PubRank

Robert M Sapolsky

Author PubWeight™ 86.10‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice. Cell 2005 4.25
2 Behavioral changes induced by Toxoplasma infection of rodents are highly specific to aversion of cat odors. Proc Natl Acad Sci U S A 2007 2.84
3 Akt contributes to neuroprotection by hypothermia against cerebral ischemia in rats. J Neurosci 2005 2.53
4 Interrupting reperfusion as a stroke therapy: ischemic postconditioning reduces infarct size after focal ischemia in rats. J Cereb Blood Flow Metab 2006 2.41
5 Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicol Appl Pharmacol 2007 2.37
6 An inflammatory review of glucocorticoid actions in the CNS. Brain Behav Immun 2006 2.31
7 The influence of stress hormones on fear circuitry. Annu Rev Neurosci 2009 2.25
8 Phosphoinositide-3-kinase/akt survival signal pathways are implicated in neuronal survival after stroke. Mol Neurobiol 2006 2.17
9 Acute corticosterone treatment is sufficient to induce anxiety and amygdaloid dendritic hypertrophy. Proc Natl Acad Sci U S A 2008 1.75
10 Sleep restriction suppresses neurogenesis induced by hippocampus-dependent learning. J Neurophysiol 2005 1.72
11 Bcl-2 overexpression protects against neuron loss within the ischemic margin following experimental stroke and inhibits cytochrome c translocation and caspase-3 activity. J Neurochem 2003 1.69
12 The stressed CNS: when glucocorticoids aggravate inflammation. Neuron 2009 1.66
13 General versus specific actions of mild-moderate hypothermia in attenuating cerebral ischemic damage. J Cereb Blood Flow Metab 2007 1.57
14 Chronic unpredictable stress exacerbates lipopolysaccharide-induced activation of nuclear factor-kappaB in the frontal cortex and hippocampus via glucocorticoid secretion. J Neurosci 2006 1.55
15 Early postnatal handling alters glucocorticoid receptor concentrations in selected brain regions. Behav Neurosci 2013 1.53
16 Support for religio-political aggression among teenaged boys in Gaza: part II: neuroendocrinological findings. Aggress Behav 2010 1.41
17 Stress and depression: possible links to neuron death in the hippocampus. Bipolar Disord 2002 1.38
18 Bcl-2 transfection via herpes simplex virus blocks apoptosis-inducing factor translocation after focal ischemia in the rat. J Cereb Blood Flow Metab 2004 1.36
19 Novel glucocorticoid effects on acute inflammation in the CNS. J Neurochem 2003 1.33
20 Structural consequences of Kcna1 gene deletion and transfer in the mouse hippocampus. Epilepsia 2007 1.19
21 Glucocorticoids exacerbate lipopolysaccharide-induced signaling in the frontal cortex and hippocampus in a dose-dependent manner. J Neurosci 2010 1.18
22 Changes in brain MicroRNAs contribute to cholinergic stress reactions. J Mol Neurosci 2009 1.16
23 Neurotoxic effects of polymorphonuclear granulocytes on hippocampal primary cultures. Proc Natl Acad Sci U S A 2003 1.13
24 Gene transfer of HSP72 protects cornu ammonis 1 region of the hippocampus neurons from global ischemia: influence of Bcl-2. Ann Neurol 2002 1.12
25 Biphasic cytochrome c release after transient global ischemia and its inhibition by hypothermia. J Cereb Blood Flow Metab 2005 1.12
26 Treponema pallidum infection in the wild baboons of East Africa: distribution and genetic characterization of the strains responsible. PLoS One 2012 1.12
27 Mothering style and methylation. Nat Neurosci 2004 1.05
28 Conditions of protection by hypothermia and effects on apoptotic pathways in a rat model of permanent middle cerebral artery occlusion. J Neurosurg 2007 1.03
29 Serum leptin levels as a marker for a syndrome X-like condition in wild baboons. J Clin Endocrinol Metab 2003 1.03
30 Effects of food availability on serum insulin and lipid concentrations in free-ranging baboons. Am J Primatol 2002 1.01
31 Glucocorticoids influence brain glycogen levels during sleep deprivation. Am J Physiol Regul Integr Comp Physiol 2004 0.99
32 Mild postischemic hypothermia prolongs the time window for gene therapy by inhibiting cytochrome C release. Stroke 2004 0.97
33 Hypothermia blocks beta-catenin degradation after focal ischemia in rats. Brain Res 2008 0.96
34 Sleep deprivation effects on growth factor expression in neonatal rats: a potential role for BDNF in the mediation of delta power. J Neurophysiol 2003 0.95
35 Chickens, eggs and hippocampal atrophy. Nat Neurosci 2002 0.95
36 Mineralocorticoid receptor overexpression in basolateral amygdala reduces corticosterone secretion and anxiety. Biol Psychiatry 2009 0.93
37 The exacerbation of hippocampal excitotoxicity by glucocorticoids is not mediated by apoptosis. Neuroendocrinology 2003 0.91
38 Prokineticin 2 is an endangering mediator of cerebral ischemic injury. Proc Natl Acad Sci U S A 2012 0.90
39 Glucocorticoid signaling in myeloid cells worsens acute CNS injury and inflammation. J Neurosci 2013 0.89
40 Catalase over-expression protects striatal neurons from transient focal cerebral ischemia. Neuroreport 2004 0.89
41 Potassium channel gene therapy can prevent neuron death resulting from necrotic and apoptotic insults. J Neurochem 2003 0.89
42 Gene therapy using SOD1 protects striatal neurons from experimental stroke. Neurosci Lett 2006 0.87
43 Disruption of fear memory through dual-hormone gene therapy. Biol Psychiatry 2008 0.87
44 Characterization of monocyte chemoattractant protein-1 expression following a kainate model of status epilepticus. Brain Res 2007 0.87
45 Dual-gene, dual-cell type therapy against an excitotoxic insult by bolstering neuroenergetics. J Neurosci 2004 0.86
46 Male orangutan subadulthood: a new twist on the relationship between chronic stress and developmental arrest. Am J Phys Anthropol 2002 0.85
47 Anti-glucocorticoid gene therapy reverses the impairing effects of elevated corticosterone on spatial memory, hippocampal neuronal excitability, and synaptic plasticity. J Neurosci 2010 0.85
48 Soluble TNF receptor 1-secreting ex vivo-derived dendritic cells reduce injury after stroke. J Cereb Blood Flow Metab 2013 0.84
49 Gene therapy and hypothermia for stroke treatment. Ann N Y Acad Sci 2003 0.84
50 Anti-apoptotic therapy with a Tat fusion protein protects against excitotoxic insults in vitro and in vivo. Exp Neurol 2007 0.83
51 Glucocorticoid exacerbation of gp120 neurotoxicity: role of microglia. Exp Neurol 2002 0.83
52 Akt isoforms differentially protect against stroke-induced neuronal injury by regulating mTOR activities. J Cereb Blood Flow Metab 2013 0.82
53 Evidence for caspase effects on release of cytochrome c and AIF in a model of ischemia in cortical neurons. Neurosci Lett 2009 0.82
54 The microtubule interacting drug candidate NAP protects against kainic acid toxicity in a rat model of epilepsy. J Neurochem 2009 0.82
55 Expression of chimeric estrogen-glucocorticoid-receptor in the amygdala reduces anxiety. Brain Res 2010 0.81
56 Effects of enrichment predominate over those of chronic stress on fear-related behavior in male rats. Stress 2009 0.81
57 Blocking glucocorticoid and enhancing estrogenic genomic signaling protects against cerebral ischemia. J Cereb Blood Flow Metab 2008 0.80
58 Effects of glucocorticoids in the gp120-induced inhibition of glutamate uptake in hippocampal cultures. Brain Res 2003 0.80
59 Protection against gp120-induced neurotoxicity by an array of estrogenic steroids. Brain Res 2002 0.80
60 Support for religio-political aggression among teenaged boys in Gaza: Part I: psychological findings. Aggress Behav 2010 0.80
61 Neighbor effects of neurons bearing protective transgenes. Brain Res 2010 0.80
62 Gene therapy in rodent amygdala against fear disorders. Expert Opin Biol Ther 2010 0.79
63 Derivation of injury-responsive dendritic cells for acute brain targeting and therapeutic protein delivery in the stroke-injured rat. PLoS One 2013 0.79
64 Physiologic manifestations of stress from capture and restraint of free-ranging male African green monkeys (Cercopithecus aethiops). J Zoo Wildl Med 2004 0.79
65 Effects of overexpression of antioxidants on the release of cytochrome c and apoptosis-inducing factor in the model of ischemia. Neurosci Lett 2009 0.79
66 Glucocorticoids and central nervous system inflammation. J Neurovirol 2002 0.79
67 The neuroprotective effects of virally-derived caspase inhibitors p35 and crmA following a necrotic insult. Neurobiol Dis 2003 0.79
68 Glucocorticoids can arm macrophages for innate immune battle. Brain Behav Immun 2009 0.78
69 Short-term enrichment makes male rats more attractive, more defensive and alters hypothalamic neurons. PLoS One 2012 0.78
70 Glucocorticoids increase excitotoxic injury and inflammation in the hippocampus of adult male rats. Neuroendocrinology 2014 0.78
71 Gene therapy in neurological disease. Methods Mol Med 2005 0.77
72 gp120 neurotoxicity fails to induce heat shock defenses, while the over expression of hsp70 protects against gp120. Brain Res Bull 2003 0.77
73 Effect of GP120 on glutathione peroxidase activity in cortical cultures and the interaction with steroid hormones. J Neurochem 2002 0.77
74 An insult-inducible vector system activated by hypoxia and oxidative stress for neuronal gene therapy. Transl Stroke Res 2011 0.76
75 Disturbing behaviors of the orangutan. Sci Am 2002 0.75
76 Prospects for the treatment of stroke using gene therapy. Expert Rev Neurother 2003 0.75