Published in J Cell Physiol on November 01, 2005
Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics. Cancer Res (2009) 5.68
The eIF4E RNA regulon promotes the Akt signaling pathway. J Cell Biol (2008) 1.22
Akt inhibitor a-443654 interferes with mitotic progression by regulating aurora a kinase expression. Neoplasia (2008) 0.95
Apigenin promotes apoptosis, inhibits invasion and induces cell cycle arrest of T24 human bladder cancer cells. Cancer Cell Int (2013) 0.92
Arachidonoyl-phosphatidylcholine oscillates during the cell cycle and counteracts proliferation by suppressing Akt membrane binding. Proc Natl Acad Sci U S A (2013) 0.90
The PLK1 inhibitor GSK461364A is effective in poorly differentiated and anaplastic thyroid carcinoma cells, independent of the nature of their driver mutations. Thyroid (2013) 0.89
An IGF1/insulin receptor substrate-1 pathway stimulates a mitotic kinase (cdk1) in the uterine epithelium during the proliferative response to estradiol. J Endocrinol (2010) 0.84
Transcriptional activation of PRMT5 by NF-Y is required for cell growth and negatively regulated by the PKC/c-Fos signaling in prostate cancer cells. Biochim Biophys Acta (2014) 0.84
Immunolocalization of phospho-S6 kinases: a new way to detect mitosis in tissue sections and in cell culture. Histochem Cell Biol (2006) 0.82
Ellipticine derivative induces potent cytostatic effect in acute myeloid leukaemia cells. Invest New Drugs (2014) 0.81
Radiation-induced upregulation of telomerase activity escapes PI3-kinase inhibition in two malignant glioma cell lines. Int J Oncol (2013) 0.81
Enhanced clonogenic survival induced by protein tyrosine phosphatase (PTP) inhibition after Cr(VI) exposure is mediated by c-Raf and Ras activity. Cell Signal (2009) 0.80
Protein phosphatase magnesium dependent 1A (PPM1A) plays a role in the differentiation and survival processes of nerve cells. PLoS One (2012) 0.80
Inhibition of miR301 enhances Akt-mediated cell proliferation by accumulation of PTEN in nucleus and its effects on cell-cycle regulatory proteins. Oncotarget (2016) 0.78
Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation. Cell Metab (2017) 0.77
Mitochondrial Fragmentation Due to Inhibition of Fusion Increases Cyclin B through Mitochondrial Superoxide Radicals. PLoS One (2015) 0.77
Undecylprodigiosin induced apoptosis in P388 cancer cells is associated with its binding to ribosome. PLoS One (2013) 0.75
Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes. Nature (2005) 2.43
BTB domain-containing speckle-type POZ protein (SPOP) serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase. J Biol Chem (2006) 2.03
ISG15 and immune diseases. Biochim Biophys Acta (2010) 1.68
Versatile protein tag, SUMO: its enzymology and biological function. J Cell Physiol (2002) 1.64
Deubiquitinating enzymes as cellular regulators. J Biochem (2003) 1.60
Role of the GYVG pore motif of HslU ATPase in protein unfolding and translocation for degradation by HslV peptidase. J Biol Chem (2005) 1.53
Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex. Mol Cell Biol (2008) 1.52
p53-independent induction of G1 arrest and p21WAF1/CIP1 expression by ascofuranone, an isoprenoid antibiotic, through downregulation of c-Myc. Mol Cancer Ther (2010) 1.52
Roles of sumoylation of a reptin chromatin-remodelling complex in cancer metastasis. Nat Cell Biol (2006) 1.52
ERK-1/2 and p38 kinase oppositely regulate nitric oxide-induced apoptosis of chondrocytes in association with p53, caspase-3, and differentiation status. J Biol Chem (2001) 1.50
EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase complex. Mol Cell (2012) 1.48
A novel type of E3 ligase for the Ufm1 conjugation system. J Biol Chem (2009) 1.47
Mystery Case: pendular see-saw nystagmus as a delayed complication of traumatic brain injury. Neurology (2014) 1.39
The C-terminal tails of HslU ATPase act as a molecular switch for activation of HslV peptidase. J Biol Chem (2002) 1.39
ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway. EMBO Rep (2009) 1.30
1H-NMR-based metabolomics study of cerebral infarction. Stroke (2011) 1.26
Two novel ubiquitin-fold modifier 1 (Ufm1)-specific proteases, UfSP1 and UfSP2. J Biol Chem (2006) 1.26
p38 kinase regulates nitric oxide-induced apoptosis of articular chondrocytes by accumulating p53 via NFkappa B-dependent transcription and stabilization by serine 15 phosphorylation. J Biol Chem (2002) 1.21
The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice. Nat Commun (2011) 1.19
The active site of a lon protease from Methanococcus jannaschii distinctly differs from the canonical catalytic Dyad of Lon proteases. J Biol Chem (2004) 1.15
The effects of luteolin on osteoclast differentiation, function in vitro and ovariectomy-induced bone loss. J Nutr Biochem (2010) 1.13
SUMOylation of hnRNP-K is required for p53-mediated cell-cycle arrest in response to DNA damage. EMBO J (2012) 1.12
Chfr is linked to tumour metastasis through the downregulation of HDAC1. Nat Cell Biol (2009) 1.12
Methylation of the mouse DIx5 and Osx gene promoters regulates cell type-specific gene expression. Mol Cells (2006) 1.09
Genetic association of angiogenesis- and hypoxia-related gene polymorphisms with osteonecrosis of the femoral head. Exp Mol Med (2010) 1.09
Oligomeric structure of the ATP-dependent protease La (Lon) of Escherichia coli. Mol Cells (2006) 1.07
SUMO-specific protease SUSP4 positively regulates p53 by promoting Mdm2 self-ubiquitination. Nat Cell Biol (2006) 1.06
Structural basis for Ufm1 processing by UfSP1. J Biol Chem (2008) 1.04
SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells. Proc Natl Acad Sci U S A (2007) 1.03
Negative modulation of RXRalpha transcriptional activity by small ubiquitin-related modifier (SUMO) modification and its reversal by SUMO-specific protease SUSP1. J Biol Chem (2006) 1.02
Secretome analysis of human BMSCs and identification of SMOC1 as an important ECM protein in osteoblast differentiation. J Proteome Res (2010) 1.01
Cytotoxic and anti-inflammatory constituents from the seeds of Descurainia sophia. Arch Pharm Res (2013) 1.01
BMP-2-enhanced chondrogenesis involves p38 MAPK-mediated down-regulation of Wnt-7a pathway. Mol Cells (2006) 1.00
Filamin B serves as a molecular scaffold for type I interferon-induced c-Jun NH2-terminal kinase signaling pathway. Mol Biol Cell (2008) 0.98
Ethanol extract of Gleditsia sinensis thorn suppresses angiogenesis in vitro and in vivo. BMC Complement Altern Med (2012) 0.98
Antagonistic regulation of myogenesis by two deubiquitinating enzymes, UBP45 and UBP69. Proc Natl Acad Sci U S A (2002) 0.97
MMP-2 functions as a negative regulator of chondrogenic cell condensation via down-regulation of the FAK-integrin beta1 interaction. Dev Biol (2007) 0.96
Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15. J Clin Invest (2012) 0.96
Association of the OSCAR promoter polymorphism with BMD in postmenopausal women. J Bone Miner Res (2005) 0.95
Association study of semaphorin 7a (sema7a) polymorphisms with bone mineral density and fracture risk in postmenopausal Korean women. J Hum Genet (2005) 0.93
Control of adipogenesis by the SUMO-specific protease SENP2. Mol Cell Biol (2010) 0.93
Group IB secretory phospholipase A2 promotes matrix metalloproteinase-2-mediated cell migration via the phosphatidylinositol 3-kinase and Akt pathway. J Biol Chem (2004) 0.92
Proteomic profile of osteoclast membrane proteins: identification of Na+/H+ exchanger domain containing 2 and its role in osteoclast fusion. Proteomics (2008) 0.92
Peroxisome proliferator-activated receptor-gamma gene polymorphisms are not associated with osteonecrosis of the femoral head in the Korean population. Mol Cells (2007) 0.91
Decreased paraoxonase-1 activity is a risk factor for ischemic stroke in Koreans. Biochem Biophys Res Commun (2007) 0.91
Inactivation of NADP(+)-dependent isocitrate dehydrogenase by nitric oxide. Free Radic Biol Med (2002) 0.91
p38 kinase-dependent and -independent Inhibition of protein kinase C zeta and -alpha regulates nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes. J Biol Chem (2002) 0.90
Non-steroidal anti-inflammatory drugs inhibit nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes independent of cyclooxygenase activity. J Biol Chem (2003) 0.89
In Vivo Anti-tumor Effects of the Ethanol Extract of Gleditsia sinensis Thorns and Its Active Constituent, Cytochalasin H. Biol Pharm Bull (2015) 0.89
Akt signaling regulates actin organization via modulation of MMP-2 activity during chondrogenesis of chick wing limb bud mesenchymal cells. J Cell Biochem (2007) 0.89
TGF-beta3 inhibits chondrogenesis of cultured chick leg bud mesenchymal cells via downregulation of connexin 43 and integrin beta4. J Cell Physiol (2008) 0.89
Xpbx1b and Xmeis1b play a collaborative role in hindbrain and neural crest gene expression in Xenopus embryos. Proc Natl Acad Sci U S A (2002) 0.89
Association of a RUNX2 promoter polymorphism with bone mineral density in postmenopausal Korean women. Calcif Tissue Int (2009) 0.88
Distribution of TGF-beta isoforms and signaling intermediates in corneal fibrotic wound repair. J Cell Biochem (2009) 0.88
Significant association of SREBP-2 genetic polymorphisms with avascular necrosis in the Korean population. BMC Med Genet (2008) 0.88
Structure of ubiquitin-fold modifier 1-specific protease UfSP2. J Biol Chem (2011) 0.88
Gene Expression Profile of the A549 Human Non-Small Cell Lung Carcinoma Cell Line following Treatment with the Seeds of Descurainia sophia, a Potential Anticancer Drug. Evid Based Complement Alternat Med (2013) 0.88
Evaluation of solid free-form fabrication-based scaffolds seeded with osteoblasts and human umbilical vein endothelial cells for use in vivo osteogenesis. Tissue Eng Part A (2010) 0.88
Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome. Reprod Fertil Dev (2003) 0.88
Enhanced ex vivo expansion of human adipose tissue-derived mesenchymal stromal cells by fibroblast growth factor-2 and dexamethasone. Tissue Eng Part A (2009) 0.87
Binding of MG132 or deletion of the Thr active sites in HslV subunits increases the affinity of HslV protease for HslU ATPase and makes this interaction nucleotide-independent. J Biol Chem (2008) 0.87
Lack of association of MTHFR gene polymorphisms with the risk of osteonecrosis of the femoral head in a Korean population. Mol Cells (2010) 0.86
Chondrogenesis induced by actin cytoskeleton disruption is regulated via protein kinase C-dependent p38 mitogen-activated protein kinase signaling. J Cell Biochem (2003) 0.85
Effect of a peroxisome proliferator-activated receptor gamma sumoylation mutant on neointimal formation after balloon injury in rats. Atherosclerosis (2009) 0.85
Suppression of ADAM 10-induced Delta-1 shedding inhibits cell proliferation during the chondro-inhibitory action of TGF-beta3. Mol Cells (2007) 0.85
Methionine synthase reductase polymorphisms are associated with serum osteocalcin levels in postmenopausal women. Exp Mol Med (2006) 0.84
MYOD mediates skeletal myogenic differentiation of human amniotic fluid stem cells and regeneration of muscle injury. Stem Cell Res Ther (2013) 0.84
Wnt-5a is involved in TGF-beta3-stimulated chondrogenic differentiation of chick wing bud mesenchymal cells. Int J Biochem Cell Biol (2005) 0.84
Association of polymorphisms in the Interleukin 23 receptor gene with osteonecrosis of femoral head in Korean population. Exp Mol Med (2008) 0.84
Cell adhesion and proliferation evaluation of SFF-based biodegradable scaffolds fabricated using a multi-head deposition system. Biofabrication (2009) 0.84
Interleukin-1beta stimulates matrix metalloproteinase-2 expression via a prostaglandin E2-dependent mechanism in human chondrocytes. Exp Mol Med (2004) 0.83
Protein kinase C regulates the activity and stability of serotonin N-acetyltransferase. J Neurochem (2004) 0.83
Cytochalasin H, an active anti-angiogenic constituent of the ethanol extract of Gleditsia sinensis thorns. Biol Pharm Bull (2013) 0.82
Secretory phospholipase A2 promotes MMP-9-mediated cell death by degrading type I collagen via the ERK pathway at an early stage of chondrogenesis. Biol Cell (2009) 0.82
Associations of catalase gene polymorphisms with bone mineral density and bone turnover markers in postmenopausal women. J Med Genet (2007) 0.82
Gene expression profiling of oral epithelium during tooth development. Arch Oral Biol (2012) 0.82
Proliferation and osteoblastic differentiation of bone marrow stem cells: comparison of vertebral body and iliac crest. Eur Spine J (2010) 0.81
Association between PON1 5'-regulatory region polymorphisms, PON1 activity and ischemic stroke. Clin Biochem (2009) 0.81
HSD11B1 polymorphisms predicted bone mineral density and fracture risk in postmenopausal women without a clinically apparent hypercortisolemia. Bone (2009) 0.81
Roles of MMP/TIMP in regulating matrix swelling and cell migration during chick corneal development. J Cell Biochem (2007) 0.81
A Method for Assaying Deubiquitinating Enzymes. Biol Proced Online (1998) 0.81
Association of the adiponectin gene variations with risk of ischemic stroke in a Korean population. Yonsei Med J (2011) 0.81
Polymorphisms and haplotypes of integrinalpha1 (ITGA1) are associated with bone mineral density and fracture risk in postmenopausal Koreans. Bone (2007) 0.81
gp130 is important for the normal morphogenesis of Meckel's cartilage and subsequent mandibular development. Exp Mol Med (2007) 0.81
Akt as a mediator of secretory phospholipase A2 receptor-involved inducible nitric oxide synthase expression. J Immunol (2003) 0.81
HslVU ATP-dependent protease utilizes maximally six among twelve threonine active sites during proteolysis. J Biol Chem (2009) 0.81
MicroRNA-142-3p regulates TGF-β3-mediated region-dependent chondrogenesis by regulating ADAM9. Biochem Biophys Res Commun (2011) 0.81
Analysis of the soluble human tooth proteome and its ability to induce dentin/tooth regeneration. Tissue Eng Part A (2010) 0.81
Inhibitory effects of triptolide on titanium particle-induced osteolysis and receptor activator of nuclear factor-κB ligand-mediated osteoclast differentiation. Int Orthop (2014) 0.80
A novel PPARgamma agonist, KR62776, suppresses RANKL-induced osteoclast differentiation and activity by inhibiting MAP kinase pathways. Biochem Biophys Res Commun (2008) 0.80