Published in Stem Cells on December 01, 2013
SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells. Oncogene (2014) 1.23
Cancer stem cells, cancer cell plasticity and radiation therapy. Semin Cancer Biol (2014) 1.08
SOX2 and cancer: current research and its implications in the clinic. Clin Transl Med (2014) 1.06
Hedgehog pathway maintains cell survival under stress conditions, and drives drug resistance in lung adenocarcinoma. Oncotarget (2016) 0.84
SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma. Sci Rep (2016) 0.84
YAP1 Regulates OCT4 Activity and SOX2 Expression to Facilitate Self-Renewal and Vascular Mimicry of Stem-Like Cells. Stem Cells (2015) 0.81
Novel peptides suppress VEGFR-3 activity and antagonize VEGFR-3-mediated oncogenic effects. Oncotarget (2014) 0.81
Association of SOX2 and Nestin DNA amplification and protein expression with clinical features and overall survival in non-small cell lung cancer: A systematic review and meta-analysis. Oncotarget (2016) 0.80
The prognostic value of whole blood SOX2, NANOG and OCT4 mRNA expression in advanced small-cell lung cancer. Radiol Oncol (2016) 0.79
microRNA-625 inhibits tumorigenicity by suppressing proliferation, migration and invasion in malignant melanoma. Oncotarget (2017) 0.79
Inhibition of mutant EGFR in lung cancer cells triggers SOX2-FOXO6-dependent survival pathways. Elife (2015) 0.78
SOX2 functions as a molecular rheostat to control the growth, tumorigenicity and drug responses of pancreatic ductal adenocarcinoma cells. Oncotarget (2016) 0.77
Intracellular signals of lung cancer cells as possible therapeutic targets. Cancer Sci (2015) 0.77
Sox2-dependent inhibition of p21 is associated with poor prognosis of endometrial cancer. Cancer Sci (2017) 0.76
The role of SOX-2 on the survival of patients with non-small cell lung cancer. J Thorac Dis (2015) 0.76
Clinicopathological significance of cancer stem-like cell markers in high-grade neuroendocrine carcinoma of the lung. J Cancer Res Clin Oncol (2015) 0.76
SSA-ME Detection of cancer driver genes using mutual exclusivity by small subnetwork analysis. Sci Rep (2016) 0.75
Inactivation of p38 MAPK contributes to stem cell-like properties of non-small cell lung cancer. Oncotarget (2017) 0.75
SOX2 and Rb1 in esophageal small-cell carcinoma: their possible involvement in pathogenesis. Mod Pathol (2017) 0.75
Enhanced therapeutic effect of an antiangiogenesis peptide on lung cancer in vivo combined with salmonella VNP20009 carrying a Sox2 shRNA construct. J Exp Clin Cancer Res (2016) 0.75
Oncogenesis and induced pluripotency - commonalities of signalling pathways. Contemp Oncol (Pozn) (2015) 0.75
Oncogenic Sox2 regulates and cooperates with VRK1 in cell cycle progression and differentiation. Sci Rep (2016) 0.75
The converging roles of BRD4 and gene transcription in pluripotency and oncogenesis. RNA Dis (2015) 0.75
Endocrine Therapy of Estrogen Receptor-Positive Breast Cancer Cells: Early Differential Effects on Stem Cell Markers. Front Oncol (2017) 0.75
Quantification of plasma Epstein-Barr virus DNA in patients with advanced nasopharyngeal carcinoma. N Engl J Med (2004) 3.19
Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation. Cancer Res (2010) 3.18
Mitochondrial biogenesis and mitochondrial DNA maintenance of mammalian cells under oxidative stress. Int J Biochem Cell Biol (2005) 2.91
Oxidative stress-related alteration of the copy number of mitochondrial DNA in human leukocytes. Free Radic Res (2003) 2.70
Coordinated changes of mitochondrial biogenesis and antioxidant enzymes during osteogenic differentiation of human mesenchymal stem cells. Stem Cells (2008) 2.34
Stem cell therapy for liver disease: parameters governing the success of using bone marrow mesenchymal stem cells. Gastroenterology (2008) 2.31
Attenuation of oxidative stress after varicocelectomy in subfertile patients with varicocele. J Urol (2007) 2.20
Expression of axl in lung adenocarcinoma and correlation with tumor progression. Neoplasia (2005) 2.04
Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma. Mutat Res (2004) 2.01
Mitochondrial DNA mutations and mitochondrial DNA depletion in gastric cancer. Genes Chromosomes Cancer (2005) 1.99
Mitochondrial genome instability and mtDNA depletion in human cancers. Ann N Y Acad Sci (2005) 1.97
EGFR promotes lung tumorigenesis by activating miR-7 through a Ras/ERK/Myc pathway that targets the Ets2 transcriptional repressor ERF. Cancer Res (2010) 1.95
Prognostic variables in thoracic esophageal squamous cell carcinoma. Ann Thorac Surg (2009) 1.81
Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer. Genes Chromosomes Cancer (2006) 1.77
Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice. Genes Dev (2009) 1.61
Use of arsenic-induced palmoplantar hyperkeratosis and skin cancers to predict risk of subsequent internal malignancy. Am J Epidemiol (2013) 1.61
Genetic analysis in Leber's hereditary optic neuropathy using the comparative genomic hybridization technique. Clin Experiment Ophthalmol (2003) 1.45
Oxidative stress, mitochondrial DNA mutation, and apoptosis in aging. Exp Biol Med (Maywood) (2007) 1.45
Peritoneal papillary serous cystadenocarcinoma at a previous laparoscopic trocar site. Taiwan J Obstet Gynecol (2012) 1.39
Upregulation of SOX9 in lung adenocarcinoma and its involvement in the regulation of cell growth and tumorigenicity. Clin Cancer Res (2010) 1.39
Antitumor and antimetastatic activity of IL-23. J Immunol (2003) 1.38
Leber's hereditary optic neuropathy: a multifactorial disease. Prog Retin Eye Res (2006) 1.37
Mitochondria and aging. Adv Exp Med Biol (2012) 1.37
Biomarkers of exposure, effect, and susceptibility of arsenic-induced health hazards in Taiwan. Toxicol Appl Pharmacol (2005) 1.35
8-hydroxy-2'-deoxyguanosine in leukocyte DNA of spermatic vein as a biomarker of oxidative stress in patients with varicocele. J Urol (2004) 1.34
Oxidative stress response elicited by mitochondrial dysfunction: implication in the pathophysiology of aging. Exp Biol Med (Maywood) (2013) 1.30
Mitochondrial DNA instability and metabolic shift in human cancers. Int J Mol Sci (2009) 1.29
Low copy number and low oxidative damage of mitochondrial DNA are associated with tumor progression in lung cancer tissues after neoadjuvant chemotherapy. Interact Cardiovasc Thorac Surg (2008) 1.28
Tumor-associated antigen L6 and the invasion of human lung cancer cells. Clin Cancer Res (2003) 1.21
Inhibition of lung cancer cell growth by quercetin glucuronides via G2/M arrest and induction of apoptosis. Drug Metab Dispos (2005) 1.21
Differentiation of apoptosis from necrosis by dynamic changes of reduced nicotinamide adenine dinucleotide fluorescence lifetime in live cells. J Biomed Opt (2008) 1.19
CD13 (aminopeptidase N) can associate with tumor-associated antigen L6 and enhance the motility of human lung cancer cells. Int J Cancer (2005) 1.18
AMPK-mediated increase of glycolysis as an adaptive response to oxidative stress in human cells: implication of the cell survival in mitochondrial diseases. Biochim Biophys Acta (2011) 1.18
Up-regulation of vascular endothelial growth factor C in breast cancer cells by heregulin-beta 1. A critical role of p38/nuclear factor-kappa B signaling pathway. J Biol Chem (2002) 1.18
Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence. J Biomed Sci (2002) 1.18
Intravenous iron exacerbates oxidative DNA damage in peripheral blood lymphocytes in chronic hemodialysis patients. J Am Soc Nephrol (2008) 1.17
HCMV IE2-mediated inhibition of HAT activity downregulates p53 function. EMBO J (2004) 1.17
Prognosis of non-small cell lung cancer patients by detecting circulating cancer cells in the peripheral blood with multiple marker genes. Clin Cancer Res (2005) 1.17
hNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencing. J Clin Invest (2010) 1.11
Oxidative stress-induced depolymerization of microtubules and alteration of mitochondrial mass in human cells. Ann N Y Acad Sci (2005) 1.10
MicroRNA-210 targets antiapoptotic Bcl-2 expression and mediates hypoxia-induced apoptosis of neuroblastoma cells. Arch Toxicol (2012) 1.10
Molecular Mechanisms of UV-Induced Apoptosis and Its Effects on Skin Residential Cells: The Implication in UV-Based Phototherapy. Int J Mol Sci (2013) 1.09
Association of the Y402H polymorphism in complement factor H gene and neovascular age-related macular degeneration in Chinese patients. Invest Ophthalmol Vis Sci (2006) 1.09
Effect of plasma homocysteine level and urinary monomethylarsonic acid on the risk of arsenic-associated carotid atherosclerosis. Toxicol Appl Pharmacol (2006) 1.07
Targeting cancer stem cells: emerging role of Nanog transcription factor. Onco Targets Ther (2013) 1.06
Multiplex amplified product-length polymorphism analysis of 36 mitochondrial single-nucleotide polymorphisms for haplogrouping of East Asian populations. Electrophoresis (2005) 1.06
Role of angiogenic and non-angiogenic mechanisms in oral squamous cell carcinoma: correlation with histologic differentiation and tumor progression. J Oral Pathol Med (2004) 1.06
The role of mitochondrial DNA alterations in esophageal squamous cell carcinomas. J Thorac Cardiovasc Surg (2009) 1.05
MAD2B, a novel TCF4-binding protein, modulates TCF4-mediated epithelial-mesenchymal transdifferentiation. J Biol Chem (2009) 1.03
Mitochondrial bioenergetic function and metabolic plasticity in stem cell differentiation and cellular reprogramming. Biochim Biophys Acta (2011) 1.02
Increase of oxidative stress in human sperm with lower motility. Fertil Steril (2007) 1.02
Association of mitochondrial deoxyribonucleic acid 16189 variant (T->C transition) with metabolic syndrome in Chinese adults. J Clin Endocrinol Metab (2005) 1.02
Mitochondria-mediated caspase-independent apoptosis induced by cadmium in normal human lung cells. J Cell Biochem (2003) 1.01
A novel predictive score for hepatocellular carcinoma development in patients with chronic hepatitis C after sustained response to pegylated interferon and ribavirin combination therapy. J Antimicrob Chemother (2012) 1.01
Cyclooxygenase-1 and bicistronic cyclooxygenase-1/prostacyclin synthase gene transfer protect against ischemic cerebral infarction. Circulation (2002) 1.00
Surface analysis and corrosion resistance of different stainless steel orthodontic brackets in artificial saliva. Angle Orthod (2006) 1.00
Response to the increase of oxidative stress and mutation of mitochondrial DNA in aging. Biochim Biophys Acta (2009) 1.00
Resveratrol induces FasL-related apoptosis through Cdc42 activation of ASK1/JNK-dependent signaling pathway in human leukemia HL-60 cells. Carcinogenesis (2004) 1.00
Can we predict pathologic complete response before surgery for locally advanced rectal cancer treated with preoperative chemoradiation therapy? Int J Colorectal Dis (2011) 1.00
Mediating of caspase-independent apoptosis by cadmium through the mitochondria-ROS pathway in MRC-5 fibroblasts. J Cell Biochem (2004) 1.00
Oxidative-stress-related changes in the livers of bile-duct-ligated rats. J Biomed Sci (2003) 1.00
Arsenic in drinking water and risk of urinary tract cancer: a follow-up study from northeastern Taiwan. Cancer Epidemiol Biomarkers Prev (2010) 1.00
Peripheral blood mitochondrial DNA content and dysregulation of glucose metabolism. Diabetes Res Clin Pract (2008) 0.99
Comparative study of conventional colonoscopy, magnifying chromoendoscopy, and magnifying narrow-band imaging systems in the differential diagnosis of small colonic polyps between trainee and experienced endoscopist. Int J Colorectal Dis (2009) 0.99
Two non-homologous brain diseases-related genes, SERPINI1 and PDCD10, are tightly linked by an asymmetric bidirectional promoter in an evolutionarily conserved manner. BMC Mol Biol (2007) 0.98
Recurrence and poor prognosis following resection of small hepatitis B-related hepatocellular carcinoma lesions are associated with aberrant tumor expression profiles of glypican 3 and osteopontin. Ann Surg Oncol (2011) 0.98
A persistent level of Cisd2 extends healthy lifespan and delays aging in mice. Hum Mol Genet (2012) 0.97
Human cytomegalovirus UL76 encodes a novel virion-associated protein that is able to inhibit viral replication. J Virol (2004) 0.97
Metabolic reprogramming orchestrates cancer stem cell properties in nasopharyngeal carcinoma. Cell Cycle (2015) 0.97
Mitochondrial dysfunction in insulin insensitivity: implication of mitochondrial role in type 2 diabetes. Ann N Y Acad Sci (2010) 0.96
GT-repeat polymorphism in the heme oxygenase-1 gene promoter and the risk of carotid atherosclerosis related to arsenic exposure. J Biomed Sci (2010) 0.96
Inhibition of invasion and angiogenesis by zinc-chelating agent disulfiram. Mol Pharmacol (2003) 0.96
Reduced nicotinamide adenine dinucleotide fluorescence lifetime separates human mesenchymal stem cells from differentiated progenies. J Biomed Opt (2008) 0.96
Regulation of mitochondrial F(o)F(1)ATPase activity by Sirt3-catalyzed deacetylation and its deficiency in human cells harboring 4977bp deletion of mitochondrial DNA. Biochim Biophys Acta (2012) 0.96
Inhibitory effects of hypoxia on metabolic switch and osteogenic differentiation of human mesenchymal stem cells. Stem Cells (2013) 0.96
Resveratrol Impedes the Stemness, Epithelial-Mesenchymal Transition, and Metabolic Reprogramming of Cancer Stem Cells in Nasopharyngeal Carcinoma through p53 Activation. Evid Based Complement Alternat Med (2013) 0.95
Somatic mutations in mitochondrial genome and their potential roles in the progression of human gastric cancer. Biochim Biophys Acta (2009) 0.95
Aberrant cell proliferation by enhanced mitochondrial biogenesis via mtTFA in arsenical skin cancers. Am J Pathol (2011) 0.95
Increase in oxidative damage to lipids and proteins in skeletal muscle of uremic patients. Free Radic Res (2002) 0.95
Mitochondrial dysfunction leads to impairment of insulin sensitivity and adiponectin secretion in adipocytes. FEBS J (2013) 0.95
Upregulation of mitochondrial function and antioxidant defense in the differentiation of stem cells. Biochim Biophys Acta (2009) 0.95
High mitochondrial DNA copy number and bioenergetic function are associated with tumor invasion of esophageal squamous cell carcinoma cell lines. Int J Mol Sci (2012) 0.94
Shortening of microsatellite deoxy(CA) repeats involved in GL331-induced down-regulation of matrix metalloproteinase-9 gene expression. Biochem Biophys Res Commun (2003) 0.94
Repeated ovarian stimulations induce oxidative damage and mitochondrial DNA mutations in mouse ovaries. Ann N Y Acad Sci (2005) 0.94
Alteration of the copy number of mitochondrial DNA in leukocytes of patients with hyperlipidemia. Ann N Y Acad Sci (2005) 0.93
Leukocyte mitochondrial DNA alteration in systemic lupus erythematosus and its relevance to the susceptibility to lupus nephritis. Int J Mol Sci (2012) 0.93
Evaluation of cytokeratin-19 mRNA as a tumor marker in the peripheral blood of nasopharyngeal carcinoma patients receiving concurrent chemoradiotherapy. Int J Cancer (2002) 0.93
Somatic mutations of mitochondrial genome in hepatocellular carcinoma. Mitochondrion (2009) 0.93
A common mitochondrial DNA variant and increased body mass index as associated factors for development of type 2 diabetes: Additive effects of genetic and environmental factors. J Clin Endocrinol Metab (2006) 0.93
Analysis of the nucleoside triphosphatase, RNA triphosphatase, and unwinding activities of the helicase domain of dengue virus NS3 protein. FEBS Lett (2009) 0.92
Mitochondrial DNA mutation-elicited oxidative stress, oxidative damage, and altered gene expression in cultured cells of patients with MERRF syndrome. Mol Neurobiol (2010) 0.92
Multiple rearrangements of mitochondrial DNA in unfertilized human oocytes. Fertil Steril (2002) 0.92
Age-associated decrease of oxidative repair enzymes, human 8-oxoguanine DNA glycosylases (hOgg1), in human aging. J Radiat Res (2003) 0.92