Published in Circ Res on April 28, 2005
ECM remodeling in hypertensive heart disease. J Clin Invest (2007) 4.03
Mechanical stress-strain sensors embedded in cardiac cytoskeleton: Z disk, titin, and associated structures. Am J Physiol Heart Circ Physiol (2006) 2.37
Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart. Genes Dev (2006) 2.29
Myocardial AKT: the omnipresent nexus. Physiol Rev (2011) 1.76
Cardiac Z-disc signaling network. J Biol Chem (2011) 1.25
Deletion of Ptpn11 (Shp2) in cardiomyocytes causes dilated cardiomyopathy via effects on the extracellular signal-regulated kinase/mitogen-activated protein kinase and RhoA signaling pathways. Circulation (2008) 1.20
A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein. Mol Cell Proteomics (2009) 1.11
Structural basis for assembly of Hsp90-Sgt1-CHORD protein complexes: implications for chaperoning of NLR innate immunity receptors. Mol Cell (2010) 1.07
IQGAP1 regulates ERK1/2 and AKT signalling in the heart and sustains functional remodelling upon pressure overload. Cardiovasc Res (2011) 1.04
Thrombospondin-4 is required for stretch-mediated contractility augmentation in cardiac muscle. Circ Res (2011) 1.02
Integrins and integrin-associated proteins in the cardiac myocyte. Circ Res (2014) 1.00
Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice. J Clin Invest (2013) 0.99
The sarcomeric Z-disc and Z-discopathies. J Biomed Biotechnol (2011) 0.99
Glycogen synthase kinase-3beta plays a pro-apoptotic role in beta-adrenergic receptor-stimulated apoptosis in adult rat ventricular myocytes: Role of beta1 integrins. J Mol Cell Cardiol (2006) 0.98
Integrins are the necessary links to hypertrophic growth in cardiomyocytes. J Signal Transduct (2011) 0.93
ERK1/2 activation in heart is controlled by melusin, focal adhesion kinase and the scaffold protein IQGAP1. J Cell Sci (2011) 0.83
Phosphoinositide 3-kinase (PI3K(p110alpha)) directly regulates key components of the Z-disc and cardiac structure. J Biol Chem (2011) 0.82
New insights into the molecular phenotype of eccentric hypertrophy. J Mol Cell Cardiol (2010) 0.79
Cardiac Gab1 deletion leads to dilated cardiomyopathy associated with mitochondrial damage and cardiomyocyte apoptosis. Cell Death Differ (2015) 0.77
Scaffold Proteins Regulating Extracellular Regulated Kinase Function in Cardiac Hypertrophy and Disease. Front Pharmacol (2016) 0.77
Melusin gene (ITGB1BP2) nucleotide variations study in hypertensive and cardiopathic patients. BMC Med Genet (2009) 0.77
Melusin Promotes a Protective Signal Transduction Cascade in Stressed Hearts. Front Mol Biosci (2016) 0.75
Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J Am Soc Nephrol (2009) 5.01
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways. Cell (2002) 4.35
PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects. Cell (2004) 3.87
Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche. Cancer Res (2011) 3.50
Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response. Nature (2002) 3.01
Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload. Nat Med (2002) 2.89
Emilin1 links TGF-beta maturation to blood pressure homeostasis. Cell (2006) 2.84
Positional control of cell fate through joint integrin/receptor protein kinase signaling. Annu Rev Cell Dev Biol (2003) 2.57
The persistent exclusion of older patients from ongoing clinical trials regarding heart failure. Arch Intern Med (2011) 2.55
Phosphoinositide 3-kinase gamma is an essential amplifier of mast cell function. Immunity (2002) 2.25
Microvesicles derived from mesenchymal stem cells enhance survival in a lethal model of acute kidney injury. PLoS One (2012) 2.23
Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development. Sci Signal (2008) 2.19
Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines. J Biol Chem (2001) 2.06
p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis. Cancer Res (2006) 1.92
Microvesicles derived from human bone marrow mesenchymal stem cells inhibit tumor growth. Stem Cells Dev (2012) 1.91
Myocardial Pitx2 differentially regulates the left atrial identity and ventricular asymmetric remodeling programs. Circ Res (2008) 1.83
Prediction of human disease genes by human-mouse conserved coexpression analysis. PLoS Comput Biol (2008) 1.81
Hemopexin: structure, function, and regulation. DNA Cell Biol (2002) 1.75
Leptin effect on endothelial nitric oxide is mediated through Akt-endothelial nitric oxide synthase phosphorylation pathway. Diabetes (2002) 1.65
Pressure-induced vascular oxidative stress is mediated through activation of integrin-linked kinase 1/betaPIX/Rac-1 pathway. Hypertension (2009) 1.61
MIDAW: a web tool for statistical analysis of microarray data. Nucleic Acids Res (2005) 1.60
Cooperation between insulin and leptin in the modulation of vascular tone. Hypertension (2003) 1.60
Extracellular signal-regulated kinases 1 and 2 regulate the balance between eccentric and concentric cardiac growth. Circ Res (2010) 1.56
Increased basal nitric oxide release despite enhanced free radical production in hypertension. J Hypertens (2002) 1.54
Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ. Mol Cell (2011) 1.52
Extracellular matrix, integrins, and growth factors as tailors of the stem cell niche. Curr Opin Cell Biol (2012) 1.51
Phosphoinositide 3-kinase gamma-deficient hearts are protected from the PAF-dependent depression of cardiac contractility. Cardiovasc Res (2003) 1.51
A leukemia-enriched cDNA microarray platform identifies new transcripts with relevance to the biology of pediatric acute lymphoblastic leukemia. Haematologica (2005) 1.50
Integrin signalling: the tug-of-war in heart hypertrophy. Cardiovasc Res (2006) 1.45
E-cadherin endocytosis regulates the activity of Rap1: a traffic light GTPase at the crossroads between cadherin and integrin function. J Cell Sci (2005) 1.45
Replacement of K-Ras with H-Ras supports normal embryonic development despite inducing cardiovascular pathology in adult mice. EMBO Rep (2005) 1.43
The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation. J Clin Invest (2012) 1.36
CD133+ renal progenitor cells contribute to tumor angiogenesis. Am J Pathol (2006) 1.36
Hemopexin therapy improves cardiovascular function by preventing heme-induced endothelial toxicity in mouse models of hemolytic diseases. Circulation (2013) 1.36
Enhanced splenomegaly and severe liver inflammation in haptoglobin/hemopexin double-null mice after acute hemolysis. Blood (2002) 1.34
Hemoglobin and heme scavenging. IUBMB Life (2005) 1.34
Gene expression profiling in dysferlinopathies using a dedicated muscle microarray. Hum Mol Genet (2002) 1.32
Extracellular vesicles as an emerging mechanism of cell-to-cell communication. Endocrine (2012) 1.32
p130Cas interacts with estrogen receptor alpha and modulates non-genomic estrogen signaling in breast cancer cells. J Cell Sci (2004) 1.29
Pattern recognition in gene expression profiling using DNA array: a comparative study of different statistical methods applied to cancer classification. Hum Mol Genet (2003) 1.29
Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma. J Exp Med (2005) 1.27
Denervation in murine fast-twitch muscle: short-term physiological changes and temporal expression profiling. Physiol Genomics (2005) 1.27
miR148b is a major coordinator of breast cancer progression in a relapse-associated microRNA signature by targeting ITGA5, ROCK1, PIK3CA, NRAS, and CSF1. FASEB J (2012) 1.27
Hemopexin prevents endothelial damage and liver congestion in a mouse model of heme overload. Am J Pathol (2008) 1.26
Adaptive and maladaptive hypertrophic pathways: points of convergence and divergence. Cardiovasc Res (2004) 1.25
Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrepresented upstream motifs. BMC Bioinformatics (2004) 1.25
Functional antagonism between Sall4 and Plzf defines germline progenitors. Cell Stem Cell (2012) 1.24
Human liver stem cell-derived microvesicles inhibit hepatoma growth in SCID mice by delivering antitumor microRNAs. Stem Cells (2012) 1.23
Beta-amyloid deposition in brain is enhanced in mouse models of arterial hypertension. Neurobiol Aging (2007) 1.23