Published in Genes Cells on March 01, 2006
The targets of curcumin. Curr Drug Targets (2011) 1.76
Multitargeting by curcumin as revealed by molecular interaction studies. Nat Prod Rep (2011) 1.62
A liquid chromatography-tandem mass spectrometric method for quantification of curcuminoids in cell medium and mouse plasma. J Chromatogr B Analyt Technol Biomed Life Sci (2010) 0.98
Inhibitory effects of glycyrrhetinic Acid on DNA polymerase and inflammatory activities. Evid Based Complement Alternat Med (2011) 0.86
Eliminating the heart from the curcumin molecule: monocarbonyl curcumin mimics (MACs). Molecules (2014) 0.85
Evaluation of curcumin acetates and amino acid conjugates as proteasome inhibitors. Int J Mol Med (2010) 0.85
Demethoxycurcumin Is A Potent Inhibitor of P-Type ATPases from Diverse Kingdoms of Life. PLoS One (2016) 0.77
Effects of intermediates between vitamins K(2) and K(3) on mammalian DNA polymerase inhibition and anti-inflammatory activity. Int J Mol Sci (2011) 0.77
Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK. J Clin Oncol (2009) 15.23
The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies. Cancer Cell (2006) 5.34
A G protein-coupled receptor responsive to bile acids. J Biol Chem (2003) 4.76
BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations. PLoS Med (2007) 4.50
Differential effects of gefitinib and cetuximab on non-small-cell lung cancers bearing epidermal growth factor receptor mutations. J Natl Cancer Inst (2005) 4.19
Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancers dependent on the epidermal growth factor receptor pathway. Clin Lung Cancer (2009) 3.37
A biochemically defined system for mammalian nonhomologous DNA end joining. Mol Cell (2004) 3.01
CSF concentration of the anaplastic lymphoma kinase inhibitor crizotinib. J Clin Oncol (2011) 3.00
EGFR exon 20 insertion mutations in non-small-cell lung cancer: preclinical data and clinical implications. Lancet Oncol (2011) 2.47
Combined vascular endothelial growth factor receptor and epidermal growth factor receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance. Clin Cancer Res (2009) 2.04
Effects of erlotinib in EGFR mutated non-small cell lung cancers with resistance to gefitinib. Clin Cancer Res (2008) 2.00
Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance. Cancer Res (2008) 1.95
Pooled analysis of the prospective trials of gefitinib monotherapy for EGFR-mutant non-small cell lung cancers. Lung Cancer (2007) 1.87
XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps. EMBO J (2007) 1.80
Novel PINK1 mutations in early-onset parkinsonism. Ann Neurol (2004) 1.72
Preclinical rationale for use of the clinically available multitargeted tyrosine kinase inhibitor crizotinib in ROS1-translocated lung cancer. J Thorac Oncol (2012) 1.66
Dual specificity phosphatase 6 (DUSP6) is an ETS-regulated negative feedback mediator of oncogenic ERK signaling in lung cancer cells. Carcinogenesis (2010) 1.64
A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia. J Clin Invest (2007) 1.63
Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis. J Biol Chem (2006) 1.61
Differential responses to erlotinib in epidermal growth factor receptor (EGFR)-mutated lung cancers with acquired resistance to gefitinib carrying the L747S or T790M secondary mutations. J Clin Oncol (2008) 1.53
EGFR-mutated lung cancer: a paradigm of molecular oncology. Oncotarget (2010) 1.53
Erlotinib at a dose of 25 mg daily for non-small cell lung cancers with EGFR mutations. J Thorac Oncol (2010) 1.42
Genistein and daidzein, typical soy isoflavones, inhibit TNF-α-mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes. Mol Nutr Food Res (2012) 1.41
Resistance to an irreversible epidermal growth factor receptor (EGFR) inhibitor in EGFR-mutant lung cancer reveals novel treatment strategies. Cancer Res (2007) 1.41
Primary small-cell neuroendocrine carcinoma of the breast: report of a case. Surg Today (2008) 1.39
Structural analysis of isosteviol and related compounds as DNA polymerase and DNA topoisomerase inhibitors. Life Sci (2005) 1.32
DNA repair in plants. Chem Rev (2006) 1.30
Remote asymmetric induction with vinylketene silyl n,o-acetal. J Am Chem Soc (2004) 1.22
Apoptosis induced by JAK2 inhibition is mediated by Bim and enhanced by the BH3 mimetic ABT-737 in JAK2 mutant human erythroid cells. Blood (2010) 1.21
Absence of the transcription factor CCAAT enhancer binding protein alpha results in loss of myeloid identity in bcr/abl-induced malignancy. Proc Natl Acad Sci U S A (2006) 1.20
Prediction of survival with squamous cell carcinoma antigen in patients with resectable esophageal squamous cell carcinoma. Surgery (2003) 1.20
Development of vaccine strains of H5 and H7 influenza viruses. Jpn J Vet Res (2008) 1.18
Synthetic studies on amphidinolide B1. Org Lett (2006) 1.15
Wandering spleen with chronic torsion. Am J Surg (2008) 1.14
A biochemically defined system for coding joint formation in V(D)J recombination. Mol Cell (2008) 1.13
Nonhomologous DNA end joining (NHEJ) and chromosomal translocations in humans. Subcell Biochem (2010) 1.13
A new peptidic ligand and its receptor regulating adrenal function in rats. J Biol Chem (2003) 1.11
A single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS). J Exp Med (2003) 1.11
Frequent detection of K-ras mutation in stool samples of colorectal carcinoma patients after improved DNA extraction: comparison with tissue samples. Int J Oncol (2002) 1.10
Inhibition of transcellular tumor cell migration and metastasis by novel carba-derivatives of cyclic phosphatidic acid. Biochim Biophys Acta (2006) 1.10
Over-expression of human DNA polymerase lambda in E. coli and characterization of the recombinant enzyme. Genes Cells (2002) 1.09
Inhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-kinase (PI3K)/AKT pathways. J Cell Physiol (2012) 1.08
Hemangiopericytoma of the greater omentum. J Gastrointest Surg (2007) 1.08
Identification and characterization of the UL56 gene product of herpes simplex virus type 2. J Virol (2002) 1.06
Importance of preoperative imaging with 64-row three-dimensional multidetector computed tomography for safer video-assisted thoracic surgery in lung cancer. Surg Today (2009) 1.05
A higher plant has three different types of RPA heterotrimeric complex. J Biochem (2006) 1.05
Identification of a neuropeptide modified with bromine as an endogenous ligand for GPR7. J Biol Chem (2002) 1.04
Synergistic induction of antigen-specific CTL by fusions of TLR-stimulated dendritic cells and heat-stressed tumor cells. J Immunol (2007) 1.02
Grb2 and Gads exhibit different interactions with CD28 and play distinct roles in CD28-mediated costimulation. J Immunol (2006) 1.02
Plant DNA polymerase lambda, a DNA repair enzyme that functions in plant meristematic and meiotic tissues. Eur J Biochem (2004) 1.01
A novel DNA polymerase homologous to Escherichia coli DNA polymerase I from a higher plant, rice (Oryza sativa L.). Nucleic Acids Res (2002) 1.01
Drosophila damaged DNA-binding protein 1 is an essential factor for development. Genetics (2004) 1.01
Pulmonary vein analysis using three-dimensional computed tomography angiography for thoracic surgery. Gen Thorac Cardiovasc Surg (2010) 1.01
Molecular basis for the action of a dietary flavonoid revealed by the comprehensive identification of apigenin human targets. Proc Natl Acad Sci U S A (2013) 1.01
Biological functions of a novel lipid mediator, cyclic phosphatidic acid. Biochim Biophys Acta (2002) 1.00
Streptococcal preparation OK-432 promotes fusion efficiency and enhances induction of antigen-specific CTL by fusions of dendritic cells and colorectal cancer cells. J Immunol (2007) 1.00
CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational up-regulation of p42 CCAAT enhancer binding protein alpha. Blood (2007) 1.00
A new antibiotic, antimycin Ag, produced by Streptomyces sp. K01-0031. J Antibiot (Tokyo) (2005) 0.99
Small symptomatic pericardial diverticula treated by video-assisted thoracic surgical resection. Ann Thorac Cardiovasc Surg (2009) 0.99
Steryl glucoside is a lipid mediator in stress-responsive signal transduction. Cell Struct Funct (2002) 0.99
Distribution and roles of X-family DNA polymerases in eukaryotes. Biochimie (2008) 0.99
CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells. Development (2010) 0.99
Fluorescence kinetics in HeLa cells after treatment with cell cycle arrest inducers visualized with Fucci (fluorescent ubiquitination-based cell cycle indicator). Cell Biol Int (2011) 0.98
Functional and structural bases of a cysteine-less mutant as a long-lasting substitute for galectin-1. Glycobiology (2008) 0.97
Plastid DNA polymerases from higher plants, Arabidopsis thaliana. Biochem Biophys Res Commun (2005) 0.97
Successful treatment of advanced gallbladder cancer with an anticancer drug S-1: assessment based on intratumoral gene. Int J Clin Oncol (2008) 0.96
Anomalous pulmonary vein detected using three-dimensional computed tomography in a patient with lung cancer undergoing thoracoscopic lobectomy. Gen Thorac Cardiovasc Surg (2008) 0.96
DNA repair in higher plants; photoreactivation is the major DNA repair pathway in non-proliferating cells while excision repair (nucleotide excision repair and base excision repair) is active in proliferating cells. Nucleic Acids Res (2004) 0.96
Where is the best surgical incision for laparoscopic anterior resection? Hepatogastroenterology (2010) 0.96
DNA polymerase lambda directly binds to proliferating cell nuclear antigen through its confined C-terminal region. Genes Cells (2005) 0.95
DNA polymerase gamma inhibition by vitamin K3 induces mitochondria-mediated cytotoxicity in human cancer cells. Cancer Sci (2008) 0.94
Carbohydrate recognition mechanism of HA70 from Clostridium botulinum deduced from X-ray structures in complexes with sialylated oligosaccharides. FEBS Lett (2012) 0.93
Knockdown of LIM15/DMC1 in the mushroom Coprinus cinereus by double-stranded RNA-mediated gene silencing. Microbiology (2005) 0.93
A plant phytotoxin, solanapyrone A, is an inhibitor of DNA polymerase beta and lambda. J Biol Chem (2001) 0.93
Copy number loss of (src homology 2 domain containing)-transforming protein 2 (SHC2) gene: discordant loss in monozygotic twins and frequent loss in patients with multiple system atrophy. Mol Brain (2011) 0.93
A method for the molecular imprinting of hemoglobin on silica surfaces using silanes. Biomaterials (2005) 0.92
Effects of essential oils from herbal plants and citrus fruits on DNA polymerase inhibitory, cancer cell growth inhibitory, antiallergic, and antioxidant activities. J Agric Food Chem (2012) 0.92
TRF4 is involved in polyadenylation of snRNAs in Drosophila melanogaster. Mol Cell Biol (2008) 0.91
Enhanced laminin-derived peptide AG73-mediated liposomal gene transfer by bubble liposomes and ultrasound. Mol Pharm (2010) 0.91
Characterization of all the subunits of replication factor C from a higher plant, rice (Oryza sativa L.), and their relation to development. Plant Mol Biol (2003) 0.91
Concise total synthesis of (-)-myxalamide A. Angew Chem Int Ed Engl (2012) 0.91
Acquired resistance to the ALK inhibitor crizotinib in the absence of an ALK mutation. J Thorac Oncol (2012) 0.91
Heterocomplex formation by Arp4 and β-actin is involved in the integrity of the Brg1 chromatin remodeling complex. J Cell Sci (2012) 0.91
AMF-26, a novel inhibitor of the Golgi system, targeting ADP-ribosylation factor 1 (Arf1) with potential for cancer therapy. J Biol Chem (2011) 0.91
Mammalian mitotic centromere-associated kinesin (MCAK): a new molecular target of sulfoquinovosylacylglycerols novel antitumor and immunosuppressive agents. FEBS J (2005) 0.90
A low pathogenic H5N2 influenza virus isolated in Taiwan acquired high pathogenicity by consecutive passages in chickens. J Vet Med Sci (2011) 0.90
Purification of Drosophila DNA polymerase zeta by REV1 protein-affinity chromatography. Biochem J (2004) 0.90
Retrospective comparison of non-skin-sparing mastectomy and skin-sparing mastectomy with immediate breast reconstruction. Int J Surg Oncol (2011) 0.89
Cyclic phosphatidic acid inhibits RhoA-mediated autophosphorylation of FAK at Tyr-397 and subsequent tumor-cell invasion. Int J Oncol (2003) 0.89