Published in Clin Cancer Res on April 15, 2005
Identification of a bona fide microRNA biomarker in serum exosomes that predicts hepatocellular carcinoma recurrence after liver transplantation. Br J Cancer (2015) 1.07
Caveolin-1-mediated expression and secretion of kallikrein 6 in colon cancer cells. Neoplasia (2008) 1.01
Kallikrein 6 is a mediator of K-RAS-dependent migration of colon carcinoma cells. Biol Chem (2008) 0.96
CEACAM6 gene expression in intrahepatic cholangiocarcinoma. Br J Cancer (2006) 0.94
Correlation of hK6 expression with tumor recurrence and prognosis in advanced gastric cancer. Diagn Pathol (2013) 0.93
KLK6 and KLK13 predict tumor recurrence in epithelial ovarian carcinoma. Br J Cancer (2009) 0.90
Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signaling pathway in colon cancer cells. Am J Pathol (2011) 0.87
The use of kallikrein-related peptidases as adjuvant prognostic markers in colorectal cancer. Br J Cancer (2009) 0.87
Kallikrein-related peptidase 6 regulates epithelial-to-mesenchymal transition and serves as prognostic biomarker for head and neck squamous cell carcinoma patients. Mol Cancer (2015) 0.82
Lymph node tissue kallikrein-related peptidase 6 mRNA: a progression marker for colorectal cancer. Br J Cancer (2012) 0.81
Bone marrow and peripheral blood expression of ID1 in human gastric carcinoma patients is a bona fide indicator of lymph node and peritoneal metastasis. Br J Cancer (2009) 0.81
Differential Gene Expression Landscape of Co-Existing Cervical Pre-Cancer Lesions Using RNA-seq. Front Oncol (2014) 0.76
Correlation between KLK6 expression and the clinicopathological features of glioma. Contemp Oncol (Pozn) (2014) 0.75
Kallikrein-related peptidase 6 induces chemotherapeutic resistance by attenuating auranofin-induced cell death through activation of autophagy in gastric cancer. Oncotarget (2016) 0.75
Specific microRNA-mRNA Regulatory Network of Colon Cancer Invasion Mediated by Tissue Kallikrein-Related Peptidase 6. Neoplasia (2017) 0.75
Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers. Cancer Res (2011) 6.02
Clinical significance of circulating tumor cells, including cancer stem-like cells, in peripheral blood for recurrence and prognosis in patients with Dukes' stage B and C colorectal cancer. J Clin Oncol (2011) 4.48
Reprogramming of mouse and human cells to pluripotency using mature microRNAs. Cell Stem Cell (2011) 4.02
Characterization of a side population of cancer cells from human gastrointestinal system. Stem Cells (2005) 3.66
The wide spectrum of clinical manifestations in Sjögren's syndrome-associated neuropathy. Brain (2005) 3.65
CD13 is a therapeutic target in human liver cancer stem cells. J Clin Invest (2010) 3.60
CT-guided needle biopsy of lung lesions: a survey of severe complication based on 9783 biopsies in Japan. Eur J Radiol (2006) 3.39
Epithelial-mesenchymal transition in cancer development and its clinical significance. Cancer Sci (2009) 3.39
Familial cancer associated with a polymorphism in ARLTS1. N Engl J Med (2005) 3.35
17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration. Nat Med (2005) 3.19
Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma. Cancer Cell (2002) 3.12
Stat3 protects against Fas-induced liver injury by redox-dependent and -independent mechanisms. J Clin Invest (2003) 3.02
Survival benefit of bursectomy in patients with resectable gastric cancer: interim analysis results of a randomized controlled trial. Gastric Cancer (2011) 2.97
Aggresomes protect cells by enhancing the degradation of toxic polyglutamine-containing protein. Hum Mol Genet (2003) 2.89
CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer. Genome Res (2013) 2.57
Over- and under-expressed microRNAs in human colorectal cancer. Int J Oncol (2009) 2.34
Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial. Lancet Neurol (2010) 2.33
A large-scale study of MT1-MMP as a marker for isolated tumor cells in peripheral blood and bone marrow in gastric cancer cases. Ann Surg Oncol (2008) 2.32
The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43. Nat Commun (2013) 2.31
PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity. J Clin Invest (2003) 2.23
Circulating microRNA-21 as a novel biomarker for hepatocellular carcinoma. J Hepatol (2011) 2.18
Subcuticular sutures versus staples for skin closure after open gastrointestinal surgery: a phase 3, multicentre, open-label, randomised controlled trial. Lancet (2013) 2.14
Defined factors induce reprogramming of gastrointestinal cancer cells. Proc Natl Acad Sci U S A (2009) 2.11
Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion. Hum Mol Genet (2004) 2.10
Nonpolypoid neoplastic lesions of the colorectal mucosa. Gastrointest Endosc (2008) 2.09
Laparoscopy-assisted hybrid left-side donor hepatectomy. World J Surg (2013) 2.02
A Japanese Lung Cancer Registry study: prognosis of 13,010 resected lung cancers. J Thorac Oncol (2008) 2.01
The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma. J Hepatol (2010) 2.00
Glycine/Serine polymorphism at position 38 influences KCNE1 subunit's modulatory actions on rapid and slow delayed rectifier K+ currents. Circ J (2014) 1.99
Usefulness and safety of bepridil in converting persistent atrial fibrillation to sinus rhythm. Am J Cardiol (2003) 1.98
The Creb1 coactivator Crtc1 is required for energy balance and fertility. Nat Med (2008) 1.87
The novel gene encoding a putative transmembrane protein is mutated in gnathodiaphyseal dysplasia (GDD). Am J Hum Genet (2004) 1.86
Natural history of transthyretin Val30Met familial amyloid polyneuropathy: analysis of late-onset cases from non-endemic areas. J Neurol Neurosurg Psychiatry (2012) 1.81
FGF3/FGF4 amplification and multiple lung metastases in responders to sorafenib in hepatocellular carcinoma. Hepatology (2013) 1.81
Recessive mutations in the putative calcium-activated chloride channel Anoctamin 5 cause proximal LGMD2L and distal MMD3 muscular dystrophies. Am J Hum Genet (2010) 1.81
Clinical significance of the expression of long non-coding RNA HOTAIR in primary hepatocellular carcinoma. Oncol Rep (2012) 1.81
Tranilast attenuates myocardial fibrosis in association with suppression of monocyte/macrophage infiltration in DOCA/salt hypertensive rats. J Hypertens (2004) 1.79
Diagnosis and treatment of deep pulmonary laceration with intrathoracic hemorrhage from blunt trauma. Ann Thorac Surg (2010) 1.77
CD133+CD44+ population efficiently enriches colon cancer initiating cells. Ann Surg Oncol (2008) 1.76
Present status of anticoagulation treatment in Japanese patients with atrial fibrillation: a report from the J-RHYTHM Registry. Circ J (2011) 1.75
Expression of chemokine receptor CCR7 is associated with lymph node metastasis of gastric carcinoma. Cancer Res (2002) 1.75
Remote triggering of deep earthquakes in the 2002 Tonga sequences. Nature (2003) 1.74
Clinical significance of high mobility group A2 in human gastric cancer and its relationship to let-7 microRNA family. Clin Cancer Res (2008) 1.73
Influence of bursectomy on operative morbidity and mortality after radical gastrectomy for gastric cancer: results of a randomized controlled trial. World J Surg (2011) 1.70
Usefulness of combined fractional anisotropy and apparent diffusion coefficient values for detection of involvement in multiple system atrophy. J Neurol Neurosurg Psychiatry (2007) 1.69
A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease. Nat Genet (2005) 1.69
Randomized, multicenter, warfarin-controlled phase II study of edoxaban in Japanese patients with non-valvular atrial fibrillation. Circ J (2012) 1.67
MicroRNA-125a-5p is an independent prognostic factor in gastric cancer and inhibits the proliferation of human gastric cancer cells in combination with trastuzumab. Clin Cancer Res (2011) 1.66
A risk model for esophagectomy using data of 5354 patients included in a Japanese nationwide web-based database. Ann Surg (2014) 1.65
Randomized trial of angiotensin II-receptor blocker vs. dihydropiridine calcium channel blocker in the treatment of paroxysmal atrial fibrillation with hypertension (J-RHYTHM II study). Europace (2010) 1.63
Biological and genetic characteristics of tumor-initiating cells in colon cancer. Ann Surg Oncol (2007) 1.62
Genetic alterations of the tumor suppressor gene WWOX in esophageal squamous cell carcinoma. Cancer Res (2002) 1.62
Clinical significance of TROP2 expression in colorectal cancer. Clin Cancer Res (2006) 1.61
Treatment and prognosis of brain metastases from breast cancer. J Neurooncol (2007) 1.61
Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity. Proc Natl Acad Sci U S A (2010) 1.60
Diameter of splenic vein is a risk factor for portal or splenic vein thrombosis after laparoscopic splenectomy. Surgery (2009) 1.60
Overexpression of miR-200c induces chemoresistance in esophageal cancers mediated through activation of the Akt signaling pathway. Clin Cancer Res (2011) 1.59
Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis. Ann Neurol (2005) 1.59
Optimal treatment strategy for patients with paroxysmal atrial fibrillation: J-RHYTHM Study. Circ J (2008) 1.57
Natural history of spinal and bulbar muscular atrophy (SBMA): a study of 223 Japanese patients. Brain (2006) 1.57
SCRN1 is a novel marker for prognosis in colorectal cancer. J Surg Oncol (2010) 1.57
Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD1. J Biol Chem (2007) 1.57
Neoadjuvant intraperitoneal and systemic chemotherapy for gastric cancer patients with peritoneal dissemination. Ann Surg Oncol (2011) 1.57