Published in Pigment Cell Res on June 01, 2005
Mitf regulation of Dia1 controls melanoma proliferation and invasiveness. Genes Dev (2006) 2.87
Three-dimensional context regulation of metastasis. Clin Exp Metastasis (2008) 2.49
Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells. J Cell Biol (2006) 1.86
Cancer stem cells and human malignant melanoma. Pigment Cell Melanoma Res (2008) 1.65
Oncogenic B-RAF(V600E) signaling induces the T-Box3 transcriptional repressor to repress E-cadherin and enhance melanoma cell invasion. J Invest Dermatol (2012) 1.63
Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma. J Exp Med (2009) 1.59
Nanotechnology-based drug delivery systems. J Occup Med Toxicol (2007) 1.50
Melanoma miRNA trafficking controls tumour primary niche formation. Nat Cell Biol (2016) 1.49
NRG1 / ERBB3 signaling in melanocyte development and melanoma: inhibition of differentiation and promotion of proliferation. Pigment Cell Melanoma Res (2009) 1.45
Integrin targeted delivery of chemotherapeutics. Theranostics (2011) 1.42
Cell-extracellular matrix interactions in normal and diseased skin. Cold Spring Harb Perspect Biol (2011) 1.37
The secreted metalloprotease ADAMTS20 is required for melanoblast survival. PLoS Genet (2008) 1.34
Intravital imaging illuminates transforming growth factor beta signaling switches during metastasis. Cancer Res (2010) 1.18
Transmembrane potential of GlyCl-expressing instructor cells induces a neoplastic-like conversion of melanocytes via a serotonergic pathway. Dis Model Mech (2010) 1.17
Fibroblasts contribute to melanoma tumor growth and drug resistance. Mol Pharm (2011) 1.17
KLF6 Gene and early melanoma development in a collagen I-rich extracellular environment. J Natl Cancer Inst (2010) 1.14
Skin melanocytes: biology and development. Postepy Dermatol Alergol (2013) 1.14
Prognostic significance of cadherin-based adhesion molecules in cutaneous malignant melanoma. Cancer Epidemiol Biomarkers Prev (2008) 1.10
Reduced expression of autotaxin predicts survival in uveal melanoma. Br J Ophthalmol (2007) 1.10
Organotypic models of metastasis: A three-dimensional culture mimicking the human peritoneum and omentum for the study of the early steps of ovarian cancer metastasis. Cancer Treat Res (2009) 1.10
Modulation of extracellular matrix/adhesion molecule expression by BRG1 is associated with increased melanoma invasiveness. Mol Cancer (2010) 1.10
Melanophore migration and survival during zebrafish adult pigment stripe development require the immunoglobulin superfamily adhesion molecule Igsf11. PLoS Genet (2012) 1.08
Gpnmb is a melanosome-associated glycoprotein that contributes to melanocyte/keratinocyte adhesion in a RGD-dependent fashion. Exp Dermatol (2009) 1.07
Melanocyte receptors: clinical implications and therapeutic relevance. Dermatol Clin (2007) 1.01
Keratinocyte-derived laminin-332 promotes adhesion and migration in melanocytes and melanoma. J Biol Chem (2011) 0.99
Artificial skin in perspective: concepts and applications. Pigment Cell Melanoma Res (2010) 0.95
Tumor-promoting role of signal transducer and activator of transcription (Stat)1 in late-stage melanoma growth. Clin Exp Metastasis (2010) 0.94
The role of the hippo pathway in melanocytes and melanoma. Front Oncol (2013) 0.90
Matrix metalloproteinase-2 promotes αvβ3 integrin-mediated adhesion and migration of human melanoma cells by cleaving fibronectin. PLoS One (2012) 0.89
GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation. J Invest Dermatol (2012) 0.87
Expression and function of the kallikrein-related peptidase 6 in the human melanoma microenvironment. J Invest Dermatol (2011) 0.87
Melanoma progression exhibits a significant impact on connexin expression patterns in the epidermal tumor microenvironment. Histochem Cell Biol (2009) 0.85
Modeling Melanoma In Vitro and In Vivo. Healthcare (Basel) (2013) 0.85
Matricellular proteins produced by melanocytes and melanomas: in search for functions. Cancer Microenviron (2008) 0.84
MicroRNA in Melanoma. Ochsner J (2010) 0.84
Capturing the biological impact of CDKN2A and MC1R genes as an early predisposing event in melanoma and non melanoma skin cancer. Oncotarget (2014) 0.84
The clinicopathological and gene expression patterns associated with ulceration of primary melanoma. Pigment Cell Melanoma Res (2014) 0.83
Delivery of interleukin-15 to B16 melanoma by electroporation leads to tumor regression and long-term survival. Technol Cancer Res Treat (2013) 0.82
Stichopin-containing nerves and secretory cells specific to connective tissues of the sea cucumber. Proc Biol Sci (2007) 0.82
Gene network analyses point to the importance of human tissue kallikreins in melanoma progression. BMC Med Genomics (2011) 0.81
Morphology of melanocytic lesions in situ. Sci Rep (2014) 0.81
The use of an in vitro 3D melanoma model to predict in vivo plasmid transfection using electroporation. Biomaterials (2012) 0.81
The transcription factor ATF2 promotes melanoma metastasis by suppressing protein fucosylation. Sci Signal (2015) 0.80
Histone deacetylase inhibitors induce invasion of human melanoma cells in vitro via differential regulation of N-cadherin expression and RhoA activity. BMC Cancer (2016) 0.80
Glycosylation modulates melanoma cell α2β1 and α3β1 integrin interactions with type IV collagen. J Biol Chem (2014) 0.79
Activated leukocyte cell adhesion molecule expression and shedding in thyroid tumors. PLoS One (2011) 0.79
Constitutive gray hair in mice induced by melanocyte-specific deletion of c-Myc. Pigment Cell Melanoma Res (2012) 0.78
Parallel damage in mitochondrial and lysosomal compartments promotes efficient cell death with autophagy: The case of the pentacyclic triterpenoids. Sci Rep (2015) 0.78
Sequential molecular analysis of circulating MCAM/MUC18 expression: a promising disease biomarker related to clinical outcome in melanoma. Arch Dermatol Res (2014) 0.78
AHNAK is downregulated in melanoma, predicts poor outcome, and may be required for the expression of functional cadherin-1. Melanoma Res (2016) 0.76
The effect of bacteriophages T4 and HAP1 on in vitro melanoma migration. BMC Microbiol (2009) 0.76
Narrow-band UVB radiation promotes dendrite formation by activating Rac1 in B16 melanoma cells. Mol Clin Oncol (2013) 0.76
Pagetoid melanocytes in nevi simulant of melanoma. Virchows Arch (2007) 0.75
RGDechi-hCit: αvβ3 selective pro-apoptotic peptide as potential carrier for drug delivery into melanoma metastatic cells. PLoS One (2014) 0.75
Prognostic significance of ALCAM (CD166/MEMD) expression in cutaneous melanoma patients. Diagn Pathol (2015) 0.75
Extracellular matrix-specific Caveolin-1 phosphorylation on tyrosine 14 is linked to augmented melanoma metastasis but not tumorigenesis. Oncotarget (2016) 0.75
Extracellular Matrix and Integrins in Embryonic Stem Cell Differentiation. Biochem Insights (2015) 0.75
Metastatic risk and resistance to BRAF inhibitors in melanoma defined by selective allelic loss of ATG5. Autophagy (2016) 0.75
Extracellular protonation modulates cell-cell interaction mechanics and tissue invasion in human melanoma cells. Sci Rep (2017) 0.75
Thrombomodulin modulates cell migration in human melanoma cell lines. Melanoma Res (2014) 0.75
Minimal residual disease in melanoma: circulating melanoma cells and predictive role of MCAM/MUC18/MelCAM/CD146. Cell Death Discov (2017) 0.75
Emerging Non-Canonical Functions and Regulation by p53: p53 and Stemness. Int J Mol Sci (2016) 0.75
Expression and distribution of MUC18 in human uveal melanoma. Virchows Arch (2007) 0.75
Antimetastatic activity and low systemic toxicity of tetradecyl gallate in a preclinical melanoma mouse model. Invest New Drugs (2011) 0.75
Mechanochemical feedback underlies coexistence of qualitatively distinct cell polarity patterns within diverse cell populations. Proc Natl Acad Sci U S A (2017) 0.75
MicroRNAs modulate hematopoietic lineage differentiation. Science (2003) 30.05
A global double-fluorescent Cre reporter mouse. Genesis (2007) 17.86
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proc Natl Acad Sci U S A (2008) 17.41
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature (2005) 14.65
High-throughput oncogene mutation profiling in human cancer. Nat Genet (2007) 12.68
Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K. Cancer Cell (2010) 12.50
BRAF and RAS mutations in human lung cancer and melanoma. Cancer Res (2002) 8.55
A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res (2005) 7.86
A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth. Cell (2010) 6.47
A promoter-level mammalian expression atlas. Nature (2014) 6.25
Modeling genomic diversity and tumor dependency in malignant melanoma. Cancer Res (2008) 5.95
Rheb promotes cell growth as a component of the insulin/TOR signalling network. Nat Cell Biol (2003) 5.01
Drosophila's insulin/PI3-kinase pathway coordinates cellular metabolism with nutritional conditions. Dev Cell (2002) 4.85
PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression. Cancer Res (2011) 4.80
Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. Genes Dev (2003) 4.68
Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases. Mol Cancer Ther (2006) 4.57
A new HPV-DNA test for cervical-cancer screening in developing regions: a cross-sectional study of clinical accuracy in rural China. Lancet Oncol (2008) 4.43
Suppression of BRAF(V599E) in human melanoma abrogates transformation. Cancer Res (2003) 4.28
Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885. Cancer Res (2006) 4.20
Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation. Cancer Res (2003) 4.03
Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development. Nat Cell Biol (2005) 3.80
MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells. PLoS One (2009) 3.66
Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt. Cancer Res (2004) 3.62
Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis. Mol Cell Biol (2003) 3.51
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature. Pigment Cell Res (2006) 3.42
Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart. J Biol Chem (2002) 3.22
Histone methylation by PRC2 is inhibited by active chromatin marks. Mol Cell (2011) 3.14
Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia. Hum Mol Genet (2008) 3.14
Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation. Proc Natl Acad Sci U S A (2012) 3.03
Axis of evil: molecular mechanisms of cancer metastasis. Oncogene (2003) 2.81
Role of toll-like receptor signalling in Abeta uptake and clearance. Brain (2006) 2.70
A randomized controlled trial of Licartin for preventing hepatoma recurrence after liver transplantation. Hepatology (2007) 2.66
The mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor AZD6244 (ARRY-142886) induces growth arrest in melanoma cells and tumor regression when combined with docetaxel. Clin Cancer Res (2008) 2.64
Effectiveness of bevacizumab with first-line combination chemotherapy for Medicare patients with stage IV colorectal cancer. J Clin Oncol (2012) 2.59
Epidermal growth factor receptor mediates increased cell proliferation, migration, and aggregation in esophageal keratinocytes in vitro and in vivo. J Biol Chem (2002) 2.58
The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth. Genes Dev (2007) 2.57
Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells. Cancer Cell (2013) 2.43
Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression. J Clin Invest (2005) 2.38
PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury. J Clin Invest (2005) 2.36
Life isn't flat: taking cancer biology to the next dimension. In Vitro Cell Dev Biol Anim (2006) 2.32
Spinal stenosis prevalence and association with symptoms: the Framingham Study. Spine J (2009) 2.32
The HSP90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanisms. Clin Cancer Res (2012) 2.31
Role of SCN5A Y1102 polymorphism in sudden cardiac death in blacks. Circulation (2005) 2.25
Prospective molecular profiling of melanoma metastases suggests classifiers of immune responsiveness. Cancer Res (2002) 2.21
Isolation of a novel population of multipotent adult stem cells from human hair follicles. Am J Pathol (2006) 2.13
Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression. Cancer Res (2006) 2.12
The influences of hyperprolactinemia and obesity on cardiovascular risk markers: effects of cabergoline therapy. Clin Endocrinol (Oxf) (2006) 2.09
Hepatic suppression of Foxo1 and Foxo3 causes hypoglycemia and hyperlipidemia in mice. Endocrinology (2011) 2.07
Rewired ERK-JNK signaling pathways in melanoma. Cancer Cell (2007) 2.03
PLX4032, a potent inhibitor of the B-Raf V600E oncogene, selectively inhibits V600E-positive melanomas. Pigment Cell Melanoma Res (2010) 2.02
The RAS/RAF/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma. Front Biosci (2005) 2.00
Intake of sucrose-sweetened water induces insulin resistance and exacerbates memory deficits and amyloidosis in a transgenic mouse model of Alzheimer disease. J Biol Chem (2007) 1.98
Institutional prescreening for detection and eradication of methicillin-resistant Staphylococcus aureus in patients undergoing elective orthopaedic surgery. J Bone Joint Surg Am (2010) 1.92
Myostatin regulates cardiomyocyte growth through modulation of Akt signaling. Circ Res (2006) 1.92
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells. Science (2015) 1.91
Shikonin circumvents cancer drug resistance by induction of a necroptotic death. Mol Cancer Ther (2007) 1.90
Up-regulated expression of zonula occludens protein-1 in human melanoma associates with N-cadherin and contributes to invasion and adhesion. Am J Pathol (2005) 1.88
Increased cyclin D1 expression can mediate BRAF inhibitor resistance in BRAF V600E-mutated melanomas. Mol Cancer Ther (2008) 1.86
Application of a BRAF pyrosequencing assay for mutation detection and copy number analysis in malignant melanoma. J Mol Diagn (2007) 1.85
Evidence for the formation of a novel nitrosothiol from the gaseous mediators nitric oxide and hydrogen sulphide. Biochem Biophys Res Commun (2006) 1.82
Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma. J Clin Invest (2014) 1.81
An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells. Cancer Res (2007) 1.81
Prospective study of iliac crest bone graft harvest site pain and morbidity. Spine J (2009) 1.80
Fibrinogen is required for maintenance of platelet intracellular and cell-surface P-selectin expression. Blood (2009) 1.79
Cyclin D1 is a candidate oncogene in cutaneous melanoma. Cancer Res (2002) 1.78
Paradoxical oncogenesis--the long-term effects of BRAF inhibition in melanoma. Nat Rev Clin Oncol (2013) 1.77
ICP27 recruits Aly/REF but not TAP/NXF1 to herpes simplex virus type 1 transcription sites although TAP/NXF1 is required for ICP27 export. J Virol (2005) 1.77
Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase. Cancer Cell (2010) 1.76
Obesity induces signs of premature cardiac aging in younger patients: the role of mitochondria. J Am Coll Cardiol (2011) 1.76
Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence. Cell Rep (2013) 1.74
Development and characterization of polymorphic microsatellite markers in Cyclobalanopsis glauca (Fagaceae). Am J Bot (2012) 1.72
The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxid Redox Signal (2010) 1.72
Spondylolysis and spondylolisthesis: prevalence and association with low back pain in the adult community-based population. Spine (Phila Pa 1976) (2009) 1.71
Detecting and targeting mesenchymal-like subpopulations within squamous cell carcinomas. Cell Cycle (2011) 1.70
A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification. J Clin Invest (2008) 1.69
The VPS33B-binding protein VPS16B is required in megakaryocyte and platelet α-granule biogenesis. Blood (2012) 1.67
Tumors as elusive targets of T-cell-based active immunotherapy. Trends Immunol (2003) 1.67
Platelet-associated complement factor H in healthy persons and patients with atypical HUS. Blood (2009) 1.67
Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease. J Neuroinflammation (2008) 1.67
Association between degenerative spondylolisthesis and spinous process fracture after interspinous process spacer surgery. Spine J (2012) 1.66
Transcriptional effects of chronic Akt activation in the heart. J Biol Chem (2002) 1.65
Facet joint osteoarthritis and low back pain in the community-based population. Spine (Phila Pa 1976) (2008) 1.64
PE, a new sulfated saponin from sea cucumber, exhibits anti-angiogenic and anti-tumor activities in vitro and in vivo. Cancer Biol Ther (2005) 1.64
Abnormal megakaryocyte development and platelet function in Nbeal2(-/-) mice. Blood (2013) 1.64
Pervasive nanoscale deformation twinning as a catalyst for efficient energy dissipation in a bioceramic armour. Nat Mater (2014) 1.62
Differential response of primary and metastatic melanomas to neutrophils attracted by IL-8. Int J Cancer (2003) 1.62
Mild traumatic brain injury among a cohort of rugby union players: predictors of time to injury. Br J Sports Med (2011) 1.60
Hydrogen sulphide: a novel endogenous gasotransmitter facilitates erectile function. J Sex Med (2007) 1.59
Acquired and intrinsic BRAF inhibitor resistance in BRAF V600E mutant melanoma. Biochem Pharmacol (2011) 1.59