Published in Genes Chromosomes Cancer on September 01, 2005
Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma. J Natl Cancer Inst (2008) 2.17
A novel role for mitochondria in regulating epigenetic modification in the nucleus. Cancer Biol Ther (2008) 2.03
Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis. Cell Res (2009) 1.70
Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck. Proc Natl Acad Sci U S A (2007) 1.68
Mitochondrial subversion in cancer. Cancer Prev Res (Phila) (2011) 1.54
Association of decreased mitochondrial DNA content with ovarian cancer progression. Br J Cancer (2006) 1.43
Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain. J Biol Chem (2010) 1.30
Mitochondrial DNA instability and metabolic shift in human cancers. Int J Mol Sci (2009) 1.29
Genetic insights into OXPHOS defect and its role in cancer. Biochim Biophys Acta (2010) 1.29
Mitochondrial DNA copy number and risk of gastric cancer: a report from the Shanghai Women's Health Study. Cancer Epidemiol Biomarkers Prev (2011) 1.20
Mitochondrial copy number is associated with colorectal cancer risk. Cancer Epidemiol Biomarkers Prev (2012) 1.19
The pseudo-mitochondrial genome influences mistakes in heteroplasmy interpretation. BMC Genomics (2006) 1.17
Cellular model of Warburg effect identifies tumor promoting function of UCP2 in breast cancer and its suppression by genipin. PLoS One (2011) 1.16
Mitochondrial DNA copy number and pancreatic cancer in the alpha-tocopherol beta-carotene cancer prevention study. Cancer Prev Res (Phila) (2011) 1.16
Mutations in mitochondrial DNA polymerase-gamma promote breast tumorigenesis. J Hum Genet (2009) 1.15
Tumorigenic transformation of human breast epithelial cells induced by mitochondrial DNA depletion. Cancer Biol Ther (2008) 1.15
Decreased mitochondrial DNA content in blood samples of patients with stage I breast cancer. BMC Cancer (2009) 1.14
Mitochondrial DNA copy number and risk of oral cancer: a report from Northeast India. PLoS One (2013) 1.14
Mitochondrial DNA copy number is associated with breast cancer risk. PLoS One (2013) 1.11
Mitochondrial DNA content and lung cancer risk in Xuan Wei, China. Lung Cancer (2008) 1.10
The mitochondrial DNA 4,977-bp deletion and its implication in copy number alteration in colorectal cancer. BMC Med Genet (2011) 1.10
Regulation of mitochondrial DNA content and cancer. Mitochondrion (2006) 1.07
Analysis of nuclear and mitochondrial genes in patients with pseudoexfoliation glaucoma. Mol Vis (2008) 1.05
Mitochondrial DNA polymorphism and risk of cancer. Methods Mol Biol (2009) 1.02
The awakening of an advanced malignant cancer: an insult to the mitochondrial genome. Biochim Biophys Acta (2011) 1.02
Quantitative analysis of mitochondrial DNA 4977-bp deletion in sporadic breast cancer and benign breast diseases. Breast Cancer Res Treat (2007) 1.01
Metabolic alterations in cancer cells and therapeutic implications. Chin J Cancer (2011) 0.96
Mitochondrial DNA alterations and mitochondrial dysfunction in the progression of hepatocellular carcinoma. World J Gastroenterol (2013) 0.95
High mitochondrial DNA copy number and bioenergetic function are associated with tumor invasion of esophageal squamous cell carcinoma cell lines. Int J Mol Sci (2012) 0.94
Mitochondrial DNA mutations in renal cell carcinomas revealed no general impact on energy metabolism. Br J Cancer (2006) 0.93
Leukocyte mitochondrial DNA alteration in systemic lupus erythematosus and its relevance to the susceptibility to lupus nephritis. Int J Mol Sci (2012) 0.93
Variable copy number of mitochondrial DNA (mtDNA) predicts worse prognosis in advanced gastric cancer patients. Diagn Pathol (2013) 0.92
Association of decreased mitochondrial DNA content with the progression of colorectal cancer. BMC Cancer (2013) 0.91
Mitochondrial-nuclear epistasis: implications for human aging and longevity. Ageing Res Rev (2010) 0.89
Sequence-based polymorphisms in the mitochondrial D-loop and potential SNP predictors for chronic dialysis. PLoS One (2012) 0.89
Mitochondrial DNA content varies with pathological characteristics of breast cancer. J Oncol (2011) 0.88
Mitochondrial mutations in adenoid cystic carcinoma of the salivary glands. PLoS One (2009) 0.87
Peripheral blood mitochondrial DNA copy number is associated with prostate cancer risk and tumor burden. PLoS One (2014) 0.87
Mitochondrial common deletion, a potential biomarker for cancer occurrence, is selected against in cancer background: a meta-analysis of 38 studies. PLoS One (2013) 0.84
Decreased mitochondrial DNA content in association with exposure to polycyclic aromatic hydrocarbons in house dust during wintertime: from a population enquiry to cell culture. PLoS One (2013) 0.83
The emergence of the mitochondrial genome as a partial regulator of nuclear function is providing new insights into the genetic mechanisms underlying age-related complex disease. Hum Genet (2013) 0.83
Somatic alterations in mitochondrial DNA and mitochondrial dysfunction in gastric cancer progression. World J Gastroenterol (2014) 0.82
Silencing of IkBβ mRNA causes disruption of mitochondrial retrograde signaling and suppression of tumor growth in vivo. Carcinogenesis (2012) 0.81
Mitochondrial genome regulates mitotic fidelity by maintaining centrosomal homeostasis. Cell Cycle (2014) 0.81
Peripheral blood mitochondrial DNA content, A10398G polymorphism, and risk of breast cancer in a Han Chinese population. Cancer Sci (2014) 0.79
Genetic characteristics of mitochondrial DNA was associated with colorectal carcinogenesis and its prognosis. PLoS One (2015) 0.79
Mitochondrial DNA 4977 bp Deletion in Chronic Cervicitis and Cervix Cancers. Balkan J Med Genet (2012) 0.79
Association of leukocyte mitochondrial DNA content with glioma risk: evidence from a Chinese case-control study. BMC Cancer (2014) 0.79
Mitochondrial DNA depletion sensitizes cancer cells to PARP inhibitors by translational and post-translational repression of BRCA2. Oncogenesis (2013) 0.79
Microhomology-mediated end joining is the principal mediator of double-strand break repair during mitochondrial DNA lesions. Mol Biol Cell (2015) 0.79
Role of Mitochondrial DNA Copy Number Alteration in Human Renal Cell Carcinoma. Int J Mol Sci (2016) 0.78
High leukocyte mtDNA content contributes to poor prognosis through ROS-mediated immunosuppression in hepatocellular carcinoma patients. Oncotarget (2016) 0.78
Role of mitochondrial dysfunction in cancer progression. Exp Biol Med (Maywood) (2016) 0.77
Common 4977 bp deletion and novel alterations in mitochondrial DNA in Vietnamese patients with breast cancer. Springerplus (2015) 0.77
Global genetic determinants of mitochondrial DNA copy number. PLoS One (2014) 0.77
Analysis of mitochondrial DNA in Tibetan gastric cancer patients at high altitude. Mol Clin Oncol (2015) 0.77
Mitochondrial DNA copy number in peripheral blood leukocytes and the aggressiveness of localized prostate cancer. Oncotarget (2015) 0.77
Mitochondrial DNA Content as Risk Factor for Bladder Cancer and Its Association with Mitochondrial DNA Polymorphisms. Cancer Prev Res (Phila) (2015) 0.76
Tipping the balance in the powerhouse of the cell to "protect" colorectal cancer. PLoS Genet (2012) 0.76
Increased Histone Deacetylase Activity Involved in the Suppressed Invasion of Cancer Cells Survived from ALA-Mediated Photodynamic Treatment. Int J Mol Sci (2015) 0.76
Mitochondrial DNA Polymerase POLG1 Disease Mutations and Germline Variants Promote Tumorigenic Properties. PLoS One (2015) 0.75
Mitochondrial DNA alterations in the progression of gastric carcinomas: unexplored issues and future research needs. World J Gastroenterol (2014) 0.75
Mitochondrial dysfunction enhances cisplatin resistance in human gastric cancer cells via the ROS-activated GCN2-eIF2α-ATF4-xCT pathway. Oncotarget (2016) 0.75
AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway. Int J Oncol (2016) 0.75
Elevated Mitochondrial DNA Copy Number in Peripheral Blood and Tissue Predict the Opposite Outcome of Cancer: A Meta-Analysis. Sci Rep (2016) 0.75
Mitochondriome and cholangiocellular carcinoma. PLoS One (2014) 0.75
Mitochondrial determinants of cancer health disparities. Semin Cancer Biol (2017) 0.75
Defining the momiome: Promiscuous information transfer by mobile mitochondria and the mitochondrial genome. Semin Cancer Biol (2017) 0.75
Nodal dissection for patients with gastric cancer: a randomised controlled trial. Lancet Oncol (2006) 4.38
Quantification of plasma Epstein-Barr virus DNA in patients with advanced nasopharyngeal carcinoma. N Engl J Med (2004) 3.19
Mitochondrial biogenesis and mitochondrial DNA maintenance of mammalian cells under oxidative stress. Int J Biochem Cell Biol (2005) 2.91
Oxidative stress-related alteration of the copy number of mitochondrial DNA in human leukocytes. Free Radic Res (2003) 2.70
Coordinated changes of mitochondrial biogenesis and antioxidant enzymes during osteogenic differentiation of human mesenchymal stem cells. Stem Cells (2008) 2.34
Attenuation of oxidative stress after varicocelectomy in subfertile patients with varicocele. J Urol (2007) 2.20
The anti-inflammatory potential of berberine in vitro and in vivo. Cancer Lett (2004) 2.15
miR-21 microRNA expression in human gastric carcinomas and its clinical association. Anticancer Res (2008) 2.09
Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma. Mutat Res (2004) 2.01
Mitochondrial genome instability and mtDNA depletion in human cancers. Ann N Y Acad Sci (2005) 1.97
Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging. Exp Biol Med (Maywood) (2002) 1.96
Prognostic variables in thoracic esophageal squamous cell carcinoma. Ann Thorac Surg (2009) 1.81
Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer. Genes Chromosomes Cancer (2006) 1.77
Non-Hodgkin's lymphoma presenting as a large chest wall mass. Ann Thorac Surg (2006) 1.77
Osteopontin promotes integrin activation through outside-in and inside-out mechanisms: OPN-CD44V interaction enhances survival in gastrointestinal cancer cells. Cancer Res (2007) 1.73
Fine tuning the energetics of excited-state intramolecular proton transfer (ESIPT): white light generation in a single ESIPT system. J Am Chem Soc (2011) 1.70
The activated Notch1 signal pathway is associated with gastric cancer progression through cyclooxygenase-2. Cancer Res (2009) 1.62
Small cell carcinoma of the esophagus: a report of 16 cases from a single institution and literature review. Ann Thorac Surg (2011) 1.62
Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice. Genes Dev (2009) 1.61
Correlation and comparison of the model for end-stage liver disease, portal pressure, and serum sodium for outcome prediction in patients with liver cirrhosis. J Clin Gastroenterol (2007) 1.60
Is the corrected-creatinine model for end-stage liver disease a feasible strategy to adjust gender difference in organ allocation for liver transplantation? Transplantation (2007) 1.56
Clinical implications of chromosomal abnormalities in gastric adenocarcinomas. Genes Chromosomes Cancer (2002) 1.52
Temsirolimus enhances the efficacy of cetuximab in colon cancer through a CIP2A-dependent mechanism. J Cancer Res Clin Oncol (2014) 1.49
Genetic analysis in Leber's hereditary optic neuropathy using the comparative genomic hybridization technique. Clin Experiment Ophthalmol (2003) 1.45
Oxidative stress, mitochondrial DNA mutation, and apoptosis in aging. Exp Biol Med (Maywood) (2007) 1.45
Clinical significance of AXL kinase family in gastric cancer. Anticancer Res (2002) 1.40
Leber's hereditary optic neuropathy: a multifactorial disease. Prog Retin Eye Res (2006) 1.37
Mitochondria and aging. Adv Exp Med Biol (2012) 1.37
Identification of a novel cell cycle regulated gene, HURP, overexpressed in human hepatocellular carcinoma. Oncogene (2003) 1.36
8-hydroxy-2'-deoxyguanosine in leukocyte DNA of spermatic vein as a biomarker of oxidative stress in patients with varicocele. J Urol (2004) 1.34
Oxidative stress response elicited by mitochondrial dysfunction: implication in the pathophysiology of aging. Exp Biol Med (Maywood) (2013) 1.30
Mitochondrial DNA instability and metabolic shift in human cancers. Int J Mol Sci (2009) 1.29
Low copy number and low oxidative damage of mitochondrial DNA are associated with tumor progression in lung cancer tissues after neoadjuvant chemotherapy. Interact Cardiovasc Thorac Surg (2008) 1.28
Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver. Hepatology (2007) 1.23
The -251T allele of the interleukin-8 promoter is associated with increased risk of gastric carcinoma featuring diffuse-type histopathology in Chinese population. Clin Cancer Res (2005) 1.22
Inhibition of lung cancer cell growth by quercetin glucuronides via G2/M arrest and induction of apoptosis. Drug Metab Dispos (2005) 1.21
Differentiation of apoptosis from necrosis by dynamic changes of reduced nicotinamide adenine dinucleotide fluorescence lifetime in live cells. J Biomed Opt (2008) 1.19
Excited-state intramolecular proton transfer molecules bearing o-hydroxy analogues of green fluorescent protein chromophore. J Org Chem (2011) 1.18
AMPK-mediated increase of glycolysis as an adaptive response to oxidative stress in human cells: implication of the cell survival in mitochondrial diseases. Biochim Biophys Acta (2011) 1.18
Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence. J Biomed Sci (2002) 1.18
Intravenous iron exacerbates oxidative DNA damage in peripheral blood lymphocytes in chronic hemodialysis patients. J Am Soc Nephrol (2008) 1.17
Analysis of the seventh edition of American Joint Committee on colon cancer staging. Int J Colorectal Dis (2011) 1.17
Expression of beta-F1-ATPase and mitochondrial transcription factor A and the change in mitochondrial DNA content in colorectal cancer: clinical data analysis and evidence from an in vitro study. Int J Colorectal Dis (2008) 1.16
Relationship between genetic alterations and prognosis in sporadic colorectal cancer. Int J Cancer (2006) 1.16
Esophagogastric junction adenocarcinoma according to Siewert classification in Taiwan. Ann Surg Oncol (2009) 1.12
Comparison of the survival difference between AJCC 6th and 7th editions for gastric cancer patients. World J Surg (2011) 1.11
Oxidative stress-induced depolymerization of microtubules and alteration of mitochondrial mass in human cells. Ann N Y Acad Sci (2005) 1.10
Enhanced oxidative stress and aberrant mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells during methamphetamine induced apoptosis. Toxicol Appl Pharmacol (2007) 1.10
Early postoperative CEA level is a better prognostic indicator than is preoperative CEA level in predicting prognosis of patients with curable colorectal cancer. Int J Colorectal Dis (2011) 1.09
Rab5A is associated with axillary lymph node metastasis in breast cancer patients. Cancer Sci (2011) 1.09
Molecular Mechanisms of UV-Induced Apoptosis and Its Effects on Skin Residential Cells: The Implication in UV-Based Phototherapy. Int J Mol Sci (2013) 1.09
Association of the Y402H polymorphism in complement factor H gene and neovascular age-related macular degeneration in Chinese patients. Invest Ophthalmol Vis Sci (2006) 1.09
Prognostic significance of multiple molecular markers for patients with stage II colorectal cancer undergoing curative resection. Ann Surg (2007) 1.09
Initial experience of robotic gastrectomy and comparison with open and laparoscopic gastrectomy for gastric cancer. J Gastrointest Surg (2012) 1.08
Increased expression of amyloid precursor protein in oral squamous cell carcinoma. Int J Cancer (2004) 1.07
Activation of the Notch1/STAT3/Twist signaling axis promotes gastric cancer progression. Carcinogenesis (2012) 1.07
Notch2-induced COX-2 expression enhancing gastric cancer progression. Mol Carcinog (2011) 1.07
Somatic mutations of mitochondrial DNA in aging and cancer progression. Ageing Res Rev (2010) 1.06
Multiplex amplified product-length polymorphism analysis of 36 mitochondrial single-nucleotide polymorphisms for haplogrouping of East Asian populations. Electrophoresis (2005) 1.06
The emerging role of SOX2 in cell proliferation and survival and its crosstalk with oncogenic signaling in lung cancer. Stem Cells (2013) 1.05
Protein tyrosine-phosphatase expression profiling in gastric cancer tissues. Cancer Lett (2005) 1.05
The role of mitochondrial DNA alterations in esophageal squamous cell carcinomas. J Thorac Cardiovasc Surg (2009) 1.05
Rho/Rhotekin-mediated NF-kappaB activation confers resistance to apoptosis. Oncogene (2004) 1.04
Respiratory function decline and DNA mutation in mitochondria, oxidative stress and altered gene expression during aging. Chang Gung Med J (2009) 1.04
CIP2A is a predictor of poor prognosis in colon cancer. J Gastrointest Surg (2012) 1.03
Tumor size as a prognostic factor in resected small hepatocellular carcinoma: a controversy revisited. J Gastroenterol Hepatol (2011) 1.03
Clinicopathologic significance of leptin and leptin receptor expressions in papillary thyroid carcinoma. Surgery (2009) 1.03
Mitochondrial bioenergetic function and metabolic plasticity in stem cell differentiation and cellular reprogramming. Biochim Biophys Acta (2011) 1.02
SOCS6, down-regulated in gastric cancer, inhibits cell proliferation and colony formation. Cancer Lett (2009) 1.02
Increase of oxidative stress in human sperm with lower motility. Fertil Steril (2007) 1.02
Downregulation of tumor suppressor MBP-1 by microRNA-363 in gastric carcinogenesis. Carcinogenesis (2013) 1.02
IL-6 enriched lung cancer stem-like cell population by inhibition of cell cycle regulators via DNMT1 upregulation. Int J Cancer (2014) 1.02
Association of mitochondrial deoxyribonucleic acid 16189 variant (T->C transition) with metabolic syndrome in Chinese adults. J Clin Endocrinol Metab (2005) 1.02
Mitochondria-mediated caspase-independent apoptosis induced by cadmium in normal human lung cells. J Cell Biochem (2003) 1.01
Panax notoginseng saponins attenuate atherosclerosis in rats by regulating the blood lipid profile and an anti-inflammatory action. Clin Exp Pharmacol Physiol (2008) 1.01
SDF-1alpha G801A polymorphism predicts lymph node metastasis in stage T3 colorectal cancer. Ann Surg Oncol (2009) 1.00
The model for end-stage liver disease based cancer staging systems are better prognostic models for hepatocellular carcinoma: a prospective sequential survey. Am J Gastroenterol (2007) 1.00
Response to the increase of oxidative stress and mutation of mitochondrial DNA in aging. Biochim Biophys Acta (2009) 1.00
Mediating of caspase-independent apoptosis by cadmium through the mitochondria-ROS pathway in MRC-5 fibroblasts. J Cell Biochem (2004) 1.00
Oxidative-stress-related changes in the livers of bile-duct-ligated rats. J Biomed Sci (2003) 1.00
Aberrant methylation of EDNRB and p16 genes in hepatocellular carcinoma (HCC) in Taiwan. Oncol Rep (2006) 0.99
Peripheral blood mitochondrial DNA content and dysregulation of glucose metabolism. Diabetes Res Clin Pract (2008) 0.99
BRAF mutation is a prognostic biomarker for colorectal liver metastasectomy. J Surg Oncol (2012) 0.99