Published in Cancer Res on June 15, 2005
SPARC: a matricellular regulator of tumorigenesis. J Cell Commun Signal (2009) 1.41
The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion. PLoS One (2012) 1.23
Matricellular proteins: a sticky affair with cancers. J Oncol (2012) 1.10
Bone marrow-derived cathepsin K cleaves SPARC in bone metastasis. Am J Pathol (2009) 1.08
Pathobiology of the neutrophil-intestinal epithelial cell interaction: role in carcinogenesis. World J Gastroenterol (2010) 0.99
SPARC oppositely regulates inflammation and fibrosis in bleomycin-induced lung damage. Am J Pathol (2011) 0.94
Anti-cancer role of SPARC, an inhibitor of adipogenesis. Cancer Treat Rev (2011) 0.93
Tumour cell lines HT-29 and FaDu produce proinflammatory cytokines and activate neutrophils in vitro: possible applications for neutrophil-based antitumour treatment. Mediators Inflamm (2010) 0.88
Matricellular proteins produced by melanocytes and melanomas: in search for functions. Cancer Microenviron (2008) 0.84
Protein profiling of human nonpigmented ciliary epithelium cell secretome: the differentiation factors characterization for retinal ganglion cell line. J Biomed Biotechnol (2011) 0.83
Expression of Secreted Protein Acidic and Rich in Cysteine in the Stroma of a Colorectal Carcinoma is Associated With Patient Prognosis. Ann Coloproctol (2013) 0.82
A survey on the distribution of healthy people with different anti-tumour ability. Arch Med Sci (2010) 0.81
Loss of Sparc in p53-null Astrocytes Promotes Macrophage Activation and Phagocytosis Resulting in Decreased Tumor Size and Tumor Cell Survival. Brain Pathol (2015) 0.78
SPARC Controls Melanoma Cell Plasticity through Rac1. PLoS One (2015) 0.76
Oncolytic Adenovirus-Loaded Menstrual Blood Stem Cells Overcome the Blockade of Viral Activity Exerted by Ovarian Cancer Ascites. Mol Ther Oncolytics (2017) 0.75
Neuronal differentiation in the adult hippocampus recapitulates embryonic development. J Neurosci (2005) 3.98
Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection; A potential mechanism of tumor-immune privilege. Cancer Cell (2004) 2.46
Neurogenic niche modulation by activated microglia: transforming growth factor beta increases neurogenesis in the adult dentate gyrus. Eur J Neurosci (2006) 1.88
Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft. J Invest Dermatol (2007) 1.75
Programmed death (PD)-1:PD-ligand 1/PD-ligand 2 pathway inhibits T cell effector functions during human tuberculosis. J Immunol (2008) 1.67
SPARC endogenous level, rather than fibroblast-produced SPARC or stroma reorganization induced by SPARC, is responsible for melanoma cell growth. J Invest Dermatol (2007) 1.51
Model based analysis of real-time PCR data from DNA binding dye protocols. BMC Bioinformatics (2007) 1.50
The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host. Cancer Metastasis Rev (2008) 1.45
Dendritic cells charged with apoptotic tumor cells induce long-lived protective CD4+ and CD8+ T cell immunity against B16 melanoma. J Immunol (2003) 1.40
Central nervous system injury triggers hepatic CC and CXC chemokine expression that is associated with leukocyte mobilization and recruitment to both the central nervous system and the liver. Am J Pathol (2005) 1.35
Patients beware: commercialized stem cell treatments on the web. Cell Stem Cell (2010) 1.32
Reversible demyelination, blood-brain barrier breakdown, and pronounced neutrophil recruitment induced by chronic IL-1 expression in the brain. Am J Pathol (2004) 1.31
Microglial activation with atypical proinflammatory cytokine expression in a rat model of Parkinson's disease. Eur J Neurosci (2003) 1.30
p21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation. J Cell Sci (2008) 1.24
Therapy with high-dose dexamethasone (HD-DXM) in previously untreated patients affected by idiopathic thrombocytopenic purpura: a GIMEMA experience. Blood (2006) 1.17
Antigen-specific suppression of established arthritis in mice by dendritic cells deficient in NF-kappaB. Arthritis Rheum (2007) 1.10
The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host. Cancer Metastasis Rev (2008) 1.10
Prenatal inflammation impairs adult neurogenesis and memory related behavior through persistent hippocampal TGFβ1 downregulation. Brain Behav Immun (2010) 1.06
Silencing survivin gene expression promotes apoptosis of human breast cancer cells through a caspase-independent pathway. J Cell Biochem (2008) 1.05
A phase I study of an allogeneic cell vaccine (VACCIMEL) with GM-CSF in melanoma patients. J Immunother (2006) 0.99
Overexpression of IL-1beta by adenoviral-mediated gene transfer in the rat brain causes a prolonged hepatic chemokine response, axonal injury and the suppression of spontaneous behaviour. Neurobiol Dis (2007) 0.96
Secretory leukocyte protease inhibitor: a secreted pattern recognition receptor for mycobacteria. Am J Respir Crit Care Med (2008) 0.94
Adenovirus-mediated inhibition of SPARC attenuates liver fibrosis in rats. J Gene Med (2008) 0.94
Interleukin-1β and tumor necrosis factor-α: reliable targets for protective therapies in Parkinson's Disease? Front Cell Neurosci (2013) 0.93
SPARC modulates the proliferation of stromal but not melanoma cells unless endogenous SPARC expression is downregulated. Int J Cancer (2008) 0.93
IL-2- or IL-15-activated NK cells enhance Cetuximab-mediated activity against triple-negative breast cancer in xenografts and in breast cancer patients. Breast Cancer Res Treat (2012) 0.91
A tumor-stroma targeted oncolytic adenovirus replicated in human ovary cancer samples and inhibited growth of disseminated solid tumors in mice. Mol Ther (2012) 0.90
Differential effects of interleukin-1beta on neurotoxicity, cytokine induction and glial reaction in specific brain regions. J Neuroimmunol (2005) 0.90
MART-1- and gp100-expressing and -non-expressing melanoma cells are equally proliferative in tumors and clonogenic in vitro. J Invest Dermatol (2011) 0.89
SPARC promotes cathepsin B-mediated melanoma invasiveness through a collagen I/α2β1 integrin axis. J Invest Dermatol (2011) 0.88
Neutrophil elastase converts human immature dendritic cells into transforming growth factor-beta1-secreting cells and reduces allostimulatory ability. Am J Pathol (2007) 0.88
Migration of polymorphonuclear leucocytes is influenced by dendritic cells. Immunology (2005) 0.88
IL-12 and IL-10 expression synergize to induce the immune-mediated eradication of established colon and mammary tumors and lung metastasis. J Immunol (2005) 0.88
Overexpression of SPARC obliterates the in vivo tumorigenicity of human hepatocellular carcinoma cells. Int J Cancer (2010) 0.87
Therapeutic improvement of a stroma-targeted CRAd by incorporating motives responsive to the melanoma microenvironment. J Invest Dermatol (2013) 0.87
Imbalance of antioxidant enzymes in tumor cells and inhibition of proliferation and malignant features by scavenging hydrogen peroxide. Mol Carcinog (2004) 0.87
Tumor associated stromal cells play a critical role on the outcome of the oncolytic efficacy of conditionally replicative adenoviruses. PLoS One (2008) 0.85
A specific subpopulation of mesenchymal stromal cell carriers overrides melanoma resistance to an oncolytic adenovirus. Stem Cells Dev (2012) 0.85
Gene therapy for autoimmune diseases: quo vadis? Nat Rev Immunol (2004) 0.85
Vaccination with dendritic cells charged with apoptotic/necrotic B16 melanoma induces the formation of subcutaneous lymphoid tissue. Vaccine (2010) 0.84
Pleiotrophin over-expression provides trophic support to dopaminergic neurons in parkinsonian rats. Mol Neurodegener (2011) 0.83
A novel A33 promoter-based conditionally replicative adenovirus suppresses tumor growth and eradicates hepatic metastases in human colon cancer models. Clin Cancer Res (2009) 0.82
Proteomic analysis identified N-cadherin, clusterin, and HSP27 as mediators of SPARC (secreted protein, acidic and rich in cysteines) activity in melanoma cells. Proteomics (2007) 0.82
Anti-tumor effect of SLPI on mammary but not colon tumor growth. J Cell Physiol (2013) 0.82
Suppression of cancer growth by nonviral gene therapy based on a novel reactive oxygen species-responsive promoter. Mol Ther (2009) 0.81
Amyloid peptides ABri and ADan show differential neurotoxicity in transgenic Drosophila models of familial British and Danish dementia. Mol Neurodegener (2014) 0.81
A novel hybrid promoter responsive to pathophysiological and pharmacological regulation. J Mol Med (Berl) (2011) 0.80
Special issue commentary: the changing face of inflammation in the brain. Mol Cell Neurosci (2012) 0.79
The low-abundance transcriptome reveals novel biomarkers, specific intracellular pathways and targetable genes associated with advanced gastric cancer. Int J Cancer (2013) 0.79
Decrease in cAMP levels modulates adhesion to fibronectin and immunostimulatory ability of human dendritic cells. J Leukoc Biol (2002) 0.79
Differential vulnerability of adult neurogenesis by adult and prenatal inflammation: role of TGF-β1. Brain Behav Immun (2013) 0.79
Role of lipids in the early developmental stages of experimental immune diabetes induced by multiple low-dose streptozotocin. J Appl Physiol (1985) (2005) 0.79
Micro-encapsulated secretory leukocyte protease inhibitor decreases cell-mediated immune response in autoimmune orchitis. Life Sci (2011) 0.78
Atheroprotective remodelling of vascular dermatan sulphate proteoglycans in response to hypercholesterolaemia in a rat model. Int J Exp Pathol (2014) 0.77
Identification of a new protective antigen of Bordetella pertussis. Vaccine (2011) 0.77
The multi-reference contrast method: facilitating set enrichment analysis. Comput Biol Med (2012) 0.76
Enhanced CRAd activity using enhancer motifs driven by a nucleosome positioning sequence. Mol Ther (2013) 0.76
Expression of a suicidal gene under control of the human secreted protein acidic and rich in cysteine (SPARC) promoter in tumor or stromal cells led to the inhibition of tumor cell growth. Mol Cancer Ther (2006) 0.76
Platelet-endothelial cell adhesion molecule-1 (CD31) recycles and induces cell growth inhibition on human tumor cell lines. J Cell Biochem (2006) 0.76
Retrospective survey on the prevalence and outcome of prior autoimmune diseases in patients with aplastic anemia reported to the registry of the European group for blood and marrow transplantation. Acta Haematol (2010) 0.75
Improving 2D-DIGE protein expression analysis by two-stage linear mixed models: assessing experimental effects in a melanoma cell study. Bioinformatics (2008) 0.75
SLAM and CD31: signaling molecules involved in cytokine secretion during the development of innate and adaptive immune responses. Cytokine Growth Factor Rev (2007) 0.75
α-Lipoic Acid Protects Against Ischemia-Reperfusion Injury in Simultaneous Kidney-Pancreas Transplantation. Transplantation (2016) 0.75
Evaluation of an indirect enzyme-linked immunosorbent assay for routine screening of Theiler's murine encephalomyelitis virus antibodies in mice colonies. J Vet Diagn Invest (2008) 0.75
CNS response to a second pro-inflammatory event depends on whether the primary demyelinating lesion is active or resolved. Brain Behav Immun (2012) 0.75
[Pasteurella pneumotropica produces regression of human tumors transplanted in immunodeficiency mice]. Medicina (B Aires) (2006) 0.75
Current status of stem cells and regenerative medicine research in Argentina. Stem Cells Dev (2014) 0.75
Immunotherapy with SLPI over-expressing mammary tumor cells decreases tumor growth. Cancer Immunol Immunother (2011) 0.75