Published in Blood on March 22, 2005
Genetic modifiers of sickle cell disease. Am J Hematol (2012) 1.66
Sickle cell leg ulcers: associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway. Br J Haematol (2006) 1.51
Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study. Am J Hematol (2010) 1.34
Genome-wide association studies and the genetic dissection of complex traits. Am J Hematol (2009) 1.04
The search for genetic modifiers of disease severity in the β-hemoglobinopathies. Cold Spring Harb Perspect Med (2012) 0.99
Genetic association studies in osteonecrosis of the femoral head: mini review of the literature. Skeletal Radiol (2008) 0.97
Sickle Cell Disease in the Post Genomic Era: A Monogenic Disease with a Polygenic Phenotype. Genomics Insights (2009) 0.96
The annexin A2/S100A10 system in health and disease: emerging paradigms. J Biomed Biotechnol (2012) 0.96
Minireview: Genetic basis of heterogeneity and severity in sickle cell disease. Exp Biol Med (Maywood) (2016) 0.94
Erythrocytapheresis: Do Not Forget a Useful Therapy! Transfus Med Hemother (2008) 0.92
Annexin A2 system in human biology: cell surface and beyond. Semin Thromb Hemost (2013) 0.92
Bone vascularization in normal and disease conditions. Front Endocrinol (Lausanne) (2013) 0.91
Osteonecrosis of the femoral head in patients with type 1 human immunodeficiency virus infection: clinical analysis and review. Clin Rheumatol (2009) 0.85
High-density SNP genotyping to define beta-globin locus haplotypes. Blood Cells Mol Dis (2008) 0.84
Klotho: its various functions and association with sickle cell disease subphenotypes. Rev Bras Hematol Hemoter (2014) 0.84
Genomic approaches to identifying targets for treating β hemoglobinopathies. BMC Med Genomics (2015) 0.83
Histological and elemental analyses of impaired bone mineralization in klotho-deficient mice. J Anat (2008) 0.82
The Biology of Annexin A2: From Vascular Fibrinolysis to Innate Immunity. Trans Am Clin Climatol Assoc (2015) 0.80
Intravascular hemolysis and the pathophysiology of sickle cell disease. J Clin Invest (2017) 0.78
Klotho locus, metabolic traits, and serum hemoglobin in hospitalized older patients: a genetic association analysis. Age (Dordr) (2011) 0.78
Osteonecrosis in genetic disorders. Clin Cases Miner Bone Metab (2007) 0.76
Microarchitectural and mechanical characterization of the sickle bone. J Mech Behav Biomed Mater (2015) 0.75
Avascular necrosis in pediatric systemic lupus erythematosus: a brief report and review of the literature. Pediatr Rheumatol Online J (2015) 0.75
Bone morphogenetic protein 6 polymorphisms are associated with radiographic progression in ankylosing spondylitis. PLoS One (2014) 0.75
Klotho gene polymorphisms and their association with sickle cell disease phenotypes. Rev Bras Hematol Hemoter (2015) 0.75
Musculoskeletal Manifestations of Sickle Cell Disease: A Review. Cureus (2015) 0.75
Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (2004) 125.23
A new statistical method for haplotype reconstruction from population data. Am J Hum Genet (2001) 59.30
A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet (2003) 26.59
SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol Pharmacol (2002) 8.89
Genetic dissection and prognostic modeling of overt stroke in sickle cell anemia. Nat Genet (2005) 4.21
Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542. Mol Pharmacol (2002) 3.36
Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system. Mol Endocrinol (2003) 3.15
Osteonecrosis of the hip: management in the 21st century. Instr Course Lect (2003) 2.42
Identification of novel inhibitors of the transforming growth factor beta1 (TGF-beta1) type 1 receptor (ALK5). J Med Chem (2002) 1.94
Recruitment in the Cooperative Study of Sickle Cell Disease (CSSCD). Control Clin Trials (1987) 1.93
Sickle cell disease as a cause of osteonecrosis of the femoral head. N Engl J Med (1991) 1.86
The cooperative study of sickle cell disease: review of study design and objectives. Am J Pediatr Hematol Oncol (1982) 1.85
Activation of bone morphogenetic protein/Smad signaling in bronchial epithelial cells during airway inflammation. Am J Respir Cell Mol Biol (2002) 1.45
Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases. Cell Mol Life Sci (2000) 1.42
Association of single nucleotide polymorphisms in klotho with priapism in sickle cell anaemia. Br J Haematol (2005) 1.26
The role of annexin 2 in osteoblastic mineralization. J Cell Sci (2003) 1.19
The role of BMP-6, IL-6, and BMP-4 in mesenchymal stem cell-dependent bone development: effects on osteoblastic differentiation induced by parathyroid hormone and vitamin D(3). Stem Cells Dev (2004) 1.17
Osteonecrosis of the humeral head in sickle cell disease. Clin Orthop Relat Res (1993) 1.04
cDNA microarray analysis of changes in gene expression induced by neuronal hypoxia in vitro. Neurochem Res (2002) 1.00
Ectopic osteogenesis using adenoviral bone morphogenetic protein (BMP)-4 and BMP-6 gene transfer. Mol Ther (2002) 0.99
Regulation of stanniocalcin 1 and 2 expression in the kidney by klotho gene. Biochem Biophys Res Commun (2003) 0.89
Implementing syndromic surveillance: a practical guide informed by the early experience. J Am Med Inform Assoc (2003) 6.75
Disentangling the roles of disability and morbidity in survival to exceptional old age. Arch Intern Med (2008) 4.77
Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer. Nat Med (2007) 4.63
Deconstructing sickle cell disease: reappraisal of the role of hemolysis in the development of clinical subphenotypes. Blood Rev (2006) 4.46
Retracted Genetic signatures of exceptional longevity in humans. Science (2010) 4.33
Genetic dissection and prognostic modeling of overt stroke in sickle cell anemia. Nat Genet (2005) 4.21
Cluster analysis of gene expression dynamics. Proc Natl Acad Sci U S A (2002) 3.83
Genetic signatures of exceptional longevity in humans. PLoS One (2012) 3.20
Diagnostic reliability of the Semi-structured Assessment for Drug Dependence and Alcoholism (SSADDA). Drug Alcohol Depend (2005) 3.09
Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms. Nature (2004) 2.98
BET bromodomain inhibition as a novel strategy for reactivation of HIV-1. J Leukoc Biol (2012) 2.80
Prospective medical assessment of adults surviving childhood cancer: study design, cohort characteristics, and feasibility of the St. Jude Lifetime Cohort study. Pediatr Blood Cancer (2010) 2.69
Meta-analysis of 13 genome scans reveals multiple cleft lip/palate genes with novel loci on 9q21 and 2q32-35. Am J Hum Genet (2004) 2.65
Depression as a risk factor for Alzheimer disease: the MIRAGE Study. Arch Neurol (2003) 2.56
Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster. Blood (2009) 2.50
Fetal hemoglobin in sickle cell anemia. Blood (2011) 2.44
A network model to predict the risk of death in sickle cell disease. Blood (2007) 2.39
Imputation of missing genotypes: an empirical evaluation of IMPUTE. BMC Genet (2008) 2.34
Health span approximates life span among many supercentenarians: compression of morbidity at the approximate limit of life span. J Gerontol A Biol Sci Med Sci (2012) 2.30
Reliability of DSM-IV diagnostic criteria using the semi-structured assessment for drug dependence and alcoholism (SSADDA). Drug Alcohol Depend (2007) 2.26
Genomewide linkage scan for cocaine dependence and related traits: significant linkages for a cocaine-related trait and cocaine-induced paranoia. Am J Med Genet B Neuropsychiatr Genet (2005) 2.24
An official American Thoracic Society clinical practice guideline: diagnosis, risk stratification, and management of pulmonary hypertension of sickle cell disease. Am J Respir Crit Care Med (2014) 2.23
The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort. Arch Neurol (2007) 2.21
The Cenozoic palaeoenvironment of the Arctic Ocean. Nature (2006) 2.21
Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression. Genome Biol (2007) 2.20
Fetal hemoglobin in sickle cell anemia: a glass half full? Blood (2013) 2.19
Genomewide linkage scan for opioid dependence and related traits. Am J Hum Genet (2006) 2.15
Vasculopathy in sickle cell disease: Biology, pathophysiology, genetics, translational medicine, and new research directions. Am J Hematol (2009) 2.05
N-terminal pro-brain natriuretic peptide levels and risk of death in sickle cell disease. JAMA (2006) 2.04
Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations. Arch Gen Psychiatry (2009) 1.97
Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations. Hum Mol Genet (2006) 1.94
Alcohol consumption by women before and during pregnancy. Matern Child Health J (2008) 1.94
Hemolysis-associated priapism in sickle cell disease. Blood (2005) 1.86
The AED (antiepileptic drug) pregnancy registry: a 6-year experience. Arch Neurol (2004) 1.82
The paradox of hemoglobin SC disease. Blood Rev (2003) 1.75
Chronic hyper-hemolysis in sickle cell anemia: association of vascular complications and mortality with less frequent vasoocclusive pain. PLoS One (2008) 1.75
Health and function of participants in the Long Life Family Study: A comparison with other cohorts. Aging (Albany NY) (2011) 1.74
A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment. Am J Respir Crit Care Med (2013) 1.73
Genetic modifiers of sickle cell disease. Am J Hematol (2012) 1.66
Sickle cell disease in Saudi Arabia: the phenotype in adults with the Arab-Indian haplotype is not benign. Br J Haematol (2013) 1.63
Fetal hemoglobin in sickle cell anemia: genetic studies of the Arab-Indian haplotype. Blood Cells Mol Dis (2013) 1.54
Sickle cell anemia is associated with reduced nitric oxide bioactivity in peripheral conduit and resistance vessels. Am J Hematol (2003) 1.53
Sickle cell leg ulcers: associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway. Br J Haematol (2006) 1.51
Abnormal pulmonary function in adults with sickle cell anemia. Am J Respir Crit Care Med (2006) 1.50
Expression of microRNA and their gene targets are dysregulated in preinvasive breast cancer. Breast Cancer Res (2011) 1.49
A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression. Blood (2011) 1.47
A content analysis of e-mail communication between primary care providers and parents. Pediatrics (2005) 1.45
Determining the cause of patchwork HBA1 and HBA2 genes: recurrent gene conversion or crossing over fixation events. Haematologica (2006) 1.45
The association between hydroxyurea treatment and pain intensity, analgesic use, and utilization in ambulatory sickle cell anemia patients. Pain Med (2011) 1.45
Similarities and differences between smoking-related gene expression in nasal and bronchial epithelium. Physiol Genomics (2009) 1.42
A prediction model for lung cancer diagnosis that integrates genomic and clinical features. Cancer Prev Res (Phila) (2008) 1.41
Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study. Am J Hematol (2010) 1.34
Retraction. Science (2011) 1.32
BCL11A represses HBG transcription in K562 cells. Blood Cells Mol Dis (2009) 1.32
The validity of cocaine dependence subtypes. Addict Behav (2007) 1.28
Pulmonary hypertension and NO in sickle cell. Blood (2010) 1.28
Association of longer telomeres with better health in centenarians. J Gerontol A Biol Sci Med Sci (2008) 1.28
Adverse childhood events as risk factors for substance dependence: partial mediation by mood and anxiety disorders. Addict Behav (2009) 1.27
The cyclophosphamide equivalent dose as an approach for quantifying alkylating agent exposure: a report from the Childhood Cancer Survivor Study. Pediatr Blood Cancer (2013) 1.27
Unexpectedly low pulse oximetry measurements associated with variant hemoglobins: a systematic review. Am J Hematol (2010) 1.26
Association of single nucleotide polymorphisms in klotho with priapism in sickle cell anaemia. Br J Haematol (2005) 1.26
Fetal hemoglobin in sickle cell anemia: molecular characterization of the unusually high fetal hemoglobin phenotype in African Americans. Am J Hematol (2011) 1.26
Centenarian offspring: start healthier and stay healthier. J Am Geriatr Soc (2008) 1.26
Pulmonary arterial hypertension and left-sided heart disease in sickle cell disease: clinical characteristics and association with soluble adhesion molecule expression. Am J Hematol (2008) 1.25
Genomewide linkage scan for nicotine dependence: identification of a chromosome 5 risk locus. Biol Psychiatry (2006) 1.23
Guidelines for the design and analysis of studies on nonsyndromic cleft lip and cleft palate in humans: summary report from a Workshop of the International Consortium for Oral Clefts Genetics. Cleft Palate Craniofac J (2002) 1.23
Variation and heritability of Hb F and F-cells among beta-thalassemia heterozygotes in Hong Kong. Am J Hematol (2008) 1.22
Bayesian methods for multivariate modeling of pleiotropic SNP associations and genetic risk prediction. Front Genet (2012) 1.19
Characteristics of 32 supercentenarians. J Am Geriatr Soc (2006) 1.19
Teratogenicity of sodium valproate. Expert Opin Drug Saf (2005) 1.19
Erythrocyte glutamine depletion, altered redox environment, and pulmonary hypertension in sickle cell disease. Blood (2007) 1.17
Hospitalization rates among survivors of childhood cancer in the Childhood Cancer Survivor Study cohort. Pediatr Blood Cancer (2011) 1.16
RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans. PLoS One (2009) 1.16
APOE genotype and MRI markers of cerebrovascular disease: systematic review and meta-analysis. Neurology (2013) 1.14
Bayesian approaches to reverse engineer cellular systems: a simulation study on nonlinear Gaussian networks. BMC Bioinformatics (2007) 1.14
Fetal hemoglobin in sickle cell anemia: Saudi patients from the Southwestern province have similar HBB haplotypes but higher HbF levels than African Americans. Am J Hematol (2011) 1.14
Clustering by genetic ancestry using genome-wide SNP data. BMC Genet (2010) 1.12
Physical performance limitations among adult survivors of childhood brain tumors. Cancer (2010) 1.12
Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans. Blood (2012) 1.12