Published in Eur J Pharmacol on March 21, 2005
The pharmacology of sigma-1 receptors. Pharmacol Ther (2009) 3.12
Pharmacology and therapeutic potential of sigma(1) receptor ligands. Curr Neuropharmacol (2008) 1.55
Purification and characterization of the guinea pig sigma-1 receptor functionally expressed in Escherichia coli. Protein Expr Purif (2006) 1.22
Intrathecal treatment with sigma1 receptor antagonists reduces formalin-induced phosphorylation of NMDA receptor subunit 1 and the second phase of formalin test in mice. Br J Pharmacol (2006) 1.16
Sigma-1 receptor knockout mice display a depressive-like phenotype. Behav Brain Res (2008) 1.09
Sigma-1 receptor chaperones and diseases. Cent Nerv Syst Agents Med Chem (2009) 1.08
Activation of the spinal sigma-1 receptor enhances NMDA-induced pain via PKC- and PKA-dependent phosphorylation of the NR1 subunit in mice. Br J Pharmacol (2008) 1.08
Pharmacological properties of S1RA, a new sigma-1 receptor antagonist that inhibits neuropathic pain and activity-induced spinal sensitization. Br J Pharmacol (2012) 1.07
Late-onset inner retinal dysfunction in mice lacking sigma receptor 1 (σR1). Invest Ophthalmol Vis Sci (2011) 1.03
Ligand-dependent localization and intracellular stability of sigma-1 receptors in CHO-K1 cells. J Mol Signal (2007) 1.01
Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors. Psychopharmacology (Berl) (2009) 0.94
Antinociceptive effects of haloperidol and its metabolites in the formalin test in mice. Psychopharmacology (Berl) (2005) 0.92
Sigma-1 receptor expression in sensory neurons and the effect of painful peripheral nerve injury. Mol Pain (2013) 0.84
Neuroprotective effects of high affinity Σ1 receptor selective compounds. Brain Res (2011) 0.83
Sigma-1 receptor antagonism restores injury-induced decrease of voltage-gated Ca2+ current in sensory neurons. J Pharmacol Exp Ther (2014) 0.83
Role of the Sigma-1 receptor in Amyotrophic Lateral Sclerosis (ALS). J Pharmacol Sci (2015) 0.82
Genetic inactivation and pharmacological blockade of sigma-1 receptors prevent paclitaxel-induced sensory-nerve mitochondrial abnormalities and neuropathic pain in mice. Mol Pain (2014) 0.82
Sigma-1 Receptor Antagonist BD1047 Reduces Allodynia and Spinal ERK Phosphorylation Following Chronic Compression of Dorsal Root Ganglion in Rats. Korean J Physiol Pharmacol (2010) 0.80
Sigma-1 receptor expression in the dorsal root ganglion: Reexamination using a highly specific antibody. Neuroscience (2016) 0.78
Improved expression and purification of sigma 1 receptor fused to maltose binding protein by alteration of linker sequence. Protein Expr Purif (2013) 0.78
Sigma-1 receptor inhibition reverses acute inflammatory hyperalgesia in mice: role of peripheral sigma-1 receptors. Psychopharmacology (Berl) (2014) 0.78
Sigma receptors [σRs]: biology in normal and diseased states. J Recept Signal Transduct Res (2015) 0.78
The Antinociceptive Effect of Sigma-1 Receptor Antagonist, BD1047, in a Capsaicin Induced Headache Model in Rats. Korean J Physiol Pharmacol (2009) 0.78
The selective sigma-1 receptor antagonist E-52862 attenuates neuropathic pain of different aetiology in rats. Sci Rep (2016) 0.76
Hydro-ethanolic leaf extract of Ziziphus abyssinica Hochst Ex A. Rich (Rhamnaceae) exhibits anti-nociceptive effects in murine models. BMC Complement Altern Med (2017) 0.75
Blockade of sigma 1 receptors alleviates sensory signs of diabetic neuropathy in rats. Eur J Pain (2016) 0.75
Sigma-1 Receptor Agonism Promotes Mechanical Allodynia After Priming the Nociceptive System with Capsaicin. Sci Rep (2016) 0.75
Antinociceptive Profile of Levo-tetrahydropalmatine in Acute and Chronic Pain Mice Models: Role of spinal sigma-1 receptor. Sci Rep (2016) 0.75
Validation of simple sequence length polymorphism regions of commonly used mouse strains for marker assisted speed congenics screening. Int J Genomics (2015) 0.75
Effects of a selective sigma 1 antagonist compound on inflammatory pain. Inflammation (2014) 0.75
Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis. Science (2007) 2.70
Genetic polymorphisms among C57BL/6 mouse inbred strains. Transgenic Res (2010) 1.81
Sigma-1 receptors regulate activity-induced spinal sensitization and neuropathic pain after peripheral nerve injury. Pain (2009) 1.75
The potential benefits of insulators on heterologous constructs in transgenic animals. Transgenic Res (2003) 1.70
Generation and phenotypic analysis of sigma receptor type I (sigma 1) knockout mice. Eur J Neurosci (2003) 1.49
Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes. Nat Struct Mol Biol (2011) 1.31
Melanin precursors prevent premature age-related and noise-induced hearing loss in albino mice. Pigment Cell Melanoma Res (2009) 1.11
Dioxin receptor and SLUG transcription factors regulate the insulator activity of B1 SINE retrotransposons via an RNA polymerase switch. Genome Res (2011) 1.10
Phenytoin differentially modulates the affinity of agonist and antagonist ligands for sigma 1 receptors of guinea pig brain. Synapse (2005) 0.98
Irreversible blockade of sigma-1 receptors by haloperidol and its metabolites in guinea pig brain and SH-SY5Y human neuroblastoma cells. J Neurochem (2007) 0.97
Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors. Psychopharmacology (Berl) (2009) 0.94
Boundaries in vertebrate genomes: different solutions to adequately insulate gene expression domains. Brief Funct Genomic Proteomic (2009) 0.93
Antinociceptive effects of haloperidol and its metabolites in the formalin test in mice. Psychopharmacology (Berl) (2005) 0.92
Albinism in Europe. J Dermatol (2013) 0.91
An insulator embedded in the chicken α-globin locus regulates chromatin domain configuration and differential gene expression. Nucleic Acids Res (2010) 0.90
A survey to establish performance standards for the production of transgenic mice. Transgenic Res (2009) 0.89
Pharmacological activation of 5-HT7 receptors reduces nerve injury-induced mechanical and thermal hypersensitivity. Pain (2010) 0.89
A strategy to study tyrosinase transgenes in mouse melanocytes. BMC Cell Biol (2005) 0.88
Effects of serine/threonine protein phosphatase inhibitors on morphine-induced antinociception in the tail flick test in mice. Eur J Pharmacol (2003) 0.88
Generation of yeast artificial chromosome transgenic mice by intracytoplasmic sperm injection. Methods Mol Biol (2006) 0.87
Identification and functional validation of a 5' upstream regulatory sequence in the human tyrosinase gene homologous to the locus control region of the mouse tyrosinase gene. Pigment Cell Res (2003) 0.87
Efficient generation of transgenic mice with intact yeast artificial chromosomes by intracytoplasmic sperm injection. Biol Reprod (2004) 0.86
A transgenic mouse model with inducible Tyrosinase gene expression using the tetracycline (Tet-on) system allows regulated rescue of abnormal chiasmatic projections found in albinism. Pigment Cell Res (2004) 0.85
Ectopic expression of tyrosine hydroxylase in the pigmented epithelium rescues the retinal abnormalities and visual function common in albinos in the absence of melanin. J Neurochem (2006) 0.83
Artificial chromosome transgenesis in pigmentary research. Pigment Cell Res (2002) 0.83
Binary recombinase systems for high-resolution conditional mutagenesis. Nucleic Acids Res (2014) 0.83
Genetic inactivation and pharmacological blockade of sigma-1 receptors prevent paclitaxel-induced sensory-nerve mitochondrial abnormalities and neuropathic pain in mice. Mol Pain (2014) 0.82
Functional dissection of the mouse tyrosinase locus control region identifies a new putative boundary activity. Nucleic Acids Res (2003) 0.82
Tyrosinase gene expression is not detected in mouse brain outside the retinal pigment epithelium cells. Eur J Neurosci (2003) 0.82
A role for insulator elements in the regulation of gene expression response to hypoxia. Nucleic Acids Res (2011) 0.81
Differences in the allosteric modulation by phenytoin of the binding properties of the sigma1 ligands [3H](+)-pentazocine and [3H]NE-100. Synapse (2006) 0.81
Antiallodynic and analgesic effects of maslinic acid, a pentacyclic triterpenoid from Olea europaea. J Nat Prod (2013) 0.81
S1RA, a selective sigma-1 receptor antagonist, inhibits inflammatory pain in the carrageenan and complete Freund's adjuvant models in mice. Behav Pharmacol (2014) 0.80
σ1 receptors are involved in the visceral pain induced by intracolonic administration of capsaicin in mice. Anesthesiology (2013) 0.80
Role of Na(+), K(+)-ATPase in morphine-induced antinociception. J Pharmacol Exp Ther (2003) 0.80
Hormone-induced modifications of the chromatin structure surrounding upstream regulatory regions conserved between the mouse and rabbit whey acidic protein genes. Biochem J (2003) 0.79
Effect of transgene concentration, flanking matrix attachment regions, and RecA-coating on the efficiency of mouse transgenesis mediated by intracytoplasmic sperm injection. Biol Reprod (2006) 0.79
Predicting the antinociceptive efficacy of σ(1) receptor ligands by a novel receptor fluorescence resonance energy transfer (FRET) based biosensor. J Med Chem (2013) 0.79
Molecular basis of the extreme dilution mottled mouse mutation: a combination of coding and noncoding genomic alterations. J Biol Chem (2004) 0.78
Improving the generation of genomic-type transgenic mice by ICSI. Transgenic Res (2007) 0.78
The antinociceptive effect of morphine is reversed by okadaic acid in morphine-naive but not in morphine-tolerant mice. Pharmacol Biochem Behav (2006) 0.77
Sigma-1 receptor and inflammatory pain. Inflamm Res (2015) 0.77
Regional abnormalities in retinal development are associated with local ocular hypopigmentation. J Comp Neurol (2005) 0.76
Changes in morphine-induced activation of cerebral Na(+),K(+)-ATPase during morphine tolerance: biochemical and behavioral consequences. Biochem Pharmacol (2012) 0.75
Intracytoplasmic sperm injection (ICSI)-mediated transgenesis in mice. Methods Mol Biol (2014) 0.75
On the use of regulatory regions from pigmentary genes to drive the expression of transgenes in mice. Pigment Cell Res (2004) 0.75
Compartir: a Spanish academic network initiative for sharing genetically modified mice. Transgenic Res (2009) 0.75
Analysis of the efficiency of the rabbit whey acidic protein gene 5' flanking region in controlling the expression of homologous and heterologous linked genes. J Dairy Res (2005) 0.75
Meeting report: UC Davis Transgenic Animal Research Conference VI : Granlibakken Conference Center, Tahoe City, California, August 12-16, 2007. Transgenic Res (2007) 0.75
Sigma-1 receptors do not regulate calcium influx through voltage-dependent calcium channels in mouse brain synaptosomes. Eur J Pharmacol (2011) 0.75