Published in Diabetes on June 01, 2005
C/EBPalpha and the corepressors CtBP1 and CtBP2 regulate repression of select visceral white adipose genes during induction of the brown phenotype in white adipocytes by peroxisome proliferator-activated receptor gamma agonists. Mol Cell Biol (2009) 1.98
Physiological, pharmacological, and nutritional regulation of circulating adiponectin concentrations in humans. Metab Syndr Relat Disord (2008) 1.95
Genome-wide profiling of H3K56 acetylation and transcription factor binding sites in human adipocytes. PLoS One (2011) 1.34
Adiponectin reduces plasma triglyceride by increasing VLDL triglyceride catabolism. Diabetes (2008) 1.28
Functional characterization of promoter variants of the adiponectin gene complemented by epidemiological data. Diabetes (2008) 1.15
Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue. PLoS One (2011) 1.13
Mechanisms of chronic state of inflammation as mediators that link obese adipose tissue and metabolic syndrome. Mediators Inflamm (2013) 1.11
Adiponectin inhibits lipolysis in mouse adipocytes. Diabetes (2011) 1.10
A novel selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis. J Endocrinol (2008) 1.06
Population-specific coding variant underlies genome-wide association with adiponectin level. Hum Mol Genet (2011) 1.04
Adiponectin increases skeletal muscle mitochondrial biogenesis by suppressing mitogen-activated protein kinase phosphatase-1. Diabetes (2012) 0.99
Energy intake and adiponectin gene expression. Am J Physiol Endocrinol Metab (2011) 0.97
Distinct regulatory mechanisms governing embryonic versus adult adipocyte maturation. Nat Cell Biol (2015) 0.96
12/15-Lipoxygenase signaling in the endoplasmic reticulum stress response. Am J Physiol Endocrinol Metab (2012) 0.95
Peroxisome proliferator-activated receptor γ and C/EBPα synergistically activate key metabolic adipocyte genes by assisted loading. Mol Cell Biol (2013) 0.94
Hzf regulates adipogenesis through translational control of C/EBPalpha. EMBO J (2008) 0.94
An insertion/deletion polymorphism of the dihydrofolate reductase (DHFR) gene is associated with serum and red blood cell folate concentrations in women. Hum Genet (2008) 0.93
Analysis of intron sequence features associated with transcriptional regulation in human genes. PLoS One (2012) 0.93
Mechanisms regulating repression of haptoglobin production by peroxisome proliferator-activated receptor-gamma ligands in adipocytes. Endocrinology (2009) 0.93
A novel association of a polymorphism in the first intron of adiponectin gene with type 2 diabetes, obesity and hypoadiponectinemia in Asian Indians. Hum Genet (2008) 0.90
Hypoadiponectinaemia in diabetes mellitus type 2: molecular mechanisms and clinical significance. Clin Exp Pharmacol Physiol (2011) 0.89
Common variants in adiponectin gene are associated with coronary artery disease and angiographical severity of coronary atherosclerosis in type 2 diabetes. Cardiovasc Diabetol (2013) 0.88
A single nucleotide polymorphism in ADIPOQ predicts biochemical recurrence after radical prostatectomy in localized prostate cancer. Oncotarget (2015) 0.85
Transcriptional regulation of fatty acid translocase/CD36 expression by CCAAT/enhancer-binding protein alpha. J Biol Chem (2008) 0.84
The mixed-lineage kinase DLK is a key regulator of 3T3-L1 adipocyte differentiation. PLoS One (2009) 0.83
B56alpha/protein phosphatase 2A inhibits adipose lipolysis in high-fat diet-induced obese mice. Endocrinology (2010) 0.83
The modulation of adiponectin by STAT5-activating hormones. Am J Physiol Endocrinol Metab (2015) 0.80
Ultraviolet B irradiation reduces the expression of adiponectin in ovarial adipose tissues through endocrine actions of calcitonin gene-related peptide-induced serum amyloid A. PLoS One (2014) 0.79
The aporphine alkaloid boldine induces adiponectin expression and regulation in 3T3-L1 cells. J Med Food (2009) 0.79
Genetic variants in adiponectin and blood pressure responses to dietary sodium or potassium interventions: a family-based association study. J Hum Hypertens (2016) 0.78
UV-induced inhibition of adipokine production in subcutaneous fat aggravates dermal matrix degradation in human skin. Sci Rep (2016) 0.77
Knockout maternal adiponectin increases fetal growth in mice: potential role for trophoblast IGFBP-1. Diabetologia (2016) 0.77
Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease. Mol Metab (2016) 0.77
Association of ADIPOQ variants with type 2 diabetes mellitus susceptibility in ethnic Han Chinese from northeast China. J Diabetes Investig (2016) 0.76
Inside out: Bone marrow adipose tissue as a source of circulating adiponectin. Adipocyte (2016) 0.76
PI3K-resistant GSK3 controls adiponectin formation and protects from metabolic syndrome. Proc Natl Acad Sci U S A (2016) 0.76
Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function. Nutr Metab (Lond) (2011) 0.76
Genetic polymorphisms of the main transcription factors for adiponectin gene promoter in regulation of adiponectin levels: association analysis in three European cohorts. PLoS One (2012) 0.75
Role of Protein Phosphatase 2A in Osteoblast Differentiation and Function. J Clin Med (2017) 0.75
Adiponectin, Retinoic Acid Receptor Responder 2, and Peroxisome Proliferator-Activated Receptor-γ Coativator-1 Genes and the Risk for Obesity. Dis Markers (2017) 0.75
Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primates. J Clin Invest (2009) 3.10
SIRT1 regulates adiponectin gene expression through Foxo1-C/enhancer-binding protein alpha transcriptional complex. J Biol Chem (2006) 2.42
Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome. Nat Commun (2013) 2.29
Maternal obesity and fetal metabolic programming: a fertile epigenetic soil. Am J Physiol Regul Integr Comp Physiol (2010) 2.28
TNF-alpha is a predictor of insulin resistance in human pregnancy. Diabetes (2002) 2.20
Hepatitis C virus infection: molecular pathways to metabolic syndrome. Hepatology (2008) 2.10
An anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamics. EMBO J (2006) 1.99
Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation. Biochem J (2011) 1.96
CD44v6 dependence of premetastatic niche preparation by exosomes. Neoplasia (2009) 1.80
Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice. Proc Natl Acad Sci U S A (2012) 1.72
Cellular mechanisms for insulin resistance in normal pregnancy and gestational diabetes. Diabetes Care (2007) 1.70
High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase. Hepatology (2013) 1.56
CCAAT/enhancing binding protein beta deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steatohepatitis. Hepatology (2007) 1.49
Skeletal muscle-specific deletion of lipoprotein lipase enhances insulin signaling in skeletal muscle but causes insulin resistance in liver and other tissues. Diabetes (2008) 1.41
Phosphoenolpyruvate carboxykinase overexpression selectively attenuates insulin signaling and hepatic insulin sensitivity in transgenic mice. J Biol Chem (2002) 1.38
Growth hormone regulation of p85alpha expression and phosphoinositide 3-kinase activity in adipose tissue: mechanism for growth hormone-mediated insulin resistance. Diabetes (2007) 1.36
Induced oxidative stress and activated expression of manganese superoxide dismutase during hepatitis C virus replication: role of JNK, p38 MAPK and AP-1. Biochem J (2004) 1.36
Downregulated IRS-1 and PPARgamma in obese women with gestational diabetes: relationship to FFA during pregnancy. Am J Physiol Endocrinol Metab (2002) 1.35
CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice. J Biol Chem (2007) 1.35
De novo generation of white adipocytes from the myeloid lineage via mesenchymal intermediates is age, adipose depot, and gender specific. Proc Natl Acad Sci U S A (2010) 1.35
Intrauterine growth restriction increases fetal hepatic gluconeogenic capacity and reduces messenger ribonucleic acid translation initiation and nutrient sensing in fetal liver and skeletal muscle. Endocrinology (2009) 1.32
Adiponectin reduces plasma triglyceride by increasing VLDL triglyceride catabolism. Diabetes (2008) 1.28
C/EBP transcription factors regulate SREBP1c gene expression during adipogenesis. Biochem J (2009) 1.28
Human placental growth hormone increases expression of the p85 regulatory unit of phosphatidylinositol 3-kinase and triggers severe insulin resistance in skeletal muscle. Endocrinology (2003) 1.26
Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease. J Lipid Res (2013) 1.25
Aldehyde dehydrogenase 1B1 (ALDH1B1) is a potential biomarker for human colon cancer. Biochem Biophys Res Commun (2011) 1.25
Patterns of glycemia in normal pregnancy: should the current therapeutic targets be challenged? Diabetes Care (2011) 1.24
Aldehyde dehydrogenase 1B1: molecular cloning and characterization of a novel mitochondrial acetaldehyde-metabolizing enzyme. Drug Metab Dispos (2010) 1.24
3D models of epithelial-mesenchymal transition in breast cancer metastasis: high-throughput screening assay development, validation, and pilot screen. J Biomol Screen (2011) 1.24
Chronic late-gestation hypoglycemia upregulates hepatic PEPCK associated with increased PGC1alpha mRNA and phosphorylated CREB in fetal sheep. Am J Physiol Endocrinol Metab (2007) 1.23
Increased P85alpha is a potent negative regulator of skeletal muscle insulin signaling and induces in vivo insulin resistance associated with growth hormone excess. J Biol Chem (2005) 1.22
Inflammatory biomarkers of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced skin injury in SKH-1 hairless mice. Toxicol Sci (2008) 1.22
Lipid droplet targeting domains of adipophilin. J Lipid Res (2003) 1.20
Reversal of insulin resistance postpartum is linked to enhanced skeletal muscle insulin signaling. J Clin Endocrinol Metab (2004) 1.15
Mammary glands of adipophilin-null mice produce an amino-terminally truncated form of adipophilin that mediates milk lipid droplet formation and secretion. J Lipid Res (2007) 1.15
Intrahepatic fat is increased in the neonatal offspring of obese women with gestational diabetes. J Pediatr (2012) 1.14
Role of adipocytokines in obesity-associated insulin resistance. J Nutr Biochem (2007) 1.14
Oxidative inactivation of mitochondrial aconitase results in iron and H2O2-mediated neurotoxicity in rat primary mesencephalic cultures. PLoS One (2009) 1.13
Maternal high fat diet is associated with decreased plasma n-3 fatty acids and fetal hepatic apoptosis in nonhuman primates. PLoS One (2011) 1.13
Tumor signaling to the bone marrow changes the phenotype of monocytes and pulmonary macrophages during urethane-induced primary lung tumorigenesis in A/J mice. Am J Pathol (2007) 1.13
A maternal high-fat diet modulates fetal SIRT1 histone and protein deacetylase activity in nonhuman primates. FASEB J (2012) 1.11
Human placental growth hormone causes severe insulin resistance in transgenic mice. Am J Obstet Gynecol (2002) 1.11
CCAAT/enhancer-binding protein alpha mediates induction of hepatic phosphoenolpyruvate carboxykinase by p38 mitogen-activated protein kinase. J Biol Chem (2006) 1.11
Adiponectin inhibits lipolysis in mouse adipocytes. Diabetes (2011) 1.10
Transduction of the mammary epithelium with adenovirus vectors in vivo. J Virol (2003) 1.09
knocking down liver ccaat/enhancer-binding protein alpha by adenovirus-transduced silent interfering ribonucleic acid improves hepatic gluconeogenesis and lipid homeostasis in db/db mice. Endocrinology (2006) 1.09
Molecular determinants of milk lipid secretion. J Mammary Gland Biol Neoplasia (2007) 1.08
Cytoplasmic lipid droplet accumulation in developing mammary epithelial cells: roles of adipophilin and lipid metabolism. J Lipid Res (2007) 1.08
CCAAT/enhancer-binding protein β (C/EBPβ) expression regulates dietary-induced inflammation in macrophages and adipose tissue in mice. J Biol Chem (2012) 1.07
Sequential regulation of diacylglycerol acyltransferase 2 expression by CAAT/enhancer-binding protein beta (C/EBPbeta) and C/EBPalpha during adipogenesis. J Biol Chem (2007) 1.06
Overexpression of human alpha-synuclein causes dopamine neuron death in primary human mesencephalic culture. Brain Res (2002) 1.06
Suppression of adiponectin gene expression by histone deacetylase inhibitor valproic acid. Endocrinology (2005) 1.03
A test of current models for the mechanism of milk-lipid droplet secretion. Traffic (2013) 1.03
Phosphatidylinositol 3-kinase redistribution is associated with skeletal muscle insulin resistance in gestational diabetes mellitus. Diabetes (2002) 1.02
Determinants of adipophilin function in milk lipid formation and secretion. Trends Endocrinol Metab (2011) 1.02
Interaction between FIP5 and SNX18 regulates epithelial lumen formation. J Cell Biol (2011) 1.02
Aldehyde dehydrogenase 3B1 (ALDH3B1): immunohistochemical tissue distribution and cellular-specific localization in normal and cancerous human tissues. J Histochem Cytochem (2010) 1.01
Experimental evidence for therapeutic potential of taurine in the treatment of nonalcoholic fatty liver disease. Am J Physiol Regul Integr Comp Physiol (2011) 1.01
Acute supplementation of amino acids increases net protein accretion in IUGR fetal sheep. Am J Physiol Endocrinol Metab (2012) 1.01
Chronic hyperglycemia enhances PEPCK gene expression and hepatocellular glucose production via elevated liver activating protein/liver inhibitory protein ratio. Diabetes (2005) 1.01
Efficient adenovirus transduction of 3T3-L1 adipocytes stably expressing coxsackie-adenovirus receptor. Biochem Biophys Res Commun (2003) 1.01
Transgenic increase in N-3/n-6 Fatty Acid ratio reduces maternal obesity-associated inflammation and limits adverse developmental programming in mice. PLoS One (2013) 1.01
Insulin is required for amino acid stimulation of dual pathways for translational control in skeletal muscle in the late-gestation ovine fetus. Am J Physiol Endocrinol Metab (2008) 1.00
Adiponectin increases skeletal muscle mitochondrial biogenesis by suppressing mitogen-activated protein kinase phosphatase-1. Diabetes (2012) 0.99
Reduced mitochondrial function in obesity-associated fatty liver: SIRT3 takes on the fat. Aging (Albany NY) (2011) 0.99
Dynamic regulation of hepatic lipid droplet properties by diet. PLoS One (2013) 0.98
Effect of spontaneous gestational diabetes on fetal and postnatal hepatic insulin resistance in Lepr(db/+) mice. Pediatr Res (2003) 0.98
Impact of high-fat diet and obesity on energy balance and fuel utilization during the metabolic challenge of lactation. Obesity (Silver Spring) (2011) 0.98
Oxidative Stress and the ER Stress Response in a Murine Model for Early-Stage Alcoholic Liver Disease. J Toxicol (2012) 0.97
Energy intake and adiponectin gene expression. Am J Physiol Endocrinol Metab (2011) 0.97
Regulation of cyclin D1 and Wnt10b gene expression by cAMP-responsive element-binding protein during early adipogenesis involves differential promoter methylation. J Biol Chem (2008) 0.97
Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells. Mol Endocrinol (2006) 0.97
Overexpression of peroxiredoxin 6 does not prevent ethanol-mediated oxidative stress and may play a role in hepatic lipid accumulation. J Pharmacol Exp Ther (2009) 0.97
Increased hepatic glucose production in fetal sheep with intrauterine growth restriction is not suppressed by insulin. Diabetes (2012) 0.96
Adiponectin and energy homeostasis. Rev Endocr Metab Disord (2014) 0.96
Adipophilin regulates maturation of cytoplasmic lipid droplets and alveolae in differentiating mammary glands. J Cell Sci (2011) 0.96
The adipophilin C terminus is a self-folding membrane-binding domain that is important for milk lipid secretion. J Biol Chem (2011) 0.94
2-Chloroethyl ethyl sulfide causes microvesication and inflammation-related histopathological changes in male hairless mouse skin. Toxicology (2011) 0.94
Prolactin, progesterone, and dexamethasone coordinately and adversely regulate glucokinase and cAMP/PDE cascades in MIN6 beta-cells. Am J Physiol Endocrinol Metab (2003) 0.94
Increased susceptibility of natural killer T-cell-deficient mice to acetaminophen-induced liver injury. Hepatology (2013) 0.94
Fenofibrate and PBA prevent fatty acid-induced loss of adiponectin receptor and pAMPK in human hepatoma cells and in hepatitis C virus-induced steatosis. J Lipid Res (2009) 0.93
Widespread phosphorylation of histone H2AX by species C adenovirus infection requires viral DNA replication. J Virol (2009) 0.93