Published in J Orthop Res on June 04, 2005
The role of oxygen during fracture healing. Bone (2012) 2.21
A SHH-responsive signaling center in the forebrain regulates craniofacial morphogenesis via the facial ectoderm. Development (2008) 1.93
Wnt3a reestablishes osteogenic capacity to bone grafts from aged animals. J Bone Joint Surg Am (2013) 1.52
Osteoblast expression of an engineered Gs-coupled receptor dramatically increases bone mass. Proc Natl Acad Sci U S A (2008) 1.46
Heterochronic parabiosis for the study of the effects of aging on stem cells and their niches. Cell Cycle (2012) 1.42
Ischemia leads to delayed union during fracture healing: a mouse model. J Orthop Res (2007) 1.34
Reduced COX-2 expression in aged mice is associated with impaired fracture healing. J Bone Miner Res (2009) 1.31
Role of matrix metalloproteinase 13 in both endochondral and intramembranous ossification during skeletal regeneration. PLoS One (2007) 1.29
Unique organization of the frontonasal ectodermal zone in birds and mammals. Dev Biol (2008) 1.29
Action of IL-1beta during fracture healing. J Orthop Res (2010) 1.26
Multiple roles for CCR2 during fracture healing. Dis Model Mech (2010) 1.26
Bone morphogenetic protein 2 stimulates endochondral ossification by regulating periosteal cell fate during bone repair. Bone (2010) 1.26
Current insights on the regenerative potential of the periosteum: molecular, cellular, and endogenous engineering approaches. J Orthop Res (2012) 1.21
Effect of age on vascularization during fracture repair. J Orthop Res (2008) 1.19
Transplantation of mesenchymal stem cells from young donors delays aging in mice. Sci Rep (2011) 1.13
Mesenchyme-dependent BMP signaling directs the timing of mandibular osteogenesis. Development (2008) 1.11
Rejuvenation of the inflammatory system stimulates fracture repair in aged mice. J Orthop Res (2010) 1.08
Assessing angiogenesis during fracture healing. Iowa Orthop J (2006) 1.04
The promotion of bone healing by progranulin, a downstream molecule of BMP-2, through interacting with TNF/TNFR signaling. Biomaterials (2013) 1.03
Tibial fracture decreases oxygen levels at the site of injury. Iowa Orthop J (2008) 1.01
Effects of delayed stabilization on fracture healing. J Orthop Res (2007) 0.97
Effect of bone morphogenetic protein signaling on development of the jaw skeleton. Dev Dyn (2008) 0.95
Periosteum: biology and applications in craniofacial bone regeneration. J Dent Res (2013) 0.93
Role of Nanog in the maintenance of marrow stromal stem cells during post natal bone regeneration. Biochem Biophys Res Commun (2011) 0.92
Gs G protein-coupled receptor signaling in osteoblasts elicits age-dependent effects on bone formation. J Bone Miner Res (2010) 0.92
Delayed bone regeneration is linked to chronic inflammation in murine muscular dystrophy. J Bone Miner Res (2014) 0.92
MMP9 regulates the cellular response to inflammation after skeletal injury. Bone (2012) 0.91
Runx1 dose-dependently regulates endochondral ossification during skeletal development and fracture healing. J Bone Miner Res (2012) 0.91
Experimental trauma models: an update. J Biomed Biotechnol (2011) 0.89
Recombinant human bone morphogenetic protein-7 enhances fracture healing in an ischemic environment. J Orthop Res (2010) 0.89
Fractures in geriatric mice show decreased callus expansion and bone volume. Clin Orthop Relat Res (2014) 0.89
Aging, inflammation, stem cells, and bone healing. Stem Cell Res Ther (2016) 0.87
Aging periosteal progenitor cells have reduced regenerative responsiveness to bone injury and to the anabolic actions of PTH 1-34 treatment. Bone (2014) 0.86
Upregulation of inflammatory genes and downregulation of sclerostin gene expression are key elements in the early phase of fragility fracture healing. PLoS One (2011) 0.85
Modulation of macrophage activity during fracture repair has differential effects in young adult and elderly mice. J Orthop Trauma (2014) 0.85
Establishment of a femoral critical-size bone defect model in immunodeficient mice. J Surg Res (2012) 0.83
Is the expression of Transforming Growth Factor-Beta1 after fracture of long bones solely influenced by the healing process? Int Orthop (2012) 0.83
Impaired remodeling phase of fracture repair in the absence of matrix metalloproteinase-2. Dis Model Mech (2010) 0.82
Oblique closing wedge osteotomy and lateral plating for cubitus varus in adults. Clin Orthop Relat Res (2008) 0.81
Absence of beta3 integrin accelerates early skeletal repair. J Orthop Res (2010) 0.79
A sheep model for cancellous bone healing. Front Surg (2014) 0.78
Endochondral ossification for enhancing bone regeneration: converging native extracellular matrix biomaterials and developmental engineering in vivo. Tissue Eng Part B Rev (2014) 0.78
A surgical procedure for resecting the mouse rib: a model for large-scale long bone repair. J Vis Exp (2015) 0.77
Overview of biological mechanisms and applications of three murine models of bone repair: closed fracture with intramedullary fixation, distraction osteogenesis, and marrow ablation by reaming. Curr Protoc Mouse Biol (2015) 0.76
Cartilage to bone transformation during fracture healing is coordinated by the invading vasculature and induction of the core pluripotency genes. Development (2017) 0.76
Vascular endothelial growth factor improves bone repair in a murine nonunion model. Iowa Orthop J (2012) 0.76
Future Treatment Strategies for Delayed Bone Healing: An Osteoimmunologic Approach. J Am Acad Orthop Surg (2016) 0.75
Comparison of Efficacy of Endogenous and Exogenous IGF-I in Stimulating Matrix Production in Neonatal and Mature Chondrocytes. Cartilage (2015) 0.75
Time-Dependent Changes in T1 during Fracture Healing in Juvenile Rats: A Quantitative MR Approach. PLoS One (2016) 0.75
Generation of closed transverse fractures in small animals. Methods Mol Biol (2014) 0.75
Subperiosteal preparation using a new piezoelectric device: a histological examination. GMS Interdiscip Plast Reconstr Surg DGPW (2014) 0.75
A simple critical-sized femoral defect model in mice. J Vis Exp (2015) 0.75
Inhibition of Midkine Augments Osteoporotic Fracture Healing. PLoS One (2016) 0.75
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
Prevention of venous thromboembolism. Chest (2001) 5.59
Risk of mortality following clinical fractures. Osteoporos Int (2000) 3.76
Age-related osteogenic potential of mesenchymal stromal stem cells from human vertebral bone marrow. J Bone Miner Res (1999) 3.05
Rate of mortality for elderly patients after fracture of the hip in the 1980's. J Bone Joint Surg Am (1987) 2.63
Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications. Curr Opin Pharmacol (2004) 2.52
Altered fracture repair in the absence of MMP9. Development (2003) 2.41
Number of osteoprogenitor cells in human bone marrow markedly decreases after skeletal maturation. J Bone Miner Metab (1999) 1.74
Age-related changes in osteogenic stem cells in mice. J Bone Miner Res (1996) 1.42
The chondrogenic potential of periosteum decreases with age. J Orthop Res (2001) 1.28
Gene expression in older rats with delayed union of femoral fractures. J Bone Joint Surg Am (2003) 1.24
Predictors of outcome of floating knee injuries in adults: 89 patients followed for 2-12 years. Acta Orthop Scand (2001) 1.18
Star volume of marrow space and trabeculae of the first lumbar vertebra: sampling efficiency and biological variation. Bone (1989) 1.18
Evaluation of functional outcome of the floating knee injury using multivariate analysis. Arch Orthop Trauma Surg (2002) 1.18
Age and ovariectomy impair both the normalization of mechanical properties and the accretion of mineral by the fracture callus in rats. J Orthop Res (2001) 1.17
Hip fractures. An epidemiological review. Bull Hosp Jt Dis (1999) 1.15
The effect of aging on fracture healing in the rat. Calcif Tissue Int (1989) 1.10
Monitoring and healing analysis of 100 tibial shaft fractures. Langenbecks Arch Surg (2002) 1.02
The effect of age on gene expression in adult and juvenile rats following femoral fracture. J Orthop Trauma (2003) 0.98
Proliferation, differentiation and self-renewal of osteoprogenitors in vertebral cell populations from aged and young female rats. Mech Ageing Dev (2003) 0.94
1,25(OH)2D3 inhibits bone marrow adipogenesis in senescence accelerated mice (SAM-P/6) by decreasing the expression of peroxisome proliferator-activated receptor gamma 2 (PPARgamma2). Exp Gerontol (2004) 0.90
Myotube heterogeneity in developing chick craniofacial skeletal muscles. Dev Dyn (1999) 0.87
Telomerized presenescent osteoblasts prevent bone mass loss in vivo. Gene Ther (2004) 0.87
Electron microscopic and histologic studies on fracture repair in old and young rats. Acta Chir Scand Suppl (1966) 0.82
Altered fracture repair in the absence of MMP9. Development (2003) 2.41
The role of oxygen during fracture healing. Bone (2012) 2.21
Molecular interactions coordinating the development of the forebrain and face. Dev Biol (2005) 2.12
Deciphering the Palimpsest: Studying the Relationship Between Morphological Integration and Phenotypic Covariation. Evol Biol (2009) 2.07
A zone of frontonasal ectoderm regulates patterning and growth in the face. Development (2003) 2.04
Variability in the assessment of fracture-healing in orthopaedic trauma studies. J Bone Joint Surg Am (2008) 1.97
A SHH-responsive signaling center in the forebrain regulates craniofacial morphogenesis via the facial ectoderm. Development (2008) 1.93
A model for intramembranous ossification during fracture healing. J Orthop Res (2002) 1.82
Temporal perturbations in sonic hedgehog signaling elicit the spectrum of holoprosencephaly phenotypes. J Clin Invest (2004) 1.74
Distinguishing the contributions of the perichondrium, cartilage, and vascular endothelium to skeletal development. Dev Biol (2004) 1.64
Heterotopic ossification in orthopaedic trauma. J Orthop Trauma (2012) 1.63
SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1. Hum Mol Genet (2002) 1.53
Quantitative analyses link modulation of sonic hedgehog signaling to continuous variation in facial growth and shape. Development (2010) 1.49
The Chitranjan Ranawat Award: fate of two-stage reimplantation after failed irrigation and débridement for periprosthetic knee infection. Clin Orthop Relat Res (2011) 1.35
Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development. Development (2005) 1.34
Ischemia leads to delayed union during fracture healing: a mouse model. J Orthop Res (2007) 1.34
Role of matrix metalloproteinase 13 in both endochondral and intramembranous ossification during skeletal regeneration. PLoS One (2007) 1.29
Unique organization of the frontonasal ectodermal zone in birds and mammals. Dev Biol (2008) 1.29
Action of IL-1beta during fracture healing. J Orthop Res (2010) 1.26
Multiple roles for CCR2 during fracture healing. Dis Model Mech (2010) 1.26
Mechanisms that underlie co-variation of the brain and face. Genesis (2011) 1.26
Stage-dependent craniofacial defects resulting from Sprouty2 overexpression. Dev Dyn (2007) 1.21
Signaling by bone morphogenetic proteins directs formation of an ectodermal signaling center that regulates craniofacial development. Dev Biol (2007) 1.20
Strain in the median and ulnar nerves during upper-extremity positioning. J Hand Surg Am (2002) 1.20
Outcome assessment in clinical trials of fracture-healing. J Bone Joint Surg Am (2008) 1.19
Stem cell-derived endochondral cartilage stimulates bone healing by tissue transformation. J Bone Miner Res (2014) 1.19
Effect of age on vascularization during fracture repair. J Orthop Res (2008) 1.19
Expression of angiogenesis-related genes during retinal development. Gene Expr Patterns (2005) 1.17
Embryonic bauplans and the developmental origins of facial diversity and constraint. Development (2014) 1.13
Immunolocalization of BMPs, BMP antagonists, receptors, and effectors during fracture repair. Bone (2009) 1.12
Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J Med Chem (2009) 1.12
Measuring the attitudes and impact of the eighty-hour workweek rules on orthopaedic surgery residents. J Bone Joint Surg Am (2007) 1.11
Characterization of a human rhomboid homolog, p100hRho/RHBDF1, which interacts with TGF-alpha family ligands. Dev Dyn (2005) 1.09
Rejuvenation of the inflammatory system stimulates fracture repair in aged mice. J Orthop Res (2010) 1.08
Fixation of osteoporotic distal fibula fractures: A biomechanical comparison of locking versus conventional plates. J Foot Ankle Surg (2007) 1.06
Assessing angiogenesis during fracture healing. Iowa Orthop J (2006) 1.04
Injectable skeletal muscle matrix hydrogel promotes neovascularization and muscle cell infiltration in a hindlimb ischemia model. Eur Cell Mater (2012) 1.03
Wilms tumor survival in Kenya. J Pediatr Surg (2013) 1.03
Screening for phospholipidosis induced by central nervous drugs: comparing the predictivity of an in vitro assay to high throughput in silico assays. Toxicol In Vitro (2010) 1.02
Epigenetic integration of the developing brain and face. Dev Dyn (2011) 1.02
Tibial fracture decreases oxygen levels at the site of injury. Iowa Orthop J (2008) 1.01
Injectable hydrogel scaffold from decellularized human lipoaspirate. Acta Biomater (2010) 1.00
Mepe is expressed during skeletal development and regeneration. Histochem Cell Biol (2004) 1.00
Single-step capture and sequencing of natural DNA for detection of BRCA1 mutations. Genome Res (2011) 0.99
Delayed internal fixation of femoral shaft fracture reduces mortality among patients with multisystem trauma. J Bone Joint Surg Am (2009) 0.99
Effects of delayed stabilization on fracture healing. J Orthop Res (2007) 0.97
Necrotizing soft tissue infections of the extremities and back. Clin Orthop Relat Res (2006) 0.96
Effect of bone morphogenetic protein signaling on development of the jaw skeleton. Dev Dyn (2008) 0.95
Signaling by SHH rescues facial defects following blockade in the brain. Dev Dyn (2012) 0.95
Mechanical stability affects angiogenesis during early fracture healing. J Orthop Trauma (2011) 0.94
Creating rigidly stabilized fractures for assessing intramembranous ossification, distraction osteogenesis, or healing of critical sized defects. J Vis Exp (2012) 0.92
Recellularization of aortic valves in pigs. Eur J Cardiothorac Surg (2010) 0.92
Delayed bone regeneration is linked to chronic inflammation in murine muscular dystrophy. J Bone Miner Res (2014) 0.92
MMP9 regulates the cellular response to inflammation after skeletal injury. Bone (2012) 0.91
Fgf8 dosage determines midfacial integration and polarity within the nasal and optic capsules. Dev Biol (2012) 0.91
Mitochondrial T9957C mutation in association with NAION and seizures but not MELAS. Ophthalmic Genet (2005) 0.91
Perioperative antibiotics. J Orthop Res (2014) 0.90
Limitations of standard fluoroscopy in detecting rotational malreduction of the syndesmosis in an ankle fracture model. Foot Ankle Int (2011) 0.90
Recombinant human bone morphogenetic protein-7 enhances fracture healing in an ischemic environment. J Orthop Res (2010) 0.89
Site specific effects of zoledronic acid during tibial and mandibular fracture repair. PLoS One (2012) 0.88
Metamaterial based telemetric strain sensing in different materials. Opt Express (2010) 0.87
Gene therapy for fracture healing. J Orthop Trauma (2010) 0.87
Neural crest cells pattern the surface cephalic ectoderm during FEZ formation. Dev Dyn (2012) 0.87
Evaluation of the embryotoxic potency of compounds in a newly revised high throughput embryonic stem cell test. Toxicol Sci (2008) 0.87
Acute complications of patients with pelvic fractures after pelvic angiographic embolization. Clin Orthop Relat Res (2013) 0.87
Does a volar locking plate provide equivalent stability as a dorsal nonlocking plate in a dorsally comminuted distal radius fracture?: a biomechanical study. J Orthop Trauma (2008) 0.86
Strain and excursion in the rat sciatic nerve during a modified straight leg raise are altered after traumatic nerve injury. J Orthop Res (2005) 0.86
Quantification of shape and cell polarity reveals a novel mechanism underlying malformations resulting from related FGF mutations during facial morphogenesis. Hum Mol Genet (2013) 0.86
Separation of oligonucleotide phosphorothioate diastereoisomers by pellicular anion-exchange chromatography. J Chromatogr A (2010) 0.86
Effect of COX-2 inhibitors and non-steroidal anti-inflammatory drugs on a mouse fracture model. Injury (2006) 0.85