Published in Aging Cell on June 01, 2005
Functional estrogen receptors in the mitochondria of breast cancer cells. Mol Biol Cell (2006) 1.72
Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal (2011) 1.57
Targeted functional imaging of estrogen receptors with 99mTc-GAP-EDL. Eur J Nucl Med Mol Imaging (2006) 1.53
Oestrogens ameliorate mitochondrial dysfunction in Leber's hereditary optic neuropathy. Brain (2010) 1.52
Protective effect of sex on chronic stress- and depressive behavior-induced vascular dysfunction in BALB/cJ mice. J Appl Physiol (1985) (2014) 1.45
Sex differences in age trajectories of physiological dysregulation: inflammation, metabolic syndrome, and allostatic load. J Gerontol A Biol Sci Med Sci (2011) 1.31
Mitochondrial mechanisms of estrogen neuroprotection. Biochim Biophys Acta (2009) 1.25
Postmenopausal hypertension. Am J Hypertens (2011) 1.22
Structure-nongenomic neuroprotection relationship of estrogens and estrogen-derived compounds. Pharmacol Ther (2007) 1.09
Sex differences in control of blood pressure: role of oxidative stress in hypertension in females. Am J Physiol Heart Circ Physiol (2008) 1.08
Estrogen receptor GPR30 reduces oxidative stress and proteinuria in the salt-sensitive female mRen2.Lewis rat. Hypertension (2011) 1.06
17β-Estradiol, aging, inflammation, and the stress response in the female heart. Endocrinology (2011) 0.99
Properties of Resveratrol: In Vitro and In Vivo Studies about Metabolism, Bioavailability, and Biological Effects in Animal Models and Humans. Oxid Med Cell Longev (2015) 0.97
Mitochondrial superoxide dismutase activation with 17 beta-estradiol-treated human lens epithelial cells. Mol Vis (2008) 0.94
Sex hormones modulate circulating antioxidant enzymes: impact of estrogen therapy. Redox Biol (2013) 0.94
Evaluation of sex differences on mitochondrial bioenergetics and apoptosis in mice. Exp Gerontol (2006) 0.91
Oestrogen-mediated cardioprotection following ischaemia and reperfusion is mimicked by an oestrogen receptor (ER)alpha agonist and unaffected by an ER beta antagonist. J Endocrinol (2008) 0.88
Rapid activation of nuclear factor κB by 17β-estradiol and selective estrogen receptor modulators: pathways mediating cellular protection. Shock (2012) 0.87
Phytoestrogens enhance antioxidant enzymes after swimming exercise and modulate sex hormone plasma levels in female swimmers. Eur J Appl Physiol (2011) 0.87
Role of uncoupling proteins in cancer. Cancers (Basel) (2010) 0.86
Mitochondrial and sex steroid hormone crosstalk during aging. Longev Healthspan (2014) 0.86
Early, but not late onset estrogen replacement therapy prevents oxidative stress and metabolic alterations caused by ovariectomy. Antioxid Redox Signal (2013) 0.83
Chemical structures of 4-oxo-flavonoids in relation to inhibition of oxidized low-density lipoprotein (LDL)-induced vascular endothelial dysfunction. Int J Mol Sci (2011) 0.83
Mitochondrial p38β and manganese superoxide dismutase interaction mediated by estrogen in cardiomyocytes. PLoS One (2014) 0.83
PTEN mediates the antioxidant effect of resveratrol at nutritionally relevant concentrations. Biomed Res Int (2014) 0.82
Neuroprotective effects of nonfeminizing estrogens in retinal photoreceptor neurons. Invest Ophthalmol Vis Sci (2012) 0.81
Effects of ovariectomy and resistance training on oxidative stress markers in the rat liver. Clinics (Sao Paulo) (2013) 0.80
Plasma membrane receptor mediated MAPK signaling pathways are activated in human uterine cervix at parturition. Reprod Biol Endocrinol (2007) 0.79
Effects of estrogen on hyperglycemia and liver dysfunction in diabetic male rats. Int J Physiol Pathophysiol Pharmacol (2012) 0.79
L-selenomethionine does not protect against testosterone plus 17β-estradiol-induced oxidative stress and preneoplastic lesions in the prostate of NBL rats. Nutr Cancer (2014) 0.77
Dynamics of enhanced mitochondrial respiration in female compared with male rat cerebral arteries. Am J Physiol Heart Circ Physiol (2015) 0.77
Efficacy of female rat models in translational cardiovascular aging research. J Aging Res (2014) 0.77
Deficiency of sex hormones does not affect 17-ß-estradiol-induced coronary vasodilation in the isolated rat heart. Braz J Med Biol Res (2016) 0.76
Genistein from Vigna angularis Extends Lifespan in Caenorhabditis elegans. Biomol Ther (Seoul) (2015) 0.76
Effect of dihydrotestosterone on mouse embryonic stem cells exposed to H2O2-induced oxidative stress. J Vet Sci (2008) 0.76
Oestradiol levels and superoxide dismutase activity in age-related cataract: a case-control study. BMC Ophthalmol (2016) 0.75
Gonadal steroids negatively modulate oxidative stress in CBA/Ca female mice infected with P. berghei ANKA. Biomed Res Int (2014) 0.75
Time and dose-dependent effects of Labisia pumila on bone oxidative status of postmenopausal osteoporosis rat model. Nutrients (2014) 0.75
Activation of antioxidant defenses in whole saliva by psychosocial stress is more manifested in young women than in young men. PLoS One (2014) 0.75
Active paraplegics are protected against exercise-induced oxidative damage through the induction of antioxidant enzymes. Spinal Cord (2016) 0.75
Effect of Cross-Sex Hormonal Replacement on Antioxidant Enzymes in Rat Retroperitoneal Fat Adipocytes. Oxid Med Cell Longev (2016) 0.75
Estrogen inhibits starvation-induced apoptosis in osteocytes by a redox-independent process involving association of JNK and glutathione S-transferase P1-1. FEBS Open Bio (2017) 0.75
Association between serum γ-glutamyltranspeptidase and atherosclerosis: a population-based cross-sectional study. BMJ Open (2014) 0.75
Sex-specific differences in mitochondria biogenesis, morphology, respiratory function, and ROS homeostasis in young mouse heart and brain. Physiol Rep (2017) 0.75
Glutathione peroxidase 3 is a protective factor against acetaminophen‑induced hepatotoxicity in vivo and in vitro. Int J Mol Med (2017) 0.75
Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations. Free Radic Biol Med (2011) 3.58
Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance. Am J Clin Nutr (2008) 3.01
Telomerase reverse transcriptase delays aging in cancer-resistant mice. Cell (2008) 2.85
Room-air resuscitation causes less damage to heart and kidney than 100% oxygen. Am J Respir Crit Care Med (2005) 2.53
Oxidative stress in asphyxiated term infants resuscitated with 100% oxygen. J Pediatr (2003) 2.15
Oxidative stress is related to frailty, not to age or sex, in a geriatric population: lipid and protein oxidation as biomarkers of frailty. J Am Geriatr Soc (2014) 2.04
Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal. Circ Res (2004) 1.95
Mitochondria from females exhibit higher antioxidant gene expression and lower oxidative damage than males. Free Radic Biol Med (2003) 1.93
RNAPol-ChIP: a novel application of chromatin immunoprecipitation to the analysis of real-time gene transcription. Nucleic Acids Res (2004) 1.86
Vascular NAD(P)H oxidase activation in diabetes: a double-edged sword in redox signalling. Cardiovasc Res (2009) 1.82
Preterm resuscitation with low oxygen causes less oxidative stress, inflammation, and chronic lung disease. Pediatrics (2009) 1.82
Xanthine oxidase is involved in free radical production in type 1 diabetes: protection by allopurinol. Diabetes (2002) 1.67
Decreasing xanthine oxidase-mediated oxidative stress prevents useful cellular adaptations to exercise in rats. J Physiol (2005) 1.59
Pathological aspects of lipid peroxidation. Free Radic Res (2010) 1.56
A new model of oxidative stress in rat pups. Neonatology (2008) 1.55
[The emergent role of sarcopenia: Preliminary Report of the Observatory of Sarcopenia of the Spanish Society of Geriatrics and Gerontology]. Rev Esp Geriatr Gerontol (2011) 1.45
Dengue fever activates the L-arginine-nitric oxide pathway: an explanation for reduced aggregation of human platelets. Clin Exp Pharmacol Physiol (2008) 1.45
The role of mitochondrial oxidative stress in aging. Free Radic Biol Med (2003) 1.40
Glutathione is recruited into the nucleus in early phases of cell proliferation. J Biol Chem (2007) 1.35
Crosstalk between Nrf2 and the proteasome: therapeutic potential of Nrf2 inducers in vascular disease and aging. Int J Biochem Cell Biol (2012) 1.25
Endothelial dysfunction and reduced antioxidant protection in an animal model of the developmental origins of cardiovascular disease. J Physiol (2008) 1.23
Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo. Free Radic Biol Med (2011) 1.22
Impaired redox signaling and antioxidant gene expression in endothelial cells in diabetes: a role for mitochondria and the nuclear factor-E2-related factor 2-Kelch-like ECH-associated protein 1 defense pathway. Antioxid Redox Signal (2010) 1.19
A nuclear glutathione cycle within the cell cycle. Biochem J (2010) 1.18
Antenatal steroids and antioxidant enzyme activity in preterm infants: influence of gender and timing. Antioxid Redox Signal (2009) 1.17
Role of nuclear glutathione as a key regulator of cell proliferation. Mol Aspects Med (2009) 1.16
RasGrf1 deficiency delays aging in mice. Aging (Albany NY) (2011) 1.16
Recruitment of glutathione into the nucleus during cell proliferation adjusts whole-cell redox homeostasis in Arabidopsis thaliana and lowers the oxidative defence shield. Plant J (2010) 1.14
Dietary soy isoflavone induced increases in antioxidant and eNOS gene expression lead to improved endothelial function and reduced blood pressure in vivo. FASEB J (2005) 1.14
Mitochondrial oxidative stress and CD95 ligand: a dual mechanism for hepatocyte apoptosis in chronic alcoholism. Hepatology (2002) 1.14
Early activation of the p42/p44MAPK pathway mediates adenosine-induced nitric oxide production in human endothelial cells: a novel calcium-insensitive mechanism. FASEB J (2002) 1.13
Induction of heme oxygenase 1 by moderately oxidized low-density lipoproteins in human vascular smooth muscle cells: role of mitogen-activated protein kinases and Nrf2. Free Radic Biol Med (2005) 1.13
Interaction between cytokines and oxidative stress in acute pancreatitis. Curr Med Chem (2006) 1.12
Females live longer than males: role of oxidative stress. Curr Pharm Des (2011) 1.12
Genistein, a soy isoflavone, up-regulates expression of antioxidant genes: involvement of estrogen receptors, ERK1/2, and NFkappaB. FASEB J (2006) 1.12
Allopurinol and markers of muscle damage among participants in the Tour de France. JAMA (2003) 1.10
Vitamin E paradox in Alzheimer's disease: it does not prevent loss of cognition and may even be detrimental. J Alzheimers Dis (2009) 1.10
Why females live longer than males? Importance of the upregulation of longevity-associated genes by oestrogenic compounds. FEBS Lett (2005) 1.10
Ursodeoxycholic acid protects against secondary biliary cirrhosis in rats by preventing mitochondrial oxidative stress. Hepatology (2004) 1.10
Mitochondrial theory of aging: importance to explain why females live longer than males. Antioxid Redox Signal (2003) 1.09
Why females live longer than males: control of longevity by sex hormones. Sci Aging Knowledge Environ (2005) 1.08
Effect of simultaneous inhibition of TNF-alpha production and xanthine oxidase in experimental acute pancreatitis: the role of mitogen activated protein kinases. Ann Surg (2004) 1.08
Platelet nitric oxide synthesis in uremia and malnutrition: a role for L-arginine supplementation in vascular protection? Cardiovasc Res (2006) 1.07
Oxidative stress as a multiple effector in Fanconi anaemia clinical phenotype. Eur J Haematol (2005) 1.07
Mitochondria as sources and targets of damage in cellular aging. Clin Chem Lab Med (2012) 1.06
The depletion of nuclear glutathione impairs cell proliferation in 3t3 fibroblasts. PLoS One (2009) 1.06
Direct antioxidant and protective effect of estradiol on isolated mitochondria. Biochim Biophys Acta (2009) 1.05
Targeting the Nrf2-Keap1 antioxidant defence pathway for neurovascular protection in stroke. J Physiol (2011) 1.05
Cross-talk between oxidative stress and pro-inflammatory cytokines in acute pancreatitis: a key role for protein phosphatases. Curr Pharm Des (2009) 1.05
Mitochondrial involvement in non-alcoholic steatohepatitis. Mol Aspects Med (2007) 1.05
Effects of 4-hydroxynonenal on vascular endothelial and smooth muscle cell redox signaling and function in health and disease. Redox Biol (2013) 1.04
Estradiol or genistein prevent Alzheimer's disease-associated inflammation correlating with an increase PPAR gamma expression in cultured astrocytes. Brain Res (2009) 1.04
Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood-brain barrier disruption and neurological deficits in stroke. Free Radic Biol Med (2013) 1.03
Cardiovascular targets for estrogens and phytoestrogens: transcriptional regulation of nitric oxide synthase and antioxidant defense genes. Free Radic Biol Med (2007) 1.02
Dietary isoflavones and vascular protection: activation of cellular antioxidant defenses by SERMs or hormesis? Mol Aspects Med (2010) 1.01
Acute and chronic exposure to shear stress have opposite effects on endothelial permeability to macromolecules. Am J Physiol Heart Circ Physiol (2010) 1.00
Interaction between maternal and offspring diet to impair vascular function and oxidative balance in high fat fed male mice. PLoS One (2012) 0.99
Amyloid-β toxicity and tau hyperphosphorylation are linked via RCAN1 in Alzheimer's disease. J Alzheimers Dis (2011) 0.98
Modulation of antioxidant gene expression by 4-hydroxynonenal: atheroprotective role of the Nrf2/ARE transcription pathway. Redox Rep (2007) 0.98
Equol-stimulated mitochondrial reactive oxygen species activate endothelial nitric oxide synthase and redox signaling in endothelial cells: roles for F-actin and GPR30. Hypertension (2011) 0.97
Modulation of the L-arginine/nitric oxide signalling pathway in vascular endothelial cells. Biochem Soc Symp (2004) 0.96
Mitochondrial oxidant generation is involved in determining why females live longer than males. Front Biosci (2007) 0.95
Exercise-induced systemic effects in muscle-wasted patients with COPD. Med Sci Sports Exerc (2006) 0.95
Oxidative stress in Fanconi anaemia: from cells and molecules towards prospects in clinical management. Biol Chem (2012) 0.94
Nuclear glutathione. Biochim Biophys Acta (2012) 0.94
Centenarians, but not octogenarians, up-regulate the expression of microRNAs. Sci Rep (2012) 0.93
The isoflavone Equol mediates rapid vascular relaxation: Ca2+-independent activation of endothelial nitric-oxide synthase/Hsp90 involving ERK1/2 and Akt phosphorylation in human endothelial cells. J Biol Chem (2006) 0.93
Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer's disease: three partners in crime. Aging Cell (2011) 0.92