Published in Environ Toxicol Chem on April 01, 2005
Designing Endocrine Disruption Out of the Next Generation of Chemicals. Green Chem (2013) 2.47
Interactions between chemical and climate stressors: a role for mechanistic toxicology in assessing climate change risks. Environ Toxicol Chem (2013) 1.07
Modeling human neurodevelopmental disorders in the Xenopus tadpole: from mechanisms to therapeutic targets. Dis Model Mech (2013) 0.91
Thyroid Hormone-disrupting Effects and the Amphibian Metamorphosis Assay. J Toxicol Pathol (2012) 0.78
Developmental timing of perchlorate exposure alters threespine stickleback dermal bone. Gen Comp Endocrinol (2015) 0.78
Surface water mitigates the anti-metamorphic effects of elevated perchlorate concentrations in New Mexico spadefoot toad larvae (Spea multiplicata). Environ Sci Pollut Res Int (2017) 0.75
Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial. Lancet (2002) 14.14
Infliximab maintenance therapy for fistulizing Crohn's disease. N Engl J Med (2004) 6.77
Adalimumab induces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis. Gastroenterology (2011) 5.38
Comparison of scheduled and episodic treatment strategies of infliximab in Crohn's disease. Gastroenterology (2004) 4.26
Natalizumab for the treatment of active Crohn's disease: results of the ENCORE Trial. Gastroenterology (2007) 3.32
Scheduled maintenance treatment with infliximab is superior to episodic treatment for the healing of mucosal ulceration associated with Crohn's disease. Gastrointest Endosc (2006) 2.73
Adalimumab induces and maintains mucosal healing in patients with Crohn's disease: data from the EXTEND trial. Gastroenterology (2012) 2.03
Best practices for use of historical control data of proliferative rodent lesions. Toxicol Pathol (2009) 1.79
Tacrolimus for the treatment of fistulas in patients with Crohn's disease: a randomized, placebo-controlled trial. Gastroenterology (2003) 1.70
Placental transfer of anti-tumor necrosis factor agents in pregnant patients with inflammatory bowel disease. Clin Gastroenterol Hepatol (2012) 1.57
Effects of the androgenic growth promoter 17-beta-trenbolone on fecundity and reproductive endocrinology of the fathead minnow. Environ Toxicol Chem (2003) 1.45
Comparison of ELISAs for detecting vitellogenin in the fathead minnow (Pimephales promelas). Comp Biochem Physiol C Toxicol Pharmacol (2003) 1.44
Quality indicators for inflammatory bowel disease: development of process and outcome measures. Inflamm Bowel Dis (2013) 1.33
Certolizumab pegol in patients with moderate to severe Crohn's disease and secondary failure to infliximab. Clin Gastroenterol Hepatol (2010) 1.19
Assessment of the risk of solar ultraviolet radiation to amphibians. I. Dose-dependent induction of hindlimb malformations in the northern leopard frog (Rana pipiens). Environ Sci Technol (2002) 1.14
Toxicogenomics in regulatory ecotoxicology. Environ Sci Technol (2006) 1.11
A 21st century roadmap for human health risk assessment. Crit Rev Toxicol (2014) 1.07
Cloning and in vitro expression and characterization of the androgen receptor and isolation of estrogen receptor alpha from the fathead Minnow (Pimephales promelas). Environ Sci Technol (2004) 0.97
Risk assessment in the 21st century: roadmap and matrix. Crit Rev Toxicol (2014) 0.95
Evaluation of the aromatase inhibitor fadrozole in a short-term reproduction assay with the fathead minnow (Pimephales promelas). Toxicol Sci (2002) 0.94
Use of the spontaneous Tsc2 knockout (Eker) rat model of hereditary renal cell carcinoma for the study of renal carcinogens. Toxicol Pathol (2003) 0.94
Gene profiling in the livers of wild-type and PPARalpha-null mice exposed to perfluorooctanoic acid. Toxicol Pathol (2008) 0.93
Reproductive and developmental toxicity of arsenic in rodents: a review. Int J Toxicol (2006) 0.92
Coordinated changes in xenobiotic metabolizing enzyme gene expression in aging male rats. Toxicol Sci (2008) 0.91
Atrazine-induced reproductive tract alterations after transplacental and/or lactational exposure in male Long-Evans rats. Toxicol Appl Pharmacol (2006) 0.90
Disruption of testosterone homeostasis as a mode of action for the reproductive toxicity of triazole fungicides in the male rat. Toxicol Sci (2006) 0.90
Genotyping sex in the amphibian, Xenopus (Silurana) tropicalis, for endocrine disruptor bioassays. Aquat Toxicol (2010) 0.89
Pilot feasibility studies of leukocytapheresis with the Adacolumn Apheresis System in patients with active ulcerative colitis or Crohn disease. J Clin Gastroenterol (2006) 0.89
Gene expression profiling of responses to dimethylarsinic acid in female F344 rat urothelium. Toxicology (2005) 0.87
Identification and characterization of adverse effects in 21st century toxicology. Toxicol Sci (2012) 0.87
Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator. Crit Rev Toxicol (2013) 0.86
Developmental toxicity of methoprene and several degradation products in Xenopus laevis. Aquat Toxicol (2003) 0.86
Characterization of responses to the antiandrogen flutamide in a short-term reproduction assay with the fathead minnow. Aquat Toxicol (2004) 0.85
A tiered approach to systemic toxicity testing for agricultural chemical safety assessment. Crit Rev Toxicol (2006) 0.85
Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay. Part 1. Effects on the brain. Aquat Toxicol (2007) 0.85
The effect of chronic progressive nephropathy on the incidence of renal tubule cell neoplasms in control male F344 rats. Toxicol Pathol (2003) 0.85
Transcriptional profile of diuron-induced toxicity on the urinary bladder of male Wistar rats to inform mode of action. Toxicol Sci (2011) 0.84
Progress towards development of an amphibian-based thyroid screening assay using Xenopus laevis. Organismal and thyroidal responses to the model compounds 6-propylthiouracil, methimazole, and thyroxine. Toxicol Sci (2005) 0.84
A data-based assessment of alternative strategies for identification of potential human cancer hazards. Toxicol Pathol (2009) 0.83
Cross-species sensitivity to a novel androgen receptor agonist of potential environmental concern, spironolactone. Environ Toxicol Chem (2013) 0.83
Reproductive maturation of the tropical clawed frog: Xenopus tropicalis. Gen Comp Endocrinol (2008) 0.83
Effects of prenatal exposure to a low dose atrazine metabolite mixture on pubertal timing and prostate development of male Long-Evans rats. Reprod Toxicol (2010) 0.83
Sex reversal of the amphibian, Xenopus tropicalis, following larval exposure to an aromatase inhibitor. Aquat Toxicol (2008) 0.83
Propiconazole-induced cytochrome P450 gene expression and enzymatic activities in rat and mouse liver. Toxicol Lett (2005) 0.82
What do we need to know prior to thinking about incorporating an epigenetic evaluation into safety assessments? Toxicol Sci (2010) 0.82
Use of multi-photon laser-scanning microscopy to describe the distribution of xenobiotic chemicals in fish early life stages. Aquat Toxicol (2004) 0.82
Oxidative DNA damage from potassium bromate exposure in Long-Evans rats is not enhanced by a mixture of drinking water disinfection by-products. Chem Biol Interact (2005) 0.81
Evaluation of gene expression endpoints in the context of a Xenopus laevis metamorphosis-based bioassay to detect thyroid hormone disruptors. Aquat Toxicol (2005) 0.81
Gene expression profiling in the liver of CD-1 mice to characterize the hepatotoxicity of triazole fungicides. Toxicol Appl Pharmacol (2006) 0.81
Tissue distribution and urinary excretion of dimethylated arsenic and its metabolites in dimethylarsinic acid- or arsenate-treated rats. Toxicol Appl Pharmacol (2007) 0.81
Mechanistic basis for estrogenic effects in fathead minnow (Pimephales promelas) following exposure to the androgen 17alpha-methyltestosterone: conversion of 17alpha-methyltestosterone to 17alpha-methylestradiol. Aquat Toxicol (2004) 0.80
Effect of conazole fungicides on reproductive development in the female rat. Reprod Toxicol (2006) 0.80
Gene expression profiling in liver and testis of rats to characterize the toxicity of triazole fungicides. Toxicol Appl Pharmacol (2006) 0.80
Thyroid histopathology assessments for the amphibian metamorphosis assay to detect thyroid-active substances. Toxicol Pathol (2009) 0.80
Transcriptional profiles in liver from mice treated with hepatotumorigenic and nonhepatotumorigenic triazole conazole fungicides: Propiconazole, triadimefon, and myclobutanil. Toxicol Pathol (2006) 0.80
Identification of interspecies concordance of mechanisms of arsenic-induced bladder cancer. Toxicol In Vitro (2007) 0.80
A randomised, double-blind, sham-controlled study of granulocyte/monocyte apheresis for moderate to severe Crohn's disease. Gut (2012) 0.79
Formaldehyde-induced gene expression in F344 rat nasal respiratory epithelium. Toxicology (2003) 0.79
Early temporal effects of three thyroid hormone synthesis inhibitors in Xenopus laevis. Aquat Toxicol (2010) 0.79
Toxicity profiles in mice treated with hepatotumorigenic and non-hepatotumorigenic triazole conazole fungicides: Propiconazole, triadimefon, and myclobutanil. Toxicol Pathol (2006) 0.79
Methanol exposure during gastrulation causes holoprosencephaly, facial dysgenesis, and cervical vertebral malformations in C57BL/6J mice. Birth Defects Res B Dev Reprod Toxicol (2004) 0.79
Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay. Part 2. Effects on the tail and hindlimb. Aquat Toxicol (2007) 0.79
Potential for a global historical control database for proliferative rodent lesions. Toxicol Pathol (2009) 0.79
Crohn's colitis presenting with node-negative colon cancer and liver metastasis after therapy with infliximab: report of two cases. Dis Colon Rectum (2005) 0.78
Induction of transitional cell hyperplasia in the urinary bladder and aberrant crypt foci in the colon of rats treated with individual and a mixture of drinking water disinfection by-products. Toxicol Pathol (2003) 0.78
Comparing the effects of stage and duration of retinoic Acid exposure on amphibian limb development: chronic exposure results in mortality, not limb malformations. Toxicol Sci (2003) 0.78
Inhibition of thyroid hormone release from cultured amphibian thyroid glands by methimazole, 6-propylthiouracil, and perchlorate. Toxicol Sci (2010) 0.78
Transcriptional profiles in liver from rats treated with tumorigenic and non-tumorigenic triazole conazole fungicides: Propiconazole, triadimefon, and myclobutanil. Toxicol Pathol (2006) 0.78
In vivo assessment and potential diagnosis of xenobiotics that perturb the thyroid pathway: Proteomic analysis of Xenopus laevis brain tissue following exposure to model T4 inhibitors. Comp Biochem Physiol Part D Genomics Proteomics (2010) 0.78
Development of quantitative real-time PCR assays for fathead minnow (Pimephales promelas) gonadotropin beta subunit mRNAs to support endocrine disruptor research. Comp Biochem Physiol C Toxicol Pharmacol (2006) 0.78
Thyroid-stimulating hormone (TSH): measurement of intracellular, secreted, and circulating hormone in Xenopus laevis and Xenopus tropicalis. Gen Comp Endocrinol (2011) 0.78
Dimethylarsinic acid in drinking water changed the morphology of urinary bladder but not the expression of DNA repair genes of bladder transitional epithelium in F344 rats. Toxicol Pathol (2009) 0.78
Fluconazole-induced hepatic cytochrome P450 gene expression and enzymatic activities in rats and mice. Toxicol Lett (2006) 0.78
Analysis of preneoplastic and neoplastic renal lesions in Tsc2 mutant Long-Evans (Eker) rats following exposure to a mixture of drinking water disinfection by-products. Toxicology (2003) 0.77
Trenbolone causes mortality and altered sexual differentiation in Xenopus tropicalis during larval development. Environ Toxicol Chem (2012) 0.77