Published in J Med Chem on June 30, 2005
The human secretome atlas initiative: implications in health and disease conditions. Biochim Biophys Acta (2013) 0.90
Cytotoxicity and enzymatic activity inhibition in cell lines treated with novel iminosugar derivatives. Glycoconj J (2009) 0.78
Combined arene ruthenium porphyrins as chemotherapeutics and photosensitizers for cancer therapy. J Biol Inorg Chem (2008) 0.76
Synthesis of densely functionalized enantiopure indolizidines by ring-closing metathesis (RCM) of hydroxylamines from carbohydrate-derived nitrones. Beilstein J Org Chem (2007) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
The expression and function of the endothelin system in contractile properties of vaginal myofibroblasts of women with uterovaginal prolapse. Am J Obstet Gynecol (2005) 1.43
Novel 2-[(benzylamino)methyl]pyrrolidine-3,4-diol derivatives as alpha-mannosidase inhibitors and with antitumor activities against hematological and solid malignancies. Bioorg Med Chem (2010) 1.40
Angiotensin II type 2 receptor-mediated vasodilation in human coronary microarteries. Circulation (2004) 1.31
Rational design of indoleamine 2,3-dioxygenase inhibitors. J Med Chem (2010) 1.22
Rational design of platinum(IV) compounds to overcome glutathione-S-transferase mediated drug resistance. J Am Chem Soc (2005) 1.17
Interaction of functionalized superparamagnetic iron oxide nanoparticles with brain structures. J Pharmacol Exp Ther (2006) 1.16
Induction of oxidative stress, lysosome activation and autophagy by nanoparticles in human brain-derived endothelial cells. Biochem J (2012) 1.15
Therapeutic nanoparticles in clinics and under clinical evaluation. Nanomedicine (Lond) (2013) 1.11
Drug combinations with quercetin: doxorubicin plus quercetin in human breast cancer cells. Cancer Chemother Pharmacol (2011) 1.08
5-Aminolevulinic acid derivatives in photomedicine: Characteristics, application and perspectives. Photochem Photobiol (2007) 1.07
Harmonic nanocrystals for biolabeling: a survey of optical properties and biocompatibility. ACS Nano (2012) 1.04
Scavenging free radicals to preserve enhancement and extend relaxation times in NMR using dynamic nuclear polarization. Angew Chem Int Ed Engl (2010) 1.02
Organosulfur compounds: electrophilic reagents in transition-metal-catalyzed carbon-carbon bond-forming reactions. Angew Chem Int Ed Engl (2005) 0.99
Toxicity screenings of nanomaterials: challenges due to interference with assay processes and components of classic in vitro tests. Nanotoxicology (2015) 0.99
Recent synthetic approaches toward non-anomeric spiroketals in natural products. Molecules (2008) 0.97
Surface-functionalized ultrasmall superparamagnetic nanoparticles as magnetic delivery vectors for camptothecin. ChemMedChem (2009) 0.96
Inhibitors of prolyl oligopeptidases for the therapy of human diseases: defining diseases and inhibitors. J Med Chem (2010) 0.93
Silyl methallylsulfinates: efficient and powerful agents for the chemoselective silylation of alcohols, polyols, phenols and carboxylic acids. Chem Commun (Camb) (2005) 0.93
Structural insights into the specificity of Xyn10B from Paenibacillus barcinonensis and its improved stability by forced protein evolution. J Biol Chem (2009) 0.91
Microglial reaction induced by noncytotoxic methylmercury treatment leads to neuroprotection via interactions with astrocytes and IL-6 release. Glia (2002) 0.91
Development of ruthenium antitumor drugs that overcome multidrug resistance mechanisms. J Med Chem (2007) 0.90
Endothelin-converting enzyme-1 inhibition and growth of human glioblastoma cells. J Med Chem (2005) 0.90
Synthesis of the C(1)-C(11) polyene fragment of apoptolidin with a new sulfur dioxide-based organic chemistry. Chemistry (2005) 0.90
Fractional spin-labeling of polymers for enhancing NMR sensitivity by solvent-free dynamic nuclear polarization. Chemphyschem (2011) 0.89
Targeting the endothelin axis in human melanoma: combination of endothelin receptor antagonism and alkylating agents. Exp Biol Med (Maywood) (2006) 0.89
Evaluation of uptake and transport of ultrasmall superparamagnetic iron oxide nanoparticles by human brain-derived endothelial cells. Nanomedicine (Lond) (2012) 0.89
Synthesis and characterization of platinum(IV) anticancer drugs with functionalized aromatic carboxylate ligands: influence of the ligands on drug efficacies and uptake. J Med Chem (2005) 0.89
Virtual screening and computational optimization for the discovery of covalent prolyl oligopeptidase inhibitors with activity in human cells. J Med Chem (2012) 0.87
Rational design of an organometallic glutathione transferase inhibitor. Angew Chem Int Ed Engl (2009) 0.86
Evaluation of docking programs for predicting binding of Golgi alpha-mannosidase II inhibitors: a comparison with crystallography. Proteins (2007) 0.86
N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine. Mol Cancer Ther (2008) 0.86
Ruthenium porphyrin compounds for photodynamic therapy of cancer. J Med Chem (2008) 0.86
Anthracene-tethered ruthenium(II) arene complexes as tools to visualize the cellular localization of putative organometallic anticancer compounds. Inorg Chem (2012) 0.85
Rational design of 4-aryl-1,2,3-triazoles for indoleamine 2,3-dioxygenase 1 inhibition. J Med Chem (2012) 0.85
New efficient route to an advanced precursor of the AB spiroketal of spongistatins. Org Lett (2007) 0.85
Synthesis of novel pyrrolidine 3,4-diol derivatives as inhibitors of alpha-L-fucosidases. Org Biomol Chem (2009) 0.85
Functionalized pyrrolidine inhibitors of human type II alpha-mannosidases as anti-cancer agents: optimizing the fit to the active site. Bioorg Med Chem (2008) 0.85
Inhibitors of tissue-nonspecific alkaline phosphatase: design, synthesis, kinetics, biomineralization and cellular tests. Bioorg Med Chem (2013) 0.84
New synthetic seven-membered 1-azasugars displaying potent inhibition towards glycosidases and glucosylceramide transferase. Chembiochem (2008) 0.84
Scope and limitations of the double [4+3]-cycloadditions of 2-oxyallyl cations to 2,2'-methylenedifuran and derivatives. J Org Chem (2003) 0.84
Structure-activity relationship and multidrug resistance study of new S-trityl-L-cysteine derivatives as inhibitors of Eg5. J Med Chem (2011) 0.84
Thermoresponsive chlorambucil derivatives for tumour targeting. Angew Chem Int Ed Engl (2011) 0.84
Short synthesis of the C16-C28 polyketide fragment of apoptolidin A aglycone. Chem Commun (Camb) (2007) 0.83
Synthesis of chemically functionalized superparamagnetic nanoparticles as delivery vectors for chemotherapeutic drugs. Bioorg Med Chem (2007) 0.83
Molecular imaging by micro-CT: specific E-selectin imaging. Eur Radiol (2009) 0.83
Palladium-catalyzed Stille cross-couplings of sulfonyl chlorides and organostannanes. J Am Chem Soc (2003) 0.82
Studies toward new anti-cancer strategies based on alpha-mannosidase inhibition. Chimia (Aarau) (2010) 0.82
Total synthesis and determination of the absolute configuration of (-)-dolabriferol. Angew Chem Int Ed Engl (2010) 0.82
Evaluation of uptake and transport of cationic and anionic ultrasmall iron oxide nanoparticles by human colon cells. Int J Nanomedicine (2012) 0.82
Glycosylation pathways as drug targets for cancer: glycosidase inhibitors. Mini Rev Med Chem (2006) 0.82
New concise total synthesis of (+)-lentiginosine and some structural analogues. J Org Chem (2005) 0.81
Organometallic ruthenium inhibitors of glutathione-S-transferase P1-1 as anticancer drugs. ChemMedChem (2007) 0.81
In vitro anticancer activity and biologically relevant metabolization of organometallic ruthenium complexes with carbohydrate-based ligands. Chemistry (2008) 0.81
Constrained peptidomimetics reveal detailed geometric requirements of covalent prolyl oligopeptidase inhibitors. J Med Chem (2009) 0.81
Strategy to tether organometallic ruthenium-arene anticancer compounds to recombinant human serum albumin. Inorg Chem (2007) 0.81
Synthesis and conformational analysis of (alpha-D-galactosyl)phenylmethane and alpha-,beta-difluoromethane analogues: interactions with the plant lectin viscumin. Chemistry (2009) 0.81
Organometallic cages as vehicles for intracellular release of photosensitizers. J Am Chem Soc (2011) 0.81
Drug targeting strategies for photodynamic therapy. Anticancer Agents Med Chem (2012) 0.80
A spinning thermometer to monitor microwave heating and glass transitions in dynamic nuclear polarization. Magn Reson Chem (2011) 0.80
Covalent cell surface functionalization of human fetal osteoblasts for tissue engineering. Bioconjug Chem (2011) 0.80
Cell response to the exposure to chitosan-TPP//alginate nanogels. Biomacromolecules (2011) 0.80
Indolobenzazepin-7-ones and 6-, 8-, and 9-membered ring derivatives as tubulin polymerization inhibitors: synthesis and structure--activity relationship studies. J Med Chem (2009) 0.80
Therapeutic potential of endothelin receptor modulators: lessons from human clinical trials. Expert Opin Ther Targets (2009) 0.80
Tumour-derived and host-derived nitric oxide differentially regulate breast carcinoma metastasis to the lungs. Carcinogenesis (2004) 0.80
Tandem Staudinger-azaWittig mediated ring expansion: rapid access to new isofagomine-tetrahydroxyazepane hybrids. Chem Commun (Camb) (2006) 0.79
Evaluation of dipeptide-derivatives of 5-aminolevulinic acid as precursors for photosensitizers in photodynamic therapy. Bioorg Med Chem (2003) 0.79
Glycosidase inhibitors as potential HIV entry inhibitors? Curr Drug Metab (2004) 0.79
Palladium-catalyzed Suzuki-Miyaura cross-couplings of sulfonyl chlorides and boronic acids. Org Lett (2004) 0.79
Interaction of cationic ultrasmall superparamagnetic iron oxide nanoparticles with human melanoma cells. Nanomedicine (Lond) (2010) 0.79
Chitosan-based nanogels for selective delivery of photosensitizers to macrophages and improved retention in and therapy of articular joints. J Control Release (2010) 0.79
Search for alpha-glucosidase inhibitors: new N-substituted valienamine and conduramine F-1 derivatives. Bioorg Med Chem (2006) 0.79
Iron-catalyzed desulfinylative C-C cross-coupling reactions of sulfonyl chlorides with grignard reagents. Angew Chem Int Ed Engl (2008) 0.79
Lack of enantioselectivity in the SULT1A3-catalyzed sulfoconjugation of normetanephrine enantiomers: an in vitro and computational study. Chirality (2012) 0.79
Nucleophilic opening of epoxyazepanes: expanding the family of polyhydroxyazepane-based glycosidase inhibitors. Org Biomol Chem (2006) 0.78
Chemoselective C-H bond activation: ligand and solvent free iron-catalyzed oxidative C-C cross-coupling of tertiary amines with terminal alkynes. Reaction scope and mechanism. Org Lett (2009) 0.78
Transfer of ultrasmall iron oxide nanoparticles from human brain-derived endothelial cells to human glioblastoma cells. ACS Appl Mater Interfaces (2013) 0.78
Cytotoxic effects of combination of oxidosqualene cyclase inhibitors with atorvastatin in human cancer cells. J Med Chem (2012) 0.78
An efficient combinatorial method for the discovery of glycosidase inhibitors. Chembiochem (2002) 0.78
Stereoselective syntheses of 1,4-dideoxy-1,4-imino-octitols and novel tetrahydroxyindolizidines. J Org Chem (2003) 0.78
Total asymmetric synthesis of (-)-conduramine B-1 and of its enantiomer. N-Benzyl derivatives of conduramine B-1 are beta-glucosidase inhibitors. Bioorg Med Chem Lett (2005) 0.78
Design and synthesis of acetamido tri- and tetra-hydroxyazepanes: potent and selective beta-N-acetylhexosaminidase inhibitors. Bioorg Med Chem (2009) 0.78
Deep UV generation and direct DNA photo-interaction by harmonic nanoparticles in labelled samples. Nanoscale (2014) 0.78
A C-linked disaccharide analogue of Thomsen-Friedenreich epitope induces a strong immune response in mice. Chemistry (2012) 0.78
Organometallic anticancer agents that interfere with cellular energy processes: a subtle approach to inducing cancer cell death. Dalton Trans (2012) 0.78
Identification of VKORC1 genotype leading to resistance to tecarfarin. J Clin Pharmacol (2014) 0.77