Published in Protein Expr Purif on March 30, 2005
The synergistic action of accessory enzymes enhances the hydrolytic potential of a "cellulase mixture" but is highly substrate specific. Biotechnol Biofuels (2013) 1.12
Cloning and characterization of a cold-active xylanase enzyme from an environmental DNA library. Extremophiles (2006) 0.99
Expression of endo-1, 4-beta-xylanase from Trichoderma reesei in Pichia pastoris and functional characterization of the produced enzyme. BMC Biotechnol (2009) 0.95
Engineering bifunctional laccase-xylanase chimeras for improved catalytic performance. J Biol Chem (2011) 0.84
Encephalomyocarditis Virus 3C Protease Relieves TRAF Family Member-associated NF-κB Activator (TANK) Inhibitory Effect on TRAF6-mediated NF-κB Signaling through Cleavage of TANK. J Biol Chem (2015) 0.82
High-level secretion of a chimeric thermostable lichenase from Bacillus subtilis by screening of site-mutated signal peptides with structural alterations. Curr Microbiol (2008) 0.80
Introduction of a disulfide bridge enhances the thermostability of a Streptomyces olivaceoviridis xylanase mutant. J Ind Microbiol Biotechnol (2006) 0.79
Amino acid substitutions in the N-terminus, cord and α-helix domains improved the thermostability of a family 11 xylanase XynR8. J Ind Microbiol Biotechnol (2012) 0.78
Insertion of a xylanase in xylose binding protein results in a xylose-stimulated xylanase. Biotechnol Biofuels (2015) 0.77
Seven N-terminal residues of a thermophilic xylanase are sufficient to confer hyperthermostability on its mesophilic counterpart. PLoS One (2014) 0.77
Domain-swapping of mesophilic xylanase with hyper-thermophilic glucanase. BMC Biotechnol (2012) 0.75
A xylose-stimulated xylanase-xylose binding protein chimera created by random nonhomologous recombination. Biotechnol Biofuels (2016) 0.75
High-level expression of improved thermo-stable alkaline xylanase variant in Pichia Pastoris through codon optimization, multiple gene insertion and high-density fermentation. Sci Rep (2016) 0.75
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
Landscape of transcription in human cells. Nature (2012) 20.18
The sex-specific genetic architecture of quantitative traits in humans. Nat Genet (2006) 4.93
Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia. Blood (2008) 4.61
Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. N Engl J Med (2008) 4.58
Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model. J Clin Invest (2008) 4.13
From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene. Proc Natl Acad Sci U S A (2008) 3.39
A role for intestinal endocrine cell-expressed g protein-coupled receptor 119 in glycemic control by enhancing glucagon-like Peptide-1 and glucose-dependent insulinotropic Peptide release. Endocrinology (2008) 3.04
Allele-specific targeting of microRNAs to HLA-G and risk of asthma. Am J Hum Genet (2007) 2.58
Estrogen receptor (ER)-beta reduces ERalpha-regulated gene transcription, supporting a "ying yang" relationship between ERalpha and ERbeta in mice. Mol Endocrinol (2003) 2.38
Linking promoters to functional transcripts in small samples with nanoCAGE and CAGEscan. Nat Methods (2010) 2.30
Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis. Mol Cell Biol (2005) 2.00
A role for beta-cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucose-dependent insulin release. Endocrinology (2007) 1.91
Detection of minimal residual disease in blood and bone marrow in early stage breast cancer. Cancer (2010) 1.90
Preclinical characteristics of the hepatitis C virus NS3/4A protease inhibitor ITMN-191 (R7227). Antimicrob Agents Chemother (2008) 1.56
Characterization of the novel and specific PI3Kα inhibitor NVP-BYL719 and development of the patient stratification strategy for clinical trials. Mol Cancer Ther (2014) 1.56
Differential gene expression associated with migration of mesenchymal stem cells to conditioned medium from tumor cells or bone marrow cells. Stem Cells (2006) 1.56
Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases. Nature (2016) 1.52
Prolonged exposure to reduced levels of androgen accelerates prostate cancer progression in Nkx3.1; Pten mutant mice. Cancer Res (2007) 1.51
Sws1 is a conserved regulator of homologous recombination in eukaryotic cells. EMBO J (2006) 1.46
Epithelial-mesenchymal transition and stem cell markers in patients with HER2-positive metastatic breast cancer. Mol Cancer Ther (2012) 1.44
Long-term renal changes in the liver-specific glucokinase knockout mouse: implications for renal disease in maturity-onset diabetes of the young 2. Transl Res (2010) 1.44
Increased gap density predicts weakness of the epithelial barrier in vivo by confocal laser endomicroscopy in indomethacin-induced enteropathy. Dig Dis Sci (2014) 1.41
Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular inflammation. J Clin Invest (2013) 1.40
Expression of epithelial-mesenchymal transition-inducing transcription factors in primary breast cancer: The effect of neoadjuvant therapy. Int J Cancer (2011) 1.39
Tissue transglutaminase promotes drug resistance and invasion by inducing mesenchymal transition in mammary epithelial cells. PLoS One (2010) 1.36
Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q. J Lipid Res (2009) 1.34
The genome landscape of ERalpha- and ERbeta-binding DNA regions. Proc Natl Acad Sci U S A (2008) 1.27
A caveolae-targeted L-type Ca²+ channel antagonist inhibits hypertrophic signaling without reducing cardiac contractility. Circ Res (2012) 1.26
Cardiotoxic and cardioprotective features of chronic β-adrenergic signaling. Circ Res (2012) 1.20
Genome-wide mapping of estrogen receptor-beta-binding regions reveals extensive cross-talk with transcription factor activator protein-1. Cancer Res (2010) 1.20
Primary breast cancer patients with high risk clinicopathologic features have high percentages of bone marrow epithelial cells with ALDH activity and CD44⁺CD24lo cancer stem cell phenotype. Eur J Cancer (2011) 1.19
Antioxidant and hepatoprotective effects of Schisandra chinensis pollen extract on CCl4-induced acute liver damage in mice. Food Chem Toxicol (2012) 1.19
Treatment with lenalidomide modulates T-cell immunophenotype and cytokine production in patients with chronic lymphocytic leukemia. Cancer (2011) 1.19
RNA interference inhibition of Mus81 reduces mitotic recombination in human cells. Mol Biol Cell (2003) 1.17
Identifying influential nodes in large-scale directed networks: the role of clustering. PLoS One (2013) 1.17
Early clearance of peripheral blood blasts predicts response to induction chemotherapy in acute myeloid leukemia. Cancer (2012) 1.13
Involvement of chronic stresses in rat islet and INS-1 cell glucotoxicity induced by intermittent high glucose. Mol Cell Endocrinol (2008) 1.13
Novel roles of liver X receptors exposed by gene expression profiling in liver and adipose tissue. Mol Pharmacol (2002) 1.12
Analysis of death receptor 5 and caspase-8 expression in primary and metastatic head and neck squamous cell carcinoma and their prognostic impact. PLoS One (2010) 1.11
Breast cancer cells expressing stem cell markers CD44+ CD24 lo are eliminated by Numb-1 peptide-activated T cells. Cancer Immunol Immunother (2008) 1.10
Construction of "small-intelligent" focused mutagenesis libraries using well-designed combinatorial degenerate primers. Biotechniques (2012) 1.07
Sorafenib improves the survival of patients with advanced hepatocellular carcinoma: a meta-analysis of randomized trials. Anticancer Drugs (2010) 1.07
Total anomalous pulmonary venous return involving drainage above, below, and to the heart: a mixed bag. J Am Soc Echocardiogr (2004) 1.07
Rubella virus genotypes in the People's Republic of China between 1979 and 2007: a shift in endemic viruses during the 2001 Rubella Epidemic. J Clin Microbiol (2010) 1.06
Smoothened as a new therapeutic target for human osteosarcoma. Mol Cancer (2010) 1.06
Vitamin D inhibits the formation of prostatic intraepithelial neoplasia in Nkx3.1;Pten mutant mice. Clin Cancer Res (2006) 1.06
Chitosan nanoparticles act as an adjuvant to promote both Th1 and Th2 immune responses induced by ovalbumin in mice. Mar Drugs (2011) 1.04
Ethyl pyruvate protects against hypoxic-ischemic brain injury via anti-cell death and anti-inflammatory mechanisms. Neurobiol Dis (2009) 1.04
Difference in skeletal muscle function in males vs. females: role of estrogen receptor-beta. Am J Physiol Endocrinol Metab (2004) 1.04
Single endemic genotype of measles virus continuously circulating in China for at least 16 years. PLoS One (2012) 1.03
Emergence and continuous evolution of genotype 1E rubella viruses in China. J Clin Microbiol (2011) 1.01
Expression of ezrin correlates with malignant phenotype of lung cancer, and in vitro knockdown of ezrin reverses the aggressive biological behavior of lung cancer cells. Tumour Biol (2012) 1.01
In vitro assessment of cytochrome P450 inhibition: strategies for increasing LC/MS-based assay throughput using a one-point IC(50) method and multiplexing high-performance liquid chromatography. J Pharm Sci (2007) 1.00
Evidence that aberrant expression of tissue transglutaminase promotes stem cell characteristics in mammary epithelial cells. PLoS One (2011) 1.00
Functional characterization of monocarboxylic acid, large neutral amino acid, bile acid and peptide transporters, and P-glycoprotein in MDCK and Caco-2 cells. J Pharm Sci (2002) 1.00
Phosphoglycerate dehydrogenase is dispensable for breast tumor maintenance and growth. Oncotarget (2013) 0.99
The increased range of cervical flexed motion detected by radiographs in Hirayama disease. Eur J Radiol (2010) 0.99
MicroRNA-1 inhibits proliferation of hepatocarcinoma cells by targeting endothelin-1. Life Sci (2012) 0.97
Targeted STIM deletion impairs calcium homeostasis, NFAT activation, and growth of smooth muscle. FASEB J (2012) 0.97
Sevoflurane preconditioning confers neuroprotection via anti-inflammatory effects. Front Biosci (Elite Ed) (2011) 0.97
Lenalidomide induces long-lasting responses in elderly patients with chronic lymphocytic leukemia. Blood (2013) 0.96
Fast evolution of the retroprocessed mitochondrial rps3 gene in Conifer II and further evidence for the phylogeny of gymnosperms. Mol Phylogenet Evol (2009) 0.96
Phase I Dose Escalation Study of Sodium Stibogluconate (SSG), a Protein Tyrosine Phosphatase Inhibitor, Combined with Interferon Alpha for Patients with Solid Tumors. J Cancer (2011) 0.95
Transplantation of human amniotic cells exerts neuroprotection in MPTP-induced Parkinson disease mice. Brain Res (2008) 0.95
MicroRNA profiling links miR-378 to enhanced adipocyte lipolysis in human cancer cachexia. Am J Physiol Endocrinol Metab (2013) 0.95
Prognostic impact of Fas-associated death domain, a key component in death receptor signaling, is dependent on the presence of lymph node metastasis in head and neck squamous cell carcinoma. Cancer Biol Ther (2013) 0.95
Characterizing cancer cells with cancer stem cell-like features in 293T human embryonic kidney cells. Mol Cancer (2010) 0.95
Quasi-molecular fluorescence from graphene oxide. Sci Rep (2011) 0.94
Targeted inhibition of HBV gene expression by single-chain antibody mediated small interfering RNA delivery. Hepatology (2007) 0.94
All-trans retinoic acid promotes neural lineage entry by pluripotent embryonic stem cells via multiple pathways. BMC Cell Biol (2009) 0.94
Increased microRNA-146a levels in plasma of patients with newly diagnosed type 2 diabetes mellitus. PLoS One (2013) 0.94
Melatonin regulates the viability and differentiation of rat midbrain neural stem cells. Cell Mol Neurobiol (2007) 0.93
Synthetic tumor-specific breakpoint peptide vaccine in patients with chronic myeloid leukemia and minimal residual disease: a phase 2 trial. Cancer (2009) 0.93
Utilization of human amniotic mesenchymal cells as feeder layers to sustain propagation of human embryonic stem cells in the undifferentiated state. Cell Reprogram (2011) 0.93
TSC-22 promotes transforming growth factor β-mediated cardiac myofibroblast differentiation by antagonizing Smad7 activity. Mol Cell Biol (2011) 0.92
In vitro effects of chitosan nanoparticles on proliferation of human gastric carcinoma cell line MGC803 cells. World J Gastroenterol (2005) 0.92
Waveguide interrogated optical immunosensor (WIOS) for detection of sulfonamide antibiotics in milk. Biosens Bioelectron (2009) 0.92
Craniofacial morphological characteristics of Chinese adults with normal occlusion and different skeletal divergence. Eur J Orthod (2010) 0.91
{beta}1-Adrenergic receptor activation induces mouse cardiac myocyte death through both L-type calcium channel-dependent and -independent pathways. Am J Physiol Heart Circ Physiol (2010) 0.91
Prognostic Value of EMT-Circulating Tumor Cells in Metastatic Breast Cancer Patients Undergoing High-Dose Chemotherapy with Autologous Hematopoietic Stem Cell Transplantation. J Cancer (2012) 0.91
Magnetic and pH-sensitive nanoparticles for antitumor drug delivery. Colloids Surf B Biointerfaces (2012) 0.91
Comparison of quantum dot technology with conventional immunohistochemistry in examining aldehyde dehydrogenase 1A1 as a potential biomarker for lymph node metastasis of head and neck cancer. Eur J Cancer (2012) 0.91
Sex-specific genetic architecture of asthma-associated quantitative trait loci in a founder population. Curr Allergy Asthma Rep (2006) 0.91
Recombinant human granulocyte-colony-stimulating factor-mobilized and apheresis-collected endothelial progenitor cells: a novel blood cell component for therapeutic vasculogenesis. Transfusion (2006) 0.90
EGFR L861Q mutation is a frequent feature of pulmonary mucoepidermoid carcinoma. J Cancer Res Clin Oncol (2012) 0.90
A surface acoustic wave biosensor concept with low flow cell volumes for label-free detection. Anal Chem (2003) 0.90
Rosiglitazone promotes atherosclerotic plaque stability in fat-fed ApoE-knockout mice. Eur J Pharmacol (2008) 0.90
Anti-tumor effects of atractylenolide I isolated from Atractylodes macrocephala in human lung carcinoma cell lines. Molecules (2013) 0.90
The association between the Pro12Ala variant in the PPARγ2 gene and type 2 diabetes mellitus and obesity in a Chinese population. PLoS One (2013) 0.89
Emodin promotes atherosclerotic plaque stability in fat-fed apolipoprotein E-deficient mice. Tohoku J Exp Med (2008) 0.89
Circulating tumor cells and biomarkers: implications for personalized targeted treatments for metastatic breast cancer. Breast J (2010) 0.89
Estrogen signalling and the metabolic syndrome: targeting the hepatic estrogen receptor alpha action. PLoS One (2013) 0.89
Integrin beta 3 genotype influences asthma and allergy phenotypes in the first 6 years of life. J Allergy Clin Immunol (2007) 0.89
A rare large tracheal glomus tumor with postoperative haematemesis. J Thorac Dis (2013) 0.89
A set of microsatellite primers for Zostera japonica (Zosteraceae). Am J Bot (2011) 0.87
Localization-specific LKB1 loss in head and neck squamous cell carcinoma metastasis. Head Neck (2010) 0.87
A dual-targeting antibody against EGFR-VEGF for lung and head and neck cancer treatment. Int J Cancer (2011) 0.87
The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice. Cancer Cell (2016) 0.87