Published in Angew Chem Int Ed Engl on May 20, 2005
Zn-mediated, Pd-catalyzed cross-couplings in water at room temperature without prior formation of organozinc reagents. J Am Chem Soc (2009) 1.86
Green chemistry for chemical synthesis. Proc Natl Acad Sci U S A (2008) 1.56
Organic synthesis "on water". Chem Rev (2009) 1.37
Strategic redox relay enables a scalable synthesis of ouabagenin, a bioactive cardenolide. Science (2013) 1.35
Enzymatic basis of ribosomal peptide prenylation in cyanobacteria. J Am Chem Soc (2011) 1.25
"Designer"-Surfactant-Enabled Cross-Couplings in Water at Room Temperature. Aldrichimica Acta (2012) 1.22
On the synergism between H2O and a tetrahydropyran template in the regioselective cyclization of an epoxy alcohol. J Am Chem Soc (2009) 1.17
Manipulating micellar environments for enhancing transition metal-catalyzed cross-couplings in water at room temperature. J Org Chem (2011) 1.13
Reactions of nitroso hetero-Diels-Alder cycloadducts with azides: stereoselective formation of triazolines and aziridines. J Org Chem (2007) 0.98
C-C bond formation via copper-catalyzed conjugate addition reactions to enones in water at room temperature. J Am Chem Soc (2012) 0.94
Development of a concise synthesis of ouabagenin and hydroxylated corticosteroid analogues. J Am Chem Soc (2015) 0.90
Diels-Alder cycloadditions in water for the straightforward preparation of peptide-oligonucleotide conjugates. Nucleic Acids Res (2006) 0.87
Imines that react with phenols in water over a wide pH range. J Org Chem (2008) 0.85
A versatile method for the preparation of conjugates of peptides with DNA/PNA/analog by employing chemo-selective click reaction in water. Nucleic Acids Res (2007) 0.85
A bioorthogonal quadricyclane ligation. J Am Chem Soc (2011) 0.85
Miyaura Borylations of Aryl Bromides in Water at Room Temperature. Isr J Chem (2010) 0.83
(+/-)-(1S,2R,5S)-5-Amino-2-fluorocyclohex-3-enecarboxylic acid. A potent GABA aminotransferase inactivator that irreversibly inhibits via an elimination-aromatization pathway. Biochemistry (2006) 0.83
Entropic factors provide unusual reactivity and selectivity in epoxide-opening reactions promoted by water. Proc Natl Acad Sci U S A (2013) 0.82
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue. J Am Chem Soc (2016) 0.81
Amination of heteroaryl chlorides: palladium catalysis or SN Ar in green solvents? ChemSusChem (2013) 0.81
Chemoselective immobilization of biomolecules through aqueous Diels-Alder and PEG chemistry. Tetrahedron Lett (2008) 0.80
Quantum and Molecular Mechanical (QM/MM) Monte Carlo Techniques for Modeling Condensed-Phase Reactions. Wiley Interdiscip Rev Comput Mol Sci (2014) 0.79
Transitioning organic synthesis from organic solvents to water. What's your E Factor? Green Chem (2014) 0.79
Remarkable facilitation of hetero-cycloisomerizations with water and other polar protic solvents: metal-free synthesis of indolizines. Green Chem (2010) 0.79
A palladium nanoparticle-nanomicelle combination for the stereoselective semihydrogenation of alkynes in water at room temperature. Angew Chem Int Ed Engl (2014) 0.78
Photochemical oxidation of water and reduction of polyoxometalate anions at interfaces of water with ionic liquids or diethylether. Proc Natl Acad Sci U S A (2012) 0.78
Decreasing Distortion Energies without Strain: Diazo-Selective 1,3-Dipolar Cycloadditions. J Org Chem (2016) 0.78
Palladium(0) catalyzed 2,2'-bipyrrole syntheses. J Porphyr Phthalocyanines (2011) 0.78
Ordered polyelectrolyte assembly at the oil-water interface. Proc Natl Acad Sci U S A (2012) 0.78
Acceleration of an aromatic Claisen rearrangement via a designed spiroligozyme catalyst that mimics the ketosteroid isomerase catalytic dyad. J Am Chem Soc (2014) 0.77
Quantum mechanical/molecular mechanical modeling finds Diels-Alder reactions are accelerated less on the surface of water than in water. J Am Chem Soc (2010) 0.77
Mechanism of vibrational energy dissipation of free OH groups at the air-water interface. Proc Natl Acad Sci U S A (2013) 0.77
Aromatic Claisen Rearrangements of O-prenylated tyrosine and model prenyl aryl ethers: Computational study of the role of water on acceleration of Claisen rearrangements. European J Org Chem (2013) 0.76
Mechanistic Insights into Two-Phase Radical C-H Arylations. ACS Cent Sci (2015) 0.75
1,3-Dipolar Cycloaddition with Diazo Groups: Noncovalent Interactions Overwhelm Strain. Org Lett (2016) 0.75
"On-water" catalyst-free ecofriendly synthesis of the hantzsch dihydropyridines. ISRN Org Chem (2012) 0.75
Regioselective synthesis of N-beta-hydroxyethylaziridines by the ring-opening reaction of epoxides with aziridine generated in situ. Org Lett (2006) 0.75
A unifying paradigm for naphthoquinone-based meroterpenoid (bio)synthesis. Nat Chem (2017) 0.75
Fine-Tuning Strain and Electronic Activation of Strain-Promoted 1,3-Dipolar Cycloadditions with Endocyclic Sulfamates in SNO-OCTs. J Am Chem Soc (2017) 0.75
Recent Advances in Inverse-Electron-Demand Hetero-Diels-Alder Reactions of 1-Oxa-1,3-Butadienes. Top Curr Chem (J) (2016) 0.75
Fischer Indole Synthesis in the Gas Phase, the Solution Phase, and at the Electrospray Droplet Interface. J Am Soc Mass Spectrom (2017) 0.75
Acceleration of Batch-type Heterogeneous Ligand-free Suzuki-Miyaura Reactions with Polymer Composite Supported Pd Catalyst. Sci Rep (2017) 0.75
A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes. Angew Chem Int Ed Engl (2002) 24.12
The growing impact of click chemistry on drug discovery. Drug Discov Today (2003) 6.79
Polytriazoles as copper(I)-stabilizing ligands in catalysis. Org Lett (2004) 5.49
Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition. J Am Chem Soc (2003) 5.34
Clinical Risk Groups (CRGs): a classification system for risk-adjusted capitation-based payment and health care management. Med Care (2004) 3.98
Analysis and optimization of copper-catalyzed azide-alkyne cycloaddition for bioconjugation. Angew Chem Int Ed Engl (2009) 3.81
Early clinical PET imaging results with the novel PHF-tau radioligand [F-18]-T807. J Alzheimers Dis (2013) 3.10
Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks. Angew Chem Int Ed Engl (2002) 3.06
A closer look at all-patient refined DRGs. J AHIMA (2002) 3.05
Multistep synthesis of a radiolabeled imaging probe using integrated microfluidics. Science (2005) 2.83
Copper(I)-catalyzed synthesis of azoles. DFT study predicts unprecedented reactivity and intermediates. J Am Chem Soc (2005) 2.75
Copper-catalyzed azide-alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper(I) acetylides. Chem Soc Rev (2010) 2.68
Mechanism of the ligand-free CuI-catalyzed azide-alkyne cycloaddition reaction. Angew Chem Int Ed Engl (2005) 2.62
Identifying potentially preventable complications using a present on admission indicator. Health Care Financ Rev (2006) 2.52
Ruthenium-catalyzed cycloaddition of alkynes and organic azides. J Am Chem Soc (2005) 2.35
[(18)F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease. Alzheimers Dement (2013) 2.31
The clinical importance of assessing tumor hypoxia: relationship of tumor hypoxia to prognosis and therapeutic opportunities. Antioxid Redox Signal (2014) 2.26
Efficiency and fidelity in a click-chemistry route to triazole dendrimers by the copper(i)-catalyzed ligation of azides and alkynes. Angew Chem Int Ed Engl (2004) 2.11
Copper(I)-catalyzed cycloaddition of organic azides and 1-iodoalkynes. Angew Chem Int Ed Engl (2009) 2.10
Discovery and characterization of catalysts for azide-alkyne cycloaddition by fluorescence quenching. J Am Chem Soc (2004) 1.89
Rhodium-catalyzed transannulation of 1,2,3-triazoles with nitriles. J Am Chem Soc (2008) 1.86
Labeling live cells by copper-catalyzed alkyne--azide click chemistry. Bioconjug Chem (2010) 1.86
Rhodium-catalyzed enantioselective cyclopropanation of olefins with N-sulfonyl 1,2,3-triazoles. J Am Chem Soc (2009) 1.85
Accelerated bioorthogonal conjugation: a practical method for the ligation of diverse functional molecules to a polyvalent virus scaffold. Bioconjug Chem (2005) 1.84
Ruthenium-catalyzed azide-alkyne cycloaddition: scope and mechanism. J Am Chem Soc (2008) 1.76
Ligand-accelerated Cu-catalyzed azide-alkyne cycloaddition: a mechanistic report. J Am Chem Soc (2007) 1.72
A heteroaryldihydropyrimidine activates and can misdirect hepatitis B virus capsid assembly. Proc Natl Acad Sci U S A (2005) 1.72
Folic acid-mediated targeting of cowpea mosaic virus particles to tumor cells. Chem Biol (2007) 1.70
A sulfilimine bond identified in collagen IV. Science (2009) 1.69
Profile of medical charges for children by health status group and severity level in a Washington State Health Plan. Health Serv Res (2004) 1.68
Label-free quantification of membrane-ligand interactions using backscattering interferometry. Nat Biotechnol (2011) 1.67
Iterative in situ click chemistry creates antibody-like protein-capture agents. Angew Chem Int Ed Engl (2009) 1.64
Natural supramolecular building blocks. Wild-type cowpea mosaic virus. Chem Biol (2002) 1.64
Viral MRI contrast agents: coordination of Gd by native virions and attachment of Gd complexes by azide-alkyne cycloaddition. Chem Commun (Camb) (2007) 1.63
Inhibitors of HIV-1 protease by using in situ click chemistry. Angew Chem Int Ed Engl (2006) 1.63
In situ click chemistry: enzyme inhibitors made to their own specifications. J Am Chem Soc (2004) 1.61
Global structural changes in hepatitis B virus capsids induced by the assembly effector HAP1. J Virol (2006) 1.59
A highly selective and specific PET tracer for imaging of tau pathologies. J Alzheimers Dis (2012) 1.56
Tailored ligand acceleration of the Cu-catalyzed azide-alkyne cycloaddition reaction: practical and mechanistic implications. J Am Chem Soc (2010) 1.56
Designing facial amphiphiles for the stabilization of integral membrane proteins. Angew Chem Int Ed Engl (2007) 1.55
Crosslinking of and coupling to viral capsid proteins by tyrosine oxidation. Chem Biol (2004) 1.55
Unnatural amino acid incorporation into virus-like particles. Bioconjug Chem (2008) 1.54
Systemic trafficking of plant virus nanoparticles in mice via the oral route. Virology (2005) 1.53
Bio-distribution, toxicity and pathology of cowpea mosaic virus nanoparticles in vivo. J Control Release (2007) 1.53
A potent and highly selective inhibitor of human alpha-1,3-fucosyltransferase via click chemistry. J Am Chem Soc (2003) 1.53
Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation. Proc Natl Acad Sci U S A (2004) 1.52
Benzimidazole and related ligands for Cu-catalyzed azide-alkyne cycloaddition. J Am Chem Soc (2007) 1.50
Identifying and classifying children with chronic conditions using administrative data with the clinical risk group classification system. Ambul Pediatr (2002) 1.49
Icosahedral virus particles as addressable nanoscale building blocks. Angew Chem Int Ed Engl (2002) 1.49
A click chemistry approach to tetrazoles by Huisgen 1,3-dipolar cycloaddition: synthesis of 5-sulfonyl tetrazoles from azides and sulfonyl cyanides. Angew Chem Int Ed Engl (2002) 1.48
In situ selection of lead compounds by click chemistry: target-guided optimization of acetylcholinesterase inhibitors. J Am Chem Soc (2005) 1.47
Synthesis and reactivity of rhodium(II) N-triflyl azavinyl carbenes. J Am Chem Soc (2010) 1.45
Hybrid virus-polymer materials. 1. Synthesis and properties of PEG-decorated cowpea mosaic virus. Biomacromolecules (2003) 1.42
Plasma clearance of bacteriophage Qbeta particles as a function of surface charge. J Am Chem Soc (2008) 1.41
In situ click chemistry: probing the binding landscapes of biological molecules. Chem Soc Rev (2010) 1.38
Organic synthesis "on water". Chem Rev (2009) 1.37
Thiol-selective fluorogenic probes for labeling and release. J Am Chem Soc (2009) 1.36
Early clinical PET imaging results with the novel PHF-tau radioligand [F18]-T808. J Alzheimers Dis (2014) 1.36
In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II. Angew Chem Int Ed Engl (2004) 1.35
Small-molecule effectors of hepatitis B virus capsid assembly give insight into virus life cycle. J Virol (2008) 1.34
Direct human cartilage repair using three-dimensional bioprinting technology. Tissue Eng Part A (2012) 1.33
Multivalent, bifunctional dendrimers prepared by click chemistry. Chem Commun (Camb) (2005) 1.32
Structure and compatibility of a magnesium electrolyte with a sulphur cathode. Nat Commun (2011) 1.30
The allylic azide rearrangement: achieving selectivity. J Am Chem Soc (2005) 1.30
Functional virus-based polymer-protein nanoparticles by atom transfer radical polymerization. J Am Chem Soc (2011) 1.30
Natural supramolecular building blocks. Cysteine-added mutants of cowpea mosaic virus. Chem Biol (2002) 1.29
Practical synthesis of amides from in situ generated copper(I) acetylides and sulfonyl azides. Angew Chem Int Ed Engl (2006) 1.29
Chemical modification of viruses and virus-like particles. Curr Top Microbiol Immunol (2009) 1.28
Core-clickable PEG-branch-azide bivalent-bottle-brush polymers by ROMP: grafting-through and clicking-to. J Am Chem Soc (2010) 1.26
On-virus construction of polyvalent glycan ligands for cell-surface receptors. J Am Chem Soc (2008) 1.26
Integrated microfluidics for parallel screening of an in situ click chemistry library. Angew Chem Int Ed Engl (2006) 1.24
Multivalent display and receptor-mediated endocytosis of transferrin on virus-like particles. Chembiochem (2010) 1.24
Click chemistry: function follows form. Chem Soc Rev (2010) 1.23
Head-to-tail peptide cyclodimerization by copper-catalyzed azide-alkyne cycloaddition. Angew Chem Int Ed Engl (2005) 1.23