Published in Cell on August 12, 2005
Lipid A modification systems in gram-negative bacteria. Annu Rev Biochem (2007) 8.60
Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota. PLoS Biol (2007) 7.58
Antibiotics for emerging pathogens. Science (2009) 7.39
Stimulus perception in bacterial signal-transducing histidine kinases. Microbiol Mol Biol Rev (2006) 4.12
AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense. Trends Immunol (2009) 3.40
Inter-kingdom signalling: communication between bacteria and their hosts. Nat Rev Microbiol (2008) 3.15
TLR signaling is required for Salmonella typhimurium virulence. Cell (2011) 2.88
Outer membrane permeability and antibiotic resistance. Biochim Biophys Acta (2008) 2.73
The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2. Proc Natl Acad Sci U S A (2006) 2.63
A Staphylococcus aureus regulatory system that responds to host heme and modulates virulence. Cell Host Microbe (2007) 2.55
Gram-positive three-component antimicrobial peptide-sensing system. Proc Natl Acad Sci U S A (2007) 2.34
The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal Salmonella diarrhea. PLoS Pathog (2010) 2.17
Interaction of the GraRS two-component system with the VraFG ABC transporter to support vancomycin-intermediate resistance in Staphylococcus aureus. Antimicrob Agents Chemother (2007) 2.14
A PhoQ/P-regulated small RNA regulates sensitivity of Escherichia coli to antimicrobial peptides. Mol Microbiol (2009) 2.03
Life in the inflamed intestine, Salmonella style. Trends Microbiol (2009) 1.97
Protection of Sinorhizobium against host cysteine-rich antimicrobial peptides is critical for symbiosis. PLoS Biol (2011) 1.92
In vivo emergence of colistin resistance in Klebsiella pneumoniae producing KPC-type carbapenemases mediated by insertional inactivation of the PhoQ/PhoP mgrB regulator. Antimicrob Agents Chemother (2013) 1.83
Sensor complexes regulating two-component signal transduction. Curr Opin Struct Biol (2007) 1.82
The pmrCAB operon mediates polymyxin resistance in Acinetobacter baumannii ATCC 17978 and clinical isolates through phosphoethanolamine modification of lipid A. Antimicrob Agents Chemother (2011) 1.78
Adaptive resistance to the "last hope" antibiotics polymyxin B and colistin in Pseudomonas aeruginosa is mediated by the novel two-component regulatory system ParR-ParS. Antimicrob Agents Chemother (2010) 1.74
The SaeR/S gene regulatory system is essential for innate immune evasion by Staphylococcus aureus. J Infect Dis (2009) 1.74
PhoPQ-mediated regulation produces a more robust permeability barrier in the outer membrane of Salmonella enterica serovar typhimurium. J Bacteriol (2007) 1.70
Characterization of phagosome trafficking and identification of PhoP-regulated genes important for survival of Yersinia pestis in macrophages. Infect Immun (2006) 1.66
An essential complementary role of NF-kappaB pathway to microbicidal oxidants in Drosophila gut immunity. EMBO J (2006) 1.63
Dynorphin activates quorum sensing quinolone signaling in Pseudomonas aeruginosa. PLoS Pathog (2007) 1.60
Coordinated regulation of virulence during systemic infection of Salmonella enterica serovar Typhimurium. PLoS Pathog (2009) 1.58
Characterization of the sporulation initiation pathway of Clostridium difficile and its role in toxin production. J Bacteriol (2009) 1.57
De novo design of antimicrobial polymers, foldamers, and small molecules: from discovery to practical applications. Acc Chem Res (2010) 1.52
Crossing the line: selection and evolution of virulence traits. PLoS Pathog (2006) 1.49
Evidence for a novel protease governing regulated intramembrane proteolysis and resistance to antimicrobial peptides in Bacillus subtilis. Genes Dev (2006) 1.47
Induction of group A Streptococcus virulence by a human antimicrobial peptide. Proc Natl Acad Sci U S A (2008) 1.45
Feedback inhibition in the PhoQ/PhoP signaling system by a membrane peptide. PLoS Genet (2009) 1.40
Sensor histidine kinase is a β-lactam receptor and induces resistance to β-lactam antibiotics. Proc Natl Acad Sci U S A (2016) 1.40
Transcriptome analysis of the responses of Staphylococcus aureus to antimicrobial peptides and characterization of the roles of vraDE and vraSR in antimicrobial resistance. BMC Genomics (2009) 1.39
Antimicrobial peptides. Pharmaceuticals (Basel) (2013) 1.37
Visualization of vacuolar acidification-induced transcription of genes of pathogens inside macrophages. Mol Biol Cell (2005) 1.37
Transit through the flea vector induces a pretransmission innate immunity resistance phenotype in Yersinia pestis. PLoS Pathog (2010) 1.36
QseC mediates Salmonella enterica serovar typhimurium virulence in vitro and in vivo. Infect Immun (2009) 1.33
A putative gene cluster for aminoarabinose biosynthesis is essential for Burkholderia cenocepacia viability. J Bacteriol (2007) 1.31
Recognition of intestinal epithelial HIF-1alpha activation by Pseudomonas aeruginosa. Am J Physiol Gastrointest Liver Physiol (2006) 1.30
A bacterial mRNA leader that employs different mechanisms to sense disparate intracellular signals. Cell (2010) 1.27
The Staphylococcus aureus two-component regulatory system, GraRS, senses and confers resistance to selected cationic antimicrobial peptides. Infect Immun (2011) 1.25
High stimulus unmasks positive feedback in an autoregulated bacterial signaling circuit. Proc Natl Acad Sci U S A (2008) 1.24
Stimulus-dependent differential regulation in the Escherichia coli PhoQ PhoP system. Proc Natl Acad Sci U S A (2007) 1.22
Structural biology of membrane-intrinsic beta-barrel enzymes: sentinels of the bacterial outer membrane. Biochim Biophys Acta (2007) 1.22
A pmrA constitutive mutant sensitizes Escherichia coli to deoxycholic acid. J Bacteriol (2006) 1.21
Attenuation of the sensing capabilities of PhoQ in transition to obligate insect-bacterial association. PLoS Genet (2011) 1.20
Analysis of the networks controlling the antimicrobial-peptide-dependent induction of Klebsiella pneumoniae virulence factors. Infect Immun (2011) 1.19
Structure of the DNA-binding domain of the response regulator PhoP from Mycobacterium tuberculosis. Biochemistry (2007) 1.17
Salmonellae PhoPQ regulation of the outer membrane to resist innate immunity. Curr Opin Microbiol (2014) 1.16
Crystal structure and catalytic mechanism of the LPS 3-O-deacylase PagL from Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2006) 1.15
Salmonella synthesizing 1-dephosphorylated [corrected] lipopolysaccharide exhibits low endotoxic activity while retaining its immunogenicity. J Immunol (2011) 1.15
The N-terminal helix is a post-assembly clamp in the bacterial outer membrane protein PagP. J Mol Biol (2007) 1.13
Functional genomics of stress response in Pseudomonas putida KT2440. J Bacteriol (2006) 1.09
PagP crystallized from SDS/cosolvent reveals the route for phospholipid access to the hydrocarbon ruler. Structure (2010) 1.09
Regulation of type VI secretion system during Burkholderia pseudomallei infection. Infect Immun (2011) 1.07
Molecular mechanism for lateral lipid diffusion between the outer membrane external leaflet and a beta-barrel hydrocarbon ruler. Biochemistry (2009) 1.05
Membrane damage elicits an immunomodulatory program in Staphylococcus aureus. PLoS Pathog (2010) 1.05
Capsular antigen fraction 1 and Pla modulate the susceptibility of Yersinia pestis to pulmonary antimicrobial peptides such as cathelicidin. Infect Immun (2008) 1.04
The Xanthomonas oryzae pv. oryzae PhoPQ two-component system is required for AvrXA21 activity, hrpG expression, and virulence. J Bacteriol (2008) 1.04
Staphylococcus colonization of the skin and antimicrobial peptides. Expert Rev Dermatol (2010) 1.03
An inner membrane dioxygenase that generates the 2-hydroxymyristate moiety of Salmonella lipid A. Biochemistry (2008) 1.03
Bacterial sensing of antimicrobial peptides. Contrib Microbiol (2009) 1.03
Temperature and Mg2+ sensing by a novel PhoP-PhoQ two-component system for regulation of virulence in Edwardsiella tarda. J Biol Chem (2010) 1.01
Induction of the Yersinia pestis PhoP-PhoQ regulatory system in the flea and its role in producing a transmissible infection. J Bacteriol (2013) 1.01
Protecting against antimicrobial effectors in the phagosome allows SodCII to contribute to virulence in Salmonella enterica serovar Typhimurium. J Bacteriol (2010) 1.00
Increased expression of Mg(2+) transport proteins enhances the survival of Salmonella enterica at high temperature. Proc Natl Acad Sci U S A (2009) 1.00
Bright mutants of Vibrio fischeri ES114 reveal conditions and regulators that control bioluminescence and expression of the lux operon. J Bacteriol (2010) 1.00
The cia operon of Streptococcus mutans encodes a unique component required for calcium-mediated autoregulation. Mol Microbiol (2008) 1.00
Bacterial sensor kinase TodS interacts with agonistic and antagonistic signals. Proc Natl Acad Sci U S A (2007) 1.00
Antimicrobial peptides activate the Rcs regulon through the outer membrane lipoprotein RcsF. J Bacteriol (2010) 0.99
The broadly conserved regulator PhoP links pathogen virulence and membrane potential in Escherichia coli. Mol Microbiol (2011) 0.99
Activated by different signals, the PhoP/PhoQ two-component system differentially regulates metal uptake. J Bacteriol (2009) 0.99
Induction by cationic antimicrobial peptides and involvement in intrinsic polymyxin and antimicrobial peptide resistance, biofilm formation, and swarming motility of PsrA in Pseudomonas aeruginosa. J Bacteriol (2008) 0.98
The PhoQ histidine kinases of Salmonella and Pseudomonas spp. are structurally and functionally different: evidence that pH and antimicrobial peptide sensing contribute to mammalian pathogenesis. Mol Microbiol (2008) 0.97
The Erwinia chrysanthemi 3937 PhoQ sensor kinase regulates several virulence determinants. J Bacteriol (2006) 0.96
Molecular mechanism for establishment of signal-dependent regulation in the PhoP/PhoQ system. J Biol Chem (2008) 0.96
The CpxR/CpxA two-component system up-regulates two Tat-dependent peptidoglycan amidases to confer bacterial resistance to antimicrobial peptide. J Biol Chem (2010) 0.96
Impact of the Staphylococcus epidermidis LytSR two-component regulatory system on murein hydrolase activity, pyruvate utilization and global transcriptional profile. BMC Microbiol (2010) 0.96
Signal transduction in histidine kinases: insights from new structures. Structure (2015) 0.95
Promoter and riboswitch control of the Mg2+ transporter MgtA from Salmonella enterica. J Bacteriol (2009) 0.95
The promoter architectural landscape of the Salmonella PhoP regulon. Mol Microbiol (2012) 0.95
The hybrid sensor kinase RscS integrates positive and negative signals to modulate biofilm formation in Vibrio fischeri. J Bacteriol (2008) 0.95
The two-component system CprRS senses cationic peptides and triggers adaptive resistance in Pseudomonas aeruginosa independently of ParRS. Antimicrob Agents Chemother (2012) 0.95
PagP activation in the outer membrane triggers R3 core oligosaccharide truncation in the cytoplasm of Escherichia coli O157:H7. J Biol Chem (2007) 0.94
The two-component signal transduction system ArlRS regulates Staphylococcus epidermidis biofilm formation in an ica-dependent manner. PLoS One (2012) 0.93
The KdpD/KdpE two-component system: integrating K⁺ homeostasis and virulence. PLoS Pathog (2013) 0.93
Salmonella enterica serovar Typhimurium periplasmic superoxide dismutase SodCI is a member of the PhoPQ regulon and is induced in macrophages. J Bacteriol (2006) 0.93
A dual-signal regulatory circuit activates transcription of a set of divergent operons in Salmonella typhimurium. Proc Natl Acad Sci U S A (2008) 0.93
Gram-negative bacterial sensors for eukaryotic signal molecules. Sensors (Basel) (2009) 0.93
Role of RppA in the regulation of polymyxin b susceptibility, swarming, and virulence factor expression in Proteus mirabilis. Infect Immun (2008) 0.92
Structural properties of periplasmic SodCI that correlate with virulence in Salmonella enterica serovar Typhimurium. J Bacteriol (2007) 0.92
The roles of metal ions in regulation by riboswitches. Met Ions Life Sci (2011) 0.92
Determination of the physiological dimer interface of the PhoQ sensor domain. J Mol Biol (2008) 0.92
Genome expression analysis of nonproliferating intracellular Salmonella enterica serovar Typhimurium unravels an acid pH-dependent PhoP-PhoQ response essential for dormancy. Infect Immun (2012) 0.91
Bacterial Mg2+ homeostasis, transport, and virulence. Annu Rev Genet (2013) 0.91
Cationic antimicrobial peptide resistance mechanisms of streptococcal pathogens. Biochim Biophys Acta (2015) 0.91
Phosphorylation and ionic strength alter the LRAP-HAP interface in the N-terminus. Biochemistry (2013) 0.90
The effect of the potential PhoQ histidine kinase inhibitors on Shigella flexneri virulence. PLoS One (2011) 0.90
Mechanisms of Antimicrobial Peptide Resistance in Gram-Negative Bacteria. Antibiotics (Basel) (2015) 0.90
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat Immunol (2006) 9.64
Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients. Proc Natl Acad Sci U S A (2006) 8.85
Salmonellae interplay with host cells. Nat Rev Microbiol (2008) 5.26
Aminoglycoside antibiotics induce bacterial biofilm formation. Nature (2005) 4.93
Mutant adenosine deaminase 2 in a polyarteritis nodosa vasculopathy. N Engl J Med (2014) 4.70
E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages. Nat Struct Mol Biol (2007) 3.72
Human Toll-like receptor 4 recognizes host-specific LPS modifications. Nat Immunol (2002) 3.56
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids. Nature (2011) 3.40
A UbcH5/ubiquitin noncovalent complex is required for processive BRCA1-directed ubiquitination. Mol Cell (2006) 3.30
Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme. Nature (2006) 2.87
Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients. Mol Microbiol (2007) 2.87
PmrAB, a two-component regulatory system of Pseudomonas aeruginosa that modulates resistance to cationic antimicrobial peptides and addition of aminoarabinose to lipid A. J Bacteriol (2004) 2.80
Mutations in the DBP-deficiency protein HSD17B4 cause ovarian dysgenesis, hearing loss, and ataxia of Perrault Syndrome. Am J Hum Genet (2010) 2.76
Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains. Genome Biol (2007) 2.68
Cyclic di-GMP as a bacterial second messenger. Microbiology (2004) 2.54
Variation in lipid A structure in the pathogenic yersiniae. Mol Microbiol (2004) 2.28
Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation. Cell Host Microbe (2008) 2.21
Structural characterization of the molecular platform for type III secretion system assembly. Nature (2005) 2.20
Respiratory epithelial cells regulate lung inflammation in response to inhaled endotoxin. Am J Physiol Lung Cell Mol Physiol (2004) 2.19
Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors. Infect Immun (2006) 2.18
Mutations in mitochondrial histidyl tRNA synthetase HARS2 cause ovarian dysgenesis and sensorineural hearing loss of Perrault syndrome. Proc Natl Acad Sci U S A (2011) 2.11
Analysis of the genome of the Escherichia coli O157:H7 2006 spinach-associated outbreak isolate indicates candidate genes that may enhance virulence. Infect Immun (2009) 2.07
Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases. Mol Cell (2012) 2.07
Are pathogenic bacteria just looking for food? Metabolism and microbial pathogenesis. Trends Microbiol (2011) 2.03
A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system. Nat Struct Mol Biol (2009) 2.02
Regulation of Salmonella typhimurium virulence gene expression by cationic antimicrobial peptides. Mol Microbiol (2003) 2.01
Asymmetrical distribution of the second messenger c-di-GMP upon bacterial cell division. Science (2010) 1.99
Activation of the bacterial sensor kinase PhoQ by acidic pH. Mol Cell (2007) 1.98
Mass spectrometric and mutational analyses reveal Lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligase. J Biol Chem (2003) 1.97
Precursor acquisition independent from ion count: how to dive deeper into the proteomics ocean. Anal Chem (2009) 1.96
Selection for Staphylococcus aureus small-colony variants due to growth in the presence of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2006) 1.95
Type IV pili-mediated secretion modulates Francisella virulence. Mol Microbiol (2006) 1.83
Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex. Genes Dev (2003) 1.78
Fecal microbial transplant effect on clinical outcomes and fecal microbiome in active Crohn's disease. Inflamm Bowel Dis (2015) 1.74
Pseudomonas aeruginosa lasR mutants are associated with cystic fibrosis lung disease progression. J Cyst Fibros (2008) 1.71
PhoPQ-mediated regulation produces a more robust permeability barrier in the outer membrane of Salmonella enterica serovar typhimurium. J Bacteriol (2007) 1.70
Genome mosaicism is conserved but not unique in Pseudomonas aeruginosa isolates from the airways of young children with cystic fibrosis. Environ Microbiol (2003) 1.68
Crystal structures of the extracellular domain of LRP6 and its complex with DKK1. Nat Struct Mol Biol (2011) 1.68
3-O-deacylation of lipid A by PagL, a PhoP/PhoQ-regulated deacylase of Salmonella typhimurium, modulates signaling through Toll-like receptor 4. J Biol Chem (2004) 1.67
Pseudomonas aeruginosa in vitro phenotypes distinguish cystic fibrosis infection stages and outcomes. Am J Respir Crit Care Med (2014) 1.66
Structure and function of the PP2A-shugoshin interaction. Mol Cell (2009) 1.66
E2s: structurally economical and functionally replete. Biochem J (2011) 1.64
RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination. Biochim Biophys Acta (2013) 1.64
Metal bridges between the PhoQ sensor domain and the membrane regulate transmembrane signaling. J Mol Biol (2005) 1.61
Crystal structure of a beta-catenin/BCL9/Tcf4 complex. Mol Cell (2006) 1.61
OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function. Mol Cell (2012) 1.58
Characterization of protein cross-links via mass spectrometry and an open-modification search strategy. Anal Chem (2008) 1.56
Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton. Mol Microbiol (2003) 1.55
Crystal structure of a full-length beta-catenin. Structure (2008) 1.55
Potential source of Francisella tularensis live vaccine strain attenuation determined by genome comparison. Infect Immun (2006) 1.55
Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling. Sci Transl Med (2012) 1.54
Role of the Salmonella pathogenicity island 1 (SPI-1) protein InvB in type III secretion of SopE and SopE2, two Salmonella effector proteins encoded outside of SPI-1. J Bacteriol (2003) 1.54
Solid-state NMR and SAXS studies provide a structural basis for the activation of alphaB-crystallin oligomers. Nat Struct Mol Biol (2010) 1.53
Burkholderia thailandensis as a model system for the study of the virulence-associated type III secretion system of Burkholderia pseudomallei. Infect Immun (2008) 1.52
Mutations in LARS2, encoding mitochondrial leucyl-tRNA synthetase, lead to premature ovarian failure and hearing loss in Perrault syndrome. Am J Hum Genet (2013) 1.50
Nutrient availability as a mechanism for selection of antibiotic tolerant Pseudomonas aeruginosa within the CF airway. PLoS Pathog (2010) 1.50
The Salmonella enterica serovar typhimurium translocated effectors SseJ and SifB are targeted to the Salmonella-containing vacuole. Infect Immun (2003) 1.49
The Salmonellae PhoQ sensor: mechanisms of detection of phagosome signals. Cell Microbiol (2008) 1.49
Ubiquitin in motion: structural studies of the ubiquitin-conjugating enzyme∼ubiquitin conjugate. Biochemistry (2011) 1.46
Differentiation and distribution of colistin- and sodium dodecyl sulfate-tolerant cells in Pseudomonas aeruginosa biofilms. J Bacteriol (2006) 1.46
Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS. Nature (2008) 1.45
The bacterial second messenger c-di-GMP: mechanisms of signalling. Cell Microbiol (2011) 1.44
Genome-specific gas-phase fractionation strategy for improved shotgun proteomic profiling of proteotypic peptides. Anal Chem (2008) 1.44
Evolution of Burkholderia pseudomallei in recurrent melioidosis. PLoS One (2012) 1.43
The Pseudomonas aeruginosa lipid A deacylase: selection for expression and loss within the cystic fibrosis airway. J Bacteriol (2006) 1.43
Assembly of the type III secretion needle complex of Salmonella typhimurium. Microbes Infect (2002) 1.41
Estrogen receptor alpha is a putative substrate for the BRCA1 ubiquitin ligase. Proc Natl Acad Sci U S A (2007) 1.40
The microbiome and inflammatory bowel disease: is there a therapeutic role for fecal microbiota transplantation? Am J Gastroenterol (2012) 1.40
An inhibitor of gram-negative bacterial virulence protein secretion. Cell Host Microbe (2008) 1.39
Quantitative proteomic analysis indicates increased synthesis of a quinolone by Pseudomonas aeruginosa isolates from cystic fibrosis airways. Proc Natl Acad Sci U S A (2003) 1.39
N-terminal domain of alphaB-crystallin provides a conformational switch for multimerization and structural heterogeneity. Proc Natl Acad Sci U S A (2011) 1.36
Characterization of late acyltransferase genes of Yersinia pestis and their role in temperature-dependent lipid A variation. J Bacteriol (2006) 1.34
Recognition of the iso-ADP-ribose moiety in poly(ADP-ribose) by WWE domains suggests a general mechanism for poly(ADP-ribosyl)ation-dependent ubiquitination. Genes Dev (2012) 1.33
PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients. Antimicrob Agents Chemother (2011) 1.33
Rapid 16S rRNA next-generation sequencing of polymicrobial clinical samples for diagnosis of complex bacterial infections. PLoS One (2013) 1.33
Following Ariadne's thread: a new perspective on RBR ubiquitin ligases. BMC Biol (2012) 1.33
Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis. Proc Natl Acad Sci U S A (2013) 1.32
Structural basis of PP2A inhibition by small t antigen. PLoS Biol (2007) 1.32
PmrB mutations promote polymyxin resistance of Pseudomonas aeruginosa isolated from colistin-treated cystic fibrosis patients. Antimicrob Agents Chemother (2011) 1.32
The crystal structure of the beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT. Mol Cell (2002) 1.31
alphaB-crystallin: a hybrid solid-state/solution-state NMR investigation reveals structural aspects of the heterogeneous oligomer. J Mol Biol (2008) 1.31
SseJ deacylase activity by Salmonella enterica serovar Typhimurium promotes virulence in mice. Infect Immun (2005) 1.30
Crystal structure of a beta-catenin/APC complex reveals a critical role for APC phosphorylation in APC function. Mol Cell (2004) 1.29
A Salmonella type III secretion effector interacts with the mammalian serine/threonine protein kinase PKN1. Cell Microbiol (2006) 1.27
SpiC is required for translocation of Salmonella pathogenicity island 2 effectors and secretion of translocon proteins SseB and SseC. J Bacteriol (2002) 1.26
Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death. Proc Natl Acad Sci U S A (2012) 1.26
A Salmonella enterica serovar typhimurium translocated leucine-rich repeat effector protein inhibits NF-kappa B-dependent gene expression. Infect Immun (2003) 1.25
Identification of an unconventional E3 binding surface on the UbcH5 ~ Ub conjugate recognized by a pathogenic bacterial E3 ligase. Proc Natl Acad Sci U S A (2010) 1.20
The response threshold of Salmonella PilZ domain proteins is determined by their binding affinities for c-di-GMP. Mol Microbiol (2012) 1.19
Unique lipid a modifications in Pseudomonas aeruginosa isolated from the airways of patients with cystic fibrosis. J Infect Dis (2007) 1.19
A genome-wide in vitro bacterial-infection screen reveals human variation in the host response associated with inflammatory disease. Am J Hum Genet (2009) 1.18
mig-14 is a Salmonella gene that plays a role in bacterial resistance to antimicrobial peptides. J Bacteriol (2002) 1.16