Substrate interactions with the nitrogenase active site.

Mechanism of Mo-dependent nitrogenase. Annu Rev Biochem (2009) 3.00

Climbing nitrogenase: toward a mechanism of enzymatic nitrogen fixation. Acc Chem Res (2009) 2.43

Mechanism of nitrogen fixation by nitrogenase: the next stage. Chem Rev (2014) 1.83

How many metals does it take to fix N2? A mechanistic overview of biological nitrogen fixation. Proc Natl Acad Sci U S A (2006) 1.83

Connecting nitrogenase intermediates with the kinetic scheme for N2 reduction by a relaxation protocol and identification of the N2 binding state. Proc Natl Acad Sci U S A (2007) 1.79

A molybdenum complex bearing PNP-type pincer ligands leads to the catalytic reduction of dinitrogen into ammonia. Nat Chem (2010) 1.75

Nitrogenase: a draft mechanism. Acc Chem Res (2013) 1.64

Diazene (HN=NH) is a substrate for nitrogenase: insights into the pathway of N2 reduction. Biochemistry (2007) 1.29

How nitrogenase shakes--initial information about P-cluster and FeMo-cofactor normal modes from nuclear resonance vibrational spectroscopy (NRVS). J Am Chem Soc (2006) 1.28

N2 functionalization at iron metallaboratranes. J Am Chem Soc (2011) 1.25

Formation of {[HIPTN(3)N]Mo(III)H}(-) by heterolytic cleavage of H(2) as established by EPR and ENDOR spectroscopy. Inorg Chem (2010) 1.25

Terminal iron dinitrogen and iron imide complexes supported by a tris(phosphino)borane ligand. Angew Chem Int Ed Engl (2011) 1.23

Molybdenum nitrogenase catalyzes the reduction and coupling of CO to form hydrocarbons. J Biol Chem (2011) 1.20

57Fe ENDOR spectroscopy and 'electron inventory' analysis of the nitrogenase E4 intermediate suggest the metal-ion core of FeMo-cofactor cycles through only one redox couple. J Am Chem Soc (2011) 1.20

Alkyne substrate interaction within the nitrogenase MoFe protein. J Inorg Biochem (2007) 1.18

The reactivity patterns of low-coordinate iron-hydride complexes. J Am Chem Soc (2008) 1.15

Ligand-bound S = 1/2 FeMo-cofactor of nitrogenase: hyperfine interaction analysis and implication for the central ligand X identity. Inorg Chem (2008) 1.07

Carbon dioxide reduction to methane and coupling with acetylene to form propylene catalyzed by remodeled nitrogenase. Proc Natl Acad Sci U S A (2012) 1.06

Controlled expression of nif and isc iron-sulfur protein maturation components reveals target specificity and limited functional replacement between the two systems. J Bacteriol (2007) 1.02

Electron transfer in nitrogenase catalysis. Curr Opin Chem Biol (2012) 1.02

Mechanistic insight into N=N cleavage by a low-coordinate iron(II) hydride complex. J Am Chem Soc (2007) 1.01

Nitrogenase reduction of carbon-containing compounds. Biochim Biophys Acta (2013) 0.97

A substrate channel in the nitrogenase MoFe protein. J Biol Inorg Chem (2009) 0.96

Oxidative group transfer to a triiron complex to form a nucleophilic μ(3)-nitride, [Fe3(μ(3)-N)]-. J Am Chem Soc (2011) 0.95

Evidence for a dynamic role for homocitrate during nitrogen fixation: the effect of substitution at the alpha-Lys426 position in MoFe-protein of Azotobacter vinelandii. Biochem J (2006) 0.94

Alkali metal control over N-N cleavage in iron complexes. J Am Chem Soc (2014) 0.92

EPR study of the low-spin [d(3); S =(1)/(2)], Jahn-Teller-active, dinitrogen complex of a molybdenum trisamidoamine. J Am Chem Soc (2007) 0.91

Molybdenum triamidoamine systems. Reactions involving dihydrogen relevant to catalytic reduction of dinitrogen. Inorg Chem (2009) 0.89

Genetic transformation and mutagenesis via single-stranded DNA in the unicellular, diazotrophic cyanobacteria of the genus Cyanothece. Appl Environ Microbiol (2010) 0.89

Testing the polynuclear hypothesis: multielectron reduction of small molecules by triiron reaction sites. J Am Chem Soc (2013) 0.88

Ammonia formation by a thiolate-bridged diiron amide complex as a nitrogenase mimic. Nat Chem (2013) 0.84

Quantitative geometric descriptions of the belt iron atoms of the iron-molybdenum cofactor of nitrogenase and synthetic iron(II) model complexes. Inorg Chem (2007) 0.84

A molecular pathway for the egress of ammonia produced by nitrogenase. Sci Rep (2013) 0.83

Multiple amino acid sequence alignment nitrogenase component 1: insights into phylogenetics and structure-function relationships. PLoS One (2013) 0.82

Probing the MgATP-bound conformation of the nitrogenase Fe protein by solution small-angle X-ray scattering. Biochemistry (2007) 0.82

Site-isolated redox reactivity in a trinuclear iron complex. Inorg Chem (2012) 0.82

Dinitrogen binding and cleavage by multinuclear iron complexes. Acc Chem Res (2015) 0.82

Advanced paramagnetic resonance spectroscopies of iron-sulfur proteins: Electron nuclear double resonance (ENDOR) and electron spin echo envelope modulation (ESEEM). Biochim Biophys Acta (2015) 0.81

Nitrite and hydroxylamine as nitrogenase substrates: mechanistic implications for the pathway of N₂ reduction. J Am Chem Soc (2014) 0.80

Multimetallic Cooperativity in Activation of Dinitrogen at Iron-Potassium Sites. Chem Sci (2014) 0.79

Synthesis of open-shell, bimetallic Mn/Fe trinuclear clusters. J Am Chem Soc (2013) 0.79

Metal atom lability in polynuclear complexes. Inorg Chem (2013) 0.78

Low-spin pseudotetrahedral iron(I) sites in Fe₂(μ-S) complexes. Angew Chem Int Ed Engl (2014) 0.78

Ligand dependence of binding to three-coordinate Fe(II) complexes. Inorg Chem (2009) 0.78

Low frequency dynamics of the nitrogenase MoFe protein via femtosecond pump probe spectroscopy - Observation of a candidate promoting vibration. J Inorg Biochem (2015) 0.75

Macrocyclic Binucleating β-Diketiminate Ligands and their Lithium, Aluminum, and Zinc Complexes. Organometallics (2007) 0.75

Synthesis of diamidopyrrolyl molybdenum complexes relevant to reduction of dinitrogen to ammonia. Inorg Chem (2010) 0.75

Exploring secondary-sphere interactions in Fe-N x H y complexes relevant to N2 fixation. Chem Sci (2016) 0.75

Coordination chemistry insights into the role of alkali metal promoters in dinitrogen reduction. Catal Today (2016) 0.75

Structure, function, and formation of biological iron-sulfur clusters. Annu Rev Biochem (2005) 6.82

Mechanism of Mo-dependent nitrogenase. Annu Rev Biochem (2009) 3.00

Climbing nitrogenase: toward a mechanism of enzymatic nitrogen fixation. Acc Chem Res (2009) 2.43

An anchoring role for FeS clusters: chelation of the amino acid moiety of S-adenosylmethionine to the unique iron site of the [4Fe-4S] cluster of pyruvate formate-lyase activating enzyme. J Am Chem Soc (2002) 2.16

Testing if the interstitial atom, X, of the nitrogenase molybdenum-iron cofactor is N or C: ENDOR, ESEEM, and DFT studies of the S = 3/2 resting state in multiple environments. Inorg Chem (2007) 2.12

Electron-nuclear double resonance spectroscopic evidence that S-adenosylmethionine binds in contact with the catalytically active [4Fe-4S](+) cluster of pyruvate formate-lyase activating enzyme. J Am Chem Soc (2002) 1.99

Formation of iron-sulfur clusters in bacteria: an emerging field in bioinorganic chemistry. Curr Opin Chem Biol (2003) 1.96

Trapping H- bound to the nitrogenase FeMo-cofactor active site during H2 evolution: characterization by ENDOR spectroscopy. J Am Chem Soc (2005) 1.93

Structure of a cofactor-deficient nitrogenase MoFe protein. Science (2002) 1.91

An organometallic intermediate during alkyne reduction by nitrogenase. J Am Chem Soc (2004) 1.89

Frontiers, opportunities, and challenges in biochemical and chemical catalysis of CO2 fixation. Chem Rev (2013) 1.86

Mechanism of nitrogen fixation by nitrogenase: the next stage. Chem Rev (2014) 1.83

Connecting nitrogenase intermediates with the kinetic scheme for N2 reduction by a relaxation protocol and identification of the N2 binding state. Proc Natl Acad Sci U S A (2007) 1.79

Formation and insertion of the nitrogenase iron-molybdenum cofactor. Chem Rev (2004) 1.77

Formation and properties of [4Fe-4S] clusters on the IscU scaffold protein. Biochemistry (2007) 1.76

The yeast iron regulatory proteins Grx3/4 and Fra2 form heterodimeric complexes containing a [2Fe-2S] cluster with cysteinyl and histidyl ligation. Biochemistry (2009) 1.75

Substrate interactions with nitrogenase: Fe versus Mo. Biochemistry (2004) 1.68

Intermediates trapped during nitrogenase reduction of N triple bond N, CH3-N=NH, and H2N-NH2. J Am Chem Soc (2005) 1.68

Nitrogen fixation: the mechanism of the Mo-dependent nitrogenase. Crit Rev Biochem Mol Biol (2003) 1.65

Genome sequence of Azotobacter vinelandii, an obligate aerobe specialized to support diverse anaerobic metabolic processes. J Bacteriol (2009) 1.64

Nitrogenase: a draft mechanism. Acc Chem Res (2013) 1.64

Electron inventory, kinetic assignment (E(n)), structure, and bonding of nitrogenase turnover intermediates with C2H2 and CO. J Am Chem Soc (2005) 1.57

ENDOR spectroscopy shows that guanine N1 binds to [4Fe-4S] cluster II of the S-adenosylmethionine-dependent enzyme MoaA: mechanistic implications. J Am Chem Soc (2009) 1.54

Purified particulate methane monooxygenase from Methylococcus capsulatus (Bath) is a dimer with both mononuclear copper and a copper-containing cluster. Proc Natl Acad Sci U S A (2003) 1.54

In vitro activation of apo-aconitase using a [4Fe-4S] cluster-loaded form of the IscU [Fe-S] cluster scaffolding protein. Biochemistry (2007) 1.51

Characterization of the particulate methane monooxygenase metal centers in multiple redox states by X-ray absorption spectroscopy. Inorg Chem (2006) 1.50

Spectroscopic approaches to elucidating novel iron-sulfur chemistry in the "radical-Sam" protein superfamily. Inorg Chem (2005) 1.49

Catalytic mechanism of heme oxygenase through EPR and ENDOR of cryoreduced oxy-heme oxygenase and its Asp 140 mutants. J Am Chem Soc (2002) 1.48

Controlled expression and functional analysis of iron-sulfur cluster biosynthetic components within Azotobacter vinelandii. J Bacteriol (2006) 1.46

In vivo iron-sulfur cluster formation. Proc Natl Acad Sci U S A (2008) 1.44

Trapping a hydrazine reduction intermediate on the nitrogenase active site. Biochemistry (2005) 1.44

Coordination and mechanism of reversible cleavage of S-adenosylmethionine by the [4Fe-4S] center in lysine 2,3-aminomutase. J Am Chem Soc (2003) 1.42

Substrate interaction at an iron-sulfur face of the FeMo-cofactor during nitrogenase catalysis. J Biol Chem (2004) 1.40

The metal centers of particulate methane monooxygenase from Methylosinus trichosporium OB3b. Biochemistry (2008) 1.38

(IscS-IscU)2 complex structures provide insights into Fe2S2 biogenesis and transfer. Angew Chem Int Ed Engl (2012) 1.37

Localization of a substrate binding site on the FeMo-cofactor in nitrogenase: trapping propargyl alcohol with an alpha-70-substituted MoFe protein. Biochemistry (2003) 1.37

Iron-sulfur cluster assembly: NifU-directed activation of the nitrogenase Fe protein. J Biol Chem (2004) 1.37

Dynamic docking and electron-transfer between cytochrome b5 and a suite of myoglobin surface-charge mutants. Introduction of a functional-docking algorithm for protein-protein complexes. J Am Chem Soc (2004) 1.37

Is Mo involved in hydride binding by the four-electron reduced (E4) intermediate of the nitrogenase MoFe protein? J Am Chem Soc (2010) 1.33

Diazene (HN=NH) is a substrate for nitrogenase: insights into the pathway of N2 reduction. Biochemistry (2007) 1.29

A methyldiazene (HN=N-CH3)-derived species bound to the nitrogenase active-site FeMo cofactor: Implications for mechanism. Proc Natl Acad Sci U S A (2006) 1.28

A proposed role for the Azotobacter vinelandii NfuA protein as an intermediate iron-sulfur cluster carrier. J Biol Chem (2008) 1.27

Formation of {[HIPTN(3)N]Mo(III)H}(-) by heterolytic cleavage of H(2) as established by EPR and ENDOR spectroscopy. Inorg Chem (2010) 1.25

Probing in vivo Mn2+ speciation and oxidative stress resistance in yeast cells with electron-nuclear double resonance spectroscopy. Proc Natl Acad Sci U S A (2010) 1.25

The copper chelator methanobactin from Methylosinus trichosporium OB3b binds copper(I). J Am Chem Soc (2005) 1.23

Substrate binding to NO-ferro-naphthalene 1,2-dioxygenase studied by high-resolution Q-band pulsed 2H-ENDOR spectroscopy. J Am Chem Soc (2003) 1.22

Dynamic docking and electron transfer between Zn-myoglobin and cytochrome b(5). J Am Chem Soc (2002) 1.22

NifS-mediated assembly of [4Fe-4S] clusters in the N- and C-terminal domains of the NifU scaffold protein. Biochemistry (2005) 1.21

Molybdenum nitrogenase catalyzes the reduction and coupling of CO to form hydrocarbons. J Biol Chem (2011) 1.20

Breaking the N2 triple bond: insights into the nitrogenase mechanism. Dalton Trans (2006) 1.20

57Fe ENDOR spectroscopy and 'electron inventory' analysis of the nitrogenase E4 intermediate suggest the metal-ion core of FeMo-cofactor cycles through only one redox couple. J Am Chem Soc (2011) 1.20

Trapping an intermediate of dinitrogen (N2) reduction on nitrogenase. Biochemistry (2009) 1.20

Localization of a catalytic intermediate bound to the FeMo-cofactor of nitrogenase. J Biol Chem (2004) 1.20

ENDOR/HYSCORE studies of the common intermediate trapped during nitrogenase reduction of N2H2, CH3N2H, and N2H4 support an alternating reaction pathway for N2 reduction. J Am Chem Soc (2011) 1.19