Published in Hybridoma (Larchmt) on June 01, 2005
Gemcitabine plus carboplatin compared with carboplatin in patients with platinum-sensitive recurrent ovarian cancer: an intergroup trial of the AGO-OVAR, the NCIC CTG, and the EORTC GCG. J Clin Oncol (2006) 4.92
In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis. Biomaterials (2003) 4.26
A randomized clinical trial of cisplatin/paclitaxel versus carboplatin/paclitaxel as first-line treatment of ovarian cancer. J Natl Cancer Inst (2003) 3.77
Nanoshell-enabled photothermal cancer therapy: impending clinical impact. Acc Chem Res (2008) 3.72
Pegylated liposomal Doxorubicin and Carboplatin compared with Paclitaxel and Carboplatin for patients with platinum-sensitive ovarian cancer in late relapse. J Clin Oncol (2010) 3.46
Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives. J Gene Med (2005) 2.71
Progression-specific genes identified by expression profiling of matched ductal carcinomas in situ and invasive breast tumors, combining laser capture microdissection and oligonucleotide microarray analysis. Cancer Res (2006) 2.36
Prospects for cationic polymers in gene and oligonucleotide therapy against cancer. Adv Drug Deliv Rev (2002) 2.27
Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine. J Control Release (2003) 2.18
A cellular Trojan Horse for delivery of therapeutic nanoparticles into tumors. Nano Lett (2007) 2.08
Randomized phase III trial of topotecan following carboplatin and paclitaxel in first-line treatment of advanced ovarian cancer: a gynecologic cancer intergroup trial of the AGO-OVAR and GINECO. J Natl Cancer Inst (2006) 1.86
Chitosan-based formulations for delivery of DNA and siRNA. Adv Drug Deliv Rev (2009) 1.82
Biodistribution of PEG-modified gold nanoparticles following intratracheal instillation and intravenous injection. Biomaterials (2010) 1.77
The effect of dedicated breast surgeons on the short-term outcomes in breast cancer. Ann Surg (2008) 1.72
Polyethylenimine-graft-poly(ethylene glycol) copolymers: influence of copolymer block structure on DNA complexation and biological activities as gene delivery system. Bioconjug Chem (2002) 1.55
Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/SiRNA polyplexes. Bioconjug Chem (2006) 1.55
Phase I study of abagovomab in patients with epithelial ovarian, fallopian tube, or primary peritoneal cancer. Clin Cancer Res (2006) 1.48
The depolymerization of chitosan: effects on physicochemical and biological properties. Int J Pharm (2004) 1.35
Comparative uptake studies of bioadhesive and non-bioadhesive nanoparticles in human intestinal cell lines and rats: the effect of mucus on particle adsorption and transport. Pharm Res (2002) 1.34
Race and ethnicity and breast cancer outcomes in an underinsured population. J Natl Cancer Inst (2010) 1.33
PEGylation of poly(ethylene imine) affects stability of complexes with plasmid DNA under in vivo conditions in a dose-dependent manner after intravenous injection into mice. Bioconjug Chem (2005) 1.32
Integrin targeting using RGD-PEI conjugates for in vitro gene transfer. J Gene Med (2003) 1.30
Mixed-polarization phenotype of ascites-associated macrophages in human ovarian carcinoma: correlation of CD163 expression, cytokine levels and early relapse. Int J Cancer (2013) 1.27
Effect of WOW process parameters on morphology and burst release of FITC-dextran loaded PLGA microspheres. Int J Pharm (2006) 1.27
Safety and immunogenicity of TA-HPV, a recombinant vaccinia virus expressing modified human papillomavirus (HPV)-16 and HPV-18 E6 and E7 genes, in women with progressive cervical cancer. Clin Cancer Res (2002) 1.22
Poly(vinyl alcohol) nanofibers by electrospinning as a protein delivery system and the retardation of enzyme release by additional polymer coatings. Biomacromolecules (2005) 1.22
In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(-PEG)/siRNA complexes. Toxicol Appl Pharmacol (2009) 1.21
Core-cross-linked polymeric micelles as paclitaxel carriers. Bioconjug Chem (2004) 1.20
Potential roles of microRNAs in regulating long intergenic noncoding RNAs. BMC Med Genomics (2013) 1.19
Intracellular processing of poly(ethylene imine)/ribozyme complexes can be observed in living cells by using confocal laser scanning microscopy and inhibitor experiments. Pharm Res (2002) 1.19
Low molecular weight chitosan nanoparticles as new carriers for nasal vaccine delivery in mice. Eur J Pharm Biopharm (2004) 1.18
The Susan G. Komen for the Cure Tissue Bank at the IU Simon Cancer Center: a unique resource for defining the "molecular histology" of the breast. Cancer Prev Res (Phila) (2012) 1.15
Poly(vinyl alcohol)-graft-poly(lactide-co-glycolide) nanoparticles for local delivery of paclitaxel for restenosis treatment. J Control Release (2007) 1.13
Nonviral siRNA delivery to the lung: investigation of PEG-PEI polyplexes and their in vivo performance. Mol Pharm (2009) 1.12
In vivo SPECT and real-time gamma camera imaging of biodistribution and pharmacokinetics of siRNA delivery using an optimized radiolabeling and purification procedure. Bioconjug Chem (2009) 1.12
Star-shaped poly(ethylene glycol)-block-polyethylenimine copolymers enhance DNA condensation of low molecular weight polyethylenimines. Biomacromolecules (2002) 1.11
Biodegradable polymeric nanocarriers for pulmonary drug delivery. Expert Opin Drug Deliv (2008) 1.11
Characterization of a homologous series of D,L-lactic acid oligomers; a mechanistic study on the degradation kinetics in vitro. Biomaterials (2003) 1.10
Toxicity pathway focused gene expression profiling of PEI-based polymers for pulmonary applications. Mol Pharm (2010) 1.10
Do cell culture conditions influence the carrier-mediated transport of peptides in Caco-2 cell monolayers? Eur J Pharm Sci (2003) 1.08
Copolymers of ethylene imine and N-(2-hydroxyethyl)-ethylene imine as tools to study effects of polymer structure on physicochemical and biological properties of DNA complexes. Bioconjug Chem (2002) 1.07
Galactose-PEI-DNA complexes for targeted gene delivery: degree of substitution affects complex size and transfection efficiency. J Control Release (2003) 1.07
Breast cancer proteomics reveals correlation between estrogen receptor status and differential phosphorylation of PGRMC1. Breast Cancer Res (2008) 1.07
The structure of PEG-modified poly(ethylene imines) influences biodistribution and pharmacokinetics of their complexes with NF-kappaB decoy in mice. Pharm Res (2002) 1.06
Crosslinked nanocarriers based upon poly(ethylene imine) for systemic plasmid delivery: in vitro characterization and in vivo studies in mice. J Control Release (2007) 1.05
Triazine dendrimers as nonviral gene delivery systems: effects of molecular structure on biological activity. Bioconjug Chem (2009) 1.03
Pegylated polyethylenimine-Fab' antibody fragment conjugates for targeted gene delivery to human ovarian carcinoma cells. Bioconjug Chem (2003) 1.03
Electrospun biodegradable nanofiber nonwovens for controlled release of proteins. J Control Release (2008) 1.03
Deposition of nanoparticles in the arterial vessel by porous balloon catheters: localization by confocal laser scanning microscopy and transmission electron microscopy. AAPS PharmSci (2002) 1.02
Triazine dendrimers as nonviral vectors for in vitro and in vivo RNAi: the effects of peripheral groups and core structure on biological activity. Mol Pharm (2010) 1.01
Nonviral pulmonary delivery of siRNA. Acc Chem Res (2011) 1.01
Synthesis, characterization and cytotoxicity of poly(ethylene glycol)-graft-trimethyl chitosan block copolymers. Biomaterials (2005) 1.00
Metabolomics approach for predicting response to neoadjuvant chemotherapy for breast cancer. Mol Oncol (2012) 0.99
Self-assembled polyelectrolyte nanocomplexes between chitosan derivatives and insulin. J Pharm Sci (2006) 0.99
Vaccination of patients with advanced ovarian carcinoma with the anti-idiotype ACA125: immunological response and survival (phase Ib/II). Clin Cancer Res (2004) 0.99
Paclitaxel releasing films consisting of poly(vinyl alcohol)-graft-poly(lactide-co-glycolide) and their potential as biodegradable stent coatings. J Control Release (2006) 0.99
Breast cancer proteomics by laser capture microdissection, sample pooling, 54-cm IPG IEF, and differential iodine radioisotope detection. Electrophoresis (2006) 0.98
Effect of poly(ethylene imine) molecular weight and pegylation on organ distribution and pharmacokinetics of polyplexes with oligodeoxynucleotides in mice. Drug Metab Dispos (2004) 0.97
Gene delivery using chitosan, trimethyl chitosan or polyethylenglycol-graft-trimethyl chitosan block copolymers: establishment of structure-activity relationships in vitro. J Control Release (2007) 0.97
Bioreversibly crosslinked polyplexes of PEI and high molecular weight PEG show extended circulation times in vivo. J Control Release (2007) 0.96
Delivery of nanoparticles to brain metastases of breast cancer using a cellular Trojan horse. Cancer Nanotechnol (2012) 0.96
Novel magnetic iron oxide nanoparticles coated with poly(ethylene imine)-g-poly(ethylene glycol) for potential biomedical application: synthesis, stability, cytotoxicity and MR imaging. Int J Pharm (2011) 0.96
Pulmonary drug delivery with aerosolizable nanoparticles in an ex vivo lung model. Int J Pharm (2008) 0.96
Computational insights into the interactions between DNA and siRNA with "rigid" and "flexible" triazine dendrimers. Biomacromolecules (2010) 0.95
Polycationic triazine-based dendrimers: effect of peripheral groups on transfection efficiency. New J Chem (2009) 0.95
Stabilized nanocarriers for plasmids based upon cross-linked poly(ethylene imine). Biomacromolecules (2006) 0.94
Hydrolytic degradation of poly(lactide-co-glycolide) films: effect of oligomers on degradation rate and crystallinity. Int J Pharm (2003) 0.93
In vitro and in vivo complement activation and related anaphylactic effects associated with polyethylenimine and polyethylenimine-graft-poly(ethylene glycol) block copolymers. Biomaterials (2011) 0.93
PEGylation affects cytotoxicity and cell-compatibility of poly(ethylene imine) for lung application: structure-function relationships. Toxicol Appl Pharmacol (2009) 0.92
Targeting the blind spot of polycationic nanocarrier-based siRNA delivery. ACS Nano (2012) 0.92
The potential of glycol chitosan nanoparticles as carrier for low water soluble drugs. Int J Pharm (2009) 0.92
Next-generation transcriptome sequencing of the premenopausal breast epithelium using specimens from a normal human breast tissue bank. Breast Cancer Res (2014) 0.92
Integrin alphaVbeta3 targeted gene delivery using RGD peptidomimetic conjugates with copolymers of PEGylated poly(ethylene imine). Bioconjug Chem (2009) 0.92
Enhancing in vivo circulation and siRNA delivery with biodegradable polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol) copolymers. Biomaterials (2012) 0.92
Amine-modified hyperbranched polyesters as non-toxic, biodegradable gene delivery systems. Biomaterials (2009) 0.92
Physicochemical and biological characterization of polyethylenimine-graft-poly(ethylene glycol) block copolymers as a delivery system for oligonucleotides and ribozymes. Bioconjug Chem (2004) 0.91
Comparative in vivo study of poly(ethylene imine)/siRNA complexes for pulmonary delivery in mice. J Control Release (2011) 0.91
Controlled release of gentamicin from calcium phosphate-poly(lactic acid-co-glycolic acid) composite bone cement. Biomaterials (2006) 0.91
Fast degrading polyesters as siRNA nano-carriers for pulmonary gene therapy. J Control Release (2008) 0.91
Charged nanoparticles as protein delivery systems: a feasibility study using lysozyme as model protein. Eur J Pharm Biopharm (2007) 0.91
Nebulization of biodegradable nanoparticles: impact of nebulizer technology and nanoparticle characteristics on aerosol features. J Control Release (2003) 0.91
Pathologic breast conditions in childhood and adolescence: evaluation by sonographic diagnosis. J Ultrasound Med (2005) 0.90
Peroral delivery of insulin using chitosan derivatives: a comparative study of polyelectrolyte nanocomplexes and nanoparticles. Int J Pharm (2007) 0.90
MMTV-associated transcription factor binding sites increase nm23-H1 metastasis suppressor gene expression in human breast carcinoma cell lines. Clin Exp Metastasis (2002) 0.90
Effect of chitosan structure properties and molecular weight on the intranasal absorption of tetramethylpyrazine phosphate in rats. Eur J Pharm Biopharm (2008) 0.89
CA125 (MUC16) gene silencing suppresses growth properties of ovarian and breast cancer cells. Eur J Cancer (2011) 0.89
The changing landscape of therapeutic strategies for recurrent ovarian cancer. Future Oncol (2012) 0.89
In vitro and in vivo correlation of buserelin release from biodegradable implants using statistical moment analysis. J Control Release (2004) 0.89
Controlled pulmonary drug and gene delivery using polymeric nano-carriers. J Control Release (2011) 0.88
Bioreducible polymers with cell penetrating and endosome buffering functionality for gene delivery systems. J Control Release (2011) 0.88
Cellular uptake mechanism and knockdown activity of siRNA-loaded biodegradable DEAPA-PVA-g-PLGA nanoparticles. Eur J Pharm Biopharm (2011) 0.88
Uptake and transport of PEG-graft-trimethyl-chitosan copolymer-insulin nanocomplexes by epithelial cells. Pharm Res (2005) 0.88
Biophysical investigation of pulmonary surfactant surface properties upon contact with polymeric nanoparticles in vitro. Nanomedicine (2010) 0.88
Effects of cell-penetrating peptides and pegylation on transfection efficiency of polyethylenimine in mouse lungs. J Gene Med (2008) 0.88
Effects of process and formulation parameters on characteristics and internal morphology of poly(d,l-lactide-co-glycolide) microspheres formed by the solvent evaporation method. Eur J Pharm Biopharm (2007) 0.88
DNA nano-carriers from biodegradable cationic branched polyesters are formed by a modified solvent displacement method. J Control Release (2006) 0.87
Breast cancer surgery and angiogenesis: stem cell cycle may explain heterogeneity of recurrence. Int J Surg (2005) 0.87
Biodegradable polymers and their potential use in parenteral veterinary drug delivery systems. Adv Drug Deliv Rev (2004) 0.87