Published in Hum Mol Genet on June 01, 2005
Identification of novel FMR1 variants by massively parallel sequencing in developmentally delayed males. Am J Med Genet A (2010) 1.16
An origin of DNA replication in the promoter region of the human fragile X mental retardation (FMR1) gene. Mol Cell Biol (2006) 1.16
NF-Y, AP2, Nrf1 and Sp1 regulate the fragile X-related gene 2 (FXR2). Biochem J (2006) 0.88
The gene encoding the fragile X RNA-binding protein is controlled by nuclear respiratory factor 2 and the CREB family of transcription factors. Nucleic Acids Res (2006) 0.87
Bidirectional transcription of trinucleotide repeats: roles for excision repair. DNA Repair (Amst) (2013) 0.82
Single-Nucleotide Mutations in FMR1 Reveal Novel Functions and Regulatory Mechanisms of the Fragile X Syndrome Protein FMRP. J Exp Neurosci (2015) 0.76
Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. Cell Stem Cell (2008) 5.76
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype. EMBO J (2002) 5.07
Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity. Nat Genet (2005) 3.93
T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema. EMBO J (2003) 3.82
Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. Genes Dev (2007) 3.81
Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney. EMBO J (2006) 3.26
Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate. Dev Dyn (2002) 3.10
Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity. Genes Dev (2008) 2.91
Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development. Genes Dev (2003) 2.59
Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina. Nat Genet (2003) 2.50
Iridovirus and microsporidian linked to honey bee colony decline. PLoS One (2010) 2.50
Bronchoscopic lung volume reduction for end-stage emphysema: report on the first 98 patients. Chest (2006) 2.22
Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development. Development (2011) 1.92
Current views on the function of the lymphatic vasculature in health and disease. Genes Dev (2010) 1.84
Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype. Cancer Cell (2008) 1.82
Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors. Development (2002) 1.73
The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells. Genes Dev (2010) 1.73
Sox9 is expressed in mouse multipotent retinal progenitor cells and functions in Müller glial cell development. J Comp Neurol (2008) 1.65
Six3 activation of Pax6 expression is essential for mammalian lens induction and specification. EMBO J (2006) 1.64
Wnt1-Cre-mediated deletion of AP-2alpha causes multiple neural crest-related defects. Dev Biol (2004) 1.62
Transcription factor AP-2gamma is essential in the extra-embryonic lineages for early postimplantation development. Development (2002) 1.62
Matrix metalloproteinases in tumorigenesis: an evolving paradigm. Cell Mol Life Sci (2011) 1.60
The FXG: a presynaptic fragile X granule expressed in a subset of developing brain circuits. J Neurosci (2009) 1.60
Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly. Dev Cell (2008) 1.57
Tbx1 expression in pharyngeal epithelia is necessary for pharyngeal arch artery development. Development (2005) 1.57
Lymphatic endothelial progenitors bud from the cardinal vein and intersomitic vessels in mammalian embryos. Blood (2012) 1.56
Prox1 is an early specific marker for the developing liver and pancreas in the mammalian foregut endoderm. Mech Dev (2002) 1.55
Defective or effective? Mutualistic interactions between virus genotypes. Proc Biol Sci (2003) 1.53
Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis. PLoS Biol (2010) 1.51
Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis. Development (2006) 1.50
Threshold-specific requirements for Bmp4 in mandibular development. Dev Biol (2005) 1.50
Biomedical discovery acceleration, with applications to craniofacial development. PLoS Comput Biol (2009) 1.49
Addition of inhaled corticosteroids to systemic immunosuppression after lung transplantation: a double-blind, placebo-controlled trial. Transplantation (2002) 1.48
Up-regulation of gastric cancer cell invasion by Twist is accompanied by N-cadherin and fibronectin expression. Biochem Biophys Res Commun (2007) 1.45
Regulation of a remote Shh forebrain enhancer by the Six3 homeoprotein. Nat Genet (2008) 1.45
Atrial fibrillation following lung transplantation: double but not single lung transplant is associated with long-term freedom from paroxysmal atrial fibrillation. Eur Heart J (2010) 1.43
Induction of neural crest in Xenopus by transcription factor AP2alpha. Proc Natl Acad Sci U S A (2003) 1.43
A conserved Pbx-Wnt-p63-Irf6 regulatory module controls face morphogenesis by promoting epithelial apoptosis. Dev Cell (2011) 1.43
Prox1 activity controls pancreas morphogenesis and participates in the production of "secondary transition" pancreatic endocrine cells. Dev Biol (2005) 1.41
Visual experience regulates transient expression and dendritic localization of fragile X mental retardation protein. J Neurosci (2004) 1.39
AP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermis. J Cell Biol (2006) 1.38
Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lymphovenous valves. Genes Dev (2011) 1.36
Lim1 is essential for the correct laminar positioning of retinal horizontal cells. J Neurosci (2007) 1.35
Prox1 expression patterns in the developing and adult murine brain. Dev Dyn (2007) 1.34
Tissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesis. Genes Dev (2006) 1.34
Development of the mammalian lymphatic vasculature. J Clin Invest (2014) 1.34
Distinct developmental programs require different levels of Bmp signaling during mouse retinal development. Development (2005) 1.33
AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis. J Cell Biol (2008) 1.33
Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life. J Clin Invest (2014) 1.30
Transcription Factors Pax6 and AP-2alpha Interact To Coordinate Corneal Epithelial Repair by Controlling Expression of Matrix Metalloproteinase Gelatinase B. Mol Cell Biol (2004) 1.29
Thrombospondin-1 selectively inhibits early-stage carcinogenesis and angiogenesis but not tumor lymphangiogenesis and lymphatic metastasis in transgenic mice. Oncogene (2002) 1.27
Genetic structure of a Spodoptera frugiperda nucleopolyhedrovirus population: high prevalence of deletion genotypes. Appl Environ Microbiol (2004) 1.24
Biglycan recruits utrophin to the sarcolemma and counters dystrophic pathology in mdx mice. Proc Natl Acad Sci U S A (2010) 1.24
Neural crest and ectodermal cells intermix in the nasal placode to give rise to GnRH-1 neurons, sensory neurons, and olfactory ensheathing cells. J Neurosci (2011) 1.22
Prox1 maintains muscle structure and growth in the developing heart. Development (2008) 1.21
Novel lethal mouse mutants produced in balancer chromosome screens. Gene Expr Patterns (2006) 1.21
Hypermethylation of a small CpGuanine-rich region correlates with loss of activator protein-2alpha expression during progression of breast cancer. Cancer Res (2004) 1.20
Age-related stereotypes: a comparison of American and Chinese cultures. Gerontology (2006) 1.20
Finally, a sense of closure? Animal models of human ventral body wall defects. Bioessays (2004) 1.19
Requirement for AP-2alpha in cardiac outflow tract morphogenesis. Mech Dev (2002) 1.18
Transcription factor AP-2 is an essential and direct regulator of epidermal development in Xenopus. Dev Biol (2002) 1.17
Neuroretina specification in mouse embryos requires Six3-mediated suppression of Wnt8b in the anterior neural plate. J Clin Invest (2010) 1.17
Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon. Development (2007) 1.17
Functional importance of deletion mutant genotypes in an insect nucleopolyhedrovirus population. Appl Environ Microbiol (2005) 1.16
Cloning and characterization of the mouse AP-2 epsilon gene: a novel family member expressed in the developing olfactory bulb. Mol Cell Neurosci (2003) 1.16
Plasticity of button-like junctions in the endothelium of airway lymphatics in development and inflammation. Am J Pathol (2012) 1.15
Physical and partial genetic map of Spodoptera frugiperda nucleopolyhedrovirus (SfMNPV) genome. Virus Genes (2005) 1.15
Eomesodermin, a target gene of Pou4f2, is required for retinal ganglion cell and optic nerve development in the mouse. Development (2007) 1.15
Leveraging existing biological knowledge in the identification of candidate genes for facial dysmorphology. BMC Bioinformatics (2009) 1.13
Mixed genotype transmission bodies and virions contribute to the maintenance of diversity in an insect virus. Proc Biol Sci (2009) 1.12
Pathogenesis of holoprosencephaly. J Clin Invest (2009) 1.12
Spatial and temporal analysis of gene expression during growth and fusion of the mouse facial prominences. PLoS One (2009) 1.11
Loss of AP-2alpha impacts multiple aspects of ventral body wall development and closure. Dev Biol (2004) 1.11
Transient up-regulation of biglycan during skeletal muscle regeneration: delayed fiber growth along with decorin increase in biglycan-deficient mice. Dev Biol (2004) 1.10
Acute fibrinoid organizing pneumonia after lung transplantation. Am J Respir Crit Care Med (2013) 1.10
Ectodermal Wnt/β-catenin signaling shapes the mouse face. Dev Biol (2010) 1.10
Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype. Dev Dyn (2008) 1.08
Blockade of GRP78 sensitizes breast cancer cells to microtubules-interfering agents that induce the unfolded protein response. J Cell Mol Med (2009) 1.08
Dynamics of deletion genotypes in an experimental insect virus population. Proc Biol Sci (2006) 1.08
TAp63alpha induces AP-2gamma as an early event in epidermal morphogenesis. Dev Biol (2005) 1.08
Somal positioning and dendritic growth of horizontal cells are regulated by interactions with homotypic neighbors. Eur J Neurosci (2008) 1.07
Fgf15 is required for proper morphogenesis of the mouse cardiac outflow tract. Genesis (2005) 1.06
BMP signaling through ACVRI is required for left-right patterning in the early mouse embryo. Dev Biol (2004) 1.06
FGFR1 function at the earliest stages of mouse limb development plays an indispensable role in subsequent autopod morphogenesis. Development (2005) 1.05
Systematic mapping of fragile X granules in the mouse brain reveals a potential role for presynaptic FMRP in sensorimotor functions. J Comp Neurol (2012) 1.05
Conditional deletion of activating protein 2alpha (AP-2alpha) in the developing retina demonstrates non-cell-autonomous roles for AP-2alpha in optic cup development. Mol Cell Biol (2007) 1.04
A Cenozoic record of the equatorial Pacific carbonate compensation depth. Nature (2012) 1.04
Blood flow reprograms lymphatic vessels to blood vessels. J Clin Invest (2012) 1.04
Biglycan regulates the expression and sarcolemmal localization of dystrobrevin, syntrophin, and nNOS. FASEB J (2006) 1.03
Biglycan is an extracellular MuSK binding protein important for synapse stability. J Neurosci (2012) 1.02
Targeted deletion of AP-2alpha leads to disruption in corneal epithelial cell integrity and defects in the corneal stroma. Invest Ophthalmol Vis Sci (2005) 1.02
Bone morphogenetic proteins, eye patterning, and retinocollicular map formation in the mouse. J Neurosci (2008) 1.02
Six2 functions redundantly immediately downstream of Hoxa2. Development (2008) 1.02
Specification of the otic placode depends on Sox9 function in Xenopus. Development (2004) 1.02
C3d and C4d deposition early after lung transplantation. J Heart Lung Transplant (2008) 1.01
The spatial patterning of mouse cone opsin expression is regulated by bone morphogenetic protein signaling through downstream effector COUP-TF nuclear receptors. J Neurosci (2009) 1.00