Published in Am J Physiol Regul Integr Comp Physiol on April 21, 2005
Molecular mechanisms of BK channel activation. Cell Mol Life Sci (2009) 1.81
Central role of the BK channel in urinary bladder smooth muscle physiology and pathophysiology. Am J Physiol Regul Integr Comp Physiol (2014) 1.76
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Suppression of human detrusor smooth muscle excitability and contractility via pharmacological activation of large conductance Ca2+-activated K+ channels. Am J Physiol Cell Physiol (2012) 1.20
{beta} subunit-specific modulations of BK channel function by a mutation associated with epilepsy and dyskinesia. J Physiol (2009) 1.08
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BK channel activation by NS11021 decreases excitability and contractility of urinary bladder smooth muscle. Am J Physiol Regul Integr Comp Physiol (2009) 1.03
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Nerve-evoked purinergic signalling suppresses action potentials, Ca2+ flashes and contractility evoked by muscarinic receptor activation in mouse urinary bladder smooth muscle. J Physiol (2009) 1.01
Small-conductance, Ca(2+) -activated K+ channel 2 is the key functional component of SK channels in mouse urinary bladder. Am J Physiol Regul Integr Comp Physiol (2008) 0.99
SK but not IK channels regulate human detrusor smooth muscle spontaneous and nerve-evoked contractions. Am J Physiol Renal Physiol (2012) 0.99
Functional expression of SK channels in murine detrusor PDGFR+ cells. J Physiol (2012) 0.96
Do β3-adrenergic receptors play a role in guinea pig detrusor smooth muscle excitability and contractility? Am J Physiol Renal Physiol (2011) 0.94
NFATc3 regulates BK channel function in murine urinary bladder smooth muscle. Am J Physiol Cell Physiol (2008) 0.94
Effects of bladder outlet obstruction on properties of Ca2+-activated K+ channels in rat bladder. Am J Physiol Regul Integr Comp Physiol (2010) 0.94
Unique properties of muscularis mucosae smooth muscle in guinea pig urinary bladder. Am J Physiol Regul Integr Comp Physiol (2011) 0.90
Ca2+-sparks constitute elementary building blocks for global Ca2+-signals in myocytes of retinal arterioles. Cell Calcium (2006) 0.88
Nerve-released acetylcholine contracts urinary bladder smooth muscle by inducing action potentials independently of IP3-mediated calcium release. Am J Physiol Regul Integr Comp Physiol (2010) 0.87
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Smooth muscle and neural mechanisms contributing to the downregulation of neonatal rat spontaneous bladder contractions during postnatal development. Am J Physiol Regul Integr Comp Physiol (2007) 0.84
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Adjustable passive stiffness in mouse bladder: regulated by Rho kinase and elevated following partial bladder outlet obstruction. Am J Physiol Renal Physiol (2011) 0.81
Role of neuronal voltage-gated K(+) channels in the modulation of the nitrergic neurotransmission of the pig urinary bladder neck. Br J Pharmacol (2008) 0.80
5-hydroxytryptamine induced relaxation in the pig urinary bladder neck. Br J Pharmacol (2009) 0.78
NS19504: a novel BK channel activator with relaxing effect on bladder smooth muscle spontaneous phasic contractions. J Pharmacol Exp Ther (2014) 0.78
Involvement of a membrane potassium channel in heparan sulphate-induced activation of macrophages. Immunology (2014) 0.78
Detection of renal tissue and urinary tract proteins in the human urine after space flight. PLoS One (2013) 0.78
Modulation of purinergic neuromuscular transmission by phorbol dibutyrate is independent of protein kinase C in murine urinary bladder. J Pharmacol Exp Ther (2012) 0.77
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Local potassium signaling couples neuronal activity to vasodilation in the brain. Nat Neurosci (2006) 3.27
Calcium-activated potassium channels and the regulation of vascular tone. Physiology (Bethesda) (2006) 3.25
TRPV4 forms a novel Ca2+ signaling complex with ryanodine receptors and BKCa channels. Circ Res (2005) 3.22
Overactive bladder and incontinence in the absence of the BK large conductance Ca2+-activated K+ channel. J Biol Chem (2004) 2.96
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Elementary Ca2+ signals through endothelial TRPV4 channels regulate vascular function. Science (2012) 2.48
Functional architecture of inositol 1,4,5-trisphosphate signaling in restricted spaces of myoendothelial projections. Proc Natl Acad Sci U S A (2008) 2.47
Altered expression of small-conductance Ca2+-activated K+ (SK3) channels modulates arterial tone and blood pressure. Circ Res (2003) 2.25
Calcium dynamics in cortical astrocytes and arterioles during neurovascular coupling. Circ Res (2004) 2.17
Astrocytic endfoot Ca2+ and BK channels determine both arteriolar dilation and constriction. Proc Natl Acad Sci U S A (2010) 1.90
Modulation of the molecular composition of large conductance, Ca(2+) activated K(+) channels in vascular smooth muscle during hypertension. J Clin Invest (2003) 1.79
Differential regulation of SK and BK channels by Ca(2+) signals from Ca(2+) channels and ryanodine receptors in guinea-pig urinary bladder myocytes. J Physiol (2002) 1.65
Signaling between SR and plasmalemma in smooth muscle: sparks and the activation of Ca2+-sensitive ion channels. Cell Calcium (2003) 1.56
Differential regulation of Ca2+-activated K+ channels by beta-adrenoceptors in guinea pig urinary bladder smooth muscle. Am J Physiol Cell Physiol (2005) 1.54
Functional coupling of calcineurin and protein kinase A in mouse ventricular myocytes. J Physiol (2002) 1.54
High blood pressure arising from a defect in vascular function. Proc Natl Acad Sci U S A (2008) 1.50
Differential patterning of cGMP in vascular smooth muscle cells revealed by single GFP-linked biosensors. Proc Natl Acad Sci U S A (2007) 1.50
Urinary bladder instability induced by selective suppression of the murine small conductance calcium-activated potassium (SK3) channel. J Physiol (2003) 1.48
Ca2+-activated K+ channels in murine endothelial cells: block by intracellular calcium and magnesium. J Gen Physiol (2008) 1.46
Beta-adrenergic relaxation of mouse urinary bladder smooth muscle in the absence of large-conductance Ca2+-activated K+ channel. Am J Physiol Renal Physiol (2008) 1.45
Endothelial SK(Ca) and IK(Ca) channels regulate brain parenchymal arteriolar diameter and cortical cerebral blood flow. J Cereb Blood Flow Metab (2010) 1.44
Erectile dysfunction in mice lacking the large-conductance calcium-activated potassium (BK) channel. J Physiol (2005) 1.43
Ion channels in smooth muscle: regulators of intracellular calcium and contractility. Can J Physiol Pharmacol (2005) 1.41
Elementary purinergic Ca2+ transients evoked by nerve stimulation in rat urinary bladder smooth muscle. J Physiol (2005) 1.36
Fundamental increase in pressure-dependent constriction of brain parenchymal arterioles from subarachnoid hemorrhage model rats due to membrane depolarization. Am J Physiol Heart Circ Physiol (2010) 1.31
Hydrophobic bile salts inhibit gallbladder smooth muscle function via stimulation of GPBAR1 receptors and activation of KATP channels. J Physiol (2010) 1.29
Transient receptor potential (TRP) channels, vascular tone and autoregulation of cerebral blood flow. Clin Exp Pharmacol Physiol (2008) 1.29
Frequency encoding of cholinergic- and purinergic-mediated signaling to mouse urinary bladder smooth muscle: modulation by BK channels. Am J Physiol Regul Integr Comp Physiol (2006) 1.22
Nuclear factor of activated T cells and serum response factor cooperatively regulate the activity of an alpha-actin intronic enhancer. J Biol Chem (2005) 1.21
Morphological and physiological evidence for interstitial cell of Cajal-like cells in the guinea pig gallbladder. J Physiol (2007) 1.20
TRPV4 channels stimulate Ca2+-induced Ca2+ release in astrocytic endfeet and amplify neurovascular coupling responses. Proc Natl Acad Sci U S A (2013) 1.20
Acidosis dilates brain parenchymal arterioles by conversion of calcium waves to sparks to activate BK channels. Circ Res (2011) 1.19
Properties and molecular basis of the mouse urinary bladder voltage-gated K+ current. J Physiol (2003) 1.19
Calcium signaling in smooth muscle. Cold Spring Harb Perspect Biol (2011) 1.19
Shiga toxin 2 affects the central nervous system through receptor globotriaosylceramide localized to neurons. J Infect Dis (2008) 1.16
Dynamic inositol trisphosphate-mediated calcium signals within astrocytic endfeet underlie vasodilation of cerebral arterioles. J Gen Physiol (2006) 1.16
Membrane stretch-induced activation of a TRPM4-like nonselective cation channel in cerebral artery myocytes. J Pharmacol Sci (2007) 1.15
Constitutively elevated nuclear export activity opposes Ca2+-dependent NFATc3 nuclear accumulation in vascular smooth muscle: role of JNK2 and Crm-1. J Biol Chem (2003) 1.14
Intraluminal pressure is a stimulus for NFATc3 nuclear accumulation: role of calcium, endothelium-derived nitric oxide, and cGMP-dependent protein kinase. J Biol Chem (2003) 1.14
Astrocytic calcium signaling: the information currency coupling neuronal activity to the cerebral microcirculation. Trends Cardiovasc Med (2007) 1.12
Opposing actions of inositol 1,4,5-trisphosphate and ryanodine receptors on nuclear factor of activated T-cells regulation in smooth muscle. J Biol Chem (2002) 1.12
Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle. J Gen Physiol (2014) 1.10
Inversion of neurovascular coupling by subarachnoid blood depends on large-conductance Ca2+-activated K+ (BK) channels. Proc Natl Acad Sci U S A (2012) 1.08
NFAT regulation in smooth muscle. Trends Cardiovasc Med (2003) 1.08
Role for pituitary adenylate cyclase activating polypeptide in cystitis-induced plasticity of micturition reflexes. Am J Physiol Regul Integr Comp Physiol (2005) 1.08
Ca2+ sparks and their function in human cerebral arteries. Stroke (2002) 1.06
Potassium channels and neurovascular coupling. Circ J (2010) 1.04
Reduced Ca2+ spark activity after subarachnoid hemorrhage disables BK channel control of cerebral artery tone. J Cereb Blood Flow Metab (2010) 1.03
BK channel activation by NS11021 decreases excitability and contractility of urinary bladder smooth muscle. Am J Physiol Regul Integr Comp Physiol (2009) 1.03
Sympathetic nerve stimulation induces local endothelial Ca2+ signals to oppose vasoconstriction of mouse mesenteric arteries. Am J Physiol Heart Circ Physiol (2011) 1.02
Nerve-evoked purinergic signalling suppresses action potentials, Ca2+ flashes and contractility evoked by muscarinic receptor activation in mouse urinary bladder smooth muscle. J Physiol (2009) 1.01
Role of mitochondria in spontaneous rhythmic activity and intracellular calcium waves in the guinea pig gallbladder smooth muscle. Am J Physiol Gastrointest Liver Physiol (2007) 1.01
Alkaline pH shifts Ca2+ sparks to Ca2+ waves in smooth muscle cells of pressurized cerebral arteries. Am J Physiol Heart Circ Physiol (2002) 1.00
Properties of a tonically active, sodium-permeable current in mouse urinary bladder smooth muscle. Am J Physiol Cell Physiol (2004) 0.99
Deletion of Cx43 from osteocytes results in defective bone material properties but does not decrease extrinsic strength in cortical bone. Calcif Tissue Int (2012) 0.99
Inositol trisphosphate receptor calcium release is required for cerebral artery smooth muscle cell proliferation. Am J Physiol Heart Circ Physiol (2005) 0.96
Spontaneous electrical rhythmicity and the role of the sarcoplasmic reticulum in the excitability of guinea pig gallbladder smooth muscle cells. Am J Physiol Gastrointest Liver Physiol (2005) 0.96
Effect of endogenous and exogenous nitric oxide on calcium sparks as targets for vasodilation in rat cerebral artery. Nitric Oxide (2006) 0.96
Regulation of intracerebral arteriolar tone by K(v) channels: effects of glucose and PKC. Am J Physiol Cell Physiol (2009) 0.95
Mechanisms of enhanced basal tone of brain parenchymal arterioles during early postischemic reperfusion: role of ET-1-induced peroxynitrite generation. J Cereb Blood Flow Metab (2013) 0.95
Endothelial histamine H1 receptor signaling reduces blood-brain barrier permeability and susceptibility to autoimmune encephalomyelitis. Proc Natl Acad Sci U S A (2010) 0.94
Mimicking white matter tract topography using core-shell electrospun nanofibers to examine migration of malignant brain tumors. Biomaterials (2013) 0.93
Osteoblast/osteocyte-specific inactivation of Stat3 decreases load-driven bone formation and accumulates reactive oxygen species. Bone (2011) 0.92
Novel PPARgamma agonists GI 262570, GW 7845, GW 1929, and pioglitazone decrease calcium channel function and myogenic tone in rat mesenteric arteries. Pharmacology (2004) 0.90
Unique properties of muscularis mucosae smooth muscle in guinea pig urinary bladder. Am J Physiol Regul Integr Comp Physiol (2011) 0.90
Calcium waves in intact guinea pig gallbladder smooth muscle cells. Am J Physiol Gastrointest Liver Physiol (2006) 0.89
Ca2+ sparks and K(Ca) channels: novel mechanisms to relax urinary bladder smooth muscle. Adv Exp Med Biol (2003) 0.89
A non-anesthetized mouse model for recording sensory urinary bladder activity. Front Neurol (2010) 0.88
Nerve-released acetylcholine contracts urinary bladder smooth muscle by inducing action potentials independently of IP3-mediated calcium release. Am J Physiol Regul Integr Comp Physiol (2010) 0.87
Vascular inward rectifier K+ channels as external K+ sensors in the control of cerebral blood flow. Microcirculation (2015) 0.86
Hypercontractility and impaired sildenafil relaxations in the BKCa channel deletion model of erectile dysfunction. Am J Physiol Regul Integr Comp Physiol (2008) 0.86
Neurovascular signaling in the brain and the pathological consequences of hypertension. Am J Physiol Heart Circ Physiol (2013) 0.86
Calcium and diabetic vascular dysfunction. Focus on "Elevated Ca(2+) sparklet activity during acute hyperglycemia and diabetes in cerebral arterial smooth muscle cells". Am J Physiol Cell Physiol (2009) 0.86
Identification of a spontaneously active, Na+-permeable channel in guinea pig gallbladder smooth muscle. Am J Physiol Gastrointest Liver Physiol (2005) 0.86
Activity-dependent NFATc3 nuclear accumulation in pericytes from cortical parenchymal microvessels. Am J Physiol Cell Physiol (2007) 0.86
Subarachnoid blood converts neurally evoked vasodilation to vasoconstriction in rat brain cortex. Acta Neurochir Suppl (2013) 0.85
Ryanodine receptors, calcium signaling, and regulation of vascular tone in the cerebral parenchymal microcirculation. Microcirculation (2013) 0.84
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Prostaglandin E2, a postulated astrocyte-derived neurovascular coupling agent, constricts rather than dilates parenchymal arterioles. J Cereb Blood Flow Metab (2013) 0.84
Ca(2+) sparks and BK currents in gallbladder myocytes: role in CCK-induced response. Am J Physiol Gastrointest Liver Physiol (2002) 0.82
ERG K+ channels modulate the electrical and contractile activities of gallbladder smooth muscle. Am J Physiol Gastrointest Liver Physiol (2002) 0.81
Perturbations of the cerebrovascular matrisome: A convergent mechanism in small vessel disease of the brain? J Cereb Blood Flow Metab (2016) 0.80
Local elementary purinergic-induced Ca2+ transients: from optical mapping of nerve activity to local Ca2+ signaling networks. J Gen Physiol (2010) 0.80
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Traumatic brain injury disrupts cerebrovascular tone through endothelial inducible nitric oxide synthase expression and nitric oxide gain of function. J Am Heart Assoc (2014) 0.78
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Sarcoplasmic reticulum and membrane currents. Novartis Found Symp (2002) 0.76
Opposing roles of smooth muscle BK channels and ryanodine receptors in the regulation of nerve-evoked constriction of mesenteric resistance arteries. Am J Physiol Heart Circ Physiol (2014) 0.76
Pinacidil induces vascular dilation and hyperemia in vivo and does not impact biophysical properties of neurons and astrocytes in vitro. Cleve Clin J Med (2009) 0.76
ATP induces guinea pig gallbladder smooth muscle excitability via the P2Y4 receptor and COX-1 activity. Am J Physiol Gastrointest Liver Physiol (2008) 0.75
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Channeling stress: inwardly-rectifying K+ channels in stress and disease. Channels (Austin) (2014) 0.75
A spoonful of sugar helps the KV channel activity go down. J Physiol (2006) 0.75
Amplified NO/cGMP-mediated relaxation and ryanodine receptor-to-BKCa channel signalling in corpus cavernosum smooth muscle from phospholamban knockout mice. Br J Pharmacol (2012) 0.75
Molecular coding of Kv1 channels to oppose myogenic constriction. Circ Res (2006) 0.75
Intraoperative Use of Vascular Ultrasound to Localize Thrombus in Left Ventricular Assist Device Exchange. Anesth Analg (2016) 0.75