Published in Health Technol Assess on March 01, 2005
CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. BMJ (2010) 28.70
SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials. BMJ (2013) 9.01
Maintaining confidentiality of interim data to enhance trial integrity and credibility. Clin Trials (2008) 2.26
Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial. Trials (2009) 1.81
Adaptive trial design: could we use this approach to improve clinical trials in the field of global health? Am J Trop Med Hyg (2011) 1.60
Clinical trials have gone global: is this a good thing? PLoS Med (2012) 1.58
Outpatient versus inpatient uterine polyp treatment for abnormal uterine bleeding: randomised controlled non-inferiority study. BMJ (2015) 1.44
Stopping clinical trials early. BMJ (2004) 1.05
Reporting of clinical trials: a review of research funders' guidelines. Trials (2008) 1.02
Podoconiosis treatment in northern Ethiopia (GoLBet): study protocol for a randomised controlled trial. Trials (2015) 1.02
Coordination and management of multisite complementary and alternative medicine (CAM) therapies: experience from a multisite reflexology intervention trial. Contemp Clin Trials (2011) 0.97
Data sharing among data monitoring committees and responsibilities to patients and science. Trials (2013) 0.96
Evaluation of partnerships in a transnational family violence prevention network using an integrated knowledge translation and exchange model: a mixed methods study. Health Res Policy Syst (2014) 0.91
The Prevention of Delirium and Complications Associated with Surgical Treatments (PODCAST) study: protocol for an international multicentre randomised controlled trial. BMJ Open (2014) 0.86
The OPTIMIST-A trial: evaluation of minimally-invasive surfactant therapy in preterm infants 25-28 weeks gestation. BMC Pediatr (2014) 0.86
Experiences and challenges in data monitoring for clinical trials within an international tropical disease research network. Clin Trials (2006) 0.82
The contribution of advisory committees and public involvement to large studies: case study. BMC Health Serv Res (2010) 0.82
Protecting clinical trial participants and protecting data integrity: are we meeting the challenges? PLoS Med (2012) 0.80
Exploring the role and function of trial steering committees: results of an expert panel meeting. Trials (2015) 0.80
Stopping guidelines for an effectiveness trial: what should the protocol specify? Trials (2016) 0.79
Approaches to interim analysis of cancer randomised clinical trials with time to event endpoints: a survey from the Italian National Monitoring Centre for Clinical Trials. Trials (2008) 0.77
Trial Sequential Analysis in systematic reviews with meta-analysis. BMC Med Res Methodol (2017) 0.76
Sharing interim trial results by the Data Safety Monitoring Board with those responsible for the trial's conduct and progress: a narrative review. Trials (2017) 0.75
Protocol for the Electroencephalography Guidance of Anesthesia to Alleviate Geriatric Syndromes (ENGAGES) study: a pragmatic, randomised clinical trial. BMJ Open (2016) 0.75
Advantages of Bayesian monitoring methods in deciding whether and when to stop a clinical trial: an example of a neonatal cooling trial. Trials (2016) 0.75
External data required timely response by the Trial Steering-Data Monitoring Committee for the NALoxone InVEstigation (N-ALIVE) pilot trial. Contemp Clin Trials Commun (2017) 0.75
A systematic review of the reporting of Data Monitoring Committees' roles, interim analysis and early termination in pediatric clinical trials. BMC Pediatr (2009) 0.75
Community-based InterVentions to prevent serIous Complications (CIVIC) following spinal cord injury in Bangladesh: protocol of a randomised controlled trial. BMJ Open (2016) 0.75
Early versus late BCG vaccination in HIV-1-exposed infants in Uganda: study protocol for a randomized controlled trial. Trials (2017) 0.75
Statistical methods for assessing agreement between two methods of clinical measurement. Lancet (1986) 211.50
Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. JAMA (1995) 45.41
The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials. Lancet (2001) 31.74
Measuring agreement in method comparison studies. Stat Methods Med Res (1999) 31.11
Multiple significance tests: the Bonferroni method. BMJ (1995) 23.46
Systematic reviews in health care: Assessing the quality of controlled clinical trials. BMJ (2001) 20.65
Confidence intervals rather than P values: estimation rather than hypothesis testing. Br Med J (Clin Res Ed) (1986) 18.51
Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial. Biometrics (1975) 18.25
Analysis of serial measurements in medical research. BMJ (1990) 16.69
British Regional Heart Study: cardiovascular risk factors in middle-aged men in 24 towns. Br Med J (Clin Res Ed) (1981) 14.25
Cronbach's alpha. BMJ (1997) 13.79
The scandal of poor medical research. BMJ (1994) 11.58
Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet (1992) 11.50
The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials. Ann Intern Med (2001) 11.48
Statistical guidelines for contributors to medical journals. Br Med J (Clin Res Ed) (1983) 10.90
Statistics notes. Logarithms. BMJ (1996) 10.56
Statistics in medical journals. Stat Med (1983) 9.80
Subgroup analysis and other (mis)uses of baseline data in clinical trials. Lancet (2000) 9.80
Evaluating non-randomised intervention studies. Health Technol Assess (2003) 9.69
Comparing methods of measurement: why plotting difference against standard method is misleading. Lancet (1995) 9.14
Statistics notes: Analysing controlled trials with baseline and follow up measurements. BMJ (2001) 8.98
Paclitaxel plus platinum-based chemotherapy versus conventional platinum-based chemotherapy in women with relapsed ovarian cancer: the ICON4/AGO-OVAR-2.2 trial. Lancet (2003) 8.88
Statistics and ethics in medical research: III How large a sample? Br Med J (1980) 8.78
Statistical problems in the reporting of clinical trials. A survey of three medical journals. N Engl J Med (1987) 8.64
Better reporting of randomised controlled trials: the CONSORT statement. BMJ (1996) 8.39
More informative abstracts revisited. Ann Intern Med (1990) 8.26
Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomised study. Lancet (2008) 8.12
Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trial. Lancet (2009) 7.96
Repeated measures in clinical trials: analysis using mean summary statistics and its implications for design. Stat Med (1992) 7.33
Laparoscopic versus open inguinal hernia repair: randomised prospective trial. Lancet (1994) 6.91
Transforming data. BMJ (1996) 6.78
Regression towards the mean. BMJ (1994) 6.57
Measurement error. BMJ (1996) 6.18
Reliability of league tables of in vitro fertilisation clinics: retrospective analysis of live birth rates. BMJ (1998) 5.96
Assessing the quality of randomization from reports of controlled trials published in obstetrics and gynecology journals. JAMA (1994) 5.80
Risk of bacterial infection associated with allogeneic blood transfusion among patients undergoing hip fracture repair. Transfusion (1999) 5.67
Statistics notes. The odds ratio. BMJ (2000) 5.61
British Regional Heart Study: geographic variations in cardiovascular mortality, and the role of water quality. Br Med J (1980) 5.56
Risk factors for ischaemic heart disease: the prospective phase of the British Regional Heart Study. J Epidemiol Community Health (1985) 5.53
The CONSORT statement: revised recommendations for improving the quality of reports of parallel group randomized trials. BMC Med Res Methodol (2001) 5.43
Applying the right statistics: analyses of measurement studies. Ultrasound Obstet Gynecol (2003) 5.40
How can medical journals help prevent poor medical research? Some opportunities presented by electronic publishing. Lancet (1999) 5.27
Statistics notes. Interaction 2: Compare effect sizes not P values. BMJ (1996) 5.18
Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women. J Am Coll Cardiol (1994) 5.02
Maternal vitamin D intake and mineral metabolism in mothers and their newborn infants. Br Med J (1980) 4.97
Correlation, regression, and repeated data. BMJ (1994) 4.88
Calculating correlation coefficients with repeated observations: Part 1--Correlation within subjects. BMJ (1995) 4.87
REporting recommendations for tumour MARKer prognostic studies (REMARK). Br J Cancer (2005) 4.85
Social factors and height of primary schoolchildren in England and Scotland. J Epidemiol Community Health (1978) 4.73
A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. Stent Anticoagulation Restenosis Study Investigators. N Engl J Med (1998) 4.68
Randomisation. BMJ (1991) 4.66
Patients' preferences and randomised trials. Lancet (1996) 4.64
Randomized trials or observational tribulations? N Engl J Med (2000) 4.49
Measurement error and correlation coefficients. BMJ (1996) 4.38
Indirect comparisons of competing interventions. Health Technol Assess (2005) 4.33
Statistical aspects of prognostic factor studies in oncology. Br J Cancer (1994) 4.22
Measurement error. BMJ (1996) 4.13
Social class differences in ischaemic heart disease in British men. Lancet (1987) 4.09
Survival analysis part I: basic concepts and first analyses. Br J Cancer (2003) 4.08
Some examples of regression towards the mean. BMJ (1994) 4.01
Survival probabilities (the Kaplan-Meier method). BMJ (1998) 3.98
Impact of allocation concealment on conclusions drawn from meta-analyses of randomized trials. Int J Epidemiol (2007) 3.84
A catalogue of reporting guidelines for health research. Eur J Clin Invest (2010) 3.83
Identifying men at high risk of heart attacks: strategy for use in general practice. Br Med J (Clin Res Ed) (1986) 3.76
Systematic review of the long-term effects and economic consequences of treatments for obesity and implications for health improvement. Health Technol Assess (2004) 3.73
Bayesian approaches to random-effects meta-analysis: a comparative study. Stat Med (1995) 3.71
Neonatal examination and screening trial (NEST): a randomised, controlled, switchback trial of alternative policies for low risk infants. BMJ (1999) 3.63
Effects of a drug overdose in a television drama on presentations to hospital for self poisoning: time series and questionnaire study. BMJ (1999) 3.52
Frequency and reasons for outcome reporting bias in clinical trials: interviews with trialists. BMJ (2011) 3.50
Changes in annual tuberculosis notification rates between 1978/79 and 1983 for the population of Indian subcontinent ethnic origin resident in England. J Epidemiol Community Health (1986) 3.48
The National Survey of Stroke. Clinical findings. Stroke (1981) 3.45
Can meta-analyses be trusted? Lancet (1991) 3.43
The benefits and harms of breast cancer screening: an independent review. Br J Cancer (2013) 3.43
Transformations, means, and confidence intervals. BMJ (1996) 3.42
A systematic review of discharge coding accuracy. J Public Health Med (2001) 3.36
Estimating sample sizes for binary, ordered categorical, and continuous outcomes in two group comparisons. BMJ (1995) 3.35
Measurement error proportional to the mean. BMJ (1996) 3.34
Long-term survival of patients with breast cancer: a study of the curability of the disease. Br Med J (1979) 3.29
National study of health and growth: standards of attained height, weight and triceps skinfold in English children 5 to 11 years old. Ann Hum Biol (1977) 3.23
The use of transformation when comparing two means. BMJ (1996) 3.22
Adjuvant chemotherapy, with or without postoperative radiotherapy, in operable non-small-cell lung cancer: two meta-analyses of individual patient data. Lancet (2010) 3.21
A note on the use of the intraclass correlation coefficient in the evaluation of agreement between two methods of measurement. Comput Biol Med (1990) 3.18
Interaction 3: How to examine heterogeneity. BMJ (1996) 3.17
Missing covariate data within cancer prognostic studies: a review of current reporting and proposed guidelines. Br J Cancer (2004) 3.15
How effective is tailored print communication? Ann Behav Med (1999) 3.10
Survival analysis part II: multivariate data analysis--an introduction to concepts and methods. Br J Cancer (2003) 3.06
Tuberculosis at the end of the 20th century in England and Wales: results of a national survey in 1998. Thorax (2001) 3.01
An epidemiological study of workers producing enzyme washing powders. Lancet (1970) 2.98