Published in FEBS J on May 01, 2005
Cas6 is an endoribonuclease that generates guide RNAs for invader defense in prokaryotes. Genes Dev (2008) 7.09
RNA-binding proteins and post-transcriptional gene regulation. FEBS Lett (2008) 5.00
Molecular basis of RNA recognition by the human alternative splicing factor Fox-1. EMBO J (2005) 3.91
Interaction of the Cas6 riboendonuclease with CRISPR RNAs: recognition and cleavage. Structure (2011) 3.58
Unravelling the structural and mechanistic basis of CRISPR-Cas systems. Nat Rev Microbiol (2014) 3.48
Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going? Microbiol Mol Biol Rev (2006) 3.31
Muscleblind-like 1 interacts with RNA hairpins in splicing target and pathogenic RNAs. Nucleic Acids Res (2007) 2.95
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Structural and functional characterization of an archaeal clustered regularly interspaced short palindromic repeat (CRISPR)-associated complex for antiviral defense (CASCADE). J Biol Chem (2011) 2.86
Structural insights into TDP-43 in nucleic-acid binding and domain interactions. Nucleic Acids Res (2009) 2.37
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Determinants of exon 7 splicing in the spinal muscular atrophy genes, SMN1 and SMN2. Am J Hum Genet (2005) 2.29
Crystal structure of hypothetical protein TTHB192 from Thermus thermophilus HB8 reveals a new protein family with an RNA recognition motif-like domain. Protein Sci (2006) 2.29
Memory T cell RNA rearrangement programmed by heterogeneous nuclear ribonucleoprotein hnRNPLL. Immunity (2008) 2.13
TDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicing. J Biol Chem (2008) 1.98
Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65. Mol Cell (2006) 1.83
Molecular basis of RNA recognition and TAP binding by the SR proteins SRp20 and 9G8. EMBO J (2006) 1.78
Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions. Structure (2009) 1.77
Interaction of yeast RNA-binding proteins Nrd1 and Nab3 with RNA polymerase II terminator elements. RNA (2007) 1.72
7SK snRNP/P-TEFb couples transcription elongation with alternative splicing and is essential for vertebrate development. Proc Natl Acad Sci U S A (2009) 1.71
Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL. Blood (2008) 1.69
A second, non-canonical RNA-dependent RNA polymerase in SARS coronavirus. EMBO J (2006) 1.69
Structural insights into RNA recognition by the alternate-splicing regulator CUG-binding protein 1. Structure (2010) 1.67
Fox-1 family of RNA-binding proteins. Cell Mol Life Sci (2009) 1.67
Conserved RNA secondary structures promote alternative splicing. RNA (2008) 1.63
Conserved and divergent features of the structure and function of La and La-related proteins (LARPs). Biochim Biophys Acta (2010) 1.58
Functional dissection of the human TNRC6 (GW182-related) family of proteins. Mol Cell Biol (2009) 1.49
CRISPR interference: a structural perspective. Biochem J (2013) 1.48
Structure of the heterodimer of human NONO and paraspeckle protein component 1 and analysis of its role in subnuclear body formation. Proc Natl Acad Sci U S A (2012) 1.46
The YTH domain is a novel RNA binding domain. J Biol Chem (2010) 1.45
A comprehensive analysis of the La-motif protein superfamily. RNA (2009) 1.44
Recognition of polyadenosine RNA by zinc finger proteins. Proc Natl Acad Sci U S A (2007) 1.43
Reciprocal regulation of glycine-rich RNA-binding proteins via an interlocked feedback loop coupling alternative splicing to nonsense-mediated decay in Arabidopsis. Nucleic Acids Res (2008) 1.43
A Novel Candidate Gene for Temperature-Dependent Sex Determination in the Common Snapping Turtle. Genetics (2016) 1.42
The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing. Nucleic Acids Res (2009) 1.42
Novel splicing factor RBM25 modulates Bcl-x pre-mRNA 5' splice site selection. Mol Cell Biol (2008) 1.41
The rice pentatricopeptide repeat protein RF5 restores fertility in Hong-Lian cytoplasmic male-sterile lines via a complex with the glycine-rich protein GRP162. Plant Cell (2012) 1.41
Non-LTR retrotransposons encode noncanonical RRM domains in their first open reading frame. Proc Natl Acad Sci U S A (2009) 1.40
Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development. J Cell Biol (2006) 1.37
Cooperative-binding and splicing-repressive properties of hnRNP A1. Mol Cell Biol (2009) 1.37
NMR structure of the three quasi RNA recognition motifs (qRRMs) of human hnRNP F and interaction studies with Bcl-x G-tract RNA: a novel mode of RNA recognition. Nucleic Acids Res (2006) 1.34
Deep mutational scanning of an RRM domain of the Saccharomyces cerevisiae poly(A)-binding protein. RNA (2013) 1.34
Structure-based prediction of RNA-binding domains and RNA-binding sites and application to structural genomics targets. Nucleic Acids Res (2010) 1.33
The transcription-dependent dissociation of P-TEFb-HEXIM1-7SK RNA relies upon formation of hnRNP-7SK RNA complexes. Mol Cell Biol (2007) 1.32
Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition. EMBO J (2007) 1.32
The RNA-binding protein TbDRBD3 regulates the stability of a specific subset of mRNAs in trypanosomes. Nucleic Acids Res (2008) 1.32
Defining the molecular profile of planarian pluripotent stem cells using a combinatorial RNAseq, RNA interference and irradiation approach. Genome Biol (2012) 1.31
RNA looping by PTB: Evidence using FRET and NMR spectroscopy for a role in splicing repression. Proc Natl Acad Sci U S A (2010) 1.29
Classifying RNA-binding proteins based on electrostatic properties. PLoS Comput Biol (2008) 1.29
Structural and functional analysis of RNA and TAP binding to SF2/ASF. EMBO Rep (2007) 1.28
RNA Controls PolyQ Protein Phase Transitions. Mol Cell (2015) 1.28
RNA recognition by double-stranded RNA binding domains: a matter of shape and sequence. Cell Mol Life Sci (2012) 1.28
Involvement of p54(nrb), a PSF partner protein, in DNA double-strand break repair and radioresistance. Nucleic Acids Res (2009) 1.27
Grabbing the message: structural basis of mRNA 3'UTR recognition by Hrp1. EMBO J (2006) 1.26
The testis-specific human protein RBMY recognizes RNA through a novel mode of interaction. EMBO Rep (2007) 1.25
A multispecies comparison of the metazoan 3'-processing downstream elements and the CstF-64 RNA recognition motif. BMC Genomics (2006) 1.25
The RNA recognition motif of eukaryotic translation initiation factor 3g (eIF3g) is required for resumption of scanning of posttermination ribosomes for reinitiation on GCN4 and together with eIF3i stimulates linear scanning. Mol Cell Biol (2010) 1.21
The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina. J Comp Neurol (2014) 1.21
Review: transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration. Neuropathol Appl Neurobiol (2010) 1.19
Multiple roles for polypyrimidine tract binding (PTB) proteins in trypanosome RNA metabolism. RNA (2009) 1.19
The CRISPR-associated gene cas2 of Legionella pneumophila is required for intracellular infection of amoebae. MBio (2013) 1.18
Structure of the two most C-terminal RNA recognition motifs of PTB using segmental isotope labeling. EMBO J (2005) 1.18
RNA binding protein with multiple splicing: a new marker for retinal ganglion cells. Invest Ophthalmol Vis Sci (2009) 1.17
Discovery of a novel type of autophagy targeting RNA. Autophagy (2013) 1.17
Structure and interactions of the first three RNA recognition motifs of splicing factor prp24. J Mol Biol (2007) 1.14
Structural analysis reveals conformational plasticity in the recognition of RNA 3' ends by the human La protein. Structure (2008) 1.14
Rbfox3-regulated alternative splicing of Numb promotes neuronal differentiation during development. J Cell Biol (2013) 1.13
The role of positively charged amino acids and electrostatic interactions in the complex of U1A protein and U1 hairpin II RNA. Nucleic Acids Res (2006) 1.12
Functional insight into Maelstrom in the germline piRNA pathway: a unique domain homologous to the DnaQ-H 3'-5' exonuclease, its lineage-specific expansion/loss and evolutionarily active site switch. Biol Direct (2008) 1.11
Multiple U2AF65 binding sites within SF3b155: thermodynamic and spectroscopic characterization of protein-protein interactions among pre-mRNA splicing factors. J Mol Biol (2005) 1.10
The structure, function and evolution of proteins that bind DNA and RNA. Nat Rev Mol Cell Biol (2014) 1.10
Translational regulation of glutathione peroxidase 4 expression through guanine-rich sequence-binding factor 1 is essential for embryonic brain development. Genes Dev (2008) 1.09
Biochemical and NMR analyses of an SF3b155-p14-U2AF-RNA interaction network involved in branch point definition during pre-mRNA splicing. RNA (2006) 1.09
Spatial codes in dendritic BC1 RNA. J Cell Biol (2006) 1.08
Transcriptomic signatures of ash (Fraxinus spp.) phloem. PLoS One (2011) 1.07
Updating the CTD Story: From Tail to Epic. Genet Res Int (2011) 1.06
Engineering RNA-binding proteins for biology. FEBS J (2013) 1.06
Structure of Pfu Pop5, an archaeal RNase P protein. Proc Natl Acad Sci U S A (2006) 1.06
An RNA recognition motif-containing protein is required for plastid RNA editing in Arabidopsis and maize. Proc Natl Acad Sci U S A (2013) 1.05
The polypyrimidine tract binding protein is a monomer. RNA (2005) 1.05
Prediction of interacting single-stranded RNA bases by protein-binding patterns. J Mol Biol (2008) 1.04
Molecular determinants of the axonal mRNA transcriptome. Dev Neurobiol (2013) 1.04
Yra1 is required for S phase entry and affects Dia2 binding to replication origins. Mol Cell Biol (2007) 1.04
Nucleolin binds to a subset of selenoprotein mRNAs and regulates their expression. Nucleic Acids Res (2010) 1.03
Do collective atomic fluctuations account for cooperative effects? Molecular dynamics studies of the U1A-RNA complex. J Am Chem Soc (2006) 1.03
A study of collective atomic fluctuations and cooperativity in the U1A-RNA complex based on molecular dynamics simulations. J Struct Biol (2006) 1.03
Arginine methylation controls the subcellular localization and functions of the oncoprotein splicing factor SF2/ASF. Mol Cell Biol (2010) 1.03
Precursor-product discrimination by La protein during tRNA metabolism. Nat Struct Mol Biol (2009) 1.02
The role of RNA structure in the interaction of U1A protein with U1 hairpin II RNA. RNA (2006) 1.02
Drosophila SPF45: a bifunctional protein with roles in both splicing and DNA repair. PLoS Genet (2006) 1.01
Histone modifications and chromatin dynamics: a focus on filamentous fungi. FEMS Microbiol Rev (2008) 1.01
The impact of CRISPR repeat sequence on structures of a Cas6 protein-RNA complex. Protein Sci (2012) 1.00
New insights into functional roles of the polypyrimidine tract-binding protein. Int J Mol Sci (2013) 1.00
Structure function analysis of an ADP-ribosyltransferase type III effector and its RNA-binding target in plant immunity. J Biol Chem (2011) 0.99
RsiteDB: a database of protein binding pockets that interact with RNA nucleotide bases. Nucleic Acids Res (2008) 0.99
Defining NELF-E RNA binding in HIV-1 and promoter-proximal pause regions. PLoS Genet (2014) 0.99
A genetic screen for attenuated growth identifies genes crucial for intraerythrocytic development of Plasmodium falciparum. PLoS One (2010) 0.99
A novel occluded RNA recognition motif in Prp24 unwinds the U6 RNA internal stem loop. Nucleic Acids Res (2011) 0.99
Finding the target sites of RNA-binding proteins. Wiley Interdiscip Rev RNA (2013) 0.99
Structure of PTB bound to RNA: specific binding and implications for splicing regulation. Science (2005) 5.14
Molecular basis of RNA recognition by the human alternative splicing factor Fox-1. EMBO J (2005) 3.91
RNA recognition motifs: boring? Not quite. Curr Opin Struct Biol (2008) 3.78
Gac/Rsm signal transduction pathway of gamma-proteobacteria: from RNA recognition to regulation of social behaviour. Mol Microbiol (2007) 2.94
Sequence-specific binding of single-stranded RNA: is there a code for recognition? Nucleic Acids Res (2006) 2.89
Molecular basis for temperature sensing by an RNA thermometer. EMBO J (2006) 1.82
Molecular basis of RNA recognition and TAP binding by the SR proteins SRp20 and 9G8. EMBO J (2006) 1.78
The solution structure of the ADAR2 dsRBM-RNA complex reveals a sequence-specific readout of the minor groove. Cell (2010) 1.77
Shape-specific recognition in the structure of the Vts1p SAM domain with RNA. Nat Struct Mol Biol (2006) 1.61
A distinct structural region of the prokaryotic ubiquitin-like protein (Pup) is recognized by the N-terminal domain of the proteasomal ATPase Mpa. FEBS Lett (2009) 1.55
Molecular basis of messenger RNA recognition by the specific bacterial repressing clamp RsmA/CsrA. Nat Struct Mol Biol (2007) 1.48
RNA sequence- and shape-dependent recognition by proteins in the ribonucleoprotein particle. EMBO Rep (2005) 1.48
The YTH domain is a novel RNA binding domain. J Biol Chem (2010) 1.45
RRM-RNA recognition: NMR or crystallography…and new findings. Curr Opin Struct Biol (2012) 1.38
Prokaryotic ubiquitin-like protein (Pup) is coupled to substrates via the side chain of its C-terminal glutamate. J Am Chem Soc (2010) 1.36
NMR structure of the three quasi RNA recognition motifs (qRRMs) of human hnRNP F and interaction studies with Bcl-x G-tract RNA: a novel mode of RNA recognition. Nucleic Acids Res (2006) 1.34
Structure and specific RNA binding of ADAR2 double-stranded RNA binding motifs. Structure (2006) 1.31
Conformation of polypyrimidine tract binding protein in solution. Structure (2006) 1.30
RNA looping by PTB: Evidence using FRET and NMR spectroscopy for a role in splicing repression. Proc Natl Acad Sci U S A (2010) 1.29
RNA recognition by double-stranded RNA binding domains: a matter of shape and sequence. Cell Mol Life Sci (2012) 1.28
Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28. Nat Struct Mol Biol (2011) 1.26
The phosphoglucan phosphatase like sex Four2 dephosphorylates starch at the C3-position in Arabidopsis. Plant Cell (2011) 1.26
The testis-specific human protein RBMY recognizes RNA through a novel mode of interaction. EMBO Rep (2007) 1.25
Molecular basis of UG-rich RNA recognition by the human splicing factor TDP-43. Nat Struct Mol Biol (2013) 1.25
Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2-β1. Nat Struct Mol Biol (2011) 1.22
Structural basis of G-tract recognition and encaging by hnRNP F quasi-RRMs. Nat Struct Mol Biol (2010) 1.20
U1 snRNA directly interacts with polypyrimidine tract-binding protein during splicing repression. Mol Cell (2011) 1.18
A syn-anti conformational difference allows SRSF2 to recognize guanines and cytosines equally well. EMBO J (2011) 1.18
Structure of the two most C-terminal RNA recognition motifs of PTB using segmental isotope labeling. EMBO J (2005) 1.18
An altered-specificity ubiquitin-conjugating enzyme/ubiquitin-protein ligase pair. J Mol Biol (2004) 1.15
Solving the structure of PTB in complex with pyrimidine tracts: an NMR study of protein-RNA complexes of weak affinities. J Mol Biol (2006) 1.14
Structure determination and dynamics of protein-RNA complexes by NMR spectroscopy. Prog Nucl Magn Reson Spectrosc (2010) 1.11
In support of the BMRB. Nat Struct Mol Biol (2012) 1.09
ADAR proteins: double-stranded RNA and Z-DNA binding domains. Curr Top Microbiol Immunol (2012) 1.09
Plasticity of the β-trefoil protein fold in the recognition and control of invertebrate predators and parasites by a fungal defence system. PLoS Pathog (2012) 1.05
An extended dsRBD with a novel zinc-binding motif mediates nuclear retention of fission yeast Dicer. EMBO J (2011) 1.03
NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor. RNA (2005) 1.03
Solution structure of the ubiquitin-conjugating enzyme UbcH5B. J Mol Biol (2004) 1.00
Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition. Proc Natl Acad Sci U S A (2013) 0.98
Structural basis for sigma factor mimicry in the general stress response of Alphaproteobacteria. Proc Natl Acad Sci U S A (2012) 0.98
Solution structure of the two RNA recognition motifs of hnRNP A1 using segmental isotope labeling: how the relative orientation between RRMs influences the nucleic acid binding topology. J Biomol NMR (2012) 0.97
Recent advances in segmental isotope labeling of proteins: NMR applications to large proteins and glycoproteins. J Biomol NMR (2009) 0.95
A fast, efficient and sequence-independent method for flexible multiple segmental isotope labeling of RNA using ribozyme and RNase H cleavage. Nucleic Acids Res (2010) 0.94
Isotope labeling and segmental labeling of larger RNAs for NMR structural studies. Adv Exp Med Biol (2012) 0.94
A novel RNA pentaloop fold involved in targeting ADAR2. RNA (2005) 0.93
Structures of Pup ligase PafA and depupylase Dop from the prokaryotic ubiquitin-like modification pathway. Nat Commun (2012) 0.93
Structural and mechanistic insights into poly(uridine) tract recognition by the hnRNP C RNA recognition motif. J Am Chem Soc (2014) 0.92
Stabilization of branched oligosaccharides: Lewis(x) benefits from a nonconventional C-H···O hydrogen bond. J Am Chem Soc (2013) 0.92
NMR structure determination of a segmentally labeled glycoprotein using in vitro glycosylation. J Am Chem Soc (2009) 0.91
Solution structure and activation mechanism of ubiquitin-like small archaeal modifier proteins. J Mol Biol (2010) 0.91
A procedure to validate and correct the 13C chemical shift calibration of RNA datasets. J Biomol NMR (2012) 0.91
Molecular basis for the wide range of affinity found in Csr/Rsm protein-RNA recognition. Nucleic Acids Res (2014) 0.90
High-resolution structural analysis shows how Tah1 tethers Hsp90 to the R2TP complex. Structure (2013) 0.90
A strong 13C chemical shift signature provides the coordination mode of histidines in zinc-binding proteins. J Biomol NMR (2012) 0.89
Improved segmental isotope labeling methods for the NMR study of multidomain or large proteins: application to the RRMs of Npl3p and hnRNP L. J Mol Biol (2007) 0.89
Short, synthetic and selectively 13C-labeled RNA sequences for the NMR structure determination of protein-RNA complexes. Nucleic Acids Res (2006) 0.88
Dynamics and metal exchange properties of C4C4 RING domains from CNOT4 and the p44 subunit of TFIIH. J Mol Biol (2005) 0.87
Automated and assisted RNA resonance assignment using NMR chemical shift statistics. Nucleic Acids Res (2013) 0.87
Solution structure of the C-terminal domain of TFIIH P44 subunit reveals a novel type of C4C4 ring domain involved in protein-protein interactions. J Biol Chem (2005) 0.87
How a rotavirus hijacks the human protein synthesis machinery. Nat Struct Biol (2002) 0.87
Novel enzymatic activity derived from the Semliki Forest virus capsid protein. J Mol Biol (2007) 0.87
The high kinetic stability of a G-quadruplex limits hnRNP F qRRM3 binding to G-tract RNA. Nucleic Acids Res (2012) 0.85
Increase in backbone mobility of the VTS1p-SAM domain on binding to SRE-RNA. J Mol Biol (2009) 0.84
A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1. Proc Natl Acad Sci U S A (2014) 0.83
Changes in dynamics of SRE-RNA on binding to the VTS1p-SAM domain studied by 13C NMR relaxation. J Am Chem Soc (2008) 0.80
Resonance assignments of the two N-terminal RNA recognition motifs (RRM) of the human heterogeneous nuclear ribonucleoprotein F (HnRNP F). J Biomol NMR (2005) 0.77
Solution structure of the N-terminal dsRBD of Drosophila ADAR and interaction studies with RNA. Biochimie (2011) 0.77
NMR spectroscopy: an excellent tool to understand RNA and carbohydrate recognition by proteins. Chimia (Aarau) (2012) 0.76
Amino acid-selective segmental isotope labeling of multidomain proteins for structural biology. Chembiochem (2013) 0.76
Single-stranded nucleic acid recognition: is there a code after all? Structure (2013) 0.75