Published in N Engl J Med on May 24, 2005
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med (2009) 7.17
Cluster analysis and clinical asthma phenotypes. Am J Respir Crit Care Med (2008) 5.80
An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications. Am J Respir Crit Care Med (2011) 5.53
Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: a randomised controlled trial. Lancet (2008) 4.06
Exhaled nitric oxide measurements: clinical application and interpretation. Thorax (2006) 2.01
Reports of clinical trials should begin and end with up-to-date systematic reviews of other relevant evidence: a status report. J R Soc Med (2007) 1.95
The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trial. J Allergy Clin Immunol (2007) 1.87
Acute exacerbations of asthma: epidemiology, biology and the exacerbation-prone phenotype. Clin Exp Allergy (2009) 1.87
Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjects. J Allergy Clin Immunol (2013) 1.80
International consensus on (ICON) pediatric asthma. Allergy (2012) 1.79
Asthma in the elderly: Current understanding and future research needs--a report of a National Institute on Aging (NIA) workshop. J Allergy Clin Immunol (2011) 1.69
Use of exhaled nitric oxide measurement to identify a reactive, at-risk phenotype among patients with asthma. Am J Respir Crit Care Med (2010) 1.68
Exhaled nitric oxide in the diagnosis and management of asthma: clinical implications. Chron Respir Dis (2009) 1.54
Can asthma control be improved by understanding the patient's perspective? BMC Pulm Med (2007) 1.51
Management of asthma in adults. CMAJ (2009) 1.43
Sputum proteomics in inflammatory and suppurative respiratory diseases. Am J Respir Crit Care Med (2008) 1.40
Alterations of the arginine metabolome in asthma. Am J Respir Crit Care Med (2008) 1.40
Human asthma phenotypes: from the clinic, to cytokines, and back again. Immunol Rev (2011) 1.29
Diagnosis and management of eosinophilic asthma: a US perspective. J Asthma Allergy (2014) 1.29
Increased oxidative stress in asymptomatic current chronic smokers and GOLD stage 0 COPD. Respir Res (2006) 1.17
Asthma exacerbations . 4: Prevention. Thorax (2006) 1.17
Noninvasive markers of airway inflammation in asthma. Clin Transl Sci (2009) 1.15
Performance of a new hand-held device for exhaled nitric oxide measurement in adults and children. Respir Res (2006) 1.13
Fractional exhaled nitric oxide measurements are most closely associated with allergic sensitization in school-age children. J Allergy Clin Immunol (2009) 1.11
Cardiovascular biomarkers in exhaled breath. Prog Cardiovasc Dis (2012) 1.09
Levels of nitric oxide oxidation products are increased in the epithelial lining fluid of children with persistent asthma. J Allergy Clin Immunol (2009) 1.08
Persistence of oxidant and protease burden in the airways after smoking cessation. BMC Pulm Med (2009) 1.06
Factors affecting exhaled nitric oxide measurements: the effect of sex. Respir Res (2007) 1.05
Longitudinal monitoring of lung injury in children after acute chlorine exposure in a swimming pool. Am J Respir Crit Care Med (2006) 1.05
Urinary bromotyrosine measures asthma control and predicts asthma exacerbations in children. J Pediatr (2011) 1.05
Measurement of IL-13-induced iNOS-derived gas phase nitric oxide in human bronchial epithelial cells. Am J Respir Cell Mol Biol (2007) 1.05
Airway inflammation in chronic obstructive pulmonary disease. J Thorac Dis (2014) 1.01
The inhaled phosphodiesterase 4 inhibitor GSK256066 reduces allergen challenge responses in asthma. Respir Res (2010) 1.01
Airway biomarkers of the oxidant burden in asthma and chronic obstructive pulmonary disease: current and future perspectives. Int J Chron Obstruct Pulmon Dis (2008) 1.00
Seasonal variation and environmental predictors of exhaled nitric oxide in children with asthma. Pediatr Pulmonol (2008) 0.99
Clinical patterns in asthma based on proximal and distal airway nitric oxide categories. Respir Res (2010) 0.97
Complexity of chronic asthma and chronic obstructive pulmonary disease: implications for risk assessment, and disease progression and control. Lancet (2008) 0.96
Effect of elevated exhaled nitric oxide levels on the risk of respiratory tract illness in preschool-aged children with moderate-to-severe intermittent wheezing. Ann Allergy Asthma Immunol (2009) 0.96
Epigenetic silencing of the human NOS2 gene: rethinking the role of nitric oxide in human macrophage inflammatory responses. J Immunol (2014) 0.96
Biomarkers in exhaled breath condensate: a review of collection, processing and analysis. J Breath Res (2008) 0.95
Impact of asthma on self-reported health status and quality of life: a population based study of Australians aged 18-64. Thorax (2005) 0.95
Measurement of tumor necrosis factor-alpha, leukotriene B4, and interleukin 8 in the exhaled breath condensate in patients with acute exacerbations of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis (2009) 0.93
Partitioned exhaled nitric oxide to non-invasively assess asthma. Respir Physiol Neurobiol (2008) 0.93
Open access integrated therapeutic and diagnostic platforms for personalized cardiovascular medicine. J Pers Med (2013) 0.91
Electronic nose breathprints are independent of acute changes in airway caliber in asthma. Sensors (Basel) (2010) 0.88
IgE sensitisation in relation to flow-independent nitric oxide exchange parameters. Respir Res (2006) 0.88
Atopic sensitization to common allergens without symptoms or signs of airway disorders does not increase exhaled nitric oxide. Clin Respir J (2008) 0.88
Asthma and obesity: does weight loss improve asthma control? a systematic review. J Asthma Allergy (2012) 0.87
Airways disease: phenotyping heterogeneity using measures of airway inflammation. Allergy Asthma Clin Immunol (2007) 0.87
Elevation in exhaled nitric oxide predicts for radiation pneumonitis. Int J Radiat Oncol Biol Phys (2011) 0.86
Assessment of fractionated exhaled nitric oxide as a biomarker for the treatment of eosinophilic esophagitis. Allergy Asthma Proc (2013) 0.86
Exhaled carbon monoxide in asthmatics: a meta-analysis. Respir Res (2010) 0.85
Exhaled nitric oxide in asthma: progress since the introduction of standardized methodology. J Breath Res (2008) 0.85
Pharmacologic inhibition of S-nitrosoglutathione reductase protects against experimental asthma in BALB/c mice through attenuation of both bronchoconstriction and inflammation. BMC Pulm Med (2014) 0.84
Asthma control in adults. BMJ (2006) 0.84
Cost analysis of monitoring asthma treatment using sputum cell counts. Can Respir J (2008) 0.83
Effect of nanoparticles exposure on fractional exhaled nitric oxide (FENO) in workers exposed to nanomaterials. Int J Mol Sci (2014) 0.83
Fractional exhaled nitric oxide for the management of asthma in adults: a systematic review. Eur Respir J (2016) 0.82
Fractional exhaled nitric oxide and forced expiratory flow between 25% and 75% of vital capacity in children with controlled asthma. Korean J Pediatr (2012) 0.82
Clinical use of exhaled biomarkers in COPD. Int J Chron Obstruct Pulmon Dis (2007) 0.82
Approaches to stepping up and stepping down care in asthmatic patients. J Allergy Clin Immunol (2011) 0.82
Role of inducible nitric oxide synthase on the development of virus-associated asthma exacerbation which is dependent on Th1 and Th17 cell responses. Exp Mol Med (2010) 0.82
Prevalence of asthma symptoms based on the European Community Respiratory Health Survey questionnaire and FENO in university students: gender differences in symptoms and FENO. Allergy Asthma Clin Immunol (2011) 0.81
Update on clinical inflammometry for the management of airway diseases. Can Respir J (2013) 0.81
Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants. J Allergy Clin Immunol (2013) 0.81
The effectiveness of non-pharmacological healthcare interventions for asthma management during pregnancy: a systematic review. BMC Pulm Med (2014) 0.80
Biomarkers in asthma: a real hope to better manage asthma. Clin Chest Med (2012) 0.80
FeNO as a Marker of Airways Inflammation: The Possible Implications in Childhood Asthma Management. J Allergy (Cairo) (2010) 0.80
Asthma control cost-utility randomized trial evaluation (ACCURATE): the goals of asthma treatment. BMC Pulm Med (2011) 0.79
Inhaled Corticosteroids. Pharmaceuticals (Basel) (2010) 0.79
Urinary leukotriene E₄ levels identify children with tobacco smoke exposure at risk for asthma exacerbation. J Allergy Clin Immunol (2011) 0.79
Effects of extra-fine inhaled and oral corticosteroids on alveolar nitric oxide in COPD. Lung (2012) 0.79
Pharmacotherapy of patients with mild persistent asthma: strategies and unresolved issues. Front Pharmacol (2011) 0.79
Biomarkers in airway diseases. Can Respir J (2013) 0.79
Multiple flow rates measurement of exhaled nitric oxide in patients with sarcoidosis: a pilot feasibility study. Sarcoidosis Vasc Diffuse Lung Dis (2009) 0.79
MyAirCoach: the use of home-monitoring and mHealth systems to predict deterioration in asthma control and the occurrence of asthma exacerbations; study protocol of an observational study. BMJ Open (2017) 0.79
The effects of age on exhaled breath nitric oxide levels. Lung (2006) 0.78
Exhaled nitric oxide predicts eosinophilic airway inflammation in COPD. Lung (2014) 0.78
Measurements of fractional exhaled nitric oxide in pediatric asthma. Korean J Pediatr (2013) 0.78
Stepping down asthma treatment: how and when. Curr Opin Pulm Med (2012) 0.78
A sensitive high throughput ELISA for human eosinophil peroxidase: a specific assay to quantify eosinophil degranulation from patient-derived sources. J Immunol Methods (2012) 0.78
Exhaled nitric oxide in stable chronic obstructive pulmonary disease. Ann Thorac Med (2009) 0.78
Using fractional exhaled nitric oxide (FeNO) to diagnose steroid-responsive disease and guide asthma management in routine care. Clin Transl Allergy (2013) 0.78
Diagnostic approach in cases with suspected work-related asthma. J Occup Med Toxicol (2013) 0.78
Longitudinal measurement of airway inflammation over one year in children and adults with intermittent asthma. BMC Res Notes (2014) 0.78
Alveolar nitric oxide and its role in pediatric asthma control assessment. BMC Pulm Med (2014) 0.77
FeNO and asthma treatment in children: a systematic review and meta-analysis. Medicine (Baltimore) (2015) 0.77
Study of the correlations between fractional exhaled nitric oxide in exhaled breath and atopic status, blood eosinophils, FCER2 mutation, and asthma control in Vietnamese children. J Asthma Allergy (2016) 0.77
Exhaled Nitric Oxide Levels Among Adults With Excessive Alcohol Consumption. Chest (2016) 0.77
The effect of the novel phosphodiesterase-4 inhibitor MEM 1414 on the allergen induced responses in mild asthma. BMC Pulm Med (2014) 0.76
Online sample conditioning for portable breath analyzers. Anal Chem (2012) 0.76
Nitric oxide measurement in chronic cough. Lung (2009) 0.76
New Insights in Oxidant Biology in Asthma. Ann Am Thorac Soc (2016) 0.76
Exhaled nitric oxide and asthma. N Engl J Med (2005) 0.76
The clinical significance of exhaled nitric oxide in asthma. Can Respir J (2008) 0.76
Application of Cavity Enhanced Absorption Spectroscopy to the Detection of Nitric Oxide, Carbonyl Sulphide, and Ethane--Breath Biomarkers of Serious Diseases. Sensors (Basel) (2015) 0.76
Effect of fluticasone 250 microg/salmeterol 50 microg and montelukast on exhaled nitric oxide in asthmatic patients. Can Respir J (2008) 0.76
An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am J Respir Crit Care Med (2009) 9.38
A longitudinal, population-based, cohort study of childhood asthma followed to adulthood. N Engl J Med (2003) 7.03
An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications. Am J Respir Crit Care Med (2011) 5.53
Long-term relation between breastfeeding and development of atopy and asthma in children and young adults: a longitudinal study. Lancet (2002) 4.89
Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: a double-blind, randomised controlled trial. Lancet (2011) 3.21
Effects of steroid therapy on inflammatory cell subtypes in asthma. Thorax (2009) 2.82
Risk factors for airway remodeling in asthma manifested by a low postbronchodilator FEV1/vital capacity ratio: a longitudinal population study from childhood to adulthood. Am J Respir Crit Care Med (2002) 2.33
Exhaled nitric oxide in pulmonary diseases: a comprehensive review. Chest (2010) 2.29
Cats and dogs and the risk of atopy in childhood and adulthood. J Allergy Clin Immunol (2009) 2.25
Pelvic floor muscle training for prevention and treatment of urinary and faecal incontinence in antenatal and postnatal women. Cochrane Database Syst Rev (2008) 1.96
The association between obesity and asthma: interactions between systemic and airway inflammation. Am J Respir Crit Care Med (2008) 1.78
Sex differences in the relation between body mass index and asthma and atopy in a birth cohort. Am J Respir Crit Care Med (2004) 1.76
Diagnosing asthma: comparisons between exhaled nitric oxide measurements and conventional tests. Am J Respir Crit Care Med (2003) 1.74
Postoperative anemia and quality of life after primary hip arthroplasty in patients over 65 years old. Anesth Analg (2008) 1.68
Psychotropic drugs and fatal pulmonary embolism. Pharmacoepidemiol Drug Saf (2003) 1.66
Accuracy of monitoring for sleep-related breathing disorders in the coronary care unit. Chest (2005) 1.63
Predicting corticosteroid response in chronic obstructive pulmonary disease using exhaled nitric oxide. Am J Respir Crit Care Med (2009) 1.60
Exhaled nitric oxide: a predictor of steroid response. Am J Respir Crit Care Med (2005) 1.50
Asthma phenotypes: consistency of classification using induced sputum. Respirology (2012) 1.50
Feedback or biofeedback to augment pelvic floor muscle training for urinary incontinence in women. Cochrane Database Syst Rev (2011) 1.49
Adverse effects of short-acting beta-agonists: potential impact when anti-inflammatory therapy is inadequate. Respirology (2004) 1.49
Feedback or biofeedback to augment pelvic floor muscle training for urinary incontinence in women: shortened version of a Cochrane systematic review. Neurourol Urodyn (2012) 1.47
Associations between fluctuations in lung function and asthma control in two populations with differing asthma severity. Thorax (2011) 1.39
A survey of respiratory and sleep services in New Zealand undertaken by the Thoracic Society of Australia and New Zealand (TSANZ). N Z Med J (2009) 1.38
Risk of severe asthma episodes predicted from fluctuation analysis of airway function. Nature (2005) 1.36
Risk factors for hospital admission for asthma from childhood to young adulthood: a longitudinal population study. J Allergy Clin Immunol (2002) 1.31
Sex differences in factors associated with childhood- and adolescent-onset wheeze. Am J Respir Crit Care Med (2005) 1.26
Systemic inflammation and lung function in young adults. Thorax (2007) 1.23
Adiposity, asthma, and airway inflammation. J Allergy Clin Immunol (2006) 1.22
Cigarette smoking and allergic sensitization: a 32-year population-based cohort study. J Allergy Clin Immunol (2007) 1.15
Interventions for protecting renal function in the perioperative period. Cochrane Database Syst Rev (2008) 1.10
Dynamic hyperinflation with bronchoconstriction: differences between obese and nonobese women with asthma. Am J Respir Crit Care Med (2008) 1.09
Botulinum toxin injections for adults with overactive bladder syndrome. Cochrane Database Syst Rev (2011) 1.09
Associations between respiratory symptoms, lung function and gastro-oesophageal reflux symptoms in a population-based birth cohort. Respir Res (2006) 1.09
Simvastatin in the treatment of asthma: lack of steroid-sparing effect. Thorax (2010) 1.09
Load-deflection characteristics of superelastic nickel-titanium orthodontic wires. Am J Orthod Dentofacial Orthop (2002) 1.09
Which anticholinergic drug for overactive bladder symptoms in adults. Cochrane Database Syst Rev (2012) 1.08
Efficacy of the 'tennis ball technique' versus nCPAP in the management of position-dependent obstructive sleep apnoea syndrome. Respirology (2008) 1.06
Comparisons of approaches to pelvic floor muscle training for urinary incontinence in women. Cochrane Database Syst Rev (2011) 1.06
Factors affecting exhaled nitric oxide measurements: the effect of sex. Respir Res (2007) 1.05
Recovery after injury: an individual patient data meta-analysis of general health status using the EQ-5D. J Trauma (2011) 1.03
Is exhaled nitric oxide measurement a useful clinical test in asthma? Curr Opin Allergy Clin Immunol (2005) 1.00
Persistent urinary incontinence and delivery mode history: a six-year longitudinal study. BJOG (2006) 1.00
Preoperative carbohydrate treatment for enhancing recovery after elective surgery. Cochrane Database Syst Rev (2014) 0.97
Bronchodilator response in relation to beta2-adrenoceptor haplotype in patients with asthma. Am J Respir Crit Care Med (2005) 0.96
Breastfeeding and asthma: appraising the controversy--a rebuttal. Pediatr Pulmonol (2003) 0.95
Exhaled NO and exhaled breath condensate pH in the evaluation of asthma control. Respir Med (2010) 0.94
Return to continence after radical retropubic prostatectomy: a randomized trial of verbal and written instructions versus therapist-directed pelvic floor muscle therapy. Urology (2008) 0.94
Exhaled nitric oxide levels in asthma: Personal best versus reference values. J Allergy Clin Immunol (2009) 0.92
Interventions for protecting renal function in the perioperative period. Cochrane Database Syst Rev (2013) 0.92
The role of sleep-disordered breathing, daytime sleepiness, and impaired performance in motor vehicle crashes-a case control study. Sleep Breath (2004) 0.90
Outcome in adulthood of asymptomatic airway hyperresponsiveness in childhood: a longitudinal population study. Pediatr Pulmonol (2002) 0.89
Randomised controlled trial of conservative management of postnatal urinary and faecal incontinence: six year follow up. BMJ (2004) 0.89
A randomized crossover efficacy trial of oral CPAP (Oracle) compared with nasal CPAP in the management of obstructive sleep apnea. Sleep (2003) 0.88
Continuous positive airway pressure (CPAP) during the postoperative period for prevention of postoperative morbidity and mortality following major abdominal surgery. Cochrane Database Syst Rev (2014) 0.87
Lack of efficacy for a cervicomandibular support collar in the management of obstructive sleep apnea. Chest (2004) 0.87
Noise exposure and hearing loss in agriculture: a survey of farmers and farm workers in the Southland region of New Zealand. J Occup Environ Med (2003) 0.87
Inflammometry to assess airway diseases. Lancet (2008) 0.86
Outcome after injury-a systematic literature search of studies using the EQ-5D. J Trauma (2009) 0.86
Early detection of asthma exacerbations by using action points in self-management plans. Eur Respir J (2012) 0.85
The efficacy of a novel tongue-stabilizing device on polysomnographic variables in sleep-disordered breathing: a pilot study. Sleep Breath (2002) 0.85
Asthma in remission: can relapse in early adulthood be predicted at 18 years of age? Chest (2005) 0.84
Adherence to asthma self-management plans with inhaled corticosteroid and oral prednisone: A descriptive analysis. Respirology (2002) 0.84
Air travel and fatal pulmonary embolism. Thromb Haemost (2006) 0.84
Fractional exhaled nitric oxide in asthma: an update. Respirology (2009) 0.84
Elevated posture for the management of obstructive sleep apnea. Sleep Breath (2004) 0.82
Effect of caffeine ingestion on exhaled nitric oxide measurements in patients with asthma. Am J Respir Crit Care Med (2004) 0.82