Published in Prog Neuropsychopharmacol Biol Psychiatry on July 01, 2005
Pediatric bipolar disorder: validity, phenomenology, and recommendations for diagnosis. Bipolar Disord (2008) 1.59
The impact of phenotypic and genetic heterogeneity on results of genome wide association studies of complex diseases. PLoS One (2013) 1.51
Antidepressant-like responses to lithium in genetically diverse mouse strains. Genes Brain Behav (2011) 1.01
Molecular actions and clinical pharmacogenetics of lithium therapy. Pharmacol Biochem Behav (2014) 0.94
Lithium in the treatment of bipolar disorder: pharmacology and pharmacogenetics. Mol Psychiatry (2015) 0.94
Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report. PLoS One (2013) 0.88
Neurocognitive functioning in the early stages of bipolar disorder: visual backward masking performance in high risk subjects. Eur Arch Psychiatry Clin Neurosci (2009) 0.88
A genetic network model of cellular responses to lithium treatment and cocaine abuse in bipolar disorder. BMC Syst Biol (2010) 0.83
Interaction networks of lithium and valproate molecular targets reveal a striking enrichment of apoptosis functional clusters and neurotrophin signaling. Pharmacogenomics J (2011) 0.81
BDNF protein levels are decreased in transformed lymphoblasts from lithium-responsive patients with bipolar disorder. J Psychiatry Neurosci (2008) 0.80
Novel integrative genomic tool for interrogating lithium response in bipolar disorder. Transl Psychiatry (2015) 0.79
Effect of the dysbindin gene on antimanic agents in patients with bipolar I disorder. Psychiatry Investig (2008) 0.78
Differential antidepressant-like response to lithium treatment between mouse strains: effects of sex, maternal care, and mixed genetic background. Psychopharmacology (Berl) (2013) 0.77
Pharmacogenomics of mood stabilizers in the treatment of bipolar disorder. Hum Genomics Proteomics (2010) 0.75
Clinical correlates of age at onset distribution in bipolar disorder: a comparison between diagnostic subgroups. Int J Bipolar Disord (2017) 0.75
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci (2009) 10.17
Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature (2010) 9.81
TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis. Nat Genet (2008) 9.51
Variation in genome-wide mutation rates within and between human families. Nat Genet (2011) 8.84
Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines for the management of patients with bipolar disorder: consensus and controversies. Bipolar Disord (2005) 4.94
Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions. Nat Genet (2007) 4.54
International Society for Bipolar Disorders Task Force on Suicide: meta-analyses and meta-regression of correlates of suicide attempts and suicide deaths in bipolar disorder. Bipolar Disord (2014) 4.10
Increased exonic de novo mutation rate in individuals with schizophrenia. Nat Genet (2011) 4.01
Mutations in SYNGAP1 in autosomal nonsyndromic mental retardation. N Engl J Med (2009) 3.88
Direct measure of the de novo mutation rate in autism and schizophrenia cohorts. Am J Hum Genet (2010) 3.69
The developmental trajectory of bipolar disorder. Br J Psychiatry (2013) 3.69
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2009. Bipolar Disord (2009) 3.56
Narcolepsy is strongly associated with the T-cell receptor alpha locus. Nat Genet (2009) 3.33
Course of illness, hippocampal function, and hippocampal volume in major depression. Proc Natl Acad Sci U S A (2003) 3.29
De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia. Proc Natl Acad Sci U S A (2010) 3.13
Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am J Hum Genet (2003) 3.02
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013. Bipolar Disord (2012) 3.01
Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans. Nat Genet (2006) 2.92
Three families with amyotrophic lateral sclerosis and frontotemporal dementia with evidence of linkage to chromosome 9p. Arch Neurol (2007) 2.89
Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disability. Am J Hum Genet (2011) 2.86
Oxidized/misfolded superoxide dismutase-1: the cause of all amyotrophic lateral sclerosis? Ann Neurol (2007) 2.76
Mutation of GABRA1 in an autosomal dominant form of juvenile myoclonic epilepsy. Nat Genet (2002) 2.72
Impaired repression at a 5-hydroxytryptamine 1A receptor gene polymorphism associated with major depression and suicide. J Neurosci (2003) 2.67
Mutations in a gene encoding a novel protein containing a phosphotyrosine-binding domain cause type 2 cerebral cavernous malformations. Am J Hum Genet (2003) 2.58
Risk factors for suicide completion in major depression: a case-control study of impulsive and aggressive behaviors in men. Am J Psychiatry (2005) 2.54
Novel de novo SHANK3 mutation in autistic patients. Am J Med Genet B Neuropsychiatr Genet (2009) 2.43
Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain. PLoS One (2008) 2.40
Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo. Hum Mol Genet (2009) 2.40
Genetics of motor neuron disorders: new insights into pathogenic mechanisms. Nat Rev Genet (2009) 2.31
Exome sequencing identifies FUS mutations as a cause of essential tremor. Am J Hum Genet (2012) 2.30
Mutations in SYNE1 lead to a newly discovered form of autosomal recessive cerebellar ataxia. Nat Genet (2006) 2.17
Common genetic vulnerability to depressive symptoms and coronary artery disease: a review and development of candidate genes related to inflammation and serotonin. Psychosom Med (2006) 2.13
Differential glucocorticoid receptor exon 1(B), 1(C), and 1(H) expression and methylation in suicide completers with a history of childhood abuse. Biol Psychiatry (2012) 2.13
Implication of SSAT by gene expression and genetic variation in suicide and major depression. Arch Gen Psychiatry (2006) 2.13
Genetics of familial and sporadic amyotrophic lateral sclerosis. Biochim Biophys Acta (2006) 2.05
Psychiatric diagnoses in 3275 suicides: a meta-analysis. BMC Psychiatry (2004) 2.02
Bilateral hippocampal volume increase in patients with bipolar disorder and short-term lithium treatment. Neuropsychopharmacology (2007) 2.02
A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura. Nat Med (2010) 2.00
Genetics of familial amyotrophic lateral sclerosis. Neurology (2008) 2.00
Mutations in NHLRC1 cause progressive myoclonus epilepsy. Nat Genet (2003) 2.00
Familial aggregation of suicide explained by cluster B traits: a three-group family study of suicide controlling for major depressive disorder. Am J Psychiatry (2009) 1.95
Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia. Hum Genet (2011) 1.94
Novel RPGR mutations with distinct retinitis pigmentosa phenotypes in French-Canadian families. Am J Ophthalmol (2003) 1.93
Dysfunction of astrocyte connexins 30 and 43 in dorsal lateral prefrontal cortex of suicide completers. Biol Psychiatry (2011) 1.92
Mutations in the KIAA0196 gene at the SPG8 locus cause hereditary spastic paraplegia. Am J Hum Genet (2006) 1.92
Early stages in the development of bipolar disorder. J Affect Disord (2009) 1.88
Risk and resilience markers in bipolar disorder: brain responses to emotional challenge in bipolar patients and their healthy siblings. Am J Psychiatry (2006) 1.84
De novo mutations in FOXP1 in cases with intellectual disability, autism, and language impairment. Am J Hum Genet (2010) 1.79
PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome. Nat Genet (2008) 1.78
Global brain gene expression analysis links glutamatergic and GABAergic alterations to suicide and major depression. PLoS One (2009) 1.78
Disruption at the PTCHD1 Locus on Xp22.11 in Autism spectrum disorder and intellectual disability. Sci Transl Med (2010) 1.75
TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1. Hum Mol Genet (2011) 1.75
Epigenetic regulation of RAC1 induces synaptic remodeling in stress disorders and depression. Nat Med (2013) 1.70
Identification of a novel gene (HSN2) causing hereditary sensory and autonomic neuropathy type II through the Study of Canadian Genetic Isolates. Am J Hum Genet (2004) 1.70
Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. PLoS Genet (2013) 1.68
Four familial ALS pedigrees discordant for two SOD1 mutations: are all SOD1 mutations pathogenic? J Neurol Neurosurg Psychiatry (2010) 1.68
KIF1A, an axonal transporter of synaptic vesicles, is mutated in hereditary sensory and autonomic neuropathy type 2. Am J Hum Genet (2011) 1.66
Mutations in the calcium-related gene IL1RAPL1 are associated with autism. Hum Mol Genet (2008) 1.66
A novel locus for familial amyotrophic lateral sclerosis, on chromosome 18q. Am J Hum Genet (2001) 1.65
Common variants in P2RY11 are associated with narcolepsy. Nat Genet (2010) 1.65
Recent advances in the genetics of amyotrophic lateral sclerosis. Curr Neurol Neurosci Rep (2009) 1.62
Mutations in the nervous system--specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type II. J Clin Invest (2008) 1.61
NLGN3/NLGN4 gene mutations are not responsible for autism in the Quebec population. Am J Med Genet B Neuropsychiatr Genet (2005) 1.60
Risk factors for suicide completion in borderline personality disorder: a case-control study of cluster B comorbidity and impulsive aggression. J Clin Psychiatry (2007) 1.58
The early manifestations of bipolar disorder: a longitudinal prospective study of the offspring of bipolar parents. Bipolar Disord (2007) 1.57
Genome-wide epigenetic regulation by early-life trauma. Arch Gen Psychiatry (2012) 1.57
Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders. Int J Neuropsychopharmacol (2010) 1.56
Diagnosing zygosity in infant twins: physical similarity, genotyping, and chorionicity. Twin Res (2003) 1.56
Sexual orientation and gender identity in youth suicide victims: an exploratory study. Can J Psychiatry (2010) 1.54
The K-Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum. Nat Genet (2002) 1.51
The impact of phenotypic and genetic heterogeneity on results of genome wide association studies of complex diseases. PLoS One (2013) 1.51
Mutations in SYNGAP1 cause intellectual disability, autism, and a specific form of epilepsy by inducing haploinsufficiency. Hum Mutat (2012) 1.50
Psychiatric risk factors for motor vehicle fatalities in young men. Can J Psychiatry (2005) 1.48
Brain structural signature of familial predisposition for bipolar disorder: replicable evidence for involvement of the right inferior frontal gyrus. Biol Psychiatry (2012) 1.47
Oxidative stress markers in bipolar disorder: a meta-analysis. J Affect Disord (2008) 1.46
FUS and TARDBP but not SOD1 interact in genetic models of amyotrophic lateral sclerosis. PLoS Genet (2011) 1.46
A stop codon mutation in SCN9A causes lack of pain sensation. Hum Mol Genet (2007) 1.46
Conserved epigenetic sensitivity to early life experience in the rat and human hippocampus. Proc Natl Acad Sci U S A (2012) 1.45
Epigenetic mechanisms for the early environmental regulation of hippocampal glucocorticoid receptor gene expression in rodents and humans. Neuropsychopharmacology (2012) 1.45
An examination of DSM-IV depressive symptoms and risk for suicide completion in major depressive disorder: a psychological autopsy study. J Affect Disord (2006) 1.44
C9orf72 repeat expansions are a rare genetic cause of parkinsonism. Brain (2013) 1.42
Is violent method of suicide a behavioral marker of lifetime aggression? Am J Psychiatry (2005) 1.42
Impact of comorbid anxiety disorders on outcome in a cohort of patients with bipolar disorder. J Clin Psychiatry (2004) 1.42
De novo STXBP1 mutations in mental retardation and nonsyndromic epilepsy. Ann Neurol (2009) 1.41
Mutations in DCC cause congenital mirror movements. Science (2010) 1.41
Mood disorders--new definitions, treatment directions, and understanding. Can J Psychiatry (2002) 1.40
Stress-induced structural remodeling in hippocampus: prevention by lithium treatment. Proc Natl Acad Sci U S A (2004) 1.37
Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia. Genome Biol (2014) 1.37
Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder. Arch Gen Psychiatry (2010) 1.36
Behavioral and structural responses to chronic cocaine require a feedforward loop involving ΔFosB and calcium/calmodulin-dependent protein kinase II in the nucleus accumbens shell. J Neurosci (2013) 1.35
Genome wide gene expression studies in mood disorders. OMICS (2006) 1.35
Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments. Brain (2011) 1.33
Mutations in C5ORF42 cause Joubert syndrome in the French Canadian population. Am J Hum Genet (2012) 1.32
Alternative splicing, methylation state, and expression profile of tropomyosin-related kinase B in the frontal cortex of suicide completers. Arch Gen Psychiatry (2009) 1.31
A randomized controlled trial of psychoeducation or cognitive-behavioral therapy in bipolar disorder: a Canadian Network for Mood and Anxiety treatments (CANMAT) study [CME]. J Clin Psychiatry (2012) 1.30
Brain-derived neurotrophic factor and inflammatory markers in patients with early- vs. late-stage bipolar disorder. Int J Neuropsychopharmacol (2008) 1.30