (2010) 1.79
The neuroendocrine peptide catestatin is a cutaneous antimicrobial and induced in the skin after injury. J Invest Dermatol (2008) 1.79
Structure-function relationships among human cathelicidin peptides: dissociation of antimicrobial properties from host immunostimulatory activities. J Immunol (2005) 1.78
Tight junction defects in patients with atopic dermatitis. J Allergy Clin Immunol (2010) 1.77
Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions. Sci Transl Med (2011) 1.74
Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense. J Immunol (2004) 1.74
Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice. J Clin Invest (2007) 1.72
Antimicrobial and protease inhibitory functions of the human cathelicidin (hCAP18/LL-37) prosequence. J Invest Dermatol (2003) 1.70
Cathelicidins, essential gene-encoded mammalian antibiotics. J Mol Med (Berl) (2002) 1.68
Ultraviolet radiation damages self noncoding RNA and is detected by TLR3. Nat Med (2012) 1.68
Activation of TLR3 in keratinocytes increases expression of genes involved in formation of the epidermis, lipid accumulation, and epidermal organelles. J Invest Dermatol (2013) 1.68
Cathelin-related antimicrobial peptide differentially regulates T- and B-cell function. Eur J Immunol (2011) 1.67
The mammalian ionic environment dictates microbial susceptibility to antimicrobial defense peptides. FASEB J (2006) 1.66
Keratinocyte production of cathelicidin provides direct activity against bacterial skin pathogens. Infect Immun (2005) 1.60
Antibodies elicited by inactivated propionibacterium acnes-based vaccines exert protective immunity and attenuate the IL-8 production in human sebocytes: relevance to therapy for acne vulgaris. J Invest Dermatol (2008) 1.55
Interleukin-10 downregulates anti-microbial peptide expression in atopic dermatitis. J Invest Dermatol (2005) 1.54
Bcl-3 acts as an innate immune modulator by controlling antimicrobial responses in keratinocytes. J Invest Dermatol (2009) 1.52
The microbiome extends to subepidermal compartments of normal skin. Nat Commun (2013) 1.52
Expression of LL-37 by human gastric epithelial cells as a potential host defense mechanism against Helicobacter pylori. Gastroenterology (2003) 1.51
Keratinocytes store the antimicrobial peptide cathelicidin in lamellar bodies. J Invest Dermatol (2005) 1.48
Cathelicidin anti-microbial peptide expression in sweat, an innate defense system for the skin. J Invest Dermatol (2002) 1.47
Adrenocorticotropin hormone stimulates interleukin-18 expression in human HaCaT keratinocytes. J Invest Dermatol (2007) 1.45
Cathelicidin antimicrobial peptides block dendritic cell TLR4 activation and allergic contact sensitization. J Immunol (2007) 1.42
Induction of the antimicrobial peptide CRAMP in the blood-brain barrier and meninges after meningococcal infection. Infect Immun (2006) 1.41
The molecular pathology of rosacea. J Dermatol Sci (2009) 1.41
Lack of neutrophil-derived CRAMP reduces atherosclerosis in mice. Circ Res (2012) 1.38
Fermentation of Propionibacterium acnes, a commensal bacterium in the human skin microbiome, as skin probiotics against methicillin-resistant Staphylococcus aureus. PLoS One (2013) 1.38
Genetic variants in thymic stromal lymphopoietin are associated with atopic dermatitis and eczema herpeticum. J Allergy Clin Immunol (2010) 1.38
Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis. J Cell Biol (2007) 1.36
Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris. J Invest Dermatol (2009) 1.35
Antimicrobial peptides: old molecules with new ideas. J Invest Dermatol (2011) 1.34
Cathelicidins and innate defense against invasive bacterial infection. Scand J Infect Dis (2003) 1.33
Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci (2007) 1.33
A group B streptococcal pilus protein promotes phagocyte resistance and systemic virulence. FASEB J (2008) 1.31
IL-17A enhances vitamin D3-induced expression of cathelicidin antimicrobial peptide in human keratinocytes. J Immunol (2008) 1.31
Expression of an additional cathelicidin antimicrobial peptide protects against bacterial skin infection. Proc Natl Acad Sci U S A (2005) 1.26
Collagen synthesis is suppressed in dermal fibroblasts by the human antimicrobial peptide LL-37. J Invest Dermatol (2008) 1.26
Sebum free fatty acids enhance the innate immune defense of human sebocytes by upregulating beta-defensin-2 expression. J Invest Dermatol (2009) 1.23
Neutrophil differentiation into a unique hybrid population exhibiting dual phenotype and functionality of neutrophils and dendritic cells. Blood (2013) 1.23
Functions of the skin microbiota in health and disease. Semin Immunol (2013) 1.22
Structural and sequence motifs in dermatan sulfate for promoting fibroblast growth factor-2 (FGF-2) and FGF-7 activity. J Biol Chem (2004) 1.22
Heterogeneous expression of human cathelicidin hCAP18/LL-37 in inflammatory bowel diseases. Eur J Gastroenterol Hepatol (2006) 1.21
Cathelicidin-related antimicrobial peptide is required for effective lung mucosal immunity in Gram-negative bacterial pneumonia. J Immunol (2012) 1.20
Mast cell cathelicidin antimicrobial peptide prevents invasive group A Streptococcus infection of the skin. J Immunol (2008) 1.20
TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes. J Invest Dermatol (2010) 1.18
Antimicrobial peptides in human skin disease. Eur J Dermatol (2007) 1.17
Staphylococcus epidermidis antimicrobial delta-toxin (phenol-soluble modulin-gamma) cooperates with host antimicrobial peptides to kill group A Streptococcus. PLoS One (2010) 1.17
M1T1 group A streptococcal pili promote epithelial colonization but diminish systemic virulence through neutrophil extracellular entrapment. J Mol Med (Berl) (2009) 1.17
Antimicrobial peptides and the skin immune defense system. J Allergy Clin Immunol (2009) 1.16
Engagement of CD44 by hyaluronan suppresses TLR4 signaling and the septic response to LPS. Mol Immunol (2009) 1.16
Neonatal skin in mice and humans expresses increased levels of antimicrobial peptides: innate immunity during development of the adaptive response. Pediatr Res (2003) 1.15
Flagellin stimulates protective lung mucosal immunity: role of cathelicidin-related antimicrobial peptide. J Immunol (2010) 1.15
Dermatan sulfate binds and potentiates activity of keratinocyte growth factor (FGF-7). J Biol Chem (2002) 1.11
Developmental switch of intestinal antimicrobial peptide expression. J Exp Med (2008) 1.11
Kallikrein expression and cathelicidin processing are independently controlled in keratinocytes by calcium, vitamin D(3), and retinoic acid. J Invest Dermatol (2010) 1.09
Cathelicidin antimicrobial peptide LL-37 in psoriasis enables keratinocyte reactivity against TLR9 ligands. J Invest Dermatol (2011) 1.09
Neutrophil antimicrobial defense against Staphylococcus aureus is mediated by phagolysosomal but not extracellular trap-associated cathelicidin. J Leukoc Biol (2009) 1.08