Published in J Neurosci on April 05, 2006
An inflammatory review of glucocorticoid actions in the CNS. Brain Behav Immun (2006) 2.31
Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior. Proc Natl Acad Sci U S A (2010) 2.17
Understanding the somatic consequences of depression: biological mechanisms and the role of depression symptom profile. BMC Med (2013) 1.78
Stress-induced recruitment of bone marrow-derived monocytes to the brain promotes anxiety-like behavior. J Neurosci (2013) 1.73
Unravelling the pathophysiology of delirium: a focus on the role of aberrant stress responses. J Psychosom Res (2008) 1.72
The stressed CNS: when glucocorticoids aggravate inflammation. Neuron (2009) 1.66
Glucocorticoids exacerbate lipopolysaccharide-induced signaling in the frontal cortex and hippocampus in a dose-dependent manner. J Neurosci (2010) 1.18
Dysregulated neuronal-microglial cross-talk during aging, stress and inflammation. Exp Neurol (2010) 1.12
At the extreme end of the psychoneuroimmunological spectrum: delirium as a maladaptive sickness behaviour response. Brain Behav Immun (2012) 1.11
Repeated lipopolysaccharide (LPS) or cytokine treatments sensitize ethanol withdrawal-induced anxiety-like behavior. Neuropsychopharmacology (2007) 1.08
Surveillance, phagocytosis, and inflammation: how never-resting microglia influence adult hippocampal neurogenesis. Neural Plast (2014) 1.07
The HPA - Immune Axis and the Immunomodulatory Actions of Glucocorticoids in the Brain. Front Immunol (2014) 1.02
Exacerbation of CNS inflammation and neurodegeneration by systemic LPS treatment is independent of circulating IL-1β and IL-6. J Neuroinflammation (2011) 1.01
Chronic exposure to exogenous glucocorticoids primes microglia to pro-inflammatory stimuli and induces NLRP3 mRNA in the hippocampus. Psychoneuroendocrinology (2013) 0.99
Chronic exposure to corticosterone enhances the neuroinflammatory and neurotoxic responses to methamphetamine. J Neurochem (2012) 0.98
Stress induces the danger-associated molecular pattern HMGB-1 in the hippocampus of male Sprague Dawley rats: a priming stimulus of microglia and the NLRP3 inflammasome. J Neurosci (2015) 0.97
Prior exposure to glucocorticoids potentiates lipopolysaccharide induced mechanical allodynia and spinal neuroinflammation. Brain Behav Immun (2011) 0.96
Neuroinflammation in the normal aging hippocampus. Neuroscience (2015) 0.95
Cognitive dysfunction with aging and the role of inflammation. Ther Adv Chronic Dis (2011) 0.92
Blocking toll-like receptor 2 and 4 signaling during a stressor prevents stress-induced priming of neuroinflammatory responses to a subsequent immune challenge. Brain Behav Immun (2013) 0.91
Chronic intermittent cold stress sensitizes neuro-immune reactivity in the rat brain. Psychoneuroendocrinology (2011) 0.90
Time-dependent effects of training on cardiovascular control in spontaneously hypertensive rats: role for brain oxidative stress and inflammation and baroreflex sensitivity. PLoS One (2014) 0.90
Glucocorticoid signaling in myeloid cells worsens acute CNS injury and inflammation. J Neurosci (2013) 0.89
Intermittent fasting attenuates lipopolysaccharide-induced neuroinflammation and memory impairment. J Neuroinflammation (2014) 0.89
The characteristic long-term upregulation of hippocampal NF-κB complex in PTSD-like behavioral stress response is normalized by high-dose corticosterone and pyrrolidine dithiocarbamate administered immediately after exposure. Neuropsychopharmacology (2011) 0.88
Stress sounds the alarmin: The role of the danger-associated molecular pattern HMGB1 in stress-induced neuroinflammatory priming. Brain Behav Immun (2015) 0.87
Glucocorticoids regulate natural killer cell function epigenetically. Cell Immunol (2014) 0.87
Cocaine induces cell death and activates the transcription nuclear factor kappa-B in PC12 cells. Mol Brain (2009) 0.86
Alcohol extract of Echinacea pallida reverses stress-delayed wound healing in mice. Phytomedicine (2009) 0.86
Prior laparotomy or corticosterone potentiates lipopolysaccharide-induced fever and sickness behaviors. J Neuroimmunol (2011) 0.85
Neuroimmune mechanisms of alcohol and drug addiction. Int Rev Neurobiol (2014) 0.84
Age-related neuroinflammation and changes in AKT-GSK-3β and WNT/ β-CATENIN signaling in rat hippocampus. Aging (Albany NY) (2015) 0.83
Antiinflammatory treatment ameliorates HPA stress axis dysfunction in a mouse model of stress sensitivity. Endocrinology (2012) 0.82
Mind and body: how the health of the body impacts on neuropsychiatry. Front Pharmacol (2013) 0.82
Glucocorticoid exposure alters the pathogenesis of Theiler's murine encephalomyelitis virus during acute infection. Physiol Behav (2008) 0.82
Relevance of chronic stress and the two faces of microglia in Parkinson's disease. Front Cell Neurosci (2015) 0.81
Dexamethasone exacerbates cerebral edema and brain injury following lithium-pilocarpine induced status epilepticus. Neurobiol Dis (2013) 0.81
Microglia Priming with Aging and Stress. Neuropsychopharmacology (2016) 0.80
Potent and multiple regulatory actions of microglial glucocorticoid receptors during CNS inflammation. Cell Death Differ (2013) 0.80
Gestational exposure to variable stressors produces decrements in cognitive and neural development of juvenile male and female rats. Curr Top Med Chem (2011) 0.80
Greater glucocorticoid receptor activation in hippocampus of aged rats sensitizes microglia. Neurobiol Aging (2014) 0.80
Microglial cells are involved in the susceptibility of NADPH oxidase knockout mice to 6-hydroxy-dopamine-induced neurodegeneration. PLoS One (2013) 0.80
Inflammation and lithium: clues to mechanisms contributing to suicide-linked traits. Transl Psychiatry (2014) 0.80
Glucocorticoid receptors: finding the middle ground. J Clin Invest (2017) 0.79
Sex differences in the neuro-immune consequences of stress: Focus on depression and anxiety. Brain Behav Immun (2017) 0.79
Signaling function of Na,K-ATPase induced by ouabain against LPS as an inflammation model in hippocampus. J Neuroinflammation (2014) 0.78
Glucocorticoids increase excitotoxic injury and inflammation in the hippocampus of adult male rats. Neuroendocrinology (2014) 0.78
Glucocorticoids can arm macrophages for innate immune battle. Brain Behav Immun (2009) 0.78
Altered KLOTHO and NF-κB-TNF-α Signaling Are Correlated with Nephrectomy-Induced Cognitive Impairment in Rats. PLoS One (2015) 0.78
Glucocorticoids Mediate Short-Term High-Fat Diet Induction of Neuroinflammatory Priming, the NLRP3 Inflammasome, and the Danger Signal HMGB1. eNeuro (2016) 0.77
Role of Glia in Stress-Induced Enhancement and Impairment of Memory. Front Integr Neurosci (2016) 0.77
Stress-induced neuroinflammation is mediated by GSK3-dependent TLR4 signaling that promotes susceptibility to depression-like behavior. Brain Behav Immun (2016) 0.77
Stress-induced neuroinflammatory priming: A liability factor in the etiology of psychiatric disorders. Neurobiol Stress (2015) 0.76
Glucocorticoid-Potentiated Spinal Microglia Activation Contributes to Preoperative Anxiety-Induced Postoperative Hyperalgesia. Mol Neurobiol (2016) 0.76
Stress exacerbates neuron loss and microglia proliferation in a rat model of excitotoxic lower motor neuron injury. Brain Behav Immun (2015) 0.76
An Integrated Review of Psychological Stress in Parkinson's Disease: Biological Mechanisms and Symptom and Health Outcomes. Parkinsons Dis (2016) 0.76
A pre-conditioning stress accelerates increases in mouse plasma inflammatory cytokines induced by stress. BMC Neurosci (2015) 0.76
Antidepressant-Like Effect of Lipid Extract of Channa striatus in Chronic Unpredictable Mild Stress Model of Depression in Rats. Evid Based Complement Alternat Med (2016) 0.75
The Immunomodulatory Effects of Plant Extracts and Plant Secondary Metabolites on Chronic Neuroinflammation and Cognitive Aging: A Mechanistic and Empirical Review. Front Pharmacol (2017) 0.75
Low-dose lipopolysaccharide (LPS) inhibits aggressive and augments depressive behaviours in a chronic mild stress model in mice. J Neuroinflammation (2016) 0.75
Influence of the dopaminergic system, CREB, and transcription factor-κB on cocaine neurotoxicity. Braz J Med Biol Res (2013) 0.75
The Role of Steroid Hormones in the Modulation of Neuroinflammation by Dietary Interventions. Front Endocrinol (Lausanne) (2016) 0.75
The Pro-inflammatory Effects of Glucocorticoids in the Brain. Front Endocrinol (Lausanne) (2016) 0.75
Effects of aging on stress-related responses of serotonergic neurons in the dorsal raphe nucleus of male rats. Neurobiol Stress (2016) 0.75
Chronic unpredictable stress exacerbates surgery-induced sickness behavior and neuroinflammatory responses via glucocorticoids secretion in adult rats. PLoS One (2017) 0.75
Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice. Cell (2005) 4.25
Behavioral changes induced by Toxoplasma infection of rodents are highly specific to aversion of cat odors. Proc Natl Acad Sci U S A (2007) 2.84
Akt contributes to neuroprotection by hypothermia against cerebral ischemia in rats. J Neurosci (2005) 2.53
Interrupting reperfusion as a stroke therapy: ischemic postconditioning reduces infarct size after focal ischemia in rats. J Cereb Blood Flow Metab (2006) 2.41
Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicol Appl Pharmacol (2007) 2.37
An inflammatory review of glucocorticoid actions in the CNS. Brain Behav Immun (2006) 2.31
The influence of stress hormones on fear circuitry. Annu Rev Neurosci (2009) 2.25
Phosphoinositide-3-kinase/akt survival signal pathways are implicated in neuronal survival after stroke. Mol Neurobiol (2006) 2.17
Acute corticosterone treatment is sufficient to induce anxiety and amygdaloid dendritic hypertrophy. Proc Natl Acad Sci U S A (2008) 1.75
Sleep restriction suppresses neurogenesis induced by hippocampus-dependent learning. J Neurophysiol (2005) 1.72
Bcl-2 overexpression protects against neuron loss within the ischemic margin following experimental stroke and inhibits cytochrome c translocation and caspase-3 activity. J Neurochem (2003) 1.69
The stressed CNS: when glucocorticoids aggravate inflammation. Neuron (2009) 1.66
General versus specific actions of mild-moderate hypothermia in attenuating cerebral ischemic damage. J Cereb Blood Flow Metab (2007) 1.57
Early postnatal handling alters glucocorticoid receptor concentrations in selected brain regions. Behav Neurosci (2013) 1.53
Support for religio-political aggression among teenaged boys in Gaza: part II: neuroendocrinological findings. Aggress Behav (2010) 1.41
Stress and depression: possible links to neuron death in the hippocampus. Bipolar Disord (2002) 1.38
Bcl-2 transfection via herpes simplex virus blocks apoptosis-inducing factor translocation after focal ischemia in the rat. J Cereb Blood Flow Metab (2004) 1.36
Novel glucocorticoid effects on acute inflammation in the CNS. J Neurochem (2003) 1.33
Intrauterine undernutrition: expression and activity of the endothelial nitric oxide synthase in male and female adult offspring. Cardiovasc Res (2002) 1.20
Structural consequences of Kcna1 gene deletion and transfer in the mouse hippocampus. Epilepsia (2007) 1.19
Glucocorticoids exacerbate lipopolysaccharide-induced signaling in the frontal cortex and hippocampus in a dose-dependent manner. J Neurosci (2010) 1.18
Changes in brain MicroRNAs contribute to cholinergic stress reactions. J Mol Neurosci (2009) 1.16
Neurotoxic effects of polymorphonuclear granulocytes on hippocampal primary cultures. Proc Natl Acad Sci U S A (2003) 1.13
Gene transfer of HSP72 protects cornu ammonis 1 region of the hippocampus neurons from global ischemia: influence of Bcl-2. Ann Neurol (2002) 1.12
Biphasic cytochrome c release after transient global ischemia and its inhibition by hypothermia. J Cereb Blood Flow Metab (2005) 1.12
Treponema pallidum infection in the wild baboons of East Africa: distribution and genetic characterization of the strains responsible. PLoS One (2012) 1.12
Leishmania (L.) amazonensis-induced inhibition of nitric oxide synthesis in host macrophages. Microbes Infect (2002) 1.10
Enhanced oxidative stress as a potential mechanism underlying the programming of hypertension in utero. J Cardiovasc Pharmacol (2002) 1.09
Mothering style and methylation. Nat Neurosci (2004) 1.05
Conditions of protection by hypothermia and effects on apoptotic pathways in a rat model of permanent middle cerebral artery occlusion. J Neurosurg (2007) 1.03
Serum leptin levels as a marker for a syndrome X-like condition in wild baboons. J Clin Endocrinol Metab (2003) 1.03
Effects of food availability on serum insulin and lipid concentrations in free-ranging baboons. Am J Primatol (2002) 1.01
Glucocorticoids influence brain glycogen levels during sleep deprivation. Am J Physiol Regul Integr Comp Physiol (2004) 0.99
Mild postischemic hypothermia prolongs the time window for gene therapy by inhibiting cytochrome C release. Stroke (2004) 0.97
Hypothermia blocks beta-catenin degradation after focal ischemia in rats. Brain Res (2008) 0.96
Chickens, eggs and hippocampal atrophy. Nat Neurosci (2002) 0.95
Sleep deprivation effects on growth factor expression in neonatal rats: a potential role for BDNF in the mediation of delta power. J Neurophysiol (2003) 0.95
MK-801 and 7-Ni attenuate the activation of brain NF-kappa B induced by LPS. Neuropharmacology (2003) 0.93
Mineralocorticoid receptor overexpression in basolateral amygdala reduces corticosterone secretion and anxiety. Biol Psychiatry (2009) 0.93
Parthenolide reduces cisplatin-induced renal damage. Toxicology (2006) 0.92
Oxidative state in platelets and erythrocytes in aging and Alzheimer's disease. Neurobiol Aging (2005) 0.92
The exacerbation of hippocampal excitotoxicity by glucocorticoids is not mediated by apoptosis. Neuroendocrinology (2003) 0.91
Prokineticin 2 is an endangering mediator of cerebral ischemic injury. Proc Natl Acad Sci U S A (2012) 0.90
Catalase over-expression protects striatal neurons from transient focal cerebral ischemia. Neuroreport (2004) 0.89
Glucocorticoid signaling in myeloid cells worsens acute CNS injury and inflammation. J Neurosci (2013) 0.89
Potassium channel gene therapy can prevent neuron death resulting from necrotic and apoptotic insults. J Neurochem (2003) 0.89
Changes in vascular reactivity following administration of isoproterenol for 1 week: a role for endothelial modulation. Br J Pharmacol (2006) 0.88
Repeated predictable or unpredictable stress: effects on cocaine-induced locomotion and cyclic AMP-dependent protein kinase activity. Behav Brain Res (2003) 0.88
Environmental modulation of ethanol-induced locomotor activity: Correlation with neuronal activity in distinct brain regions of adolescent and adult Swiss mice. Brain Res (2008) 0.88
Correction of endothelial dysfunction in diabetic female rats by tetrahydrobiopterin and chronic insulin. J Vasc Res (2006) 0.88
Gene therapy using SOD1 protects striatal neurons from experimental stroke. Neurosci Lett (2006) 0.87
Characterization of monocyte chemoattractant protein-1 expression following a kainate model of status epilepticus. Brain Res (2007) 0.87
Disruption of fear memory through dual-hormone gene therapy. Biol Psychiatry (2008) 0.87
Dual-gene, dual-cell type therapy against an excitotoxic insult by bolstering neuroenergetics. J Neurosci (2004) 0.86
Modulation of the innate immune response by NMDA receptors has neuropathological consequences. J Neurosci (2003) 0.86
Cocaine induces cell death and activates the transcription nuclear factor kappa-B in PC12 cells. Mol Brain (2009) 0.86
Male orangutan subadulthood: a new twist on the relationship between chronic stress and developmental arrest. Am J Phys Anthropol (2002) 0.85
Anti-glucocorticoid gene therapy reverses the impairing effects of elevated corticosterone on spatial memory, hippocampal neuronal excitability, and synaptic plasticity. J Neurosci (2010) 0.85
Soluble TNF receptor 1-secreting ex vivo-derived dendritic cells reduce injury after stroke. J Cereb Blood Flow Metab (2013) 0.84
Effects of isoproterenol treatment for 7 days on inflammatory mediators in the rat aorta. Am J Physiol Heart Circ Physiol (2008) 0.84
Gene therapy and hypothermia for stroke treatment. Ann N Y Acad Sci (2003) 0.84
Melatonin synthesis impairment as a new deleterious outcome of diabetes-derived hyperglycemia. J Pineal Res (2014) 0.83
Age-related changes in cyclic GMP and PKG-stimulated cerebellar Na,K-ATPase activity. Neurobiol Aging (2005) 0.83
Anti-apoptotic therapy with a Tat fusion protein protects against excitotoxic insults in vitro and in vivo. Exp Neurol (2007) 0.83
Glucocorticoid exacerbation of gp120 neurotoxicity: role of microglia. Exp Neurol (2002) 0.83
Mechanisms of the anti-inflammatory effects of the natural secosteroids physalins in a model of intestinal ischaemia and reperfusion injury. Br J Pharmacol (2005) 0.82
Evidence for caspase effects on release of cytochrome c and AIF in a model of ischemia in cortical neurons. Neurosci Lett (2009) 0.82
Tetrahydrobiopterin improves endothelial dysfunction and vascular oxidative stress in microvessels of intrauterine undernourished rats. J Physiol (2004) 0.82
The microtubule interacting drug candidate NAP protects against kainic acid toxicity in a rat model of epilepsy. J Neurochem (2009) 0.82
Akt isoforms differentially protect against stroke-induced neuronal injury by regulating mTOR activities. J Cereb Blood Flow Metab (2013) 0.82
Biomarkers of oxidative stress and antioxidant status in children born small for gestational age: evidence of lipid peroxidation. Pediatr Res (2007) 0.82
Effects of enrichment predominate over those of chronic stress on fear-related behavior in male rats. Stress (2009) 0.81
Expression of chimeric estrogen-glucocorticoid-receptor in the amygdala reduces anxiety. Brain Res (2010) 0.81
Blocking glucocorticoid and enhancing estrogenic genomic signaling protects against cerebral ischemia. J Cereb Blood Flow Metab (2008) 0.80
Effects of glucocorticoids in the gp120-induced inhibition of glutamate uptake in hippocampal cultures. Brain Res (2003) 0.80
Support for religio-political aggression among teenaged boys in Gaza: Part I: psychological findings. Aggress Behav (2010) 0.80
Glutamate modulates sodium-potassium-ATPase through cyclic GMP and cyclic GMP-dependent protein kinase in rat striatum. Cell Biochem Funct (2005) 0.80
Role of vascular Kinin B1 and B2 receptors in endothelial nitric oxide metabolism. Peptides (2011) 0.80
Microglial cells are involved in the susceptibility of NADPH oxidase knockout mice to 6-hydroxy-dopamine-induced neurodegeneration. PLoS One (2013) 0.80
Protection against gp120-induced neurotoxicity by an array of estrogenic steroids. Brain Res (2002) 0.80
The role of Wnt signaling and its interaction with diverse mechanisms of cellular apoptosis in the pathophysiology of bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry (2010) 0.80
Neighbor effects of neurons bearing protective transgenes. Brain Res (2010) 0.80
Effects of overexpression of antioxidants on the release of cytochrome c and apoptosis-inducing factor in the model of ischemia. Neurosci Lett (2009) 0.79
Glucocorticoids and central nervous system inflammation. J Neurovirol (2002) 0.79
Derivation of injury-responsive dendritic cells for acute brain targeting and therapeutic protein delivery in the stroke-injured rat. PLoS One (2013) 0.79
Gene therapy in rodent amygdala against fear disorders. Expert Opin Biol Ther (2010) 0.79
Fatty acid control of nitric oxide production by macrophages. FEBS Lett (2006) 0.79
Physiologic manifestations of stress from capture and restraint of free-ranging male African green monkeys (Cercopithecus aethiops). J Zoo Wildl Med (2004) 0.79
The neuroprotective effects of virally-derived caspase inhibitors p35 and crmA following a necrotic insult. Neurobiol Dis (2003) 0.79
Apolipoprotein E genotype is related to nitric oxide production in platelets. Cell Biochem Funct (2008) 0.79
Changes in sodium, potassium-ATPase induced by repeated fencamfamine: the roles of cyclic AMP-dependent protein kinase and the nitric oxide-cyclic GMP pathway. Neuropharmacology (2003) 0.78
Age-related changes in cerebellar phosphatase-1 reduce Na,K-ATPase activity. Neurobiol Aging (2007) 0.78