Published in Anticancer Res on April 08, 2005
ABL-N-induced apoptosis in human breast cancer cells is partially mediated by c-Jun NH2-terminal kinase activation. Breast Cancer Res (2010) 0.84
Selective cytotoxicity, inhibition of cell cycle progression, and induction of apoptosis in human breast cancer cells by sesquiterpenoids from Inula lineariifolia Turcz. Eur J Med Chem (2013) 0.80
Celecoxib and acetylbritannilactone interact synergistically to suppress breast cancer cell growth via COX-2-dependent and -independent mechanisms. Cell Death Dis (2011) 0.80
Antiaging Effect of Inula britannica on Aging Mouse Model Induced by D-Galactose. Evid Based Complement Alternat Med (2016) 0.77
Inulae Flos and Its Compounds Inhibit TNF-α- and IFN-γ-Induced Chemokine Production in HaCaT Human Keratinocytes. Evid Based Complement Alternat Med (2012) 0.75
1,6-O,O-Diacetylbritannilactone Inhibits Eotaxin-1 and ALOX15 Expression Through Inactivation of STAT6 in A549 Cells. Inflammation (2017) 0.75
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell (2006) 11.79
Role of autophagy in cancer. Nat Rev Cancer (2007) 10.88
Autophagy suppresses tumorigenesis through elimination of p62. Cell (2009) 9.95
Autophagy and metabolism. Science (2010) 8.10
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes Dev (2011) 7.43
Autophagy suppresses tumor progression by limiting chromosomal instability. Genes Dev (2007) 7.41
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. Genes Dev (2007) 6.35
The transcriptional repressor Snail promotes mammary tumor recurrence. Cancer Cell (2005) 5.81
Principles and current strategies for targeting autophagy for cancer treatment. Clin Cancer Res (2011) 5.40
DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells. Genes Dev (2003) 3.67
Role of autophagy in cancer: management of metabolic stress. Autophagy (2007) 3.40
Ammonia derived from glutaminolysis is a diffusible regulator of autophagy. Sci Signal (2010) 3.38
Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy. Cancer Cell (2005) 3.19
Bax and Bak independently promote cytochrome C release from mitochondria. J Biol Chem (2002) 3.18
A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62. Mol Cell Biol (2010) 2.93
CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression. J Clin Invest (2011) 2.90
Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis. Genes Dev (2013) 2.90
Contemporary risk profile of prostate cancer in the United States. J Natl Cancer Inst (2009) 2.85
Hypoxia and defective apoptosis drive genomic instability and tumorigenesis. Genes Dev (2004) 2.69
BAX and BAK mediate p53-independent suppression of tumorigenesis. Cancer Cell (2002) 2.64
Metabolic catastrophe as a means to cancer cell death. J Cell Sci (2007) 2.58
Viral homologs of BCL-2: role of apoptosis in the regulation of virus infection. Genes Dev (2002) 2.29
The role for autophagy in cancer. J Clin Invest (2015) 2.11
Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night. Curr Opin Genet Dev (2011) 2.09
Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors. Cancer Discov (2013) 2.08
Autophagy-mediated tumor promotion. Cell (2013) 2.08
Prospective, multicenter, randomized phase II trial of the herbal supplement, PC-SPES, and diethylstilbestrol in patients with androgen-independent prostate cancer. J Clin Oncol (2004) 2.02
ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL. EMBO J (2007) 1.90
Association of Bax and Bak homo-oligomers in mitochondria. Bax requirement for Bak reorganization and cytochrome c release. J Biol Chem (2002) 1.82
Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria. Nat Cell Biol (2010) 1.76
A mouse model system to genetically dissect the molecular mechanisms regulating tumorigenesis. Clin Cancer Res (2006) 1.74
Tumor suppression by autophagy through the management of metabolic stress. Autophagy (2008) 1.71
Prostate-specific antigen progression predicts overall survival in patients with metastatic prostate cancer: data from Southwest Oncology Group Trials 9346 (Intergroup Study 0162) and 9916. J Clin Oncol (2009) 1.67
Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia. Mol Syst Biol (2013) 1.56
BH3-only proteins in control: specificity regulates MCL-1 and BAK-mediated apoptosis. Genes Dev (2005) 1.55
NBK/BIK antagonizes MCL-1 and BCL-XL and activates BAK-mediated apoptosis in response to protein synthesis inhibition. Genes Dev (2007) 1.53
Exploiting different ways to die. Genes Dev (2004) 1.51
Caspase-dependent processing activates the proapoptotic activity of deleted in breast cancer-1 during tumor necrosis factor-alpha-mediated death signaling. Oncogene (2005) 1.51
Immortalized mouse epithelial cell models to study the role of apoptosis in cancer. Methods Enzymol (2008) 1.47
Therapeutic starvation and autophagy in prostate cancer: a new paradigm for targeting metabolism in cancer therapy. Prostate (2008) 1.45
Targeting tumor metabolism with 2-deoxyglucose in patients with castrate-resistant prostate cancer and advanced malignancies. Prostate (2010) 1.45
Role of autophagy in cancer prevention. Cancer Prev Res (Phila) (2011) 1.43
A phase I dose-escalation trial of 2-deoxy-D-glucose alone or combined with docetaxel in patients with advanced solid tumors. Cancer Chemother Pharmacol (2012) 1.41
Role of autophagy in breast cancer. Autophagy (2007) 1.39
Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition. PLoS One (2012) 1.37
ASAP, a novel protein complex involved in RNA processing and apoptosis. Mol Cell Biol (2003) 1.34
Why sick cells produce tumors: the protective role of autophagy. Autophagy (2007) 1.34
Adult cancer survivors discuss follow-up in primary care: 'not what i want, but maybe what i need'. Ann Fam Med (2012) 1.33
Autophagy opposes p53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2-associated hereditary breast cancer. Cancer Discov (2013) 1.32
Role of the polarity determinant crumbs in suppressing mammalian epithelial tumor progression. Cancer Res (2008) 1.30
Nutlin-3 protects kidney cells during cisplatin therapy by suppressing Bax/Bak activation. J Biol Chem (2006) 1.30
Deleted in breast cancer 1, a novel androgen receptor (AR) coactivator that promotes AR DNA-binding activity. J Biol Chem (2009) 1.30
Bak and Bax function to limit adenovirus replication through apoptosis induction. J Virol (2002) 1.24
Abiraterone in prostate cancer: a new angle to an old problem. Clin Cancer Res (2012) 1.21
Autophagic cell death unraveled: Pharmacological inhibition of apoptosis and autophagy enables necrosis. Autophagy (2008) 1.14
Mutational landscape of the essential autophagy gene BECN1 in human cancers. Mol Cancer Res (2014) 1.13
Characterization of flavonols in cranberry (Vaccinium macrocarpon) powder. J Agric Food Chem (2004) 1.13
Liquid chromatography-high resolution mass spectrometry analysis of fatty acid metabolism. Anal Chem (2011) 1.13
Production of membrane proteins for NMR studies using the condensed single protein (cSPP) production system. J Struct Funct Genomics (2009) 1.12
Immunohistochemical detection of cytoplasmic LC3 puncta in human cancer specimens. Autophagy (2012) 1.12
Assessing metabolic stress and autophagy status in epithelial tumors. Methods Enzymol (2009) 1.11
Arsenic inhibits autophagic flux, activating the Nrf2-Keap1 pathway in a p62-dependent manner. Mol Cell Biol (2013) 1.10
Effect of dual inhibition of apoptosis and autophagy in prostate cancer. Prostate (2012) 1.07
A mouse mammary epithelial cell model to identify molecular mechanisms regulating breast cancer progression. Methods Enzymol (2008) 1.05
Measurement of subcellular texture by optical Gabor-like filtering with a digital micromirror device. Opt Lett (2008) 1.04
Antioxidative phenolic compounds isolated from almond skins (Prunus amygdalus Batsch). J Agric Food Chem (2002) 1.04
Induction of apoptosis by diterpenes from the soft coral Xenia elongata. J Nat Prod (2007) 1.03
Bcl-2 modulation to activate apoptosis in prostate cancer. Mol Cancer Res (2009) 1.01
E1A sensitizes cells to tumor necrosis factor alpha by downregulating c-FLIP S. J Virol (2003) 1.01
Akt-dependent expression of NAIP-1 protects neurons against amyloid-{beta} toxicity. J Biol Chem (2005) 0.98
Inhibitory Effect of a γ-Tocopherol-Rich Mixture of Tocopherols on the Formation and Growth of LNCaP Prostate Tumors in Immunodeficient Mice. Cancers (Basel) (2011) 0.97
Autophagy regulates keratin 8 homeostasis in mammary epithelial cells and in breast tumors. Mol Cancer Res (2010) 0.96
Cilengitide (EMD 121974, NSC 707544) in asymptomatic metastatic castration resistant prostate cancer patients: a randomized phase II trial by the prostate cancer clinical trials consortium. Invest New Drugs (2010) 0.95
Novel polyphenol molecule isolated from licorice root (Glycrrhiza glabra) induces apoptosis, G2/M cell cycle arrest, and Bcl-2 phosphorylation in tumor cell lines. J Agric Food Chem (2002) 0.93
Regulation of the mitochondrial checkpoint in p53-mediated apoptosis confers resistance to cell death. Oncogene (2002) 0.92
Use of hormonal therapy in men with metastatic prostate cancer. J Urol (2006) 0.92
Bone directed therapies for prostate cancer. J Urol (2007) 0.91
Therapeutic targeting of death pathways in cancer: mechanisms for activating cell death in cancer cells. Adv Exp Med Biol (2008) 0.91
Enzymatic synthesis of tea theaflavin derivatives and their anti-inflammatory and cytotoxic activities. Bioorg Med Chem (2004) 0.91
Does control of mutant p53 by Mdm2 complicate cancer therapy? Genes Dev (2008) 0.90
Obesity and prostate cancer detection: insights from three national surveys. Am J Med (2010) 0.89
Chemical studies of the antioxidant mechanism of tea catechins: radical reaction products of epicatechin with peroxyl radicals. Bioorg Med Chem (2003) 0.89
Epothilone induced cytotoxicity is dependent on p53 status in prostate cells. Prostate (2004) 0.89
Defective ubiquitin-mediated degradation of antiapoptotic Bfl-1 predisposes to lymphoma. Blood (2010) 0.89
A novel proteomic coculture model of prostate cancer cell growth. Proteomics (2004) 0.89
Epidemiology of Cigarette and Smokeless Tobacco Use among South Asian Immigrants in the Northeastern United States. J Oncol (2011) 0.88
Grm5 expression is not required for the oncogenic role of Grm1 in melanocytes. Neuropharmacology (2005) 0.87
Essential roles of BCCIP in mouse embryonic development and structural stability of chromosomes. PLoS Genet (2011) 0.86
Enrichment of human prostate cancer cells with tumor initiating properties in mouse and zebrafish xenografts by differential adhesion. Prostate (2013) 0.86
New prenylated benzoic acid and other constituents from almond hulls (Prunus amygdalus Batsch). J Agric Food Chem (2002) 0.86
Autophagy for the avoidance of degenerative, inflammatory, infectious, and neoplastic disease. Curr Opin Cell Biol (2010) 0.86
Inhibiting progression of coronary calcification using Aged Garlic Extract in patients receiving statin therapy: a preliminary study. Prev Med (2004) 0.85
Ammonificins A and B, hydroxyethylamine chroman derivatives from a cultured marine hydrothermal vent bacterium, Thermovibrio ammonificans. J Nat Prod (2009) 0.84
Analysis of theaflavins and thearubigins from black tea extract by MALDI-TOF mass spectrometry. J Agric Food Chem (2004) 0.83