Minute virus of mice small non-structural protein NS2 localizes within, but is not required for the formation of, Smn-associated autonomous parvovirus-associated replication bodies.

Parvovirus induced alterations in nuclear architecture and dynamics. PLoS One (2009) 0.93

Replication initiator protein NS1 of the parvovirus minute virus of mice binds to modular divergent sites distributed throughout duplex viral DNA. J Virol (2007) 0.93

Recruitment of DNA replication and damage response proteins to viral replication centers during infection with NS2 mutants of Minute Virus of Mice (MVM). Virology (2010) 0.91

An in-frame deletion in the NS protein-coding sequence of parvovirus H-1PV efficiently stimulates export and infectivity of progeny virions. J Virol (2012) 0.82

Mosquito densonucleosis virus non-structural protein NS2 is necessary for a productive infection. Virology (2008) 0.81

Distribution and dynamics of transcription-associated proteins during parvovirus infection. J Virol (2012) 0.76

Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature (2008) 12.21

Pharmaceutical Cocrystals and Their Physicochemical Properties. Cryst Growth Des (2009) 2.77

Transfection of mammalian cells using linear polyethylenimine is a simple and effective means of producing recombinant adeno-associated virus vectors. J Virol Methods (2006) 2.36

The family Parvoviridae. Arch Virol (2013) 2.12

Combination of SMN trans-splicing and a neurotrophic factor increases the life span and body mass in a severe model of spinal muscular atrophy. Hum Gene Ther (2010) 1.93

Cardiac defects contribute to the pathology of spinal muscular atrophy models. Hum Mol Genet (2010) 1.76

A non-sequence-specific requirement for SMN protein activity: the role of aminoglycosides in inducing elevated SMN protein levels. Hum Mol Genet (2005) 1.72

Deaminase-independent inhibition of parvoviruses by the APOBEC3A cytidine deaminase. PLoS Pathog (2009) 1.65

Characterization of the transcription profile of adeno-associated virus type 5 reveals a number of unique features compared to previously characterized adeno-associated viruses. J Virol (2002) 1.64

SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1. Hum Mol Genet (2002) 1.53

Delivery of bifunctional RNAs that target an intronic repressor and increase SMN levels in an animal model of spinal muscular atrophy. Hum Mol Genet (2009) 1.53

The adeno-associated virus type 2 Rep protein regulates RNA processing via interaction with the transcription template. Mol Cell Biol (2002) 1.51

Development of a single vector system that enhances trans-splicing of SMN2 transcripts. PLoS One (2008) 1.43

The transcription profile of Aleutian mink disease virus in CRFK cells is generated by alternative processing of pre-mRNAs produced from a single promoter. J Virol (2006) 1.41

Restoration of SMN function: delivery of a trans-splicing RNA re-directs SMN2 pre-mRNA splicing. Mol Ther (2007) 1.39

Stimulating full-length SMN2 expression by delivering bifunctional RNAs via a viral vector. Mol Ther (2006) 1.37

Protein phosphatase 1 binds to the RNA recognition motif of several splicing factors and regulates alternative pre-mRNA processing. Hum Mol Genet (2007) 1.33

Delivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophy. Hum Mol Genet (2008) 1.32

Trans-splicing-mediated improvement in a severe mouse model of spinal muscular atrophy. J Neurosci (2010) 1.32

Novel aminoglycosides increase SMN levels in spinal muscular atrophy fibroblasts. Hum Genet (2006) 1.31

Block to the production of full-length B19 virus transcripts by internal polyadenylation is overcome by replication of the viral genome. J Virol (2008) 1.26

Interaction between parvovirus NS2 protein and nuclear export factor Crm1 is important for viral egress from the nucleus of murine cells. J Virol (2002) 1.24

Spinal muscular atrophy: a motor neuron disorder or a multi-organ disease? J Anat (2013) 1.23

Comparison of the transcription profile of simian parvovirus with that of the human erythrovirus B19 reveals a number of unique features. J Virol (2004) 1.21

A direct interaction between the survival motor neuron protein and p53 and its relationship to spinal muscular atrophy. J Biol Chem (2001) 1.20

Delivery of a read-through inducing compound, TC007, lessens the severity of a spinal muscular atrophy animal model. Hum Mol Genet (2009) 1.19

Trans-splicing adeno-associated viral vector-mediated gene therapy is limited by the accumulation of spliced mRNA but not by dual vector coinfection efficiency. Hum Gene Ther (2004) 1.16

Effect of diet on the survival and phenotype of a mouse model for spinal muscular atrophy. Biochem Biophys Res Commun (2009) 1.14

A negatively acting bifunctional RNA increases survival motor neuron both in vitro and in vivo. Hum Gene Ther (2008) 1.13

Alternative polyadenylation of adeno-associated virus type 5 RNA within an internal intron is governed by the distance between the promoter and the intron and is inhibited by U1 small nuclear RNP binding to the intervening donor. J Biol Chem (2004) 1.12

Minute virus of mice NS1 interacts with the SMN protein, and they colocalize in novel nuclear bodies induced by parvovirus infection. J Virol (2002) 1.08

Alternative polyadenylation of adeno-associated virus type 5 RNA within an internal intron is governed by both a downstream element within the intron 3' splice acceptor and an element upstream of the P41 initiation site. J Virol (2004) 1.08

The COPI vesicle complex binds and moves with survival motor neuron within axons. Hum Mol Genet (2011) 1.08

Bifunctional RNAs targeting the intronic splicing silencer N1 increase SMN levels and reduce disease severity in an animal model of spinal muscular atrophy. Mol Ther (2011) 1.07

Induction of full-length survival motor neuron by polyphenol botanical compounds. Hum Genet (2007) 1.06

Analysis of amorphous and nanocrystalline solids from their X-ray diffraction patterns. Pharm Res (2006) 1.05

Chromatin-modifying proteins in cancer. APMIS (2007) 1.04

Delivery of therapeutic agents through intracerebroventricular (ICV) and intravenous (IV) injection in mice. J Vis Exp (2011) 1.03

Parvovirus minute virus of mice induces a DNA damage response that facilitates viral replication. PLoS Pathog (2010) 1.03

Cationic liposomes containing mycobacterial lipids: a new powerful Th1 adjuvant system. Infect Immun (2005) 1.03

Quantitation of encapsidated recombinant adeno-associated virus DNA in crude cell lysates and tissue culture medium by quantitative, real-time PCR. J Virol Methods (2006) 1.01

Direct central nervous system delivery provides enhanced protection following vector mediated gene replacement in a severe model of spinal muscular atrophy. Biochem Biophys Res Commun (2011) 1.01

Identification and characterization of two internal cleavage and polyadenylation sites of parvovirus B19 RNA. J Virol (2006) 1.00

RNA-targeting approaches for neuromuscular diseases. Trends Mol Med (2009) 0.97

A SMNDelta7 read-through product confers functionality to the SMNDelta7 protein. Neurosci Lett (2008) 0.97

Positive and negative effects of adenovirus type 5 helper functions on adeno-associated virus type 5 (AAV5) protein accumulation govern AAV5 virus production. J Virol (2006) 0.97

Human circovirus TT virus genotype 6 expresses six proteins following transfection of a full-length clone. J Virol (2005) 0.96

The choice of translation initiation site of the rep proteins from goose parvovirus P9-generated mRNA is governed by splicing and the nature of the excised intron. J Virol (2009) 0.95

E4Orf6-E1B-55k-dependent degradation of de novo-generated adeno-associated virus type 5 Rep52 and capsid proteins employs a cullin 5-containing E3 ligase complex. J Virol (2008) 0.95

Expression profiles of bovine adeno-associated virus and avian adeno-associated virus display significant similarity to that of adeno-associated virus type 5. J Virol (2006) 0.94

SMN in spinal muscular atrophy and snRNP biogenesis. Wiley Interdiscip Rev RNA (2011) 0.93

Decreasing disease severity in symptomatic, Smn(-/-);SMN2(+/+), spinal muscular atrophy mice following scAAV9-SMN delivery. Hum Gene Ther (2012) 0.92

The Ewing's sarcoma protein interacts with the Tudor domain of the survival motor neuron protein. Brain Res Mol Brain Res (2003) 0.92

The Wallerian degeneration slow (Wld(s)) gene does not attenuate disease in a mouse model of spinal muscular atrophy. Biochem Biophys Res Commun (2008) 0.92

Efficient expression of the adeno-associated virus type 5 p41 capsid gene promoter in 293 cells does not require Rep. J Virol (2006) 0.92

Characterization of the nonstructural proteins of the bocavirus minute virus of canines. J Virol (2012) 0.92

Loss of miR-10a activates lpo and collaborates with activated Wnt signaling in inducing intestinal neoplasia in female mice. PLoS Genet (2013) 0.91

Partial restoration of cardio-vascular defects in a rescued severe model of spinal muscular atrophy. J Mol Cell Cardiol (2012) 0.91

SMN-inducing compounds for the treatment of spinal muscular atrophy. Future Med Chem (2012) 0.90

Disruption of the Survival Motor Neuron (SMN) gene in pigs using ssDNA. Transgenic Res (2011) 0.87

Development and characterization of an SMN2-based intermediate mouse model of Spinal Muscular Atrophy. Hum Mol Genet (2013) 0.87

Transgenic inactivation of murine myostatin does not decrease the severity of disease in a model of Spinal Muscular Atrophy. Neuromuscul Disord (2011) 0.87

Detection of human survival motor neuron (SMN) protein in mice containing the SMN2 transgene: applicability to preclinical therapy development for spinal muscular atrophy. J Neurosci Methods (2008) 0.87

Adeno-associated viruses can induce phosphorylation of eIF2alpha via PKR activation, which can be overcome by helper adenovirus type 5 virus-associated RNA. J Virol (2007) 0.87

Minute virus of mice small nonstructural protein NS2 interacts and colocalizes with the Smn protein. J Virol (2002) 0.86

Therapeutics that directly increase SMN expression to treat spinal muscular atrophy. Drug News Perspect (2010) 0.86

The spinal muscular atrophy mouse model, SMAΔ7, displays altered axonal transport without global neurofilament alterations. Acta Neuropathol (2011) 0.86

Adeno-associated virus small rep proteins are modified with at least two types of polyubiquitination. J Virol (2009) 0.85

Subcutaneous administration of TC007 reduces disease severity in an animal model of SMA. BMC Neurosci (2009) 0.85

RNAse mapping and quantitation of RNA isoforms. Methods Mol Biol (2012) 0.84

Enhancement of SMN protein levels in a mouse model of spinal muscular atrophy using novel drug-like compounds. EMBO Mol Med (2013) 0.84

Identification of a tripartite import signal in the Ewing Sarcoma protein (EWS). Biochem Biophys Res Commun (2009) 0.83

Survival motor neuron protein in the nucleolus of mammalian neurons. Brain Res (2002) 0.81

Optimization of SMN trans-splicing through the analysis of SMN introns. J Mol Neurosci (2011) 0.81

Molecular characterization of three newly recognized rat parvoviruses. J Gen Virol (2002) 0.81

A survival motor neuron:tetanus toxin fragment C fusion protein for the targeted delivery of SMN protein to neurons. Brain Res (2004) 0.80

Adeno-associated virus type 5 utilizes alternative translation initiation to encode a small Rep40-like protein. J Virol (2009) 0.80

Improved splicing of adeno-associated viral (AAV) capsid protein-supplying pre-mRNAs leads to increased recombinant AAV vector production. Hum Gene Ther (2008) 0.80

Identification of a self-association domain in the Ewing's sarcoma protein: a novel function for arginine-glycine-glycine rich motifs? J Biochem (2010) 0.80

Replacement of huntingtin exon 1 by trans-splicing. Cell Mol Life Sci (2012) 0.80

Replication of minute virus of mice in murine cells is facilitated by virally induced depletion of p21. J Virol (2012) 0.80

Upstream AP1- and CREB-binding sites confer high basal activity on the adeno-associated virus type 5 capsid gene promoter. J Virol (2007) 0.79

Identification and characterization of the porcine (Sus scrofa) survival motor neuron (SMN1) gene: an animal model for therapeutic studies. Dev Dyn (2008) 0.79

Analysis of a read-through promoting compound in a severe mouse model of spinal muscular atrophy. Neurosci Lett (2012) 0.79

The adeno-associated virus type 5 small rep proteins expressed via internal translation initiation are functional. J Virol (2012) 0.78

Monitoring of recombinant survival motor neuron protein using fiber-optic surface plasmon resonance. Analyst (2004) 0.78

Splicing of goose parvovirus pre-mRNA influences cytoplasmic translation of the processed mRNA. Virology (2012) 0.77

PRDM11 is dispensable for the maintenance and function of hematopoietic stem and progenitor cells. Stem Cell Res (2013) 0.77

Restoration of SMN to Emx-1 expressing cortical neurons is not sufficient to provide benefit to a severe mouse model of Spinal Muscular Atrophy. Transgenic Res (2013) 0.76

Identification and characterisation of a nuclear localisation signal in the SMN associated protein, Gemin4. Biochem Biophys Res Commun (2008) 0.75

The transcription strategy of bovine adeno-associated virus (B-AAV) combines features of both adeno-associated virus type 2 (AAV2) and type 5 (AAV5). Virology (2007) 0.75

Interview with Ann Newman, APRN, DSN, CNE candidate for NC House of Representatives. Tar Heel Nurse (2010) 0.75

A solid-state approach to enable early development compounds: selection and animal bioavailability studies of an itraconazole amorphous solid dispersion. J Pharm Sci (2010) 0.75