Published in Hepatol Res on April 01, 2005
Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidation. Br J Clin Pharmacol (2006) 1.12
A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study. PLoS One (2012) 0.80
The UDP-glucuronosyltransferases of the blood-brain barrier: their role in drug metabolism and detoxication. Front Cell Neurosci (2014) 0.80
A biochemically defined system for mammalian nonhomologous DNA end joining. Mol Cell (2004) 3.01
Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss. Acta Neuropathol (2013) 1.53
Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex. Genes Dev (2014) 1.25
A single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS). J Exp Med (2003) 1.11
Over-expression of human DNA polymerase lambda in E. coli and characterization of the recombinant enzyme. Genes Cells (2002) 1.09
Pole and global shape of 25143 Itokawa. Science (2006) 1.07
Identification and characterization of the UL56 gene product of herpes simplex virus type 2. J Virol (2002) 1.06
Grb2 and Gads exhibit different interactions with CD28 and play distinct roles in CD28-mediated costimulation. J Immunol (2006) 1.02
Discovery of selective PDE4B inhibitors. Bioorg Med Chem Lett (2009) 1.00
[Case of meningioma with extracranial extension through the internal jugular vein]. No Shinkei Geka (2005) 0.99
Factors contributing to ribavirin-induced anemia. J Gastroenterol Hepatol (2004) 0.99
TERT promoter mutations rather than methylation are the main mechanism for TERT upregulation in adult gliomas. Acta Neuropathol (2013) 0.97
DNA polymerase lambda directly binds to proliferating cell nuclear antigen through its confined C-terminal region. Genes Cells (2005) 0.95
Preliminary results of intensity-modulated radiation therapy with helical tomotherapy for prostate cancer. J Cancer Res Clin Oncol (2012) 0.94
A plant phytotoxin, solanapyrone A, is an inhibitor of DNA polymerase beta and lambda. J Biol Chem (2001) 0.93
Heterocomplex formation by Arp4 and β-actin is involved in the integrity of the Brg1 chromatin remodeling complex. J Cell Sci (2012) 0.91
Autotaxin expression is enhanced in frontal cortex of Alzheimer-type dementia patients. Neurosci Lett (2006) 0.91
IDH1/2 mutation is a prognostic marker for survival and predicts response to chemotherapy for grade II gliomas concomitantly treated with radiation therapy. Int J Oncol (2012) 0.89
Structural relationship of curcumin derivatives binding to the BRCT domain of human DNA polymerase lambda. Genes Cells (2006) 0.88
Identification of functional domains in TdIF1 and its inhibitory mechanism for TdT activity. Genes Cells (2007) 0.88
A sulphoquinovosyl diacylglycerol is a DNA polymerase epsilon inhibitor. Biochem J (2003) 0.88
Impact of combination therapy with repeat surgery and temozolomide for recurrent or progressive glioblastoma multiforme: a prospective trial. Surg Neurol (2007) 0.87
Mass and local topography measurements of Itokawa by Hayabusa. Science (2006) 0.87
BPOZ-2 directly binds to eEF1A1 to promote eEF1A1 ubiquitylation and degradation and prevent translation. Genes Cells (2008) 0.86
Petasiphenol: a DNA polymerase lambda inhibitor. Biochemistry (2002) 0.85
Mucinous carcinoma of the skin with apocrine-type differentiation: immunohistochemical studies. Am J Dermatopathol (2003) 0.85
Functional analyses of mouse ASK, an activation subunit for Cdc7 kinase, using conditional ASK knockout ES cells. Genes Cells (2005) 0.85
Preliminary analysis of risk factors for late rectal toxicity after helical tomotherapy for prostate cancer. J Radiat Res (2013) 0.85
Pathological findings and prognostic factors in recurrent glioblastomas. Brain Tumor Pathol (2012) 0.84
Primary choroid plexus T-cell lymphoma and multiple aneurysms in the CNS. Leuk Lymphoma (2006) 0.84
Rb1cc1 is critical for myoblast differentiation through Rb1 regulation. Virchows Arch (2005) 0.82
Some anti-chronic inflammatory compounds are DNA polymerase lambda-specific inhibitors. Biochem Pharmacol (2003) 0.82
Development of a robust and sensitive pyrosequencing assay for the detection of IDH1/2 mutations in gliomas. Brain Tumor Pathol (2014) 0.81
Fluvoxamine, a selective serotonin reuptake inhibitor, and 5-HT2C receptor inactivation induce appetite-suppressing effects in mice via 5-HT1B receptors. Int J Neuropsychopharmacol (2006) 0.81
A case of otomycosis caused by Aspergillus sclerotiorum. J Dermatol (2004) 0.81
Long-term follow-up of vanishing tumors in the brain: how should a lesion mimicking primary CNS lymphoma be managed? Clin Neurol Neurosurg (2012) 0.80
Hepatitis C virus replication is inhibited by 22beta-methoxyolean-12-ene-3beta, 24(4beta)-diol (ME3738) through enhancing interferon-beta. Hepatology (2008) 0.80
Bood POZ containing gene type 2 is a human counterpart of yeast Btb3p and promotes the degradation of terminal deoxynucleotidyltransferase. Genes Cells (2008) 0.80
Terminal deoxynucleotidyltransferase forms a ternary complex with a novel chromatin remodeling protein with 82 kDa and core histone. Genes Cells (2003) 0.80
Direct binding of TReP-132 with TdT results in reduction of TdT activity. Genes Cells (2006) 0.80
Inhibitory effect of tocotrienol on eukaryotic DNA polymerase lambda and angiogenesis. Biochem Biophys Res Commun (2005) 0.80
Human chorionic gonadotropin is expressed virtually in all intracranial germ cell tumors. J Neurooncol (2015) 0.79
Occurrence of clinical depression during combination therapy with pegylated interferon alpha or natural human interferon beta plus ribavirin. Hepatol Res (2011) 0.79
Revisiting TP53 Mutations and Immunohistochemistry--A Comparative Study in 157 Diffuse Gliomas. Brain Pathol (2014) 0.79
Protective effects of alpha1-acid glycoprotein and serum amyloid A on concanavalin A-induced liver failure via interleukin-6 induction by ME3738. Eur J Pharmacol (2006) 0.79
Lumbosubarachnoid-lumboepidural shunting in patients with idiopathic normal-pressure hydrocephalus: surgical procedures and follow-up study of five cases. Neurol Med Chir (Tokyo) (2013) 0.79
Activation of brain prostanoid EP3 receptors via arachidonic acid cascade during behavioral suppression induced by Delta8-tetrahydrocannabinol. J Neurochem (2004) 0.79
Selective inhibitors of terminal deoxyribonucleotidyltransferase (TdT): baicalin and genistin. Biochim Biophys Acta (2005) 0.78
Secondary glioblastomas with IDH1/2 mutations have longer glioma history from preceding lower-grade gliomas. Brain Tumor Pathol (2013) 0.78
Correlations between Z-scores of VSRAD and regional cerebral blood flow of SPECT in patients with Alzheimer's disease and mild cognitive impairment. Psychiatry Clin Neurosci (2010) 0.78
TdIF2 is a nucleolar protein that promotes rRNA gene promoter activity. Genes Cells (2011) 0.78
Monoacetylcurcumin: a new inhibitor of eukaryotic DNA polymerase lambda and a new ligand for inhibitor-affinity chromatography. Biochem Biophys Res Commun (2005) 0.78
Cholesterol hemisuccinate: a selective inhibitor of family X DNA polymerases. Biochem Biophys Res Commun (2007) 0.77
BRCT domain of DNA polymerase μ has DNA-binding activity and promotes the DNA polymerization activity. Genes Cells (2012) 0.77
ME3738 enhances the effect of interferon and inhibits hepatitis C virus replication both in vitro and in vivo. J Hepatol (2010) 0.77
Human neutrophils isolated from peripheral blood contain Ku protein but not DNA-dependent protein kinase. Int J Biochem Cell Biol (2003) 0.77
Cell density-dependent regulation of tumor necrosis factor alpha gene expression in a human hepatoma cell line. Int J Oncol (2007) 0.76
Preventive effects of ME3738 on hepatic fibrosis induced by bile duct ligation in rats. Hepatol Res (2008) 0.76
TdT interacting factor 1 enhances TdT ubiquitylation through recruitment of BPOZ-2 into nucleus from cytoplasm. Genes Cells (2009) 0.76
Beta-sitosterol-3-O-beta-D-glucopyranoside: a eukaryotic DNA polymerase lambda inhibitor. J Steroid Biochem Mol Biol (2006) 0.76
Correlations between atrophy of the entorhinal cortex and cognitive function in patients with Alzheimer's disease and mild cognitive impairment. Psychiatry Clin Neurosci (2012) 0.76
Direct binding of ligandin to uridine 5'-diphosphate glucuronosyltransferase 1A1. Hepatol Res (2007) 0.76
Hypersensitivity to pentylenetetrazol-induced convulsion in mice lacking the PLC-related inactive protein-1. Brain Res (2004) 0.75
TdIF1 recognizes a specific DNA sequence through its Helix-Turn-Helix and AT-hook motifs to regulate gene transcription. PLoS One (2013) 0.75
Ubiquitylation of terminal deoxynucleotidyltransferase inhibits its activity. PLoS One (2012) 0.75
Establishment of the Commissioning Procedure for Modifying the Beam Model of Helical Tomotherapy. Nihon Hoshasen Gijutsu Gakkai Zasshi (2016) 0.75
Structural analysis of epolactaene derivatives as DNA polymerase inhibitors and anti-inflammatory compounds. Int J Mol Med (2005) 0.75
[Expression and function of terminal deoxynucleotidyl-transferase and discovery of novel DNA polymerase mu]. Seikagaku (2002) 0.75
Increase in platelet count based on inosine triphosphatase genotype during interferon beta plus ribavirin combination therapy. J Gastroenterol Hepatol (2012) 0.75
Definition of the transcription factor TdIF1 consensus-binding sequence through genomewide mapping of its binding sites. Genes Cells (2015) 0.75
Efficacy of prolonged treatment following combination with ribavirin and interferon for chronic hepatitis type C: A pilot study. Hepatol Res (2005) 0.75
5-(Hydroxymethyl)-2-furfural: a selective inhibitor of DNA polymerase lambda and terminal deoxynucleotidyltransferase. Arch Biochem Biophys (2005) 0.75
Molecular action mode of Hippospongic acid A, an inhibitor of gastrulation of starfish embryos. J Biochem (2003) 0.75
Pilot trial of the rate of response, safety, and tolerability of temozolomide and oral VP-16 in patients with recurrent or treatment-induced malignant central nervous system tumors. Surg Neurol (2008) 0.75
Histopathological malignant progression of grade II and III gliomas correlated with IDH1/2 mutation status. Brain Tumor Pathol (2012) 0.75
Weight loss during telaprevir-based triple therapy due to telaprevir-induced appetite loss. Intern Med (2014) 0.75
[Investigation for decrease of delivery time for the prostate cancer patient by modifications of treatment planning parameters in TomoTherapy planning station]. Nihon Hoshasen Gijutsu Gakkai Zasshi (2011) 0.75
Evaluation of parotid gland function using equivalent cross-relaxation rate imaging applied magnetization transfer effect. J Radiat Res (2012) 0.75
Estimation of two real-time RT-PCR assays for quantitation of hepatitis C virus RNA during PEG-IFN plus ribavirin therapy by HCV genotypes and IL28B genotype. J Infect Chemother (2012) 0.75
Effects of rolipram on U46619-induced contraction and cyclic nucleotide content in the porcine coronary artery. J Smooth Muscle Res (2010) 0.75