Published in Nat Rev Drug Discov on July 01, 2005
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Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nat Immunol (2004) 7.22
Substrate-specific activation of sirtuins by resveratrol. J Biol Chem (2005) 5.28
DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science (2002) 4.88
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans. Genes Dev (2004) 4.84
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A requirement for CARMA1 in TCR-induced NF-kappa B activation. Nat Immunol (2002) 3.38
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PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing. J Biol Chem (2002) 3.28
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Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J Med Chem (2005) 2.77
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Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2. J Neurosci (2003) 2.58
Aging networks in Caenorhabditis elegans: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways. Aging Cell (2006) 2.06
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Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice. Regul Pept (2008) 1.05
Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity. J Pharmacol Exp Ther (2011) 0.99
Sarcomeric genes involved in reverse remodeling of the heart during left ventricular assist device support. J Heart Lung Transplant (2005) 0.98
Translating the human microbiome. Nat Biotechnol (2013) 0.90
Human longevity and common variations in the LMNA gene: a meta-analysis. Aging Cell (2012) 0.90
Enhanced gastrointestinal motility with orally active ghrelin receptor agonists. J Pharmacol Exp Ther (2009) 0.85
Microplate filtration assay for nicotinamide release from NAD using a boronic acid resin. Methods (2005) 0.84
Proapoptotic effects of NARC 1 (= PCSK9), the gene encoding a novel serine proteinase. Cytometry A (2006) 0.81