Published in J Invest Dermatol on October 18, 2007
Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev (2008) 5.28
Update in vitamin D. J Clin Endocrinol Metab (2010) 4.48
Nonclassic actions of vitamin D. J Clin Endocrinol Metab (2008) 3.71
AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense. Trends Immunol (2009) 3.40
Commensal bacteria regulate Toll-like receptor 3-dependent inflammation after skin injury. Nat Med (2009) 3.32
The nonskeletal effects of vitamin D: an Endocrine Society scientific statement. Endocr Rev (2012) 2.71
Respiratory epithelial cells convert inactive vitamin D to its active form: potential effects on host defense. J Immunol (2008) 2.70
Antimicrobial peptides and the skin immune defense system. J Allergy Clin Immunol (2008) 1.85
Activation of TLR2 by a small molecule produced by Staphylococcus epidermidis increases antimicrobial defense against bacterial skin infections. J Invest Dermatol (2010) 1.79
Vitamin D and cancer: a review of molecular mechanisms. Biochem J (2012) 1.51
Vitamin D metabolism and function in the skin. Mol Cell Endocrinol (2011) 1.40
Antimicrobial peptides: old molecules with new ideas. J Invest Dermatol (2011) 1.34
The retinoid X receptors and their ligands. Biochim Biophys Acta (2011) 1.32
IL-17A enhances vitamin D3-induced expression of cathelicidin antimicrobial peptide in human keratinocytes. J Immunol (2008) 1.31
Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation. J Invest Dermatol (2008) 1.24
Antimicrobial implications of vitamin D. Dermatoendocrinol (2011) 1.24
Phenylbutyrate induces antimicrobial peptide expression. Antimicrob Agents Chemother (2009) 1.21
Regulation of cathelicidin antimicrobial peptide expression by an endoplasmic reticulum (ER) stress signaling, vitamin D receptor-independent pathway. J Biol Chem (2011) 1.20
Vitamin D analogs differentially control antimicrobial peptide/"alarmin" expression in psoriasis. PLoS One (2009) 1.17
Genome-wide mapping of gene-microbiota interactions in susceptibility to autoimmune skin blistering. Nat Commun (2013) 1.14
Staphylococcus aureus Colonization: Modulation of Host Immune Response and Impact on Human Vaccine Design. Front Immunol (2014) 1.13
The effect of calcipotriol on the expression of human beta defensin-2 and LL-37 in cultured human keratinocytes. Clin Dev Immunol (2010) 1.13
1,25 dihydroxyvitamin D-mediated orchestration of anticancer, transcript-level effects in the immortalized, non-transformed prostate epithelial cell line, RWPE1. BMC Genomics (2010) 1.05
Host- and microbe determinants that may influence the success of S. aureus colonization. Front Cell Infect Microbiol (2012) 1.03
Vitamin D and the skin: Physiology and pathophysiology. Rev Endocr Metab Disord (2012) 1.03
Vitamin D and the skin. J Bone Miner Metab (2010) 1.03
The dietary histone deacetylase inhibitor sulforaphane induces human beta-defensin-2 in intestinal epithelial cells. Immunology (2008) 1.02
Toll-like receptors in skin infections and inflammatory diseases. Infect Disord Drug Targets (2008) 0.99
The transcriptional coactivator DRIP/mediator complex is involved in vitamin D receptor function and regulates keratinocyte proliferation and differentiation. J Invest Dermatol (2010) 0.97
The Human Cathelicidin Antimicrobial Peptide LL-37 as a Potential Treatment for Polymicrobial Infected Wounds. Front Immunol (2013) 0.97
Role of infection in the development and exacerbation of asthma. Expert Rev Respir Med (2010) 0.95
The vitamin D pathway: a new target for control of the skin's immune response? Exp Dermatol (2008) 0.93
Chromatin acetylation at transcription start sites and vitamin D receptor binding regions relates to effects of 1α,25-dihydroxyvitamin D3 and histone deacetylase inhibitors on gene expression. Nucleic Acids Res (2012) 0.89
Vitamin D regulation of cathelicidin in the skin: toward a renaissance of vitamin D in dermatology? J Invest Dermatol (2008) 0.89
Inflammatory and antimicrobial responses to methicillin-resistant Staphylococcus aureus in an in vitro wound infection model. PLoS One (2013) 0.86
Cholinergic regulation of keratinocyte innate immunity and permeability barrier integrity: new perspectives in epidermal immunity and disease. J Invest Dermatol (2011) 0.85
Vitamin D every day to keep the infection away? Nutrients (2015) 0.85
Induction of porcine host defense peptide gene expression by short-chain fatty acids and their analogs. PLoS One (2013) 0.85
Transcriptional effects of 1,25 dihydroxyvitamin D(3) physiological and supra-physiological concentrations in breast cancer organotypic culture. BMC Cancer (2013) 0.84
Mechanisms Underlying the Regulation of Innate and Adaptive Immunity by Vitamin D. Nutrients (2015) 0.84
Antimicrobial anxiety: the impact of stress on antimicrobial immunity. J Leukoc Biol (2010) 0.83
Resveratrol stimulates sphingosine-1-phosphate signaling of cathelicidin production. J Invest Dermatol (2013) 0.82
Differential regulation of epidermal function by VDR coactivators. J Steroid Biochem Mol Biol (2010) 0.81
Synergistic induction of human cathelicidin antimicrobial peptide gene expression by vitamin D and stilbenoids. Mol Nutr Food Res (2013) 0.80
Vitamin d, the cutaneous barrier, antimicrobial peptides and allergies: is there a link? Allergy Asthma Immunol Res (2013) 0.80
Histone deacetylase inhibitors up-regulate LL-37 expression independent of toll-like receptor mediated signalling in airway epithelial cells. J Inflamm (Lond) (2013) 0.80
Cell-Type Specific Determinants of NRAMP1 Expression in Professional Phagocytes. Biology (Basel) (2013) 0.79
The dietary ingredient, genistein, stimulates cathelicidin antimicrobial peptide expression through a novel S1P-dependent mechanism. J Nutr Biochem (2014) 0.79
Temporins A and B stimulate migration of HaCaT keratinocytes and kill intracellular Staphylococcus aureus. Antimicrob Agents Chemother (2014) 0.79
Impact of vitamin D3 on cutaneous immunity and antimicrobial peptide expression. Dermatoendocrinol (2011) 0.79
Alveolar macrophage cathelicidin deficiency in severe sarcoidosis. J Innate Immun (2012) 0.78
Vitamin D in organ transplantation. Osteoporos Int (2011) 0.78
Microbiome precision editing: Using PEG as a selective fermentation initiator against methicillin-resistant Staphylococcus aureus. Biotechnol J (2016) 0.75
1,25-Dihydroxyvitamin-D3 Induces Avian β-Defensin Gene Expression in Chickens. PLoS One (2016) 0.75
Serum 25-hydroxyvitamin D as a predictor of hospitalization-free survival in predialysis and dialysis patients with chronic kidney disease: a single-center prospective observational analysis. Kidney Res Clin Pract (2016) 0.75
Vitamin D-deficient mice have more invasive urinary tract infection. PLoS One (2017) 0.75
Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science (2006) 18.74
The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab (2010) 13.29
Endogenous antimicrobial peptides and skin infections in atopic dermatitis. N Engl J Med (2002) 9.01
The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection. Nat Med (2006) 5.20
Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism. J Clin Invest (2007) 3.82
HIF-1alpha expression regulates the bactericidal capacity of phagocytes. J Clin Invest (2005) 3.77
Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea. Nat Med (2007) 3.75
AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense. Trends Immunol (2009) 3.40
Cytokine milieu of atopic dermatitis skin subverts the innate immune response to vaccinia virus. Immunity (2006) 3.39
Commensal bacteria regulate Toll-like receptor 3-dependent inflammation after skin injury. Nat Med (2009) 3.32
Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages. Sci Transl Med (2011) 3.27
An angiogenic role for the human peptide antibiotic LL-37/hCAP-18. J Clin Invest (2003) 3.19
Recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on Toll-like receptor 4, CD44, and MD-2. J Biol Chem (2007) 2.82
Hyaluronan fragments stimulate endothelial recognition of injury through TLR4. J Biol Chem (2004) 2.81
IOM committee members respond to Endocrine Society vitamin D guideline. J Clin Endocrinol Metab (2012) 2.75
The nonskeletal effects of vitamin D: an Endocrine Society scientific statement. Endocr Rev (2012) 2.71
Vitamin D3 down-regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen-associated molecular patterns. Eur J Immunol (2006) 2.51
Glycosaminoglycans and their proteoglycans: host-associated molecular patterns for initiation and modulation of inflammation. FASEB J (2006) 2.41
Neuroendocrine nicotinic receptor activation increases susceptibility to bacterial infections by suppressing antimicrobial peptide production. Cell Host Microbe (2010) 2.39
Administration of oral vitamin D induces cathelicidin production in atopic individuals. J Allergy Clin Immunol (2008) 2.33
Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin. FASEB J (2006) 2.33
Statins enhance formation of phagocyte extracellular traps. Cell Host Microbe (2010) 2.28
Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum. J Allergy Clin Immunol (2009) 2.20
Anti-fungal activity of cathelicidins and their potential role in Candida albicans skin infection. J Invest Dermatol (2005) 2.19
The antimicrobial protein REG3A regulates keratinocyte proliferation and differentiation after skin injury. Immunity (2012) 2.17
Selective killing of vaccinia virus by LL-37: implications for eczema vaccinatum. J Immunol (2004) 2.16
Convergence of IL-1beta and VDR activation pathways in human TLR2/1-induced antimicrobial responses. PLoS One (2009) 2.14
Selective antimicrobial action is provided by phenol-soluble modulins derived from Staphylococcus epidermidis, a normal resident of the skin. J Invest Dermatol (2010) 2.13
D-alanylation of teichoic acids promotes group a streptococcus antimicrobial peptide resistance, neutrophil survival, and epithelial cell invasion. J Bacteriol (2005) 2.04
Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers. J Invest Dermatol (2007) 2.02
Interplay between antibacterial effectors: a macrophage antimicrobial peptide impairs intracellular Salmonella replication. Proc Natl Acad Sci U S A (2004) 2.00
NLRP3/cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury. J Biol Chem (2009) 1.91
Cathelicidin deficiency predisposes to eczema herpeticum. J Allergy Clin Immunol (2006) 1.88
Control of the innate epithelial antimicrobial response is cell-type specific and dependent on relevant microenvironmental stimuli. Immunology (2006) 1.88
N-glycolylneuraminic acid deficiency in mice: implications for human biology and evolution. Mol Cell Biol (2007) 1.87
Dermatan sulfate: new functions from an old glycosaminoglycan. Glycobiology (2002) 1.87
Cathelicidin mediates innate intestinal defense against colonization with epithelial adherent bacterial pathogens. J Immunol (2005) 1.86
Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons. J Exp Med (2010) 1.85
Antimicrobial peptides and the skin immune defense system. J Allergy Clin Immunol (2008) 1.85
Cutaneous defense mechanisms by antimicrobial peptides. J Invest Dermatol (2005) 1.85
Neutrophil-derived cathelicidin protects from neointimal hyperplasia. Sci Transl Med (2011) 1.84
Neutrophil-derived cathelicidin promotes adhesion of classical monocytes. Circ Res (2013) 1.80
The 2011 Dietary Reference Intakes for Calcium and Vitamin D: what dietetics practitioners need to know. J Am Diet Assoc (2011) 1.80
M1 protein allows Group A streptococcal survival in phagocyte extracellular traps through cathelicidin inhibition. J Innate Immun (2009) 1.80
Cutting edge: mast cell antimicrobial activity is mediated by expression of cathelicidin antimicrobial peptide. J Immunol (2003) 1.79
Activation of TLR2 by a small molecule produced by Staphylococcus epidermidis increases antimicrobial defense against bacterial skin infections. J Invest Dermatol (2010) 1.79
The neuroendocrine peptide catestatin is a cutaneous antimicrobial and induced in the skin after injury. J Invest Dermatol (2008) 1.79
Structure-function relationships among human cathelicidin peptides: dissociation of antimicrobial properties from host immunostimulatory activities. J Immunol (2005) 1.78
Tight junction defects in patients with atopic dermatitis. J Allergy Clin Immunol (2010) 1.77
Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions. Sci Transl Med (2011) 1.74
Regulation of human epidermal keratinocyte differentiation by the vitamin D receptor and its coactivators DRIP205, SRC2, and SRC3. J Invest Dermatol (2006) 1.74
Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense. J Immunol (2004) 1.74
Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice. J Clin Invest (2007) 1.72
Antimicrobial and protease inhibitory functions of the human cathelicidin (hCAP18/LL-37) prosequence. J Invest Dermatol (2003) 1.70
The role of the calcium sensing receptor in regulating intracellular calcium handling in human epidermal keratinocytes. J Invest Dermatol (2006) 1.70
Cathelicidins, essential gene-encoded mammalian antibiotics. J Mol Med (Berl) (2002) 1.68
Ultraviolet radiation damages self noncoding RNA and is detected by TLR3. Nat Med (2012) 1.68
Activation of TLR3 in keratinocytes increases expression of genes involved in formation of the epidermis, lipid accumulation, and epidermal organelles. J Invest Dermatol (2013) 1.68
Cathelin-related antimicrobial peptide differentially regulates T- and B-cell function. Eur J Immunol (2011) 1.67
The mammalian ionic environment dictates microbial susceptibility to antimicrobial defense peptides. FASEB J (2006) 1.66
Coactivator MED1 ablation in keratinocytes results in hair-cycling defects and epidermal alterations. J Invest Dermatol (2011) 1.64
PTH differentially regulates expression of RANKL and OPG. J Bone Miner Res (2003) 1.61
Keratinocyte production of cathelicidin provides direct activity against bacterial skin pathogens. Infect Immun (2005) 1.60
Antibodies elicited by inactivated propionibacterium acnes-based vaccines exert protective immunity and attenuate the IL-8 production in human sebocytes: relevance to therapy for acne vulgaris. J Invest Dermatol (2008) 1.55
Interleukin-10 downregulates anti-microbial peptide expression in atopic dermatitis. J Invest Dermatol (2005) 1.54
The role of mitogen-activated protein kinase-activated protein kinase 2 in the p38/TNF-alpha pathway of systemic and cutaneous inflammation. J Invest Dermatol (2009) 1.53
LncRNA: a new player in 1α, 25(OH)(2) vitamin D(3) /VDR protection against skin cancer formation. Exp Dermatol (2014) 1.53
Bcl-3 acts as an innate immune modulator by controlling antimicrobial responses in keratinocytes. J Invest Dermatol (2009) 1.52
The microbiome extends to subepidermal compartments of normal skin. Nat Commun (2013) 1.52
Expression of LL-37 by human gastric epithelial cells as a potential host defense mechanism against Helicobacter pylori. Gastroenterology (2003) 1.51
Keratinocytes store the antimicrobial peptide cathelicidin in lamellar bodies. J Invest Dermatol (2005) 1.48
Cathelicidin anti-microbial peptide expression in sweat, an innate defense system for the skin. J Invest Dermatol (2002) 1.47
Adrenocorticotropin hormone stimulates interleukin-18 expression in human HaCaT keratinocytes. J Invest Dermatol (2007) 1.45
Cathelicidin antimicrobial peptides block dendritic cell TLR4 activation and allergic contact sensitization. J Immunol (2007) 1.42
Induction of the antimicrobial peptide CRAMP in the blood-brain barrier and meninges after meningococcal infection. Infect Immun (2006) 1.41
The molecular pathology of rosacea. J Dermatol Sci (2009) 1.41
Vitamin D: beyond bone. Ann N Y Acad Sci (2013) 1.39
Lack of neutrophil-derived CRAMP reduces atherosclerosis in mice. Circ Res (2012) 1.38
Fermentation of Propionibacterium acnes, a commensal bacterium in the human skin microbiome, as skin probiotics against methicillin-resistant Staphylococcus aureus. PLoS One (2013) 1.38
Genetic variants in thymic stromal lymphopoietin are associated with atopic dermatitis and eczema herpeticum. J Allergy Clin Immunol (2010) 1.38
Inactivation of the calcium sensing receptor inhibits E-cadherin-mediated cell-cell adhesion and calcium-induced differentiation in human epidermal keratinocytes. J Biol Chem (2007) 1.38
Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis. J Cell Biol (2007) 1.36
Role of IGF-I signaling in regulating osteoclastogenesis. J Bone Miner Res (2006) 1.36
Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris. J Invest Dermatol (2009) 1.35
Antimicrobial peptides: old molecules with new ideas. J Invest Dermatol (2011) 1.34
The recruitment of phosphatidylinositol 3-kinase to the E-cadherin-catenin complex at the plasma membrane is required for calcium-induced phospholipase C-gamma1 activation and human keratinocyte differentiation. J Biol Chem (2007) 1.34
Lack of the vitamin D receptor is associated with reduced epidermal differentiation and hair follicle growth. J Invest Dermatol (2002) 1.34
Cathelicidins and innate defense against invasive bacterial infection. Scand J Infect Dis (2003) 1.33
Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci (2007) 1.33
IGF-I receptor is required for the anabolic actions of parathyroid hormone on bone. J Bone Miner Res (2007) 1.32
Insulin-like growth factor-I is essential for embryonic bone development. Endocrinology (2006) 1.32