Published in Biol Psychiatry on April 15, 2005
PPARalpha and PPARgamma attenuate HIV-induced dysregulation of tight junction proteins by modulations of matrix metalloproteinase and proteasome activities. FASEB J (2009) 1.29
Long-term pioglitazone treatment improves learning and attenuates pathological markers in a mouse model of Alzheimer's disease. J Alzheimers Dis (2012) 1.03
Pro-/anti-inflammatory dysregulation in patients with first episode of psychosis: toward an integrative inflammatory hypothesis of schizophrenia. Schizophr Bull (2013) 0.98
PPARalpha and PPARgamma effectively protect against HIV-induced inflammatory responses in brain endothelial cells. J Neurochem (2008) 0.95
Effects of long-term pioglitazone treatment on peripheral and central markers of aging. PLoS One (2010) 0.90
Neuroinflammation resulting from covert brain invasion by common viruses - a potential role in local and global neurodegeneration. Med Hypotheses (2010) 0.83
Peroxisome proliferator activating receptor (PPAR) in cerebral malaria (CM): a novel target for an additional therapy. Eur J Clin Microbiol Infect Dis (2010) 0.81
Physiological responses to acute psychological stress are reduced by the PPARγ agonist rosiglitazone. Endocrinology (2012) 0.80
Analgesic tolerance to morphine is regulated by PPARγ. Br J Pharmacol (2014) 0.79
Protein targets of acrylamide adduct formation in cultured rat dopaminergic cells. Toxicol Lett (2013) 0.79
Potential role of pioglitazone, caffeic acid and their combination against fatigue syndrome-induced behavioural, biochemical and mitochondrial alterations in mice. Inflammopharmacology (2010) 0.78
Genetic deletion of neuronal PPARγ enhances the emotional response to acute stress and exacerbates anxiety: An effect reversed by rescue of amygdala PPARγ function. J Neurosci (2016) 0.77
PPARγ and stress: implications for aging. Exp Gerontol (2012) 0.77
Chronic Noise Exposure Acts Cumulatively to Exacerbate Alzheimer's Disease-Like Amyloid-β Pathology and Neuroinflammation in the Rat Hippocampus. Sci Rep (2015) 0.76
Pro-/antiinflammatory dysregulation in early psychosis: results from a 1-year follow-up study. Int J Neuropsychopharmacol (2014) 0.76
LPS induces mediators of neuroinflammation, cell proliferation, and GFAP expression in human astrocytoma cells U373MG: the anti-inflammatory and anti-proliferative effect of guggulipid. Neurol Sci (2013) 0.76
Role of anti-diabetic drugs as therapeutic agents in Alzheimer's disease. EXCLI J (2015) 0.75
PPARγ as a therapeutic target to rescue mitochondrial function in neurological disease. Free Radic Biol Med (2016) 0.75
The Atypical Antipsychotic Paliperidone Regulates Endogenous Antioxidant/Anti-Inflammatory Pathways in Rat Models of Acute and Chronic Restraint Stress. Neurotherapeutics (2016) 0.75
Assessing competence of broccoli consumption on inflammatory and antioxidant pathways in restraint-induced models: estimation in rat hippocampus and prefrontal cortex. Biomed Res Int (2013) 0.75
PPARγ mRNA in the adult mouse hypothalamus: distribution and regulation in response to dietary challenges. Front Neuroanat (2015) 0.75
Plasma metalloproteinase-9 concentration predicts hemorrhagic transformation in acute ischemic stroke. Stroke (2003) 3.18
Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke. Circulation (2007) 2.94
The increase of circulating endothelial progenitor cells after acute ischemic stroke is associated with good outcome. Stroke (2007) 1.73
The prediction of malignant cerebral infarction by molecular brain barrier disruption markers. Stroke (2005) 1.58
Toll-like receptor 4 is involved in subacute stress-induced neuroinflammation and in the worsening of experimental stroke. Stroke (2008) 1.48
Toll-like receptor 4 is involved in neuroprotection afforded by ischemic preconditioning. J Neurochem (2009) 1.34
Stress as a neuroinflammatory condition in brain: damaging and protective mechanisms. Neurosci Biobehav Rev (2008) 1.34
CCL2/MCP-1 modulation of microglial activation and proliferation. J Neuroinflammation (2011) 1.27
Cannabinoid type 2 receptor activation downregulates stroke-induced classic and alternative brain macrophage/microglial activation concomitant to neuroprotection. Stroke (2011) 1.24
N2 neutrophils, novel players in brain inflammation after stroke: modulation by the PPARγ agonist rosiglitazone. Stroke (2013) 1.24
Mitochondrial respiratory chain and free radical generation in stroke. Free Radic Biol Med (2005) 1.23
Astrocyte-derived MCP-1 mediates neuroprotective effects of noradrenaline. J Neurosci (2009) 1.22
Validation of housekeeping genes for quantitative real-time PCR in in-vivo and in-vitro models of cerebral ischaemia. BMC Mol Biol (2009) 1.22
Amelioration of ischemic brain damage by peritoneal dialysis. J Clin Invest (2013) 1.21
Synthesis of lipoxin A4 by 5-lipoxygenase mediates PPARgamma-dependent, neuroprotective effects of rosiglitazone in experimental stroke. J Neurosci (2009) 1.21
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 cause potent neuroprotection after experimental stroke through noncompletely overlapping mechanisms. J Cereb Blood Flow Metab (2006) 1.17
The increase in TNF-alpha levels is implicated in NF-kappaB activation and inducible nitric oxide synthase expression in brain cortex after immobilization stress. Neuropsychopharmacology (2002) 1.14
Ischemic preconditioning reveals that GLT1/EAAT2 glutamate transporter is a novel PPARgamma target gene involved in neuroprotection. J Cereb Blood Flow Metab (2007) 1.13
A polymorphism in the EAAT2 promoter is associated with higher glutamate concentrations and higher frequency of progressing stroke. J Exp Med (2006) 1.12
Activation of liver X receptors promotes neuroprotection and reduces brain inflammation in experimental stroke. Circulation (2008) 1.10
The release of tumor necrosis factor-alpha is associated with ischemic tolerance in human stroke. Ann Neurol (2003) 1.10
Silent information regulator 1 protects the brain against cerebral ischemic damage. Stroke (2013) 1.09
TNFR1 upregulation mediates tolerance after brain ischemic preconditioning. J Cereb Blood Flow Metab (2005) 1.08
Implication of the Toll-like receptor 4 pathway in the response to interferon-β in multiple sclerosis. Ann Neurol (2011) 1.07
The metabolic syndrome and stroke: potential treatment approaches. Stroke (2007) 1.05
In vitro ischemic tolerance involves upregulation of glutamate transport partly mediated by the TACE/ADAM17-tumor necrosis factor-alpha pathway. J Neurosci (2004) 1.05
Mitochondria and reactive oxygen and nitrogen species in neurological disorders and stroke: Therapeutic implications. Adv Drug Deliv Rev (2009) 1.05
A mouse model of hemorrhagic transformation by delayed tissue plasminogen activator administration after in situ thromboembolic stroke. Stroke (2010) 1.04
Neuroprotection afforded by prior citicoline administration in experimental brain ischemia: effects on glutamate transport. Neurobiol Dis (2005) 1.03
The effects of physical and psychological stress on the gastro-intestinal tract: lessons from animal models. Curr Mol Med (2008) 1.03
Dual role of nitric oxide in adult neurogenesis. Brain Res Brain Res Rev (2005) 1.03
Chronic blockade of cannabinoid CB2 receptors induces anxiolytic-like actions associated with alterations in GABA(A) receptors. Br J Pharmacol (2012) 1.02
Induction of cyclooxygenase-2 accounts for restraint stress-induced oxidative status in rat brain. Neuropsychopharmacology (2003) 1.02
Effects of peroxisome proliferator-activated receptor gamma agonists on brain glucose and glutamate transporters after stress in rats. Neuropsychopharmacology (2006) 0.99
The role of PPARgamma on restoration of colonic homeostasis after experimental stress-induced inflammation and dysfunction. Gastroenterology (2007) 0.99
Pro-/anti-inflammatory dysregulation in patients with first episode of psychosis: toward an integrative inflammatory hypothesis of schizophrenia. Schizophr Bull (2013) 0.98
Characterization of the neuroprotective effect of the cannabinoid agonist WIN-55212 in an in vitro model of hypoxic-ischemic brain damage in newborn rats. Pediatr Res (2006) 0.97
Mangiferin decreases inflammation and oxidative damage in rat brain after stress. Eur J Nutr (2011) 0.97
Rosiglitazone-induced CD36 up-regulation resolves inflammation by PPARγ and 5-LO-dependent pathways. J Leukoc Biol (2013) 0.97
Ischemic preconditioning: a novel target for neuroprotective therapy. Cerebrovasc Dis (2006) 0.96
Involvement of IL-1beta in acute stress-induced worsening of cerebral ischaemia in rats. Eur Neuropsychopharmacol (2007) 0.95
The anti-inflammatory prostaglandin 15d-PGJ2 and its nuclear receptor PPARgamma are decreased in schizophrenia. Schizophr Res (2011) 0.95
Increased plasma levels of 15-deoxyDelta prostaglandin J2 are associated with good outcome in acute atherothrombotic ischemic stroke. Stroke (2005) 0.94
Stress-induced oxidative changes in brain. CNS Neurol Disord Drug Targets (2006) 0.94
The nonthiazolidinedione PPARgamma agonist L-796,449 is neuroprotective in experimental stroke. J Neuropathol Exp Neurol (2005) 0.94
Increased body iron stores are associated with poor outcome after thrombolytic treatment in acute stroke. Stroke (2006) 0.94
Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression. J Neuroinflammation (2011) 0.93
Risperidone normalizes increased inflammatory parameters and restores anti-inflammatory pathways in a model of neuroinflammation. Int J Neuropsychopharmacol (2011) 0.92
Regulatory role of cannabinoid receptor 1 in stress-induced excitotoxicity and neuroinflammation. Neuropsychopharmacology (2010) 0.92
Stress mediators regulate brain prostaglandin synthesis and peroxisome proliferator-activated receptor-gamma activation after stress in rats. Endocrinology (2007) 0.92
Colonic bacterial translocation as a possible factor in stress-worsening experimental stroke outcome. Am J Physiol Regul Integr Comp Physiol (2009) 0.92