Published in Oncogene on June 02, 2005
Caspase cleavage of HER-2 releases a Bad-like cell death effector. J Biol Chem (2008) 0.92
A multi-factor model for caspase degradome prediction. BMC Genomics (2009) 0.83
HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors. Cancer Cell (2006) 3.73
The juxtamembrane region of the EGF receptor functions as an activation domain. Mol Cell (2009) 2.90
ErbB receptors: new insights on mechanisms and biology. Trends Cell Biol (2006) 2.39
Epidermal growth factor receptor juxtamembrane region regulates allosteric tyrosine kinase activation. Proc Natl Acad Sci U S A (2007) 2.20
Role of the Sec61 translocon in EGF receptor trafficking to the nucleus and gene expression. Mol Biol Cell (2007) 1.99
Absence of erythrogenesis and vasculogenesis in Plcg1-deficient mice. J Biol Chem (2001) 1.56
The role of protease activity in ErbB biology. Exp Cell Res (2008) 1.20
Identification of ErbB-2 kinase domain motifs required for geldanamycin-induced degradation. Cancer Res (2003) 1.19
Cetuximab/C225-induced intracellular trafficking of epidermal growth factor receptor. Cancer Res (2009) 1.19
Ectodomain cleavage of ErbB-4: characterization of the cleavage site and m80 fragment. J Biol Chem (2003) 1.17
Role of the ErbB-4 carboxyl terminus in gamma-secretase cleavage. J Biol Chem (2002) 1.15
ErbB-4 s80 intracellular domain abrogates ETO2-dependent transcriptional repression. J Biol Chem (2006) 1.05
EGF-dependent association of phospholipase C-gamma1 with c-Cbl. Exp Cell Res (2002) 1.04
Secretase-dependent tyrosine phosphorylation of Mdm2 by the ErbB-4 intracellular domain fragment. J Biol Chem (2005) 1.00
Integrin-dependent PLC-gamma1 phosphorylation mediates fibronectin-dependent adhesion. J Cell Sci (2005) 0.98
Ligand-induced, p38-dependent apoptosis in cells expressing high levels of epidermal growth factor receptor and ErbB-2. J Biol Chem (2004) 0.92
Bax activation and translocation to mitochondria mediate EGF-induced programmed cell death. J Cell Sci (2005) 0.90
ErbB-4 and TNF-alpha converting enzyme localization to membrane microdomains. Biochem Biophys Res Commun (2006) 0.90
Regulated intramembrane cleavage of the EGF receptor. Traffic (2012) 0.81
PLC-gamma1 is required for IGF-I protection from cell death induced by loss of extracellular matrix adhesion. J Cell Sci (2002) 0.78
Contrasting role of phospholipase C-gamma1 in the expression of immediate early genes induced by epidermal or platelet-derived growth factors. Exp Cell Res (2006) 0.78