The anti-inflammatory prostaglandin 15d-PGJ2 and its nuclear receptor PPARgamma are decreased in schizophrenia.

PubWeight™: 0.95‹?› | Rank: Top 15%

🔗 View Article (PMID 21334179)

Published in Schizophr Res on February 18, 2011

Authors

Isabel Martínez-Gras1, Beatriz G Pérez-Nievas, Borja García-Bueno, José L M Madrigal, Eva Andrés-Esteban, Roberto Rodríguez-Jiménez, Janet Hoenicka, Tomás Palomo, Gabriel Rubio, Juan C Leza

Author Affiliations

1: Department of Psychiatry, Faculty of Medicine, Complutense University, Madrid, Spain. isabelmgras@gmail.com

Articles citing this

Neuroinflammation and psychiatric illness. J Neuroinflammation (2013) 1.42

Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in the postmortem frontal cortex from schizophrenia patients. Schizophr Res (2013) 1.01

Pro-/anti-inflammatory dysregulation in patients with first episode of psychosis: toward an integrative inflammatory hypothesis of schizophrenia. Schizophr Bull (2013) 0.98

Inflammation and the two-hit hypothesis of schizophrenia. Neurosci Biobehav Rev (2013) 0.98

SNP-based analysis of neuroactive ligand-receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response: data from the CATIE study. Schizophr Res (2011) 0.93

Molecular profiles of parvalbumin-immunoreactive neurons in the superior temporal cortex in schizophrenia. J Neurogenet (2014) 0.92

Lipidomics profile of a NAPE-PLD KO mouse provides evidence of a broader role of this enzyme in lipid metabolism in the brain. Biochim Biophys Acta (2016) 0.82

Evidence of Mitochondrial Dysfunction within the Complex Genetic Etiology of Schizophrenia. Mol Neuropsychiatry (2015) 0.81

Evidence of activation of the Toll-like receptor-4 proinflammatory pathway in patients with schizophrenia. J Psychiatry Neurosci (2016) 0.78

Metabolic and inflammatory genes in schizophrenia. Psychiatry Res (2014) 0.78

Eicosanoids Derived From Arachidonic Acid and Their Family Prostaglandins and Cyclooxygenase in Psychiatric Disorders. Curr Neuropharmacol (2015) 0.78

Autophagy Modulation in Disease Therapy: Where Do We Stand? Curr Pathobiol Rep (2013) 0.78

Pro-/antiinflammatory dysregulation in early psychosis: results from a 1-year follow-up study. Int J Neuropsychopharmacol (2014) 0.76

BDNF and NGF Signalling in Early Phases of Psychosis: Relationship With Inflammation and Response to Antipsychotics After 1 Year. Schizophr Bull (2015) 0.75

Articles by these authors

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia. Ann Neurol (2004) 9.62

Dual roles for perivascular macrophages in immune-to-brain signaling. Neuron (2010) 2.24

The role of behavioral impulsivity in the development of alcohol dependence: a 4-year follow-up study. Alcohol Clin Exp Res (2008) 1.60

Toll-like receptor 4 is involved in subacute stress-induced neuroinflammation and in the worsening of experimental stroke. Stroke (2008) 1.48

Stress as a neuroinflammatory condition in brain: damaging and protective mechanisms. Neurosci Biobehav Rev (2008) 1.34

History of the discovery and clinical introduction of chlorpromazine. Ann Clin Psychiatry (2006) 1.31

CCL2/MCP-1 modulation of microglial activation and proliferation. J Neuroinflammation (2011) 1.27

Impaired action of anxiolytic drugs in mice deficient in cannabinoid CB1 receptors. Neuropharmacology (2004) 1.25

Astrocyte-derived MCP-1 mediates neuroprotective effects of noradrenaline. J Neurosci (2009) 1.22

Hypofunction of right temporoparietal cortex during emotional arousal in depression. Arch Gen Psychiatry (2008) 1.18

The increase in TNF-alpha levels is implicated in NF-kappaB activation and inducible nitric oxide synthase expression in brain cortex after immobilization stress. Neuropsychopharmacology (2002) 1.14

Increase in gray matter and decrease in white matter volumes in the cortex during treatment with atypical neuroleptics in schizophrenia. Schizophr Res (2005) 1.09

TNFR1 upregulation mediates tolerance after brain ischemic preconditioning. J Cereb Blood Flow Metab (2005) 1.08

In vitro ischemic tolerance involves upregulation of glutamate transport partly mediated by the TACE/ADAM17-tumor necrosis factor-alpha pathway. J Neurosci (2004) 1.05

A new mutation of the tau gene, G303V, in early-onset familial progressive supranuclear palsy. Arch Neurol (2005) 1.04

The effects of physical and psychological stress on the gastro-intestinal tract: lessons from animal models. Curr Mol Med (2008) 1.03

Neuroprotection afforded by prior citicoline administration in experimental brain ischemia: effects on glutamate transport. Neurobiol Dis (2005) 1.03

Dual role of nitric oxide in adult neurogenesis. Brain Res Brain Res Rev (2005) 1.03

Chronic blockade of cannabinoid CB2 receptors induces anxiolytic-like actions associated with alterations in GABA(A) receptors. Br J Pharmacol (2012) 1.02

Induction of cyclooxygenase-2 accounts for restraint stress-induced oxidative status in rat brain. Neuropsychopharmacology (2003) 1.02

Varieties of impulsivity in males with alcohol dependence: the role of Cluster-B personality disorder. Alcohol Clin Exp Res (2007) 1.02

Effects of peroxisome proliferator-activated receptor gamma agonists on brain glucose and glutamate transporters after stress in rats. Neuropsychopharmacology (2006) 0.99

The role of PPARgamma on restoration of colonic homeostasis after experimental stress-induced inflammation and dysfunction. Gastroenterology (2007) 0.99

Pro-/anti-inflammatory dysregulation in patients with first episode of psychosis: toward an integrative inflammatory hypothesis of schizophrenia. Schizophr Bull (2013) 0.98

Mangiferin decreases inflammation and oxidative damage in rat brain after stress. Eur J Nutr (2011) 0.97

Peroxisome proliferator-activated receptor gamma activation decreases neuroinflammation in brain after stress in rats. Biol Psychiatry (2005) 0.95

Negative signs and symptoms secondary to antipsychotics: a double-blind, randomized trial of a single dose of placebo, haloperidol, and risperidone in healthy volunteers. Am J Psychiatry (2006) 0.95

Involvement of IL-1beta in acute stress-induced worsening of cerebral ischaemia in rats. Eur Neuropsychopharmacol (2007) 0.95

Stress-induced oxidative changes in brain. CNS Neurol Disord Drug Targets (2006) 0.94

The nonthiazolidinedione PPARgamma agonist L-796,449 is neuroprotective in experimental stroke. J Neuropathol Exp Neurol (2005) 0.94

Psychiatry and political-institutional abuse from the historical perspective: the ethical lessons of the Nuremberg Trial on their 60th anniversary. Prog Neuropsychopharmacol Biol Psychiatry (2006) 0.94

Gender-specific COMT Val158Met polymorphism association in Spanish schizophrenic patients. Am J Med Genet B Neuropsychiatr Genet (2010) 0.93

Chronic ethanol consumption regulates cannabinoid CB1 receptor gene expression in selected regions of rat brain. Alcohol Alcohol (2004) 0.93

Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression. J Neuroinflammation (2011) 0.93

Anatomical and functional cerebral variables associated with basal symptoms but not risperidone response in minimally treated schizophrenia. Psychiatry Res (2003) 0.92

Risperidone normalizes increased inflammatory parameters and restores anti-inflammatory pathways in a model of neuroinflammation. Int J Neuropsychopharmacol (2011) 0.92

Role of endocannabinoid system in mental diseases. Neurotox Res (2004) 0.92

Regulatory role of cannabinoid receptor 1 in stress-induced excitotoxicity and neuroinflammation. Neuropsychopharmacology (2010) 0.92

Stress mediators regulate brain prostaglandin synthesis and peroxisome proliferator-activated receptor-gamma activation after stress in rats. Endocrinology (2007) 0.92

The ANKK1 gene associated with addictions is expressed in astroglial cells and upregulated by apomorphine. Biol Psychiatry (2010) 0.92

Colonic bacterial translocation as a possible factor in stress-worsening experimental stroke outcome. Am J Physiol Regul Integr Comp Physiol (2009) 0.92

Randomized trial of clozapine vs. risperidone in treatment-naïve first-episode schizophrenia: results after one year. Schizophr Res (2013) 0.92

Expression of nitrotyrosine and oxidative consequences in the trabecular meshwork of patients with primary open-angle glaucoma. Invest Ophthalmol Vis Sci (2008) 0.92

The ANKK1 kinase gene and psychiatric disorders. Neurotox Res (2009) 0.91

Genetic linkage of autosomal dominant progressive supranuclear palsy to 1q31.1. Ann Neurol (2005) 0.91

Relationship between cyclooxygenase-2 and nitric oxide synthase-2 in rat cortex after stress. Eur J Neurosci (2003) 0.90

Cerebral metabolic changes induced by clozapine in schizophrenia and related to clinical improvement. Psychopharmacology (Berl) (2004) 0.89

Experience with injectable long-acting risperidone in long-term therapy after an acute episode of schizophrenia: the SPHERE Study. Expert Rev Neurother (2009) 0.89

Lower prefrontal gray matter volume in schizophrenia in chronic but not in first episode schizophrenia patients. Psychiatry Res (2004) 0.88

Prefrontal atrophy in first episodes of schizophrenia associated with limbic metabolic hyperactivity. J Psychiatr Res (2005) 0.88

Upregulation of TACE/ADAM17 after ischemic preconditioning is involved in brain tolerance. J Cereb Blood Flow Metab (2002) 0.87

Anti-inflammatory effects of Mangifera indica L. extract in a model of colitis. World J Gastroenterol (2010) 0.87

The anti-inflammatory prostaglandin 15d-PGJ2 decreases oxidative/nitrosative mediators in brain after acute stress in rats. Psychopharmacology (Berl) (2005) 0.87

Steele-Richardson-Olszewski syndrome in a patient with a single C212Y mutation in the parkin protein. Mov Disord (2002) 0.87

Bipolar disorder as an emerging pathology in the scientific literature: a bibliometric approach. J Affect Disord (2006) 0.87

Naltrexone improves outcome of a controlled drinking program. J Subst Abuse Treat (2002) 0.86

Bibliometric analysis of biomedical publications on SSRI during 1980-2000. Depress Anxiety (2003) 0.86

TNF-alpha converting enzyme (TACE) protein expression in different clinical subtypes of multiple sclerosis. J Neurol (2006) 0.86

Inhibition of iNOS activity by 1400W decreases glutamate release and ameliorates stroke outcome after experimental ischemia. Neurobiol Dis (2005) 0.86

Is there a role for the nuclear receptor PPARγ in neuropsychiatric diseases? Int J Neuropsychopharmacol (2010) 0.86

[Psychometric performance of the 6th version of the Addiction Severity Index in Spanish (ASI-6)]. Psicothema (2010) 0.85

Chronic immobilisation stress ameliorates clinical score and neuroinflammation in a MOG-induced EAE in Dark Agouti rats: mechanisms implicated. J Neuroinflammation (2010) 0.85

Dorsolateral prefrontal and superior temporal volume deficits in first-episode psychoses that evolve into schizophrenia. Eur Arch Psychiatry Clin Neurosci (2005) 0.85

Differential dorsolateral prefrontal cortex activation during a verbal n-back task according to sensory modality. Behav Brain Res (2009) 0.85

Cannabinoid/agonist WIN 55,212-2 reduces cardiac ischaemia–reperfusion injury in Zucker diabetic fatty rats: role of CB2 receptors and iNOS/eNOS. Diabetes Metab Res Rev (2011) 0.84

Dosing and switching of paliperidone ER in patients with schizophrenia: recommendations for clinical practice. Ann Gen Psychiatry (2014) 0.84

Anatomical and functional brain variables associated with clozapine response in treatment-resistant schizophrenia. Psychiatry Res (2003) 0.84

Differences in basal cannabinoid CB1 receptor function in selective brain areas and vulnerability to voluntary alcohol consumption in Fawn Hooded and Wistar rats. Alcohol Alcohol (2004) 0.84