Phase I safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas.

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Published in J Clin Oncol on June 13, 2005

Authors

Howard A Burris1, Herbert I Hurwitz, E Claire Dees, Afshin Dowlati, Kimberly L Blackwell, Bert O'Neil, Paul K Marcom, Matthew J Ellis, Beth Overmoyer, Suzanne F Jones, Jennifer L Harris, Deborah A Smith, Kevin M Koch, Andrew Stead, Steve Mangum, Neil L Spector

Author Affiliations

1: The Sarah Cannon Research Institute, 250 25th Avenue N, Suite 110, Nashville, TN 37203, USA. hburris@tnonc.com

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