Published in Br J Cancer on July 11, 2005
Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance. Proc Natl Acad Sci U S A (2011) 1.97
IFN-γ from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer. Br J Cancer (2015) 1.32
Epigenetic determinants of ovarian clear cell carcinoma biology. Int J Cancer (2014) 0.89
Culture models to define key mediators of cancer matrix remodeling. Front Oncol (2014) 0.81
Asian society of gynecologic oncology workshop 2010. J Gynecol Oncol (2010) 0.81
Suppression of ABHD2, identified through a functional genomics screen, causes anoikis resistance, chemoresistance and poor prognosis in ovarian cancer. Oncotarget (2016) 0.76
MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53. Oncotarget (2016) 0.75
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science (1989) 31.55
Extension of life-span by introduction of telomerase into normal human cells. Science (1998) 20.48
Structure and function of telomeres. Nature (1991) 14.82
The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature (1999) 12.60
Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat Genet (1998) 8.91
Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature (1998) 7.81
The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses. J Virol (1996) 6.62
Structure and function of telomeres. Annu Rev Genet (1989) 6.28
PIK3CA is implicated as an oncogene in ovarian cancer. Nat Genet (1999) 6.18
Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas. Int J Cancer (1995) 5.24
Ovarian surface epithelium: biology, endocrinology, and pathology. Endocr Rev (2001) 5.09
p14ARF links the tumour suppressors RB and p53. Nature (1998) 4.78
Abnormal centrosome amplification in the absence of p53. Science (1996) 4.60
Defining the molecular mechanisms of human cell immortalization. Biochim Biophys Acta (1991) 3.73
Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein. Proc Natl Acad Sci U S A (1997) 3.37
WWOX: a candidate tumor suppressor gene involved in multiple tumor types. Proc Natl Acad Sci U S A (2001) 2.79
Inactivation of p16 in human mammary epithelial cells by CpG island methylation. Mol Cell Biol (1998) 2.64
Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors. Cancer Res (1998) 2.07
E-cadherin induces mesenchymal-to-epithelial transition in human ovarian surface epithelium. Proc Natl Acad Sci U S A (1999) 2.05
NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas. Proc Natl Acad Sci U S A (1999) 2.00
The two-stage mechanism controlling cellular senescence and immortalization. Exp Gerontol (1993) 1.98
Clonal heterogeneity in differentiation potential of immortalized human mesenchymal stem cells. Biochem Biophys Res Commun (2002) 1.89
Characterization of cultured human ovarian surface epithelial cells: phenotypic plasticity and premalignant changes. Lab Invest (1994) 1.78
Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers. Gynecol Oncol (2003) 1.75
Human papillomavirus type 16 E7 alleviates a proliferation block in early passage human mammary epithelial cells. Oncogene (1996) 1.71
K-ras activation occurs frequently in mucinous adenocarcinomas and rarely in other common epithelial tumors of the human ovary. Am J Pathol (1991) 1.68
Simian virus 40-transformed human ovarian surface epithelial cells escape normal growth controls but retain morphogenetic responses to extracellular matrix. Am J Obstet Gynecol (1992) 1.62
p16/pRb pathway alterations are required for bypassing senescence in human prostate epithelial cells. Cancer Res (1999) 1.57
Characterization of human ovarian surface epithelial cells immortalized by human papilloma viral oncogenes (HPV-E6E7 ORFs). Exp Cell Res (1995) 1.56
Combination of hTERT and bmi-1, E6, or E7 induces prolongation of the life span of bone marrow stromal cells from an elderly donor without affecting their neurogenic potential. Mol Cell Biol (2005) 1.49
Telomerase prolongs the lifespan of normal human ovarian surface epithelial cells without inducing neoplastic phenotype. J Soc Gynecol Investig (2004) 1.42
Microsatellite instability and alterations in the hMSH2 gene in human ovarian cancer. Int J Cancer (1995) 1.31
Successful immortalization of endometrial glandular cells with normal structural and functional characteristics. Am J Pathol (2003) 1.27
Coexpression of hepatocyte growth factor-Met: an early step in ovarian carcinogenesis? Oncogene (2001) 1.26
Characterization and tumorigenicity of human ovarian surface epithelial cells immortalized by SV40 large T antigen. Gynecol Oncol (2001) 1.26
An ovarian adenocarcinoma line derived from SV40/E-cadherin-transfected normal human ovarian surface epithelium. Int J Cancer (2000) 1.15
Reconstitution of telomerase activity combined with HPV-E7 expression allow human preadipocytes to preserve their differentiation capacity after immortalization. Cell Death Differ (2003) 1.09
Marker profile of mesothelial cells versus ovarian carcinoma cells. Int J Cancer (1989) 0.98
c-myc over-expression in human primary ovarian tumours: its relevance to tumour progression. Int J Cancer (1992) 0.92
Pathophysiological dynamics of human ovarian surface epithelial cells in epithelial ovarian carcinogenesis. Int Rev Cytol (2005) 0.89
The role of the breast cancer susceptibility gene 1 (BRCA1) in sporadic epithelial ovarian cancer. Reprod Biol Endocrinol (2003) 0.86
Roles of luteinizing hormone/chorionic gonadotropin receptor in anchorage-dependent and -independent growth in human ovarian surface epithelial cell lines. Cancer Sci (2003) 0.82
Expression of E-cadherin in human mast cell line HMC-1. APMIS (2003) 0.81
Genetic alterations of the WT1 gene in papillary serous carcinoma of the peritoneum. Gynecol Oncol (2000) 0.80
Isolation, growth and characteristics of human ovarian surface epithelium. Virchows Arch (1994) 0.77
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene. Nature (1990) 8.94
Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme. Science (1997) 5.16
Interleukin-18 regulates both Th1 and Th2 responses. Annu Rev Immunol (2001) 5.02
Defective NK cell activity and Th1 response in IL-18-deficient mice. Immunity (1998) 4.70
Circadian oscillation of a mammalian homologue of the Drosophila period gene. Nature (1997) 4.44
Light-induced resetting of a mammalian circadian clock is associated with rapid induction of the mPer1 transcript. Cell (1997) 3.79
IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production. J Immunol (1998) 3.56
Molecular mechanisms of the biological clock in cultured fibroblasts. Science (2001) 3.46
Role of inorganic polyphosphate in promoting ribosomal protein degradation by the Lon protease in E. coli. Science (2001) 3.35
Cerebral ventriculitis associated with Achromobacter xylosoxidans. J Clin Pathol (1978) 2.86
Thyroplasty as a new phonosurgical technique. Acta Otolaryngol (1975) 2.84
Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein. J Immunol (1996) 2.80
Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu. Cytokine Growth Factor Rev (2001) 2.52
Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT. Mol Cell (1998) 2.44
IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils. Proc Natl Acad Sci U S A (1999) 2.35
Decreased chromate uptake in Pseudomonas fluorescens carrying a chromate resistance plasmid. J Bacteriol (1987) 2.28
Isolation and Characterization of an Enterobacter cloacae Strain That Reduces Hexavalent Chromium under Anaerobic Conditions. Appl Environ Microbiol (1989) 2.23
Interleukin 18 contributes to host resistance and gamma interferon production in mice infected with virulent Salmonella typhimurium. Infect Immun (1999) 2.14
Endotoxin-induced serum factor that stimulates gamma interferon production. Infect Immun (1989) 2.13
Catabolite repression and derepression of arylsulfatase synthesis in Klebsiella aerogenes. J Bacteriol (1974) 2.01
Cloning and expression of the rat prolactin receptor, a member of the growth hormone/prolactin receptor gene family. Cell (1988) 2.00
Dimerization and nuclear entry of mPER proteins in mammalian cells. Genes Dev (2000) 1.98
Buckling of a single microtubule by optical trapping forces: direct measurement of microtubule rigidity. Cell Motil Cytoskeleton (1995) 1.96
IL-18 and IL-12 induce intestinal inflammation and fatty liver in mice in an IFN-gamma dependent manner. Gut (2000) 1.95
A light-independent oscillatory gene mPer3 in mouse SCN and OVLT. EMBO J (1998) 1.92
Interleukin 18 together with interleukin 12 inhibits IgE production by induction of interferon-gamma production from activated B cells. Proc Natl Acad Sci U S A (1997) 1.92
IL-18 induction of IgE: dependence on CD4+ T cells, IL-4 and STAT6. Nat Immunol (2000) 1.86
Isolation and characterization of chemotaxis mutants and genes of Pseudomonas aeruginosa. J Bacteriol (1995) 1.86
IFN-gamma-inducing factor up-regulates Fas ligand-mediated cytotoxic activity of murine natural killer cell clones. J Immunol (1996) 1.85
Antagonistic role of E4BP4 and PAR proteins in the circadian oscillatory mechanism. Genes Dev (2001) 1.82
Distinct role of antigen-specific T helper type 1 (Th1) and Th2 cells in tumor eradication in vivo. J Exp Med (1999) 1.82
Plasmodium berghei infection in mice induces liver injury by an IL-12- and toll-like receptor/myeloid differentiation factor 88-dependent mechanism. J Immunol (2001) 1.82
A new mammalian period gene predominantly expressed in the suprachiasmatic nucleus. Genes Cells (1998) 1.76
The 5' upstream region of mPer1 gene contains two promoters and is responsible for circadian oscillation. Curr Biol (2000) 1.74
IL-18 (IFN-gamma-inducing factor) regulates early cytokine production in, and promotes resolution of, bacterial infection in mice. J Immunol (1998) 1.73
Interleukin-12 (IL-12) and IL-18 synergistically induce the fungicidal activity of murine peritoneal exudate cells against Cryptococcus neoformans through production of gamma interferon by natural killer cells. Infect Immun (1997) 1.71
Caspase-1-independent, Fas/Fas ligand-mediated IL-18 secretion from macrophages causes acute liver injury in mice. Immunity (1999) 1.67
Increased levels of circulating interleukin-18 in patients with advanced tuberculosis. Am J Respir Crit Care Med (2000) 1.65
Forskolin induces circadian gene expression of rPer1, rPer2 and dbp in mammalian rat-1 fibroblasts. FEBS Lett (2000) 1.64
Regulation of tyramine oxidase synthesis in Klebsiella aerogenes. J Bacteriol (1976) 1.62
Lipopolysaccharide-induced IL-18 secretion from murine Kupffer cells independently of myeloid differentiation factor 88 that is critically involved in induction of production of IL-12 and IL-1beta. J Immunol (2001) 1.62
IL-18 accounts for both TNF-alpha- and Fas ligand-mediated hepatotoxic pathways in endotoxin-induced liver injury in mice. J Immunol (1997) 1.62
Neutrophil proteinase 3-mediated induction of bioactive IL-18 secretion by human oral epithelial cells. J Immunol (2001) 1.60
Palmitoylation of p59fyn is reversible and sufficient for plasma membrane association. Mol Biol Cell (1997) 1.59
Propionibacterium acnes treatment diminishes CD4+ NK1.1+ T cells but induces type I T cells in the liver by induction of IL-12 and IL-18 production from Kupffer cells. J Immunol (1997) 1.58
A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma. J Immunol (1997) 1.58
Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells. J Immunol (1999) 1.57
IL-18 protects mice against pulmonary and disseminated infection with Cryptococcus neoformans by inducing IFN-gamma production. J Immunol (1997) 1.55
Genetic control of arylsulfatase synthesis in Klebsiella aerogenes. J Bacteriol (1977) 1.55
Alveolar synechia, ankyloblepharon, and ectodermal disorders: an autosomal recessive disorder? Am J Med Genet (1991) 1.53
Tyramine oxidase and regulation of arylsulfatase synthesis in Klebsiella aerogenes. J Bacteriol (1977) 1.51
hCDC47, a human member of the MCM family. Dissociation of the nucleus-bound form during S phase. J Biol Chem (1996) 1.51
Genetic identification of chemotactic transducers for amino acids in Pseudomonas aeruginosa. Microbiology (1997) 1.50
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Genome Res (2000) 1.50
Interferon-gamma-inducing factor, a novel cytokine, enhances Fas ligand-mediated cytotoxicity of murine T helper 1 cells. Cell Immunol (1996) 1.49
Membrane-associated chromate reductase activity from Enterobacter cloacae. J Bacteriol (1990) 1.48
IL-18 up-regulates perforin-mediated NK activity without increasing perforin messenger RNA expression by binding to constitutively expressed IL-18 receptor. J Immunol (1999) 1.48
Long-term beneficial effect of late reperfusion for acute anterior myocardial infarction with percutaneous transluminal coronary angioplasty. Circulation (1998) 1.47
IL-12 synergizes with IL-18 or IL-1beta for IFN-gamma production from human T cells. Int Immunol (2000) 1.46
Molecular analysis of the phosphate-specific transport (pst) operon of Pseudomonas aeruginosa. Mol Gen Genet (1996) 1.45
Interleukin 18 inhibits osteoclast formation via T cell production of granulocyte macrophage colony-stimulating factor. J Clin Invest (1998) 1.44
Role of DBP in the circadian oscillatory mechanism. Mol Cell Biol (2000) 1.44
Per1 and Per2 gene expression in the rat suprachiasmatic nucleus: circadian profile and the compartment-specific response to light. Neuroscience (1999) 1.44
Cephalometric comparison of craniofacial morphology between primary bone grafted and nongrafted complete unilateral cleft lip and palate adults. Cleft Palate Craniofac J (1996) 1.43
Pathophysiological roles of interleukin-18 in inflammatory liver diseases. Immunol Rev (2000) 1.42
Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD. J Cell Biol (2001) 1.42
Development and validation of the cancer fatigue scale: a brief, three-dimensional, self-rating scale for assessment of fatigue in cancer patients. J Pain Symptom Manage (2000) 1.40
Graft replacement of pararenal inferior vena cava for leiomyosarcoma with the use of venous bypass. Surgery (1993) 1.40
Monoclonal antibodies against the native urease of Helicobacter pylori: synergistic inhibition of urease activity by monoclonal antibody combinations. Infect Immun (1992) 1.40
Postnatal development and sex difference in neurons containing estrogen receptor-alpha immunoreactivity in the preoptic brain, the diencephalon, and the amygdala in the rat. J Comp Neurol (1997) 1.39
A psychosocial group intervention for Japanese women with primary breast carcinoma. Cancer (2000) 1.39
View of a mouse clock gene ticking. Nature (2001) 1.36
Involvement of an extracellular protease in algicidal activity of the marine bacterium Pseudoalteromonas sp. strain A28. Appl Environ Microbiol (2000) 1.36
In vivo interaction of human MCM heterohexameric complexes with chromatin. Possible involvement of ATP. J Biol Chem (1997) 1.35
Prevalence, predictive factors, and screening for psychologic distress in patients with newly diagnosed head and neck cancer. Cancer (2000) 1.35
Cloning, nucleotide sequence, and expression of the chromate resistance determinant of Pseudomonas aeruginosa plasmid pUM505. J Bacteriol (1990) 1.34
Expression of metastasis-related nm23-H1 and nm23-H2 genes in ovarian carcinomas: correlation with clinicopathology, EGFR, c-erbB-2, and c-erbB-3 genes, and sex steroid receptor expression. Cancer Res (1994) 1.32
Immunoregulatory roles of IL-10 in innate immunity: IL-10 inhibits macrophage production of IFN-gamma-inducing factors but enhances NK cell production of IFN-gamma. J Immunol (1998) 1.31
Gonadotrophin-releasing hormone pulse generator activity in the hypothalamus of the goat. J Neuroendocrinol (2009) 1.31
Thyroplasty type I (lateral compression) for dysphonia due to vocal cord paralysis or atrophy. Acta Otolaryngol (1976) 1.31
Production of IL-18 (IFN-gamma-inducing factor) messenger RNA and functional protein by murine keratinocytes. J Immunol (1997) 1.30
Phosphate taxis in Pseudomonas aeruginosa. J Bacteriol (1992) 1.29
IFN-gamma-inducing factor/IL-18 administration mediates IFN-gamma- and IL-12-independent antitumor effects. J Immunol (1998) 1.28
Cloning, sequence and characterization of the polyphosphate kinase-encoding gene (ppk) of Klebsiella aerogenes. Gene (1993) 1.27
Rapid determination of Epstein-Barr virus-specific CD8(+) T-cell frequencies by flow cytometry. Blood (1999) 1.26
Characterization and tumorigenicity of human ovarian surface epithelial cells immortalized by SV40 large T antigen. Gynecol Oncol (2001) 1.26
Solution structure of a telomeric DNA complex of human TRF1. Structure (2001) 1.25
Cloning and characterization of chemotaxis genes in Pseudomonas aeruginosa. Biosci Biotechnol Biochem (1999) 1.24
IL-18 promotes type 1 cytokine production from NK cells and T cells in human intracellular infection. J Immunol (1999) 1.24
Rapid method for analyzing bacterial behavioral responses to chemical stimuli. Appl Environ Microbiol (1992) 1.24
Differential antitumor effects of administration of recombinant IL-18 or recombinant IL-12 are mediated primarily by Fas-Fas ligand- and perforin-induced tumor apoptosis, respectively. J Immunol (1999) 1.22
The costimulatory effect of IL-18 on the induction of antigen-specific IFN-gamma production by resting T cells is IL-12 dependent and is mediated by up-regulation of the IL-12 receptor beta2 subunit. Eur J Immunol (2000) 1.21
Zinc-binding protein in the livers of neonatal, normal and partially hepatectomized rats. Biochem J (1978) 1.21
Two-site interaction of nuclear factor of activated T cells with activated calcineurin. J Biol Chem (1998) 1.20