Published in J Endotoxin Res on January 01, 2005
Capsule-mediated immune evasion: a new hypothesis explaining aspects of typhoid fever pathogenesis. Infect Immun (2006) 1.50
Modulating the innate immune response by combinatorial engineering of endotoxin. Proc Natl Acad Sci U S A (2013) 1.45
An outer membrane enzyme encoded by Salmonella typhimurium lpxR that removes the 3'-acyloxyacyl moiety of lipid A. J Biol Chem (2006) 1.39
Recognition of lipid A variants by the TLR4-MD-2 receptor complex. Front Cell Infect Microbiol (2013) 1.14
Antimicrobial peptides activate the Rcs regulon through the outer membrane lipoprotein RcsF. J Bacteriol (2010) 0.99
Treponema denticola does not induce production of common innate immune mediators from primary gingival epithelial cells. Oral Microbiol Immunol (2008) 0.88
The PmrAB system-inducing conditions control both lipid A remodeling and O-antigen length distribution, influencing the Salmonella Typhimurium-host interactions. J Biol Chem (2012) 0.80
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat Immunol (2006) 9.64
Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients. Proc Natl Acad Sci U S A (2006) 8.85
Salmonellae interplay with host cells. Nat Rev Microbiol (2008) 5.26
LPS, TLR4 and infectious disease diversity. Nat Rev Microbiol (2005) 5.25
Aminoglycoside antibiotics induce bacterial biofilm formation. Nature (2005) 4.93
Recognition of antimicrobial peptides by a bacterial sensor kinase. Cell (2005) 4.78
Human Toll-like receptor 4 recognizes host-specific LPS modifications. Nat Immunol (2002) 3.56
Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock. Science (2013) 3.56
Pseudomonas aeruginosa activates caspase 1 through Ipaf. Proc Natl Acad Sci U S A (2008) 2.99
Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients. Mol Microbiol (2007) 2.87
PmrAB, a two-component regulatory system of Pseudomonas aeruginosa that modulates resistance to cationic antimicrobial peptides and addition of aminoarabinose to lipid A. J Bacteriol (2004) 2.80
Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains. Genome Biol (2007) 2.68
Factors affecting the escape of Francisella tularensis from the phagolysosome. J Med Microbiol (2004) 2.57
Cyclic di-GMP as a bacterial second messenger. Microbiology (2004) 2.54
Variation in lipid A structure in the pathogenic yersiniae. Mol Microbiol (2004) 2.28
Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation. Cell Host Microbe (2008) 2.21
Structural characterization of the molecular platform for type III secretion system assembly. Nature (2005) 2.20
Respiratory epithelial cells regulate lung inflammation in response to inhaled endotoxin. Am J Physiol Lung Cell Mol Physiol (2004) 2.19
Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors. Infect Immun (2006) 2.18
Analysis of the genome of the Escherichia coli O157:H7 2006 spinach-associated outbreak isolate indicates candidate genes that may enhance virulence. Infect Immun (2009) 2.07
LPS remodeling is an evolved survival strategy for bacteria. Proc Natl Acad Sci U S A (2012) 2.05
Are pathogenic bacteria just looking for food? Metabolism and microbial pathogenesis. Trends Microbiol (2011) 2.03
A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system. Nat Struct Mol Biol (2009) 2.02
Regulation of Salmonella typhimurium virulence gene expression by cationic antimicrobial peptides. Mol Microbiol (2003) 2.01
Asymmetrical distribution of the second messenger c-di-GMP upon bacterial cell division. Science (2010) 1.99
Activation of the bacterial sensor kinase PhoQ by acidic pH. Mol Cell (2007) 1.98
Precursor acquisition independent from ion count: how to dive deeper into the proteomics ocean. Anal Chem (2009) 1.96
Selection for Staphylococcus aureus small-colony variants due to growth in the presence of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2006) 1.95
Type IV pili-mediated secretion modulates Francisella virulence. Mol Microbiol (2006) 1.83
The TLR4 antagonist Eritoran protects mice from lethal influenza infection. Nature (2013) 1.78
Fecal microbial transplant effect on clinical outcomes and fecal microbiome in active Crohn's disease. Inflamm Bowel Dis (2015) 1.74
Pseudomonas aeruginosa lasR mutants are associated with cystic fibrosis lung disease progression. J Cyst Fibros (2008) 1.71
PhoPQ-mediated regulation produces a more robust permeability barrier in the outer membrane of Salmonella enterica serovar typhimurium. J Bacteriol (2007) 1.70
Genome mosaicism is conserved but not unique in Pseudomonas aeruginosa isolates from the airways of young children with cystic fibrosis. Environ Microbiol (2003) 1.68
3-O-deacylation of lipid A by PagL, a PhoP/PhoQ-regulated deacylase of Salmonella typhimurium, modulates signaling through Toll-like receptor 4. J Biol Chem (2004) 1.67
Identification of an orphan response regulator required for the virulence of Francisella spp. and transcription of pathogenicity island genes. Infect Immun (2007) 1.66
Pseudomonas aeruginosa in vitro phenotypes distinguish cystic fibrosis infection stages and outcomes. Am J Respir Crit Care Med (2014) 1.66
Human Toll-like receptor 4 responses to P. gingivalis are regulated by lipid A 1- and 4'-phosphatase activities. Cell Microbiol (2009) 1.66
The structure and function of Francisella lipopolysaccharide. Ann N Y Acad Sci (2007) 1.64
Metal bridges between the PhoQ sensor domain and the membrane regulate transmembrane signaling. J Mol Biol (2005) 1.61
A Francisella mutant in lipid A carbohydrate modification elicits protective immunity. PLoS Pathog (2008) 1.58
Characterization of protein cross-links via mass spectrometry and an open-modification search strategy. Anal Chem (2008) 1.56
Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton. Mol Microbiol (2003) 1.55
Potential source of Francisella tularensis live vaccine strain attenuation determined by genome comparison. Infect Immun (2006) 1.55
Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS. Proc Natl Acad Sci U S A (2014) 1.54
Role of the Salmonella pathogenicity island 1 (SPI-1) protein InvB in type III secretion of SopE and SopE2, two Salmonella effector proteins encoded outside of SPI-1. J Bacteriol (2003) 1.54
Burkholderia thailandensis as a model system for the study of the virulence-associated type III secretion system of Burkholderia pseudomallei. Infect Immun (2008) 1.52
Nutrient availability as a mechanism for selection of antibiotic tolerant Pseudomonas aeruginosa within the CF airway. PLoS Pathog (2010) 1.50
The Salmonella enterica serovar typhimurium translocated effectors SseJ and SifB are targeted to the Salmonella-containing vacuole. Infect Immun (2003) 1.49
The Salmonellae PhoQ sensor: mechanisms of detection of phagosome signals. Cell Microbiol (2008) 1.49
Differentiation and distribution of colistin- and sodium dodecyl sulfate-tolerant cells in Pseudomonas aeruginosa biofilms. J Bacteriol (2006) 1.46
Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS. Nature (2008) 1.45
Genome-specific gas-phase fractionation strategy for improved shotgun proteomic profiling of proteotypic peptides. Anal Chem (2008) 1.44
The bacterial second messenger c-di-GMP: mechanisms of signalling. Cell Microbiol (2011) 1.44
Evolution of Burkholderia pseudomallei in recurrent melioidosis. PLoS One (2012) 1.43
The Pseudomonas aeruginosa lipid A deacylase: selection for expression and loss within the cystic fibrosis airway. J Bacteriol (2006) 1.43
Assembly of the type III secretion needle complex of Salmonella typhimurium. Microbes Infect (2002) 1.41
The microbiome and inflammatory bowel disease: is there a therapeutic role for fecal microbiota transplantation? Am J Gastroenterol (2012) 1.40
Quantitative proteomic analysis indicates increased synthesis of a quinolone by Pseudomonas aeruginosa isolates from cystic fibrosis airways. Proc Natl Acad Sci U S A (2003) 1.39
An inhibitor of gram-negative bacterial virulence protein secretion. Cell Host Microbe (2008) 1.39
Structural heterogeneity and environmentally regulated remodeling of Francisella tularensis subspecies novicida lipid A characterized by tandem mass spectrometry. J Am Soc Mass Spectrom (2007) 1.37
Characterization of late acyltransferase genes of Yersinia pestis and their role in temperature-dependent lipid A variation. J Bacteriol (2006) 1.34
PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients. Antimicrob Agents Chemother (2011) 1.33
Activation of Toll-like receptors by Burkholderia pseudomallei. BMC Immunol (2008) 1.33
Rapid 16S rRNA next-generation sequencing of polymicrobial clinical samples for diagnosis of complex bacterial infections. PLoS One (2013) 1.33
PmrB mutations promote polymyxin resistance of Pseudomonas aeruginosa isolated from colistin-treated cystic fibrosis patients. Antimicrob Agents Chemother (2011) 1.32
SseJ deacylase activity by Salmonella enterica serovar Typhimurium promotes virulence in mice. Infect Immun (2005) 1.30
Salmonella enterica serovar enteritidis core O polysaccharide conjugated to H:g,m flagellin as a candidate vaccine for protection against invasive infection with S. enteritidis. Infect Immun (2011) 1.29
A Salmonella type III secretion effector interacts with the mammalian serine/threonine protein kinase PKN1. Cell Microbiol (2006) 1.27
Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death. Proc Natl Acad Sci U S A (2012) 1.26
SpiC is required for translocation of Salmonella pathogenicity island 2 effectors and secretion of translocon proteins SseB and SseC. J Bacteriol (2002) 1.26
A Salmonella enterica serovar typhimurium translocated leucine-rich repeat effector protein inhibits NF-kappa B-dependent gene expression. Infect Immun (2003) 1.25
Exopolysaccharides from Burkholderia cenocepacia inhibit neutrophil chemotaxis and scavenge reactive oxygen species. J Biol Chem (2005) 1.23
Identification of an unconventional E3 binding surface on the UbcH5 ~ Ub conjugate recognized by a pathogenic bacterial E3 ligase. Proc Natl Acad Sci U S A (2010) 1.20
The response threshold of Salmonella PilZ domain proteins is determined by their binding affinities for c-di-GMP. Mol Microbiol (2012) 1.19
Unique lipid a modifications in Pseudomonas aeruginosa isolated from the airways of patients with cystic fibrosis. J Infect Dis (2007) 1.19
A genome-wide in vitro bacterial-infection screen reveals human variation in the host response associated with inflammatory disease. Am J Hum Genet (2009) 1.18
Determination of pyrophosphorylated forms of lipid A in Gram-negative bacteria using a multivaried mass spectrometric approach. Proc Natl Acad Sci U S A (2008) 1.18
Activities of vancomycin-containing regimens against colistin-resistant Acinetobacter baumannii clinical strains. Antimicrob Agents Chemother (2013) 1.17
mig-14 is a Salmonella gene that plays a role in bacterial resistance to antimicrobial peptides. J Bacteriol (2002) 1.16
Large-insert genome analysis technology detects structural variation in Pseudomonas aeruginosa clinical strains from cystic fibrosis patients. Genomics (2008) 1.14
PhoPQ regulates acidic glycerophospholipid content of the Salmonella Typhimurium outer membrane. Proc Natl Acad Sci U S A (2014) 1.14
Unique structural modifications are present in the lipopolysaccharide from colistin-resistant strains of Acinetobacter baumannii. Antimicrob Agents Chemother (2013) 1.14
Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica. PLoS Pathog (2012) 1.13
Substituted 2-imino-5-arylidenethiazolidin-4-one inhibitors of bacterial type III secretion. J Med Chem (2008) 1.13
Transcription of the SsrAB regulon is repressed by alkaline pH and is independent of PhoPQ and magnesium concentration. J Bacteriol (2002) 1.12
Pseudomonas aeruginosa lipid A diversity and its recognition by Toll-like receptor 4. J Endotoxin Res (2003) 1.11
Immunostimulatory properties of the emerging pathogen Stenotrophomonas maltophilia. Infect Immun (2007) 1.11