Published in Development on January 26, 2005
Eye morphogenesis and patterning of the optic vesicle. Curr Top Dev Biol (2010) 1.60
The BMP ligand Gbb gates the expression of synaptic homeostasis independent of synaptic growth control. Neuron (2007) 1.48
The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation. Dev Biol (2009) 1.25
The level of BMP4 signaling is critical for the regulation of distinct T-box gene expression domains and growth along the dorso-ventral axis of the optic cup. BMC Dev Biol (2006) 1.19
BMPER is a conserved regulator of hematopoietic and vascular development in zebrafish. J Mol Cell Cardiol (2007) 1.17
Lhx2 links the intrinsic and extrinsic factors that control optic cup formation. Development (2009) 1.11
Ocular coloboma and dorsoventral neuroretinal patterning defects in Lrp6 mutant eyes. Dev Dyn (2008) 1.05
Negative regulation of Vsx1 by its paralog Chx10/Vsx2 is conserved in the vertebrate retina. Brain Res (2007) 1.02
Bone morphogenetic proteins, eye patterning, and retinocollicular map formation in the mouse. J Neurosci (2008) 1.02
Canonical Wnt signaling is required for the maintenance of dorsal retinal identity. Development (2008) 1.02
The spatial patterning of mouse cone opsin expression is regulated by bone morphogenetic protein signaling through downstream effector COUP-TF nuclear receptors. J Neurosci (2009) 1.00
Eye and neural defects associated with loss of GDF6. BMC Dev Biol (2006) 1.00
BMP signaling mediates stem/progenitor cell-induced retina regeneration. Proc Natl Acad Sci U S A (2007) 0.96
Genetic interaction between Bmp2 and Bmp4 reveals shared functions during multiple aspects of mouse organogenesis. Mech Dev (2008) 0.96
Bmp2 and Bmp4 genetically interact to support multiple aspects of mouse development including functional heart development. Genesis (2009) 0.96
Lhx2 is required for patterning and expansion of a distinct progenitor cell population committed to eye development. PLoS One (2011) 0.90
Loss of Tbx2 delays optic vesicle invagination leading to small optic cups. Dev Biol (2009) 0.89
FGF-mediated induction of ciliary body tissue in the chick eye. Dev Biol (2006) 0.88
Meis1 specifies positional information in the retina and tectum to organize the zebrafish visual system. Neural Dev (2010) 0.88
A balance of FGF and BMP signals regulates cell cycle exit and Equarin expression in lens cells. Mol Biol Cell (2012) 0.85
Activation of BMP-Smad1/5/8 signaling promotes survival of retinal ganglion cells after damage in vivo. PLoS One (2012) 0.85
Id2a functions to limit Notch pathway activity and thereby influence the transition from proliferation to differentiation of retinoblasts during zebrafish retinogenesis. Dev Biol (2012) 0.84
Axon-bearing and axon-less horizontal cell subtypes are generated consecutively during chick retinal development from progenitors that are sensitive to follistatin. BMC Dev Biol (2008) 0.84
Sma- and Mad-related protein 7 (Smad7) is required for embryonic eye development in the mouse. J Biol Chem (2013) 0.84
Negative and positive auto-regulation of BMP expression in early eye development. Dev Biol (2015) 0.84
Extraocular ectoderm triggers dorsal retinal fate during optic vesicle evagination in zebrafish. Dev Biol (2012) 0.80
Bmp4 from the optic vesicle specifies murine retina formation. Dev Biol (2015) 0.80
Adult-specific systemic over-expression reveals novel in vivo effects of the soluble forms of ActRIIA, ActRIIB and BMPRII. PLoS One (2013) 0.80
Neural retina identity is specified by lens-derived BMP signals. Development (2015) 0.79
Bone morphogenetic protein 4 (BMP4) signaling in retinoblastoma cells. Int J Biol Sci (2010) 0.79
Tissue specific characterisation of Lim-kinase 1 expression during mouse embryogenesis. Gene Expr Patterns (2010) 0.79
Challenges in the study of neuronal differentiation: a view from the embryonic eye. Dev Dyn (2005) 0.78
Smad4 is required predominantly in the developmental processes dependent on the BMP branch of the TGF-β signaling system in the embryonic mouse retina. Invest Ophthalmol Vis Sci (2011) 0.78
Consequences of axon guidance defects on the development of retinotopic receptive fields in the mouse colliculus. J Physiol (2009) 0.78
COUP-TFs and eye development. Biochim Biophys Acta (2014) 0.77
Strategies for designing transgenic DNA constructs. Methods Mol Biol (2013) 0.77
Differential requirement of bone morphogenetic protein receptors Ia (ALK3) and Ib (ALK6) in early embryonic patterning and neural crest development. BMC Dev Biol (2016) 0.76
Extramacrochaetae functions in dorsal-ventral patterning of Drosophila imaginal discs. Development (2015) 0.76
Stem Cell Therapy for Treatment of Ocular Disorders. Stem Cells Int (2016) 0.76
Dorsoventral patterning of the Xenopus eye involves differential temporal changes in the response of optic stalk and retinal progenitors to Hh signalling. Neural Dev (2015) 0.75
Control of lens development by Lhx2-regulated neuroretinal FGFs. Development (2016) 0.75
BMP-induced reprograming of the retina into RPE requires WNT signalling in the developing chick optic cup. Biol Open (2017) 0.75
BmpR1A is a major type 1 BMP receptor for BMP-Smad signaling during skull development. Dev Biol (2017) 0.75
Identification of the haematopoietic stem cell niche and control of the niche size. Nature (2003) 18.17
Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction. Proc Natl Acad Sci U S A (2003) 7.87
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling. Nat Genet (2004) 7.37
Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. Cell Stem Cell (2008) 5.76
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype. EMBO J (2002) 5.07
Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development. Development (2003) 4.31
BMP type I receptor inhibition reduces heterotopic [corrected] ossification. Nat Med (2008) 4.20
Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells. Mol Cell Biol (2008) 4.07
Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity. Nat Genet (2005) 3.93
T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema. EMBO J (2003) 3.82
Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. Genes Dev (2007) 3.81
Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development. Development (2004) 3.46
Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney. EMBO J (2006) 3.26
Deletion of dentin matrix protein-1 leads to a partial failure of maturation of predentin into dentin, hypomineralization, and expanded cavities of pulp and root canal during postnatal tooth development. J Biol Chem (2004) 3.21
Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate. Dev Dyn (2002) 3.10
Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3. Proc Natl Acad Sci U S A (2002) 2.99
Abnormal conduction and morphology in the atrioventricular node of mice with atrioventricular canal targeted deletion of Alk3/Bmpr1a receptor. Circulation (2007) 2.93
Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity. Genes Dev (2008) 2.91
Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo. Proc Natl Acad Sci U S A (2005) 2.82
Requirement of Bmpr1a for Müllerian duct regression during male sexual development. Nat Genet (2002) 2.75
Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat. Nature (2013) 2.70
Dmp1-deficient mice display severe defects in cartilage formation responsible for a chondrodysplasia-like phenotype. J Biol Chem (2004) 2.70
Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development. Genes Dev (2003) 2.59
Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina. Nat Genet (2003) 2.50
Distinct functions for Bmp signaling in lip and palate fusion in mice. Development (2005) 2.46
Autoregulation of neurogenesis by GDF11. Neuron (2003) 2.40
Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-γ agonists. Nat Med (2011) 2.40
BMP4-BMPR1A signaling in beta cells is required for and augments glucose-stimulated insulin secretion. Cell Metab (2007) 2.39
Mutations in Drosophila sec15 reveal a function in neuronal targeting for a subset of exocyst components. Neuron (2005) 2.33
BMP4 supports self-renewal of embryonic stem cells by inhibiting mitogen-activated protein kinase pathways. Proc Natl Acad Sci U S A (2004) 2.25
BMP signaling and early embryonic patterning. Cytokine Growth Factor Rev (2005) 2.25
BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation. Development (2009) 2.21
Nonsteroidal anti-inflammatory drug-activated gene-1 over expression in transgenic mice suppresses intestinal neoplasia. Gastroenterology (2006) 2.21
Histone demethylase JHDM2A is critical for Tnp1 and Prm1 transcription and spermatogenesis. Nature (2007) 2.21
Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion. Stem Cells (2006) 2.09
Bone morphogenetic protein signaling is essential for terminal differentiation of the intestinal secretory cell lineage. Gastroenterology (2007) 2.07
BMP receptor signaling is required for postnatal maintenance of articular cartilage. PLoS Biol (2004) 2.05
GDF11 controls the timing of progenitor cell competence in developing retina. Science (2005) 2.04
Retinal waves coordinate patterned activity throughout the developing visual system. Nature (2012) 2.00
CCN2 is necessary for adhesive responses to transforming growth factor-beta1 in embryonic fibroblasts. J Biol Chem (2006) 1.96
BMP signaling is required for septation of the outflow tract of the mammalian heart. Development (2003) 1.95
BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium. Development (2004) 1.93
Evidence for an instructive role of retinal activity in retinotopic map refinement in the superior colliculus of the mouse. J Neurosci (2005) 1.93
Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development. Development (2011) 1.92
Multiple functions of BMPs in chondrogenesis. J Cell Biochem (2004) 1.92
BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development (2008) 1.86
Current views on the function of the lymphatic vasculature in health and disease. Genes Dev (2010) 1.84
Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol (2006) 1.83
CCN2 (connective tissue growth factor) promotes fibroblast adhesion to fibronectin. Mol Biol Cell (2004) 1.83
Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype. Cancer Cell (2008) 1.82
Cardiac muscle plasticity in adult and embryo by heart-derived progenitor cells. Ann N Y Acad Sci (2004) 1.80
A digital atlas to characterize the mouse brain transcriptome. PLoS Comput Biol (2005) 1.78
Laminar and columnar development of barrel cortex relies on thalamocortical neurotransmission. Neuron (2013) 1.74
The immune protein CD3zeta is required for normal development of neural circuits in the retina. Neuron (2010) 1.74
Cell mixing at a neural crest-mesoderm boundary and deficient ephrin-Eph signaling in the pathogenesis of craniosynostosis. Hum Mol Genet (2006) 1.74
Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors. Development (2002) 1.73
Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin family. Mol Cell Biol (2004) 1.73
The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells. Genes Dev (2010) 1.73
Mutation discovery in mice by whole exome sequencing. Genome Biol (2011) 1.69
Generation of a mouse with conditionally activated signaling through the BMP receptor, ALK2. Genesis (2006) 1.67
Outflow tract cushions perform a critical valve-like function in the early embryonic heart requiring BMPRIA-mediated signaling in cardiac neural crest. Am J Physiol Heart Circ Physiol (2009) 1.66
State-dependent bidirectional modification of somatic inhibition in neocortical pyramidal cells. Neuron (2008) 1.66
Sox9 is expressed in mouse multipotent retinal progenitor cells and functions in Müller glial cell development. J Comp Neurol (2008) 1.65
Six3 activation of Pax6 expression is essential for mammalian lens induction and specification. EMBO J (2006) 1.64
BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development (2006) 1.59
Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly. Dev Cell (2008) 1.57
Tbx1 expression in pharyngeal epithelia is necessary for pharyngeal arch artery development. Development (2005) 1.57
CCN2 is necessary for the function of mouse embryonic fibroblasts. Exp Cell Res (2006) 1.57
Lymphatic endothelial progenitors bud from the cardinal vein and intersomitic vessels in mammalian embryos. Blood (2012) 1.56
Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation. Development (2006) 1.56
Prox1 is an early specific marker for the developing liver and pancreas in the mammalian foregut endoderm. Mech Dev (2002) 1.55
Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb. Genes Dev (2003) 1.55
CCN family 2/connective tissue growth factor modulates BMP signalling as a signal conductor, which action regulates the proliferation and differentiation of chondrocytes. J Biochem (2008) 1.55
Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts. J Bone Miner Res (2010) 1.54
Disruption of BMP signaling in osteoblasts through type IA receptor (BMPRIA) increases bone mass. J Bone Miner Res (2008) 1.54
Developmental homeostasis of mouse retinocollicular synapses. J Neurosci (2007) 1.52
Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage. J Bone Miner Res (2008) 1.51
Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis. PLoS Biol (2010) 1.51
Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis. Development (2006) 1.50
Threshold-specific requirements for Bmp4 in mandibular development. Dev Biol (2005) 1.50
BMP signalling inhibits premature neural differentiation in the mouse embryo. Development (2007) 1.49
BMP signaling is required locally to pattern the dorsal telencephalic midline. Neuron (2002) 1.49
Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus. Circ Res (2005) 1.48
Regulation of a remote Shh forebrain enhancer by the Six3 homeoprotein. Nat Genet (2008) 1.45
BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development. J Cell Sci (2011) 1.44
BMP signaling stimulates cellular differentiation at multiple steps during cartilage development. Proc Natl Acad Sci U S A (2005) 1.44
Positional cloning of the gene LIMBIN responsible for bovine chondrodysplastic dwarfism. Proc Natl Acad Sci U S A (2002) 1.42
Prox1 activity controls pancreas morphogenesis and participates in the production of "secondary transition" pancreatic endocrine cells. Dev Biol (2005) 1.41
Adenylyl cyclase I regulates AMPA receptor trafficking during mouse cortical 'barrel' map development. Nat Neurosci (2003) 1.41
An instructive role for patterned spontaneous retinal activity in mouse visual map development. Neuron (2011) 1.38
Regulation of outgrowth and apoptosis for the terminal appendage: external genitalia development by concerted actions of BMP signaling [corrected]. Development (2003) 1.38
Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth. Development (2002) 1.37
Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2. Development (2011) 1.37
Essential functions of Alk3 during AV cushion morphogenesis in mouse embryonic hearts. Dev Biol (2006) 1.37
Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lymphovenous valves. Genes Dev (2011) 1.36
BMP signals control limb bud interdigital programmed cell death by regulating FGF signaling. Development (2007) 1.35