Mechanical stability affects angiogenesis during early fracture healing.

PubWeight™: 0.94‹?›

🔗 View Article (PMC 3167470)

Published in J Orthop Trauma on August 01, 2011

Authors

Chuanyong Lu1, Neema Saless, Diane Hu, Xiaodong Wang, Zhiqing Xing, Huagang Hou, Benjamin Williams, Harold M Swartz, Celine Colnot, Theodore Miclau, Ralph S Marcucio

Author Affiliations

1: Department of Orthopaedic Surgery, Orthopaedic Trauma Institute, San Francisco General Hospital, University of California at San Francisco, San Francisco, CA 94110, USA.

Articles cited by this

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics (2003) 82.89

Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover. Proc Natl Acad Sci U S A (2002) 4.46

Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc Natl Acad Sci U S A (1996) 3.93

Altered fracture repair in the absence of MMP9. Development (2003) 2.41

Shear stress induces spatial reorganization of the endothelial cell cytoskeleton. Cell Motil Cytoskeleton (1998) 2.29

The measurement of oxygen in vivo using EPR techniques. Phys Med Biol (1998) 1.97

Clinical applications of EPR: overview and perspectives. NMR Biomed (2004) 1.93

Prevention of fracture healing in rats by an inhibitor of angiogenesis. Bone (2001) 1.83

A model for intramembranous ossification during fracture healing. J Orthop Res (2002) 1.82

Molecular aspects of healing in stabilized and non-stabilized fractures. J Orthop Res (2001) 1.75

Regulation of osteogenesis-angiogenesis coupling by HIFs and VEGF. J Bone Miner Res (2009) 1.68

Aerobically derived lactate stimulates revascularization and tissue repair via redox mechanisms. Antioxid Redox Signal (2007) 1.45

Activation of the transcription factor HIF-1 and its target genes, VEGF, HO-1, iNOS, during fracture repair. Bone (2004) 1.43

The effect of mechanical stability on local vascularization and tissue differentiation in callus healing. J Orthop Res (2002) 1.37

Ischemia leads to delayed union during fracture healing: a mouse model. J Orthop Res (2007) 1.34

Cyclic, mechanical compression enhances chondrogenesis of mesenchymal progenitor cells in tissue engineering scaffolds. Biorheology (2004) 1.22

Effect of age on vascularization during fracture repair. J Orthop Res (2008) 1.19

Initial vascularization and tissue differentiation are influenced by fixation stability. J Orthop Res (2005) 1.16

Thrombospondin-2 influences the proportion of cartilage and bone during fracture healing. J Bone Miner Res (2009) 1.10

Vascular endothelial growth factor (VEGF)-induced up-regulation of CCN1 in osteoblasts mediates proangiogenic activities in endothelial cells and promotes fracture healing. J Biol Chem (2007) 1.08

Assessing angiogenesis during fracture healing. Iowa Orthop J (2006) 1.04

Novel VEGF family members: VEGF-B, VEGF-C and VEGF-D. Int J Biochem Cell Biol (2001) 1.04

Oxygen sensing and osteogenesis. Ann N Y Acad Sci (2007) 1.04

Effect of shear stress on microvessel network formation of endothelial cells with in vitro three-dimensional model. Am J Physiol Heart Circ Physiol (2004) 1.04

Tibial fracture decreases oxygen levels at the site of injury. Iowa Orthop J (2008) 1.01

The study of rheological effects on vascular endothelial cells in culture. Biorheology (1989) 0.94

The vascular response to fracture micromovement. Clin Orthop Relat Res (1994) 0.93

Hypoxia increases Annexin A2 expression in osteoblastic cells via VEGF and ERK. Bone (2010) 0.90

Articles by these authors

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell (2009) 11.36

R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science (2003) 9.53

The BioGRID Interaction Database: 2011 update. Nucleic Acids Res (2010) 8.46

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis. Cell (2005) 6.86

TNF-alpha induces two distinct caspase-8 activation pathways. Cell (2008) 6.81

Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell (2012) 6.56

Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation. Cell (2005) 6.47

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation. Genes Dev (2003) 6.17

Cytochrome C-mediated apoptosis. Annu Rev Biochem (2004) 5.38

Specific ablation of the apoptotic functions of cytochrome C reveals a differential requirement for cytochrome C and Apaf-1 in apoptosis. Cell (2005) 5.37

WormBase: a comprehensive resource for nematode research. Nucleic Acids Res (2009) 5.20

Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis. Cancer Cell (2007) 5.09

Jaundice Constrain or Indication? Response. Radiology (2017) 5.07

A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death. Science (2004) 4.95

The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell (2012) 4.37

WormBase: new content and better access. Nucleic Acids Res (2006) 4.01

Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy. Int J Radiat Biol (2006) 3.98

WormBase 2012: more genomes, more data, new website. Nucleic Acids Res (2011) 3.87

WormBase 2007. Nucleic Acids Res (2007) 3.69

Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity. Proc Natl Acad Sci U S A (2004) 3.63

Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway. Science (2003) 3.59

Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization. Mol Cell Biol (2007) 3.23

Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation. Mol Cell (2002) 3.06

The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway. Cell (2010) 2.97

Indirect emissions from biofuels: how important? Science (2009) 2.71

Polygenic risk, rapid childhood growth, and the development of obesity: evidence from a 4-decade longitudinal study. Arch Pediatr Adolesc Med (2012) 2.70

Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway. Proc Natl Acad Sci U S A (2011) 2.64

Dietary flavonoids: effects on xenobiotic and carcinogen metabolism. Toxicol In Vitro (2005) 2.60

Altered fracture repair in the absence of MMP9. Development (2003) 2.41

WormBase 2014: new views of curated biology. Nucleic Acids Res (2013) 2.39

Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism. Proc Natl Acad Sci U S A (2007) 2.32

The role of oxygen during fracture healing. Bone (2012) 2.21

Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1. Proc Natl Acad Sci U S A (2005) 2.18

Impact of mouse strain differences in innate hindlimb collateral vasculature. Arterioscler Thromb Vasc Biol (2006) 2.17

Molecular interactions coordinating the development of the forebrain and face. Dev Biol (2005) 2.12

Deciphering the Palimpsest: Studying the Relationship Between Morphological Integration and Phenotypic Covariation. Evol Biol (2009) 2.07

Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK. Proc Natl Acad Sci U S A (2011) 2.06

A longitudinal study of epigenetic variation in twins. Epigenetics (2010) 2.06

A zone of frontonasal ectoderm regulates patterning and growth in the face. Development (2003) 2.04

Hyperparathyroidism and the calcium paradox of aldosteronism. Circulation (2005) 2.03

Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: replication and extension. Arch Gen Psychiatry (2009) 2.01

Cellular basis for age-related changes in fracture repair. J Orthop Res (2005) 1.99

Variability in the assessment of fracture-healing in orthopaedic trauma studies. J Bone Joint Surg Am (2008) 1.97

A SHH-responsive signaling center in the forebrain regulates craniofacial morphogenesis via the facial ectoderm. Development (2008) 1.93

Clinical applications of EPR: overview and perspectives. NMR Biomed (2004) 1.93

Cytochrome P450 2E1 contributes to ethanol-induced fatty liver in mice. Hepatology (2008) 1.90

Serotonin transporter gene moderates childhood maltreatment's effects on persistent but not single-episode depression: replications and implications for resolving inconsistent results. J Affect Disord (2011) 1.84

A model for intramembranous ossification during fracture healing. J Orthop Res (2002) 1.82

Repetitive tissue pO2 measurements by electron paramagnetic resonance oximetry: current status and future potential for experimental and clinical studies. Antioxid Redox Signal (2007) 1.80

HIV/STD prevalence among men who have sex with men in Chengdu, China and associated risk factors for HIV infection. J Acquir Immune Defic Syndr (2010) 1.76

Temporal perturbations in sonic hedgehog signaling elicit the spectrum of holoprosencephaly phenotypes. J Clin Invest (2004) 1.74

Cytokines in alcoholic liver disease. Arch Toxicol (2012) 1.74

Silica encapsulation of n-octadecane via sol-gel process: a novel microencapsulated phase-change material with enhanced thermal conductivity and performance. J Colloid Interface Sci (2009) 1.67

Distinguishing the contributions of the perichondrium, cartilage, and vascular endothelium to skeletal development. Dev Biol (2004) 1.64

Heterotopic ossification in orthopaedic trauma. J Orthop Trauma (2012) 1.63

Generation and characterization of Smac/DIABLO-deficient mice. Mol Cell Biol (2002) 1.61

Hematopoietic stem cells regulate mesenchymal stromal cell induction into osteoblasts thereby participating in the formation of the stem cell niche. Stem Cells (2008) 1.58

A Bayesian connectivity-based approach to constructing probabilistic gene regulatory networks. Bioinformatics (2004) 1.57

Is chronic asthma associated with shorter leukocyte telomere length at midlife? Am J Respir Crit Care Med (2014) 1.55

A structure of the human apoptosome at 12.8 A resolution provides insights into this cell death platform. Structure (2005) 1.53

SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1. Hum Mol Genet (2002) 1.53

Brain monoamine oxidase A activity predicts trait aggression. J Neurosci (2008) 1.51

Autophagy occurs upstream or parallel to the apoptosome during histolytic cell death. Development (2006) 1.50

Quantitative analyses link modulation of sonic hedgehog signaling to continuous variation in facial growth and shape. Development (2010) 1.49

Quantum cascade lasers: 20 years of challenges. Opt Express (2015) 1.48

Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice. Free Radic Biol Med (2010) 1.47

Differentiation of the observed low frequency (1200MHz) EPR signals in whole human teeth. Appl Radiat Isot (2005) 1.47

PHAPI, CAS, and Hsp70 promote apoptosome formation by preventing Apaf-1 aggregation and enhancing nucleotide exchange on Apaf-1. Mol Cell (2008) 1.44

Three-dimensional structure of a double apoptosome formed by the Drosophila Apaf-1 related killer. J Mol Biol (2005) 1.43

In vivo EPR tooth dosimetry for triage after a radiation event involving large populations. Radiat Environ Biophys (2014) 1.42

Overcoming cancer cell resistance to Smac mimetic induced apoptosis by modulating cIAP-2 expression. Proc Natl Acad Sci U S A (2010) 1.42

Structure of an apoptosome-procaspase-9 CARD complex. Structure (2010) 1.42

Interaction with Tap42 is required for the essential function of Sit4 and type 2A phosphatases. Mol Biol Cell (2003) 1.41

Osteopontin, an oxidant stress sensitive cytokine, up-regulates collagen-I via integrin α(V)β(3) engagement and PI3K/pAkt/NFκB signaling. Hepatology (2012) 1.40

The difference in superior adjacent segment pathology after lumbar posterolateral fusion by using 2 different pedicle screw insertion techniques in 9-year minimum follow-up. Spine (Phila Pa 1976) (2014) 1.40

A replicated molecular genetic basis for subtyping antisocial behavior in children with attention-deficit/hyperactivity disorder. Arch Gen Psychiatry (2008) 1.39

Spin traps: in vitro toxicity and stability of radical adducts. Free Radic Biol Med (2003) 1.38

Proposed triage categories for large-scale radiation incidents using high-accuracy biodosimetry methods. Health Phys (2010) 1.38

Polygenic risk and the developmental progression to heavy, persistent smoking and nicotine dependence: evidence from a 4-decade longitudinal study. JAMA Psychiatry (2013) 1.38

Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development. Development (2005) 1.34

Ischemia leads to delayed union during fracture healing: a mouse model. J Orthop Res (2007) 1.34

MERTK receptor tyrosine kinase is a therapeutic target in melanoma. J Clin Invest (2013) 1.34

Dosimetry based on EPR spectral analysis of fingernail clippings. Health Phys (2010) 1.31

Experimental Procedures for Sensitive and Reproducible In Situ EPR Tooth Dosimetry. Radiat Meas (2007) 1.30

Gene clustering based on clusterwide mutual information. J Comput Biol (2004) 1.30

Gene regulatory network reconstruction using conditional mutual information. EURASIP J Bioinform Syst Biol (2008) 1.30

Role of matrix metalloproteinase 13 in both endochondral and intramembranous ossification during skeletal regeneration. PLoS One (2007) 1.29