| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity.
|
Nat Rev Neurosci
|
2007
|
2.77
|
|
2
|
Mechanisms of recovery from type 2 diabetes after malabsorptive bariatric surgery.
|
Diabetes
|
2006
|
1.89
|
|
3
|
Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6.
|
Diabetes
|
2005
|
1.77
|
|
4
|
Polyunsaturated fatty acids: biochemical, nutritional and epigenetic properties.
|
J Am Coll Nutr
|
2004
|
1.57
|
|
5
|
Bloodletting ameliorates insulin sensitivity and secretion in parallel to reducing liver iron in carriers of HFE gene mutations.
|
Diabetes Care
|
2007
|
1.48
|
|
6
|
Paclitaxel and Cisplatin-induced neurotoxicity: a protective role of acetyl-L-carnitine.
|
Clin Cancer Res
|
2003
|
1.45
|
|
7
|
Insulin clearance in obesity.
|
J Am Coll Nutr
|
2003
|
1.38
|
|
8
|
Acetyl-L-carnitine improves pain, nerve regeneration, and vibratory perception in patients with chronic diabetic neuropathy: an analysis of two randomized placebo-controlled trials.
|
Diabetes Care
|
2005
|
1.35
|
|
9
|
Antioxidant effect of L-carnitine and its short chain esters: relevance for the protection from oxidative stress related cardiovascular damage.
|
Int J Cardiol
|
2006
|
1.30
|
|
10
|
Effects of dietary fatty acids on insulin sensitivity and secretion.
|
Diabetes Obes Metab
|
2004
|
1.21
|
|
11
|
Effect of massive weight loss on inflammatory adipocytokines and the innate immune system in morbidly obese women.
|
J Clin Endocrinol Metab
|
2006
|
1.16
|
|
12
|
Acetylcarnitine induces heme oxygenase in rat astrocytes and protects against oxidative stress: involvement of the transcription factor Nrf2.
|
J Neurosci Res
|
2005
|
1.08
|
|
13
|
Accumulation of overoxidized Peroxiredoxin III in aged rat liver mitochondria.
|
Biochim Biophys Acta
|
2009
|
1.00
|
|
14
|
Proteomics analyses of specific protein oxidation and protein expression in aged rat brain and its modulation by L-acetylcarnitine: insights into the mechanisms of action of this proposed therapeutic agent for CNS disorders associated with oxidative stress.
|
Antioxid Redox Signal
|
2006
|
0.99
|
|
15
|
Carnitine palmitoyltransferase I in human carcinomas: a novel role in histone deacetylation?
|
Cancer Biol Ther
|
2007
|
0.98
|
|
16
|
L-Carnitine: a potential treatment for blocking apoptosis and preventing skeletal muscle myopathy in heart failure.
|
Am J Physiol Cell Physiol
|
2002
|
0.98
|
|
17
|
Acetyl-L-carnitine-induced up-regulation of heat shock proteins protects cortical neurons against amyloid-beta peptide 1-42-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease.
|
J Neurosci Res
|
2006
|
0.97
|
|
18
|
A double-blind, parallel, multicenter comparison of L-acetylcarnitine with placebo on the attention deficit hyperactivity disorder in fragile X syndrome boys.
|
Am J Med Genet A
|
2008
|
0.96
|
|
19
|
Skeletal muscle metabolism in physiology and in cancer disease.
|
J Cell Biochem
|
2003
|
0.95
|
|
20
|
Carnitine-acyltransferase system inhibition, cancer cell death, and prevention of myc-induced lymphomagenesis.
|
J Natl Cancer Inst
|
2013
|
0.95
|
|
21
|
Experimental colitis: decreased Octn2 and Atb0+ expression in rat colonocytes induces carnitine depletion that is reversible by carnitine-loaded liposomes.
|
FASEB J
|
2006
|
0.93
|
|
22
|
Fatty acid synthase hyperactivation in human colorectal cancer: relationship with tumor side and sex.
|
Oncology
|
2007
|
0.92
|
|
23
|
Acetylcarnitine and cellular stress response: roles in nutritional redox homeostasis and regulation of longevity genes.
|
J Nutr Biochem
|
2005
|
0.92
|
|
24
|
Acetyl-L-carnitine protects yeast cells from apoptosis and aging and inhibits mitochondrial fission.
|
Aging Cell
|
2010
|
0.91
|
|
25
|
Neuroprotective effects of acetyl-L-carnitine on neuropathic pain and apoptosis: a role for the nicotinic receptor.
|
J Neurosci Res
|
2009
|
0.91
|
|
26
|
Systemic and brain metabolic dysfunction as a new paradigm for approaching Alzheimer's dementia.
|
Neurochem Res
|
2006
|
0.90
|
|
27
|
Acetyl-L-carnitine: from a biological curiosity to a drug for the peripheral nervous system and beyond.
|
Expert Rev Neurother
|
2013
|
0.90
|
|
28
|
L-carnitine infusions may suppress serum C-reactive protein and improve nutritional status in maintenance hemodialysis patients.
|
J Ren Nutr
|
2005
|
0.88
|
|
29
|
Acetyl-l-carnitine induces muscarinic antinocieption in mice and rats.
|
Neuropharmacology
|
2002
|
0.88
|
|
30
|
Serum levels of fatty acid synthase in colorectal cancer patients are associated with tumor stage.
|
J Gastrointest Cancer
|
2012
|
0.87
|
|
31
|
Carnitine and hemodialysis.
|
Am J Kidney Dis
|
2003
|
0.87
|
|
32
|
Massive weight loss decreases corticosteroid-binding globulin levels and increases free cortisol in healthy obese patients: an adaptive phenomenon?
|
Diabetes Care
|
2007
|
0.86
|
|
33
|
Low 25-hydroxyvitamin D does not affect insulin sensitivity in obesity after bariatric surgery.
|
Obes Res
|
2005
|
0.86
|
|
34
|
Rat liver mitochondrial proteome: changes associated with aging and acetyl-L-carnitine treatment.
|
J Proteomics
|
2011
|
0.86
|
|
35
|
Acetyl-L-carnitine requires phospholipase C-IP3 pathway activation to induce antinociception.
|
Neuropharmacology
|
2004
|
0.85
|
|
36
|
Effect of temperature on the stability of long-chain acylcarnitines in human blood prior to plasma separation.
|
Clin Chim Acta
|
2006
|
0.85
|
|
37
|
The ingestion of saturated fatty acid triacylglycerols acutely affects insulin secretion and insulin sensitivity in human subjects.
|
Br J Nutr
|
2004
|
0.84
|
|
38
|
Progression of cisplatin-induced nephrotoxicity in a carnitine-depleted rat model.
|
Chemotherapy
|
2004
|
0.83
|
|
39
|
Acetyl-L-carnitine protects striatal neurons against in vitro ischemia: the role of endogenous acetylcholine.
|
Neuropharmacology
|
2006
|
0.82
|
|
40
|
History of L-carnitine: implications for renal disease.
|
J Ren Nutr
|
2003
|
0.82
|
|
41
|
Growth hormone and ghrelin secretion in severely obese women before and after bariatric surgery.
|
Obesity (Silver Spring)
|
2007
|
0.82
|
|
42
|
Decreased mitochondrial carnitine translocase in skeletal muscles impairs utilization of fatty acids in insulin-resistant patients.
|
Front Biosci
|
2002
|
0.81
|
|
43
|
Differential carnitine/acylcarnitine translocase expression defines distinct metabolic signatures in skeletal muscle cells.
|
J Cell Physiol
|
2005
|
0.80
|
|
44
|
Protective effect of acetyl-L-carnitine against oxidative stress induced by antiretroviral drugs.
|
FEBS Lett
|
2006
|
0.80
|
|
45
|
Menopause, insulin resistance, and risk factors for cardiovascular disease.
|
Menopause
|
2006
|
0.80
|
|
46
|
Propionyl-L-carnitine reduces intimal hyperplasia after injury in normocholesterolemic rabbit carotid artery by modulating proliferation and caspase 3-dependent apoptosis of vascular smooth muscle cells.
|
Atherosclerosis
|
2002
|
0.79
|
|
47
|
Prolactin and insulin ultradian secretion and adipose tissue lipoprotein lipase expression in severely obese women after bariatric surgery.
|
Obesity (Silver Spring)
|
2008
|
0.79
|
|
48
|
Leptin pulsatility in formerly obese women.
|
FASEB J
|
2005
|
0.79
|
|
49
|
The protective effect of L-carnitine in peripheral blood human lymphocytes exposed to oxidative agents.
|
Mutagenesis
|
2005
|
0.79
|
|
50
|
Carnitine system in uremic patients: molecular and clinical aspects.
|
Semin Nephrol
|
2004
|
0.78
|
|
51
|
Acetyl-L-carnitine up-regulates expression of voltage-dependent anion channel in the rat brain.
|
Neurochem Int
|
2006
|
0.78
|
|
52
|
Identification of differentially expressed genes induced in the rat brain by acetyl-L-carnitine as evidenced by suppression subtractive hybridisation.
|
Brain Res Mol Brain Res
|
2004
|
0.78
|
|
53
|
Ghrelin does not influence gastric emptying in obese subjects.
|
Obes Res
|
2005
|
0.78
|
|
54
|
Muscle unloading potentiates the effects of acetyl-L-carnitine on the slow oxidative muscle phenotype.
|
Biofactors
|
2010
|
0.77
|
|
55
|
Interaction of mildronate with the mitochondrial carnitine/acylcarnitine transport protein.
|
J Biochem Mol Toxicol
|
2008
|
0.77
|
|
56
|
Effects of carnitine on thyroid hormone action.
|
Ann N Y Acad Sci
|
2004
|
0.77
|
|
57
|
Modulatory effect of acetyl-L-carnitine on amyloid precursor protein metabolism in hippocampal neurons.
|
Eur J Pharmacol
|
2008
|
0.77
|
|
58
|
Role of carnitine in modulating acute-phase protein synthesis in hemodialysis patients.
|
J Ren Nutr
|
2005
|
0.77
|
|
59
|
Acetyl-L-carnitine in the management of pain during methadone withdrawal syndrome.
|
Clin Neuropharmacol
|
2009
|
0.76
|
|
60
|
How to consider low serum vitamin D as a risk factor for insulin resistance?
|
Am J Clin Nutr
|
2004
|
0.75
|
|
61
|
Newer aspects of carnitine metabolism in uremia.
|
Semin Nephrol
|
2006
|
0.75
|
|
62
|
Effects of binge eating behavior on fuel oxidation and body composition.
|
J Am Coll Nutr
|
2005
|
0.75
|
|
63
|
Nutritional therapy in chronic kidney disease.
|
Nutr Clin Care
|
2005
|
0.75
|
|
64
|
Histopathologic abnormalities of the lymphoreticular tissues in organic cation transporter 2 deficiency: evidence for impaired B cell maturation.
|
J Pediatr
|
2007
|
0.75
|
|
65
|
Increased formation of short-chain organic acids after chronic ethanol administration and its interaction with the carnitine pool in rat.
|
Arch Biochem Biophys
|
2004
|
0.75
|