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1
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Early clinical PET imaging results with the novel PHF-tau radioligand [F-18]-T807.
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J Alzheimers Dis
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2013
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3.10
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2
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Multistep synthesis of a radiolabeled imaging probe using integrated microfluidics.
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Science
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2005
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2.83
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3
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[(18)F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease.
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Alzheimers Dement
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2013
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2.31
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4
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The clinical importance of assessing tumor hypoxia: relationship of tumor hypoxia to prognosis and therapeutic opportunities.
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Antioxid Redox Signal
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2014
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2.26
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5
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"On water": unique reactivity of organic compounds in aqueous suspension.
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Angew Chem Int Ed Engl
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2005
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2.21
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6
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Inhibitors of HIV-1 protease by using in situ click chemistry.
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Angew Chem Int Ed Engl
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2006
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1.63
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7
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In situ click chemistry: enzyme inhibitors made to their own specifications.
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J Am Chem Soc
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2004
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1.61
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8
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A highly selective and specific PET tracer for imaging of tau pathologies.
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J Alzheimers Dis
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2012
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1.56
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9
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Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation.
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Proc Natl Acad Sci U S A
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2004
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1.52
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10
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In situ selection of lead compounds by click chemistry: target-guided optimization of acetylcholinesterase inhibitors.
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J Am Chem Soc
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2005
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1.47
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11
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Early clinical PET imaging results with the novel PHF-tau radioligand [F18]-T808.
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J Alzheimers Dis
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2014
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1.36
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12
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In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II.
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Angew Chem Int Ed Engl
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2004
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1.35
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13
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Integrated microfluidics for parallel screening of an in situ click chemistry library.
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Angew Chem Int Ed Engl
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2006
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1.24
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14
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Biodistribution and radiation dosimetry of the integrin marker 18F-RGD-K5 determined from whole-body PET/CT in monkeys and humans.
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J Nucl Med
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2012
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1.18
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15
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Design and optimization of coin-shaped microreactor chips for PET radiopharmaceutical synthesis.
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J Nucl Med
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2010
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1.05
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16
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¹⁸F-HX4 hypoxia imaging with PET/CT in head and neck cancer: a comparison with ¹⁸F-FMISO.
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Nucl Med Commun
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2012
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1.02
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17
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Preclinical evaluation and validation of [18F]HX4, a promising hypoxia marker for PET imaging.
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Proc Natl Acad Sci U S A
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2011
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0.98
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18
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Batch-reactor microfluidic device: first human use of a microfluidically produced PET radiotracer.
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Lab Chip
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2012
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0.97
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19
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An integrated microfluidic device for large-scale in situ click chemistry screening.
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Lab Chip
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2009
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0.95
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20
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Biodistribution and radiation dosimetry of the hypoxia marker 18F-HX4 in monkeys and humans determined by using whole-body PET/CT.
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Nucl Med Commun
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2010
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0.90
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21
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Structural insights into conformational flexibility at the peripheral site and within the active center gorge of AChE.
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Chem Biol Interact
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2005
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0.86
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22
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Evaluation of [(18)F]-CP18 as a PET imaging tracer for apoptosis.
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Mol Imaging Biol
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2013
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0.85
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23
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Applications of click chemistry in radiopharmaceutical development.
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Chimia (Aarau)
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2010
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0.84
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24
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In vitro and in vivo evaluation of the caspase-3 substrate-based radiotracer [(18)F]-CP18 for PET imaging of apoptosis in tumors.
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Mol Imaging Biol
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2013
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0.83
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25
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Flow optimization study of a batch microfluidics PET tracer synthesizing device.
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Biomed Microdevices
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2011
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0.82
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26
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Biodistribution and radiation dosimetry of 18F-CP-18, a potential apoptosis imaging agent, as determined from PET/CT scans in healthy volunteers.
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J Nucl Med
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2013
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0.81
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27
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Biodistribution and radiation dosimetry of the carbonic anhydrase IX imaging agent [(18) F]VM4-037 determined from PET/CT scans in healthy volunteers.
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Mol Imaging Biol
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2014
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0.81
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28
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Pre-clinical evaluation of a 3-nitro-1,2,4-triazole analogue of [18F]FMISO as hypoxia-selective tracer for PET.
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Nucl Med Biol
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2010
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0.80
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29
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The synthesis of azadirachtin: a potent insect antifeedant.
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Chemistry
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2008
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0.78
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30
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From in situ to in vivo: an in situ click-chemistry-derived carbonic anhydrase II imaging agent for positron emission tomography.
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ChemMedChem
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2012
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0.77
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31
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Atherosclerotic plaque uptake of a novel integrin tracer ¹⁸F-Flotegatide in a mouse model of atherosclerosis.
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J Nucl Cardiol
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2014
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0.77
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