Published in Arch Gen Psychiatry on July 01, 2012
Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder. Proc Natl Acad Sci U S A (2013) 1.86
Depression, stress, and anhedonia: toward a synthesis and integrated model. Annu Rev Clin Psychol (2014) 1.85
Predicting Response Trajectories during Cognitive-Behavioural Therapy for Panic Disorder: No Association with the BDNF Gene or Childhood Maltreatment. PLoS One (2016) 1.38
Differences in DNA methylation between human neuronal and glial cells are concentrated in enhancers and non-CpG sites. Nucleic Acids Res (2013) 1.15
Childhood exposure to violence and lifelong health: clinical intervention science and stress-biology research join forces. Dev Psychopathol (2013) 1.14
Epigenetic regulation of the oxytocin receptor gene: implications for behavioral neuroscience. Front Neurosci (2013) 1.08
Cognitive and social lifestyle: links with neuropathology and cognition in late life. Acta Neuropathol (2013) 1.05
Suicide and suicidal behaviour. Lancet (2015) 1.03
DNA methylation signatures triggered by prenatal maternal stress exposure to a natural disaster: Project Ice Storm. PLoS One (2014) 1.02
Epigenetic signaling in psychiatric disorders. J Mol Biol (2014) 1.02
The molecular bases of the suicidal brain. Nat Rev Neurosci (2014) 1.02
Early-life experience, epigenetics, and the developing brain. Neuropsychopharmacology (2014) 1.00
Astrocytic abnormalities and global DNA methylation patterns in depression and suicide. Mol Psychiatry (2014) 0.99
Childhood trauma and adulthood inflammation: a meta-analysis of peripheral C-reactive protein, interleukin-6 and tumour necrosis factor-α. Mol Psychiatry (2015) 0.99
The biological effects of childhood trauma. Child Adolesc Psychiatr Clin N Am (2014) 0.99
DNA methylation and childhood maltreatment: from animal models to human studies. Neuroscience (2013) 0.98
DNA methylation, a hand behind neurodegenerative diseases. Front Aging Neurosci (2013) 0.94
Epigenetic signaling in psychiatric disorders: stress and depression. Dialogues Clin Neurosci (2014) 0.93
Epigenetic modulation of glucocorticoid receptors in posttraumatic stress disorder. Transl Psychiatry (2014) 0.91
A review of hypothalamic-pituitary-adrenal axis function in chronic fatigue syndrome. ISRN Neurosci (2013) 0.91
Epigenomic Mechanisms of Early Adversity and HPA Dysfunction: Considerations for PTSD Research. Front Psychiatry (2013) 0.90
Maternal depression is associated with DNA methylation changes in cord blood T lymphocytes and adult hippocampi. Transl Psychiatry (2015) 0.90
Conserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia. J Neurosci (2013) 0.90
The long-term impact of adverse caregiving environments on epigenetic modifications and telomeres. Front Behav Neurosci (2015) 0.89
Interindividual Variability in Stress Susceptibility: A Role for Epigenetic Mechanisms in PTSD. Front Psychiatry (2013) 0.89
Epigenetic Basis of Mental Illness. Neuroscientist (2015) 0.89
Hippocampal atrophy in major depression: a function of childhood maltreatment rather than diagnosis? Neuropsychopharmacology (2014) 0.88
MORC1 exhibits cross-species differential methylation in association with early life stress as well as genome-wide association with MDD. Transl Psychiatry (2014) 0.88
Pathways Associating Childhood Trauma to the Neurobiology of Schizophrenia. Front Psychol Behav Sci (2014) 0.88
Sensitive periods in epigenetics: bringing us closer to complex behavioral phenotypes. Epigenomics (2012) 0.87
Aberrant regulation of DNA methylation in amyotrophic lateral sclerosis: a new target of disease mechanisms. Neurotherapeutics (2013) 0.86
Bdnf DNA methylation modifications in the hippocampus and amygdala of male and female rats exposed to different caregiving environments outside the homecage. Dev Psychobiol (2014) 0.86
Functional DNA methylation in a transcript specific 3'UTR region of TrkB associates with suicide. Epigenetics (2014) 0.86
Why psychogeriatrics starts right after adolescence. Eur Child Adolesc Psychiatry (2013) 0.86
Early life adversity, genomic plasticity, and psychopathology. Lancet Psychiatry (2014) 0.85
Epigenetic mechanisms in schizophrenia. Dialogues Clin Neurosci (2014) 0.85
Epigenetic alterations in depression and antidepressant treatment. Dialogues Clin Neurosci (2014) 0.85
DNA-methylation gene network dysregulation in peripheral blood lymphocytes of schizophrenia patients. Schizophr Res (2013) 0.85
Epigenetic mechanisms in the development of behavior: advances, challenges, and future promises of a new field. Dev Psychopathol (2013) 0.84
Peripartum depression and anxiety as an integrative cross domain target for psychiatric preventative measures. Behav Brain Res (2014) 0.83
Investigating epigenetic consequences of early-life adversity: some methodological considerations. Eur J Psychotraumatol (2016) 0.83
Epidemiologic evidence for association between adverse environmental exposures in early life and epigenetic variation: a potential link to disease susceptibility? Clin Epigenetics (2015) 0.82
Genome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans. Nat Commun (2016) 0.82
The Influences of Genetic and Environmental Factors on Methylome-wide Association Studies for Human Diseases. Curr Genet Med Rep (2014) 0.82
Epigenomic profiling of men exposed to early-life stress reveals DNA methylation differences in association with current mental state. Transl Psychiatry (2014) 0.82
Estrogen receptor α gene PvuII polymorphism and coronary artery disease: a meta-analysis of 21 studies. J Zhejiang Univ Sci B (2014) 0.81
Interaction between the MTHFR C677T polymorphism and traumatic childhood events predicts depression. Transl Psychiatry (2013) 0.81
A unique gene expression signature associated with serotonin 2C receptor RNA editing in the prefrontal cortex and altered in suicide. Hum Mol Genet (2014) 0.81
Childhood maltreatment and stress-related psychopathology: the epigenetic memory hypothesis. Curr Pharm Des (2015) 0.80
Epigenetic control of mobile DNA as an interface between experience and genome change. Front Genet (2014) 0.79
Association between childhood adversities and long-term suicidality among South Africans from the results of the South African Stress and Health study: a cross-sectional study. BMJ Open (2014) 0.79
Effects of negative stressors on DNA methylation in the brain: implications for mood and anxiety disorders. Am J Med Genet B Neuropsychiatr Genet (2014) 0.79
Epigenetic alterations following early postnatal stress: a review on novel aetiological mechanisms of common psychiatric disorders. Clin Epigenetics (2015) 0.79
Long-term effects of early-life caregiving experiences on brain-derived neurotrophic factor histone acetylation in the adult rat mPFC. Stress (2015) 0.79
The Amsterdam Sexual Abuse Case (ASAC)-study in day care centers: longitudinal effects of sexual abuse on infants and very young children and their parents, and the consequences of the persistence of abusive images on the internet. BMC Psychiatry (2014) 0.78
Evidence from clinical and animal model studies of the long-term and transgenerational impact of stress on DNA methylation. Semin Cell Dev Biol (2015) 0.78
Childhood maltreatment and risk of intimate partner violence: A national study. J Psychiatr Res (2015) 0.78
Role of Inflammation in Suicide: From Mechanisms to Treatment. Neuropsychopharmacology (2016) 0.78
Early-life stress interactions with the epigenome: potential mechanisms driving vulnerability toward psychiatric illness. Behav Pharmacol (2014) 0.77
Epigenetics and suicidal behavior research pathways. Am J Prev Med (2014) 0.77
Antidepressant effects on serotonin 1A/1B receptors in the rat brain using a gene x environment model. Neurosci Lett (2013) 0.77
High cortisol in 5-year-old children causes loss of DNA methylation in SINE retrotransposons: a possible role for ZNF263 in stress-related diseases. Clin Epigenetics (2015) 0.77
Neuroepigenetic Regulation of Pathogenic Memories. Neuroepigenetics (2015) 0.77
Developmental programming modulates olfactory behavior in C. elegans via endogenous RNAi pathways. Elife (2016) 0.77
Glucocorticoids, epigenetic control and stress resilience. Neurobiol Stress (2014) 0.77
Severe psychosocial deprivation in early childhood is associated with increased DNA methylation across a region spanning the transcription start site of CYP2E1. Transl Psychiatry (2016) 0.77
Antecedents and sex/gender differences in youth suicidal behavior. World J Psychiatry (2014) 0.77
Comprehensive interrogation of CpG island methylation in the gene encoding COMT, a key estrogen and catecholamine regulator. BMC Med Genomics (2014) 0.76
A Framework to Examine the Role of Epigenetics in Health Disparities among Native Americans. Nurs Res Pract (2013) 0.76
Animal models to improve our understanding and treatment of suicidal behavior. Transl Psychiatry (2017) 0.76
Serotonin transporter polymorphism (5HTTLPR), severe childhood abuse and depressive symptom trajectories in adulthood. BJPsych Open (2015) 0.75
Understanding epigenetic architecture of suicide neurobiology: A critical perspective. Neurosci Biobehav Rev (2016) 0.75
DNA methylation profiles of elderly individuals subjected to indentured childhood labor and trauma. BMC Med Genet (2017) 0.75
Estrogen receptor alpha polymorphisms, estradiol level, and occurrence of atherosclerosis risk factors in healthy postmenopausal women. Med Sci Monit (2015) 0.75
Tracking the evolution of epialleles during neural differentiation and brain development: D-Aspartate oxidase as a model gene. Epigenetics (2016) 0.75
The neuroepigenetics of suicide. Am J Psychiatry (2013) 0.75
Topical Review: The Emerging Field of Epigenetics: Informing Models of Pediatric Trauma and Physical Health. J Pediatr Psychol (2015) 0.75
Understanding the epigenetic basis of sex differences in depression. J Neurosci Res (2017) 0.75
High-Coverage Whole-Exome Sequencing Identifies Candidate Genes for Suicide in Victims with Major Depressive Disorder. Sci Rep (2017) 0.75
Associations among oxytocin receptor gene (OXTR) DNA methylation in adulthood, exposure to early life adversity, and childhood trajectories of anxiousness. Sci Rep (2017) 0.75
DNA Methylation Profiling of Human Prefrontal Cortex Neurons in Heroin Users Shows Significant Difference between Genomic Contexts of Hyper- and Hypomethylation and a Younger Epigenetic Age. Genes (Basel) (2017) 0.75
Rho GTPases in cell biology. Nature (2002) 22.81
Epigenetic programming by maternal behavior. Nat Neurosci (2004) 20.92
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nat Genet (2005) 15.37
Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci (2006) 13.32
Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat Rev Neurosci (2009) 11.02
NeuN, a neuronal specific nuclear protein in vertebrates. Development (1992) 10.82
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci (2009) 10.17
The guanine nucleotide-binding switch in three dimensions. Science (2001) 9.34
Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci (2000) 9.12
Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications. Nat Biotechnol (2010) 7.00
Childhood adversity and adult psychiatric disorder in the US National Comorbidity Survey. Psychol Med (1997) 5.53
Childhood adversities and adult psychiatric disorders in the national comorbidity survey replication I: associations with first onset of DSM-IV disorders. Arch Gen Psychiatry (2010) 5.53
Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science (2009) 5.24
Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. Neuron (2009) 5.20
Evidence for an instructive mechanism of de novo methylation in cancer cells. Nat Genet (2006) 4.97
DNA methylation profiling of the human major histocompatibility complex: a pilot study for the human epigenome project. PLoS Biol (2004) 4.96
Relationship between multiple forms of childhood maltreatment and adult mental health in community respondents: results from the adverse childhood experiences study. Am J Psychiatry (2003) 4.59
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis. Nat Genet (2001) 4.54
Dynamic DNA methylation programs persistent adverse effects of early-life stress. Nat Neurosci (2009) 4.53
Sexual abuse of boys: definition, prevalence, correlates, sequelae, and management. JAMA (1998) 4.40
Rho GTPases in neuronal morphogenesis. Nat Rev Neurosci (2000) 4.33
A prospective investigation of major depressive disorder and comorbidity in abused and neglected children grown up. Arch Gen Psychiatry (2007) 4.22
Lasting epigenetic influence of early-life adversity on the BDNF gene. Biol Psychiatry (2009) 4.12
Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation. J Neurosci (1997) 4.00
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. Nat Genet (2001) 3.59
Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress. Proc Natl Acad Sci U S A (1998) 3.53
Maternal care, hippocampal synaptogenesis and cognitive development in rats. Nat Neurosci (2000) 3.42
Epigenomics: beyond CpG islands. Nat Rev Genet (2004) 3.21
Chronic fluoxetine stimulates maturation and synaptic plasticity of adult-born hippocampal granule cells. J Neurosci (2008) 3.13
Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine. Proc Natl Acad Sci U S A (2001) 3.01
Maternal care associated with methylation of the estrogen receptor-alpha1b promoter and estrogen receptor-alpha expression in the medial preoptic area of female offspring. Endocrinology (2006) 2.98
The long-term impact of the physical, emotional, and sexual abuse of children: a community study. Child Abuse Negl (1996) 2.97
Childhood adversities and adult psychiatric disorders in the national comorbidity survey replication II: associations with persistence of DSM-IV disorders. Arch Gen Psychiatry (2010) 2.77
Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment. Neuropsychopharmacology (2003) 2.75
Childhood sexual abuse and psychiatric disorder in young adulthood: II. Psychiatric outcomes of childhood sexual abuse. J Am Acad Child Adolesc Psychiatry (1996) 2.65
Antidepressants increase neural progenitor cells in the human hippocampus. Neuropsychopharmacology (2009) 2.63
Maternal care as a model for experience-dependent chromatin plasticity? Trends Neurosci (2005) 2.53
Breaking the neuronal sphere: regulation of the actin cytoskeleton in neuritogenesis. Nat Rev Neurosci (2002) 2.51
Resilience to adult psychopathology following childhood maltreatment: evidence from a community sample. Child Abuse Negl (2007) 2.43
Repeated restraint stress suppresses neurogenesis and induces biphasic PSA-NCAM expression in the adult rat dentate gyrus. Eur J Neurosci (2003) 2.42
Maternal care and hippocampal plasticity: evidence for experience-dependent structural plasticity, altered synaptic functioning, and differential responsiveness to glucocorticoids and stress. J Neurosci (2008) 2.41
Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain. PLoS One (2008) 2.40
Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal. Biol Psychiatry (2008) 2.35
Childhood Experience of Care and Abuse (CECA): a retrospective interview measure. J Child Psychol Psychiatry (1994) 2.09
Genetics of familial and sporadic amyotrophic lateral sclerosis. Biochim Biophys Acta (2006) 2.05
Population attributable fractions of psychiatric disorders and suicide ideation and attempts associated with adverse childhood experiences. Am J Public Health (2008) 1.91
Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice. Nat Neurosci (2010) 1.87
Lower CSF oxytocin concentrations in women with a history of childhood abuse. Mol Psychiatry (2008) 1.82
Exposure to fox odor inhibits cell proliferation in the hippocampus of adult rats via an adrenal hormone-dependent mechanism. J Comp Neurol (2001) 1.79
Running on Ran: nuclear transport and the mitotic spindle. Cell (2001) 1.75
Linkage disequilibrium analysis in young populations: pseudo-vitamin D-deficiency rickets and the founder effect in French Canadians. Am J Hum Genet (1996) 1.68
Acute psychosocial stress reduces cell survival in adult hippocampal neurogenesis without altering proliferation. J Neurosci (2007) 1.58
ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics. Hum Mol Genet (2003) 1.58
Epigenetic modification of hippocampal Bdnf DNA in adult rats in an animal model of post-traumatic stress disorder. J Psychiatr Res (2011) 1.57
Early sexual abuse and lifetime psychopathology: a co-twin-control study. Psychol Med (2000) 1.57
Implications of childhood trauma for depressed women: an analysis of pathways from childhood sexual abuse to deliberate self-harm and revictimization. Am J Psychiatry (2004) 1.52
Maternal care and DNA methylation of a glutamic acid decarboxylase 1 promoter in rat hippocampus. J Neurosci (2010) 1.50
Patterns of gene expression in the limbic system of suicides with and without major depression. Mol Psychiatry (2007) 1.47
Maternal care influences neuronal survival in the hippocampus of the rat. Eur J Neurosci (2003) 1.46
Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress. J Neurosci (2005) 1.43
Is there a specific relationship between childhood sexual and physical abuse and repeated suicidal behavior? Child Abuse Negl (2004) 1.34
Chronic psychosocial stress and concomitant repetitive transcranial magnetic stimulation: effects on stress hormone levels and adult hippocampal neurogenesis. Biol Psychiatry (2002) 1.29
Ageing abolishes the effects of fluoxetine on neurogenesis. Mol Psychiatry (2009) 1.28
Epigenetics and parental effects. Bioessays (2010) 1.28
Neuronal nuclei isolation from human postmortem brain tissue. J Vis Exp (2008) 1.24
Age-dependent effects of chronic stress on brain plasticity and depressive behavior. J Neurochem (2008) 1.24
Diet and the epigenetic (re)programming of phenotypic differences in behavior. Brain Res (2008) 1.22
Als2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities. Proc Natl Acad Sci U S A (2006) 1.21
Signaling the pathway to regeneration. Neuron (2002) 1.21
Genetic risk of depression and stress-induced negative affect in daily life. Br J Psychiatry (2007) 1.20
Blockade of CRF(1) or V(1b) receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression. Mol Psychiatry (2004) 1.16
Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking. J Neurosci (2006) 1.13
Trauma, genes, and the neurobiology of personality disorders. Ann N Y Acad Sci (2004) 1.06
Epigenetics and the biological basis of gene x environment interactions. J Am Acad Child Adolesc Psychiatry (2010) 1.04
Suicidal phenomena and abuse in adolescents: a review of epidemiological studies. Child Abuse Negl (2005) 1.01
Functional implications of decreases in neurogenesis following chronic mild stress in mice. Neuroscience (2007) 0.99
Profiling brain expression of the spermidine/spermine N1-acetyltransferase 1 (SAT1) gene in suicide. Am J Med Genet B Neuropsychiatr Genet (2009) 0.94
ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth. J Biol Chem (2005) 0.94
Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume. Mol Psychiatry (2002) 0.93
Psychosocial processes underlying the maintenance and persistence of depression: implications for understanding chronic depression. Clin Psychol Rev (1999) 0.90
ALS2/alsin deficiency in neurons leads to mild defects in macropinocytosis and axonal growth. Biochem Biophys Res Commun (2008) 0.85
β-catenin promoter ChIP-chip reveals potential schizophrenia and bipolar disorder gene network. J Neurogenet (2010) 0.81
Epigenetic programming by maternal behavior. Nat Neurosci (2004) 20.92
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci (2009) 10.17
Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature (2010) 9.81
Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions. Nat Genet (2007) 4.54
International Society for Bipolar Disorders Task Force on Suicide: meta-analyses and meta-regression of correlates of suicide attempts and suicide deaths in bipolar disorder. Bipolar Disord (2014) 4.10
Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome. Dialogues Clin Neurosci (2005) 3.70
Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life. J Neurosci (2005) 3.48
Socioeconomic status and the brain: mechanistic insights from human and animal research. Nat Rev Neurosci (2010) 3.30
Variations in maternal care in the rat as a mediating influence for the effects of environment on development. Physiol Behav (2003) 3.09
Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood. Proc Natl Acad Sci U S A (2006) 3.07
Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am J Hum Genet (2003) 3.02
Maternal care associated with methylation of the estrogen receptor-alpha1b promoter and estrogen receptor-alpha expression in the medial preoptic area of female offspring. Endocrinology (2006) 2.98
Dopamine release in response to a psychological stress in humans and its relationship to early life maternal care: a positron emission tomography study using [11C]raclopride. J Neurosci (2004) 2.93
Epigenetic mechanisms of perinatal programming of hypothalamic-pituitary-adrenal function and health. Trends Mol Med (2007) 2.92
Glucocorticoid programming. Ann N Y Acad Sci (2004) 2.73
Associations with early-life socio-economic position in adult DNA methylation. Int J Epidemiol (2011) 2.67
Impaired repression at a 5-hydroxytryptamine 1A receptor gene polymorphism associated with major depression and suicide. J Neurosci (2003) 2.67
Risk factors for suicide completion in major depression: a case-control study of impulsive and aggressive behaviors in men. Am J Psychiatry (2005) 2.54
Maternal care as a model for experience-dependent chromatin plasticity? Trends Neurosci (2005) 2.53
Maternal care and hippocampal plasticity: evidence for experience-dependent structural plasticity, altered synaptic functioning, and differential responsiveness to glucocorticoids and stress. J Neurosci (2008) 2.41
Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain. PLoS One (2008) 2.40
Long-term consequences of neonatal rearing on central corticotropin-releasing factor systems in adult male rat offspring. Neuropsychopharmacology (2005) 2.35
The transcription factor nerve growth factor-inducible protein a mediates epigenetic programming: altering epigenetic marks by immediate-early genes. J Neurosci (2007) 2.21
The social environment and the epigenome. Environ Mol Mutagen (2008) 2.18
Epigenetics and the environmental regulation of the genome and its function. Annu Rev Psychol (2010) 2.16
Natural variations in maternal care are associated with estrogen receptor alpha expression and estrogen sensitivity in the medial preoptic area. Endocrinology (2003) 2.15
Implication of SSAT by gene expression and genetic variation in suicide and major depression. Arch Gen Psychiatry (2006) 2.13
Differential glucocorticoid receptor exon 1(B), 1(C), and 1(H) expression and methylation in suicide completers with a history of childhood abuse. Biol Psychiatry (2012) 2.13
Environmental enrichment reverses the effects of maternal separation on stress reactivity. J Neurosci (2002) 2.10
Oxytocin-dopamine interactions mediate variations in maternal behavior in the rat. Endocrinology (2010) 2.09
Homozygous deletion of the very low density lipoprotein receptor gene causes autosomal recessive cerebellar hypoplasia with cerebral gyral simplification. Am J Hum Genet (2005) 2.06
Light at night and melatonin have opposite effects on breast cancer tumors in mice assessed by growth rates and global DNA methylation. Chronobiol Int (2013) 2.05
GABAA receptor promoter hypermethylation in suicide brain: implications for the involvement of epigenetic processes. Biol Psychiatry (2008) 2.04
Deactivation of the limbic system during acute psychosocial stress: evidence from positron emission tomography and functional magnetic resonance imaging studies. Biol Psychiatry (2007) 2.03
Psychiatric diagnoses in 3275 suicides: a meta-analysis. BMC Psychiatry (2004) 2.02
Valproate induces replication-independent active DNA demethylation. J Biol Chem (2003) 2.02
Neurodevelopmental sequelae of postnatal maternal care in rodents: clinical and research implications of molecular insights. J Child Psychol Psychiatry (2007) 2.00
Stress during gestation alters postpartum maternal care and the development of the offspring in a rodent model. Biol Psychiatry (2006) 1.97
Familial aggregation of suicide explained by cluster B traits: a three-group family study of suicide controlling for major depressive disorder. Am J Psychiatry (2009) 1.95
Dysfunction of astrocyte connexins 30 and 43 in dorsal lateral prefrontal cortex of suicide completers. Biol Psychiatry (2011) 1.92
Maternal programming of steroid receptor expression and phenotype through DNA methylation in the rat. Front Neuroendocrinol (2005) 1.87
Broad epigenetic signature of maternal care in the brain of adult rats. PLoS One (2011) 1.86
Epigenetic programming of stress responses through variations in maternal care. Ann N Y Acad Sci (2004) 1.81
Early environmental regulation of hippocampal glucocorticoid receptor gene expression: characterization of intracellular mediators and potential genomic target sites. Ann N Y Acad Sci (2004) 1.80
PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome. Nat Genet (2008) 1.78
Global brain gene expression analysis links glutamatergic and GABAergic alterations to suicide and major depression. PLoS One (2009) 1.78
Transgenerational effects of social environment on variations in maternal care and behavioral response to novelty. Behav Neurosci (2007) 1.76
Variations in nucleus accumbens dopamine associated with individual differences in maternal behavior in the rat. J Neurosci (2004) 1.76
Prenatal maternal depression associates with microstructure of right amygdala in neonates at birth. Biol Psychiatry (2013) 1.75
Stress pathways to spontaneous preterm birth: the role of stressors, psychological distress, and stress hormones. Am J Epidemiol (2009) 1.72
Epigenetic regulation of RAC1 induces synaptic remodeling in stress disorders and depression. Nat Med (2013) 1.70
The programming of individual differences in defensive responses and reproductive strategies in the rat through variations in maternal care. Neurosci Biobehav Rev (2005) 1.62
Definition of the landscape of promoter DNA hypomethylation in liver cancer. Cancer Res (2011) 1.58
Risk factors for suicide completion in borderline personality disorder: a case-control study of cluster B comorbidity and impulsive aggression. J Clin Psychiatry (2007) 1.58
Histone deacetylase inhibitor Trichostatin A induces global and gene-specific DNA demethylation in human cancer cell lines. Biochem Pharmacol (2007) 1.56
Diagnosing zygosity in infant twins: physical similarity, genotyping, and chorionicity. Twin Res (2003) 1.56
Maternal programming of defensive responses through sustained effects on gene expression. Biol Psychol (2006) 1.55
The epigenetics of social adversity in early life: implications for mental health outcomes. Neurobiol Dis (2010) 1.55
Sexual orientation and gender identity in youth suicide victims: an exploratory study. Can J Psychiatry (2010) 1.54
Maternal care influences hippocampal N-methyl-D-aspartate receptor function and dynamic regulation by corticosterone in adulthood. Biol Psychiatry (2012) 1.51
The signature of maternal rearing in the methylome in rhesus macaque prefrontal cortex and T cells. J Neurosci (2012) 1.51
The impact of phenotypic and genetic heterogeneity on results of genome wide association studies of complex diseases. PLoS One (2013) 1.51
Maternal care and DNA methylation of a glutamic acid decarboxylase 1 promoter in rat hippocampus. J Neurosci (2010) 1.50
Psychiatric risk factors for motor vehicle fatalities in young men. Can J Psychiatry (2005) 1.48
Maternal care influences neuronal survival in the hippocampus of the rat. Eur J Neurosci (2003) 1.46
Conserved epigenetic sensitivity to early life experience in the rat and human hippocampus. Proc Natl Acad Sci U S A (2012) 1.45
Epigenetic mechanisms for the early environmental regulation of hippocampal glucocorticoid receptor gene expression in rodents and humans. Neuropsychopharmacology (2012) 1.45
No moderating effect of 5-HTTLPR on associations between antenatal anxiety and infant behavior. J Am Acad Child Adolesc Psychiatry (2013) 1.44
Variations in maternal care alter GABA(A) receptor subunit expression in brain regions associated with fear. Neuropsychopharmacology (2003) 1.44
Maternal care modulates the relationship between prenatal risk and hippocampal volume in women but not in men. J Neurosci (2007) 1.44
An examination of DSM-IV depressive symptoms and risk for suicide completion in major depressive disorder: a psychological autopsy study. J Affect Disord (2006) 1.44
COMT haplotypes modulate associations of antenatal maternal anxiety and neonatal cortical morphology. Am J Psychiatry (2014) 1.43
Is violent method of suicide a behavioral marker of lifetime aggression? Am J Psychiatry (2005) 1.42
Glucocorticoid "programming" and PTSD risk. Ann N Y Acad Sci (2006) 1.39
Maternal programming of sexual behavior and hypothalamic-pituitary-gonadal function in the female rat. PLoS One (2008) 1.39
Valproate induces widespread epigenetic reprogramming which involves demethylation of specific genes. Carcinogenesis (2006) 1.39
Influence of early postnatal rearing conditions on mesocorticolimbic dopamine and behavioural responses to psychostimulants and stressors in adult rats. Eur J Neurosci (2004) 1.39
Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia. Genome Biol (2014) 1.37