Published in Science on May 04, 2012
Emerging role of the calcium-activated, small conductance, SK3 K+ channel in distal tubule function: regulation by TRPV4. PLoS One (2014) 1.46
Intravesical TRPV4 blockade reduces repeated variate stress-induced bladder dysfunction by increasing bladder capacity and decreasing voiding frequency in male rats. Am J Physiol Regul Integr Comp Physiol (2014) 1.40
The puzzle of TRPV4 channelopathies. EMBO Rep (2013) 1.33
The effects of hypertension on the cerebral circulation. Am J Physiol Heart Circ Physiol (2013) 1.25
Low intravascular pressure activates endothelial cell TRPV4 channels, local Ca2+ events, and IKCa channels, reducing arteriolar tone. Proc Natl Acad Sci U S A (2012) 1.24
Transient receptor potential channels in the vasculature. Physiol Rev (2015) 1.14
Brain endothelial TAK1 and NEMO safeguard the neurovascular unit. J Exp Med (2015) 1.10
Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle. J Gen Physiol (2014) 1.10
TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury. Am J Physiol Lung Cell Mol Physiol (2014) 1.07
Optical recording reveals novel properties of GSK1016790A-induced vanilloid transient receptor potential channel TRPV4 activity in primary human endothelial cells. Mol Pharmacol (2012) 1.06
Hydrogen sulfide dilates rat mesenteric arteries by activating endothelial large-conductance Ca²⁺-activated K⁺ channels and smooth muscle Ca²⁺ sparks. Am J Physiol Heart Circ Physiol (2013) 1.05
Recruitment of dynamic endothelial Ca2+ signals by the TRPA1 channel activator AITC in rat cerebral arteries. Microcirculation (2013) 1.02
TRPV4 and the regulation of vascular tone. J Cardiovasc Pharmacol (2013) 0.99
Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation. Sci Signal (2015) 0.97
TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension. Am J Physiol Cell Physiol (2013) 0.97
AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension. Sci Signal (2014) 0.97
Astrocyte regulation of cerebral vascular tone. Am J Physiol Heart Circ Physiol (2013) 0.95
Mechanisms of enhanced basal tone of brain parenchymal arterioles during early postischemic reperfusion: role of ET-1-induced peroxynitrite generation. J Cereb Blood Flow Metab (2013) 0.95
Selective activation of KCa3.1 and CRAC channels by P2Y2 receptors promotes Ca(2+) signaling, store refilling and migration of rat microglial cells. PLoS One (2013) 0.94
Primary cilia signaling mediates intraocular pressure sensation. Proc Natl Acad Sci U S A (2014) 0.91
Positive feedback regulation of agonist-stimulated endothelial Ca2+ dynamics by KCa3.1 channels in mouse mesenteric arteries. Arterioscler Thromb Vasc Biol (2013) 0.91
Regulation of cellular communication by signaling microdomains in the blood vessel wall. Pharmacol Rev (2014) 0.90
Vascular TRP channels: performing under pressure and going with the flow. Physiology (Bethesda) (2014) 0.89
Human skeletal dysplasia caused by a constitutive activated transient receptor potential vanilloid 4 (TRPV4) cation channel mutation. Exp Mol Med (2012) 0.89
Role of TRP channels in the cardiovascular system. Am J Physiol Heart Circ Physiol (2014) 0.88
Perivascular innervation: a multiplicity of roles in vasomotor control and myoendothelial signaling. Microcirculation (2013) 0.87
Calcium-activated potassium channels in ischemia reperfusion: a brief update. Front Physiol (2014) 0.87
Endothelial TRPV4 channels mediate dilation of cerebral arteries: impairment and recovery in cerebrovascular pathologies related to Alzheimer's disease. Br J Pharmacol (2013) 0.87
TRP channel Ca(2+) sparklets: fundamental signals underlying endothelium-dependent hyperpolarization. Am J Physiol Cell Physiol (2013) 0.86
Activity and Ca²⁺ regulate the mobility of TRPV1 channels in the plasma membrane of sensory neurons. Elife (2015) 0.86
Arachidonic acid-induced dilation in human coronary arterioles: convergence of signaling mechanisms on endothelial TRPV4-mediated Ca2+ entry. J Am Heart Assoc (2013) 0.86
Coordination of intercellular Ca(2+) signaling in endothelial cell tubes of mouse resistance arteries. Microcirculation (2012) 0.86
Local regulation of L-type Ca²⁺ channel sparklets in arterial smooth muscle. Microcirculation (2013) 0.85
Hyperglycemia and Diabetes Downregulate the Functional Expression of TRPV4 Channels in Retinal Microvascular Endothelium. PLoS One (2015) 0.84
Activation of endothelial transient receptor potential C3 channel is required for small conductance calcium-activated potassium channel activation and sustained endothelial hyperpolarization and vasodilation of cerebral artery. J Am Heart Assoc (2014) 0.83
Stochastic model of endothelial TRPV4 calcium sparklets: effect of bursting and cooperativity on EDH. Biophys J (2015) 0.83
GPCR-mediated EGF receptor transactivation regulates TRPV4 action in the vasculature. Br J Pharmacol (2015) 0.82
Ageing alters perivascular nerve function of mouse mesenteric arteries in vivo. J Physiol (2012) 0.82
Endothelial dysfunction in experimental models of arterial hypertension: cause or consequence? Biomed Res Int (2014) 0.82
Dynamic visualization of calcium-dependent signaling in cellular microdomains. Cell Calcium (2015) 0.82
Modulation of T-type calcium channels by bioactive lipids. Pflugers Arch (2014) 0.81
The role of cGMP/cGKI signalling and Trpc channels in regulation of vascular tone. Cardiovasc Res (2013) 0.81
Characterization of blood pressure and endothelial function in TRPV4-deficient mice with l-NAME- and angiotensin II-induced hypertension. Physiol Rep (2014) 0.81
Less is more: minimal expression of myoendothelial gap junctions optimizes cell-cell communication in virtual arterioles. J Physiol (2014) 0.81
Hemoglobin α/eNOS coupling at myoendothelial junctions is required for nitric oxide scavenging during vasoconstriction. Arterioscler Thromb Vasc Biol (2014) 0.81
The myoendothelial junction: connections that deliver the message. Physiology (Bethesda) (2014) 0.81
The role of epoxyeicosatrienoic acids in the cardiovascular system. Br J Clin Pharmacol (2015) 0.81
TACTIC: Trans-Agency Consortium for Trauma-Induced Coagulopathy. J Thromb Haemost (2015) 0.81
Upregulation of SK3 and IK1 channels contributes to the enhanced endothelial calcium signaling and the preserved coronary relaxation in obese Zucker rats. PLoS One (2014) 0.81
Membrane potential governs calcium influx into microvascular endothelium: integral role for muscarinic receptor activation. J Physiol (2015) 0.81
Functional Tuning of Intrinsic Endothelial Ca2+ Dynamics in Swine Coronary Arteries. Circ Res (2016) 0.81
Pressure-dependent regulation of Ca(2+) signalling in the vascular endothelium. J Physiol (2015) 0.81
Plasma from patients with HELLP syndrome increases blood-brain barrier permeability. Reprod Sci (2014) 0.80
Analysis of responses to the TRPV4 agonist GSK1016790A in the pulmonary vascular bed of the intact-chest rat. Am J Physiol Heart Circ Physiol (2013) 0.80
Inward rectifier potassium (Kir2.1) channels as end-stage boosters of endothelium-dependent vasodilators. J Physiol (2016) 0.80
Preconditioning with soluble guanylate cyclase activation prevents postischemic inflammation and reduces nitrate tolerance in heme oxygenase-1 knockout mice. Am J Physiol Heart Circ Physiol (2013) 0.80
Vasodilator responses to acetylcholine are not mediated by the activation of soluble guanylate cyclase or TRPV4 channels in the rat. Am J Physiol Heart Circ Physiol (2014) 0.80
Deciphering physiological role of the mechanosensitive TRPV4 channel in the distal nephron. Am J Physiol Renal Physiol (2014) 0.80
Partial opening and subconductance gating of mechanosensitive ion channels in dystrophic skeletal muscle. J Physiol (2012) 0.80
Hydrogen sulfide-induced vasodilation mediated by endothelial TRPV4 channels. Am J Physiol Heart Circ Physiol (2016) 0.80
Molecular and functional characterization of Kv 7 channels in penile arteries and corpus cavernosum of healthy and metabolic syndrome rats. Br J Pharmacol (2016) 0.79
Decoding dynamic Ca(2+) signaling in the vascular endothelium. Front Physiol (2014) 0.79
Clusters of specialized detector cells provide sensitive and high fidelity receptor signaling in the intact endothelium. FASEB J (2016) 0.79
Calcineurin/nuclear factor of activated T cells-coupled vanilliod transient receptor potential channel 4 ca2+ sparklets stimulate airway smooth muscle cell proliferation. Am J Respir Cell Mol Biol (2014) 0.79
Role of impaired endothelial cell Ca(2+) signaling in uteroplacental vascular dysfunction during diabetic rat pregnancy. Am J Physiol Heart Circ Physiol (2013) 0.79
Functional TRPV and TRPM channels in human preadipocytes. Pflugers Arch (2013) 0.79
Functional coupling of TRPV4, IK, and SK channels contributes to Ca(2+)-dependent endothelial injury in rodent lung. Pulm Circ (2015) 0.79
TRPV4 and K(Ca) ion channels functionally couple as osmosensors in the paraventricular nucleus. Br J Pharmacol (2015) 0.79
Acetylcholine released by endothelial cells facilitates flow-mediated dilatation. J Physiol (2016) 0.78
Calcium dynamics in vascular smooth muscle. Microcirculation (2013) 0.78
Pressure-induced oxidative activation of PKG enables vasoregulation by Ca2+ sparks and BK channels. Sci Signal (2016) 0.78
Advanced age decreases local calcium signaling in endothelium of mouse mesenteric arteries in vivo. Am J Physiol Heart Circ Physiol (2016) 0.78
Unitary TRPV3 channel Ca2+ influx events elicit endothelium-dependent dilation of cerebral parenchymal arterioles. Am J Physiol Heart Circ Physiol (2015) 0.78
Ovariectomy-induced reductions in endothelial SK3 channel activity and endothelium-dependent vasorelaxation in murine mesenteric arteries. PLoS One (2014) 0.78
Traumatic brain injury disrupts cerebrovascular tone through endothelial inducible nitric oxide synthase expression and nitric oxide gain of function. J Am Heart Assoc (2014) 0.78
Translocation of PKG1α acts on TRPV4-C1 heteromeric channels to inhibit endothelial Ca(2+) entry. Acta Pharmacol Sin (2016) 0.78
CaV1.2 sparklets in heart and vascular smooth muscle. J Mol Cell Cardiol (2012) 0.78
Integration and Modulation of Intercellular Signaling Underlying Blood Flow Control. J Vasc Res (2015) 0.78
Depressed perivascular sensory innervation of mouse mesenteric arteries with advanced age. J Physiol (2015) 0.78
Traumatic Brain Injury Causes Endothelial Dysfunction in the Systemic Microcirculation through Arginase-1-Dependent Uncoupling of Endothelial Nitric Oxide Synthase. J Neurotrauma (2016) 0.78
Endothelium-Derived Hyperpolarization and Coronary Vasodilation: Diverse and Integrated Roles of Epoxyeicosatrienoic Acids, Hydrogen Peroxide, and Gap Junctions. Microcirculation (2016) 0.78
Genetic deficit of KCa 3.1 channels protects against pulmonary circulatory collapse induced by TRPV4 channel activation. Br J Pharmacol (2015) 0.78
Aging-related alterations in eNOS and nNOS responsiveness and smooth muscle reactivity of murine basilar arteries are modulated by apocynin and phosphorylation of myosin phosphatase targeting subunit-1. J Cereb Blood Flow Metab (2016) 0.77
Blockade or deletion of transient receptor potential vanilloid 4 (TRPV4) is not protective in a murine model of sepsis. F1000Res (2015) 0.77
Ion channel networks in the control of cerebral blood flow. J Cereb Blood Flow Metab (2015) 0.77
A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis. Oncotarget (2016) 0.77
Targeting the Small- and Intermediate-Conductance Ca-Activated Potassium Channels: The Drug-Binding Pocket at the Channel/Calmodulin Interface. Neurosignals (2014) 0.77
Angiotensin II induces membrane trafficking of natively expressed transient receptor potential vanilloid type 4 channels in hypothalamic 4B cells. Am J Physiol Regul Integr Comp Physiol (2014) 0.77
Advancing Age Decreases Pressure-Sensitive Modulation of Calcium Signaling in the Endothelium of Intact and Pressurized Arteries. J Vasc Res (2017) 0.76
Small caliber arterial endothelial cells calcium signals elicited by PAR2 are preserved from endothelial dysfunction. Pharmacol Res Perspect (2015) 0.76
Opposing roles of smooth muscle BK channels and ryanodine receptors in the regulation of nerve-evoked constriction of mesenteric resistance arteries. Am J Physiol Heart Circ Physiol (2014) 0.76
Pharmacological inhibitors of TRPV4 channels reduce cytokine production, restore endothelial function and increase survival in septic mice. Sci Rep (2016) 0.76
Neurovascular and Cognitive failure in Alzheimer's Disease: Benefits of Cardiovascular Therapy. Cell Mol Neurobiol (2016) 0.76
Store-operated interactions between plasmalemmal STIM1 and TRPC1 proteins stimulate PLCβ1 to induce TRPC1 channel activation in vascular smooth muscle cells. J Physiol (2016) 0.76
Cell biology. Superresolution subspace signaling. Science (2012) 0.76
Eugenol dilates mesenteric arteries and reduces systemic BP by activating endothelial cell TRPV4 channels. Br J Pharmacol (2015) 0.76
Expression of phosphoinositide-specific phospholipase C isoforms in native endothelial cells. PLoS One (2015) 0.76
L-type Ca2+ channel sparklets revealed by TIRF microscopy in mouse urinary bladder smooth muscle. PLoS One (2014) 0.76
TRPV4: physiological role and therapeutic potential in respiratory diseases. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.76
Ca2+ signalling between single L-type Ca2+ channels and ryanodine receptors in heart cells. Nature (2001) 3.79
Calcium-activated potassium channels and the regulation of vascular tone. Physiology (Bethesda) (2006) 3.25
Functional architecture of inositol 1,4,5-trisphosphate signaling in restricted spaces of myoendothelial projections. Proc Natl Acad Sci U S A (2008) 2.47
Endothelium-derived hyperpolarising factors and associated pathways: a synopsis. Pflugers Arch (2010) 2.29
Propagated endothelial Ca2+ waves and arteriolar dilation in vivo: measurements in Cx40BAC GCaMP2 transgenic mice. Circ Res (2007) 2.13
The vanilloid transient receptor potential channel TRPV4: from structure to disease. Prog Biophys Mol Biol (2009) 2.13
Systemic activation of the transient receptor potential vanilloid subtype 4 channel causes endothelial failure and circulatory collapse: Part 2. J Pharmacol Exp Ther (2008) 1.98
Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis. Proc Natl Acad Sci U S A (2010) 1.96
Arterial response to shear stress critically depends on endothelial TRPV4 expression. PLoS One (2007) 1.79
Role of caveolar compartmentation in endothelium-derived hyperpolarizing factor-mediated relaxation: Ca2+ signals and gap junction function are regulated by caveolin in endothelial cells. Circulation (2008) 1.79
TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress. Am J Physiol Heart Circ Physiol (2009) 1.76
Transient receptor potential vanilloid type 4-deficient mice exhibit impaired endothelium-dependent relaxation induced by acetylcholine in vitro and in vivo. Hypertension (2009) 1.51
Myoendothelial gap junctions may provide the pathway for EDHF in mouse mesenteric artery. J Vasc Res (2003) 1.49
TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure. Am J Physiol Heart Circ Physiol (2009) 1.47
NO: the primary EDRF. J Mol Cell Cardiol (1999) 1.46
Recording single-channel activity of inositol trisphosphate receptors in intact cells with a microscope, not a patch clamp. J Gen Physiol (2010) 1.24
Endothelial potassium channels, endothelium-dependent hyperpolarization and the regulation of vascular tone in health and disease. Clin Exp Pharmacol Physiol (2004) 1.22
Arachidonic acid cascade in endothelial pathobiology. Microvasc Res (2005) 1.07
Interdomain interactions control Ca2+-dependent potentiation in the cation channel TRPV4. PLoS One (2010) 0.98
Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. Science (2002) 5.89
Control of stem cell fate by physical interactions with the extracellular matrix. Cell Stem Cell (2009) 5.43
Imaging cellular signals in the heart in vivo: Cardiac expression of the high-signal Ca2+ indicator GCaMP2. Proc Natl Acad Sci U S A (2006) 4.71
Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts. Nature (2012) 3.63
Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia. Nature (2007) 3.46
Local potassium signaling couples neuronal activity to vasodilation in the brain. Nat Neurosci (2006) 3.27
Calcium-activated potassium channels and the regulation of vascular tone. Physiology (Bethesda) (2006) 3.25
TRPV4 forms a novel Ca2+ signaling complex with ryanodine receptors and BKCa channels. Circ Res (2005) 3.22
Overactive bladder and incontinence in the absence of the BK large conductance Ca2+-activated K+ channel. J Biol Chem (2004) 2.96
Transient receptor potential channels regulate myogenic tone of resistance arteries. Circ Res (2002) 2.59
Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy. Nature (2002) 2.59
Structural basis for calcium sensing by GCaMP2. Structure (2008) 2.52
Transient receptor potential vanilloid 4-mediated disruption of the alveolar septal barrier: a novel mechanism of acute lung injury. Circ Res (2006) 2.49
Functional architecture of inositol 1,4,5-trisphosphate signaling in restricted spaces of myoendothelial projections. Proc Natl Acad Sci U S A (2008) 2.47
c-kit+ precursors support postinfarction myogenesis in the neonatal, but not adult, heart. Proc Natl Acad Sci U S A (2012) 2.35
Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice. J Physiol (2006) 2.34
Altered expression of small-conductance Ca2+-activated K+ (SK3) channels modulates arterial tone and blood pressure. Circ Res (2003) 2.25
Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding. J Clin Invest (2007) 2.19
Calcium dynamics in cortical astrocytes and arterioles during neurovascular coupling. Circ Res (2004) 2.17
Propagated endothelial Ca2+ waves and arteriolar dilation in vivo: measurements in Cx40BAC GCaMP2 transgenic mice. Circ Res (2007) 2.13
c-kit expression identifies cardiovascular precursors in the neonatal heart. Proc Natl Acad Sci U S A (2009) 2.06
TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis. Cell (2012) 2.03
Functional characterization of TRPV4 as an osmotically sensitive ion channel in porcine articular chondrocytes. Arthritis Rheum (2009) 2.02
Astrocytic endfoot Ca2+ and BK channels determine both arteriolar dilation and constriction. Proc Natl Acad Sci U S A (2010) 1.90
Transient receptor potential canonical-3 channel-dependent fibroblast regulation in atrial fibrillation. Circulation (2012) 1.81
Modulation of the molecular composition of large conductance, Ca(2+) activated K(+) channels in vascular smooth muscle during hypertension. J Clin Invest (2003) 1.79
Arterial response to shear stress critically depends on endothelial TRPV4 expression. PLoS One (2007) 1.79
BAC transgenic mice express enhanced green fluorescent protein in central and peripheral cholinergic neurons. Physiol Genomics (2006) 1.76
Chondroprotective role of the osmotically sensitive ion channel transient receptor potential vanilloid 4: age- and sex-dependent progression of osteoarthritis in Trpv4-deficient mice. Arthritis Rheum (2010) 1.75
A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery. J Biol Chem (2006) 1.70
TRPV4 mediates pain-related behavior induced by mild hypertonic stimuli in the presence of inflammatory mediator. Pain (2005) 1.69
Differential regulation of SK and BK channels by Ca(2+) signals from Ca(2+) channels and ryanodine receptors in guinea-pig urinary bladder myocytes. J Physiol (2002) 1.65
Selective role for TRPV4 ion channels in visceral sensory pathways. Gastroenterology (2008) 1.63
Regulation of calcium-activated chloride channels in smooth muscle cells: a complex picture is emerging. Can J Physiol Pharmacol (2005) 1.62
Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice. J Clin Invest (2005) 1.61
Smooth muscle Notch1 mediates neointimal formation after vascular injury. Circulation (2009) 1.58
Signaling between SR and plasmalemma in smooth muscle: sparks and the activation of Ca2+-sensitive ion channels. Cell Calcium (2003) 1.56
Functional coupling of calcineurin and protein kinase A in mouse ventricular myocytes. J Physiol (2002) 1.54
Differential regulation of Ca2+-activated K+ channels by beta-adrenoceptors in guinea pig urinary bladder smooth muscle. Am J Physiol Cell Physiol (2005) 1.54
High blood pressure arising from a defect in vascular function. Proc Natl Acad Sci U S A (2008) 1.50
Differential patterning of cGMP in vascular smooth muscle cells revealed by single GFP-linked biosensors. Proc Natl Acad Sci U S A (2007) 1.50
Urinary bladder instability induced by selective suppression of the murine small conductance calcium-activated potassium (SK3) channel. J Physiol (2003) 1.48
TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure. Am J Physiol Heart Circ Physiol (2009) 1.47
Ca2+-activated K+ channels in murine endothelial cells: block by intracellular calcium and magnesium. J Gen Physiol (2008) 1.46
Beta-adrenergic relaxation of mouse urinary bladder smooth muscle in the absence of large-conductance Ca2+-activated K+ channel. Am J Physiol Renal Physiol (2008) 1.45
Endothelial SK(Ca) and IK(Ca) channels regulate brain parenchymal arteriolar diameter and cortical cerebral blood flow. J Cereb Blood Flow Metab (2010) 1.44
Erectile dysfunction in mice lacking the large-conductance calcium-activated potassium (BK) channel. J Physiol (2005) 1.43
Ion channels in smooth muscle: regulators of intracellular calcium and contractility. Can J Physiol Pharmacol (2005) 1.41
Ca2+-sensing transgenic mice: postsynaptic signaling in smooth muscle. J Biol Chem (2004) 1.39
TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells. Proc Natl Acad Sci U S A (2008) 1.36
Elementary purinergic Ca2+ transients evoked by nerve stimulation in rat urinary bladder smooth muscle. J Physiol (2005) 1.36
TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs. Am J Physiol Lung Cell Mol Physiol (2007) 1.33
Negative feedback regulation of nerve-mediated contractions by KCa channels in mouse urinary bladder smooth muscle. Am J Physiol Regul Integr Comp Physiol (2005) 1.32
The pump, the exchanger, and endogenous ouabain: signaling mechanisms that link salt retention to hypertension. Hypertension (2008) 1.32
Transient receptor potential vanilloid-4 has a major role in visceral hypersensitivity symptoms. Gastroenterology (2008) 1.31
Fundamental increase in pressure-dependent constriction of brain parenchymal arterioles from subarachnoid hemorrhage model rats due to membrane depolarization. Am J Physiol Heart Circ Physiol (2010) 1.31
TRPV4-mediated calcium influx into human bronchial epithelia upon exposure to diesel exhaust particles. Environ Health Perspect (2011) 1.29
Hydrophobic bile salts inhibit gallbladder smooth muscle function via stimulation of GPBAR1 receptors and activation of KATP channels. J Physiol (2010) 1.29
Transient receptor potential (TRP) channels, vascular tone and autoregulation of cerebral blood flow. Clin Exp Pharmacol Physiol (2008) 1.29
Transient receptor potential vanilloid 4: The sixth sense of the musculoskeletal system? Ann N Y Acad Sci (2010) 1.26
The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells. J Neurosci (2011) 1.26
Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia. Am J Physiol Gastrointest Liver Physiol (2008) 1.25
Type-3 ryanodine receptors mediate hypoxia-, but not neurotransmitter-induced calcium release and contraction in pulmonary artery smooth muscle cells. J Gen Physiol (2005) 1.25
RYR2 proteins contribute to the formation of Ca(2+) sparks in smooth muscle. J Gen Physiol (2004) 1.25
High vascular pressure-induced lung injury requires P450 epoxygenase-dependent activation of TRPV4. Am J Respir Cell Mol Biol (2007) 1.24
Stretch-induced calcium release in smooth muscle. J Gen Physiol (2002) 1.23
Frequency encoding of cholinergic- and purinergic-mediated signaling to mouse urinary bladder smooth muscle: modulation by BK channels. Am J Physiol Regul Integr Comp Physiol (2006) 1.22
Nuclear factor of activated T cells and serum response factor cooperatively regulate the activity of an alpha-actin intronic enhancer. J Biol Chem (2005) 1.21
Morphological and physiological evidence for interstitial cell of Cajal-like cells in the guinea pig gallbladder. J Physiol (2007) 1.20
TRPV4 channels stimulate Ca2+-induced Ca2+ release in astrocytic endfeet and amplify neurovascular coupling responses. Proc Natl Acad Sci U S A (2013) 1.20
Acidosis dilates brain parenchymal arterioles by conversion of calcium waves to sparks to activate BK channels. Circ Res (2011) 1.19
Properties and molecular basis of the mouse urinary bladder voltage-gated K+ current. J Physiol (2003) 1.19
Calcium signaling in smooth muscle. Cold Spring Harb Perspect Biol (2011) 1.19
Local subplasma membrane Ca2+ signals detected by a tethered Ca2+ sensor. Proc Natl Acad Sci U S A (2006) 1.18
Shiga toxin 2 affects the central nervous system through receptor globotriaosylceramide localized to neurons. J Infect Dis (2008) 1.16
Automated region of interest analysis of dynamic Ca²+ signals in image sequences. Am J Physiol Cell Physiol (2012) 1.16
Dynamic inositol trisphosphate-mediated calcium signals within astrocytic endfeet underlie vasodilation of cerebral arterioles. J Gen Physiol (2006) 1.16
TRPV4 channels augment macrophage activation and ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol (2010) 1.15
Membrane stretch-induced activation of a TRPM4-like nonselective cation channel in cerebral artery myocytes. J Pharmacol Sci (2007) 1.15
FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells. Am J Physiol Cell Physiol (2003) 1.14
Intraluminal pressure is a stimulus for NFATc3 nuclear accumulation: role of calcium, endothelium-derived nitric oxide, and cGMP-dependent protein kinase. J Biol Chem (2003) 1.14