Published in N Engl J Med on July 02, 1992
Cerebrovascular complications of the use of the "crack" form of alkaloidal cocaine. N Engl J Med (1990) 2.23
Standardized endpoint definitions for transcatheter aortic valve implantation clinical trials: a consensus report from the Valve Academic Research Consortium. Eur Heart J (2011) 2.11
Suspected myocardial infarction and left bundle branch block: electrocardiographic indicators of acute ischaemia. J Accid Emerg Med (1999) 1.58
Genetic testing for familial hypertrophic cardiomyopathy in newborn infants. BMJ (1995) 1.44
Fibrinolytic treatment for elderly patients with acute myocardial infarction. Heart (2002) 1.39
Thrombolytic therapy for elderly patients. N Engl J Med (1992) 1.36
A single serum glucose measurement predicts adverse outcomes across the whole range of acute coronary syndromes. Heart (2003) 1.35
Renal function and hyperfiltration capacity in lead smelter workers with high bone lead. Occup Environ Med (1994) 1.18
Prehospital selection of patients for thrombolysis by paramedics. Emerg Med J (2002) 1.07
Thrombolytic therapy for central retinal vein occlusion: results of a pilot study. Trans Am Ophthalmol Soc (1996) 0.97
Myocardial infarction in the elderly. Aging Dis (2010) 0.96
Simplifying thrombolysis decisions in patients with left bundle branch block. Emerg Med J (2005) 0.93
Antithrombotic medication for cardioembolic stroke prevention. Stroke Res Treat (2011) 0.87
Three-dimensional structure of fibrolase, the fibrinolytic enzyme from southern copperhead venom, modeled from the X-ray structure of adamalysin II and atrolysin C. AAPS PharmSci (2001) 0.85
A plea for a more epidemiological and patient-oriented pharmacovigilance. Eur J Clin Pharmacol (2011) 0.82
Immediate and one-year outcome of patients presenting with acute coronary syndrome complicated by stroke: findings from the 2nd Gulf Registry of Acute Coronary Events (Gulf RACE-2). BMC Cardiovasc Disord (2012) 0.80
Primary Angioplasty for the Treatment of Acute ST-Segment Elevated Myocardial Infarction: An Evidence-Based Analysis. Ont Health Technol Assess Ser (2004) 0.79
Anticoagulation after anterior myocardial infarction and the risk of stroke. PLoS One (2010) 0.78
Modified recalcification time (MRT): a sensitive cancer test? Review of the evidence. J Natl Med Assoc (1995) 0.77
Emergency management of acute myocardial infarction. Br J Clin Pharmacol (1999) 0.77
Is 6-month GRACE risk score a useful tool to predict stroke after an acute coronary syndrome? Open Heart (2014) 0.75
The risk of stroke after thrombolytic therapy. N Engl J Med (1992) 0.75
The risk of stroke after thrombolytic therapy. N Engl J Med (1992) 0.75
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med (2001) 20.20
A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. N Engl J Med (2001) 9.75
Effect of prone positioning on the survival of patients with acute respiratory failure. N Engl J Med (2001) 8.74
A trial of goal-oriented hemodynamic therapy in critically ill patients. SvO2 Collaborative Group. N Engl J Med (1995) 7.88
Oxidative DNA damage in peripheral leukocytes of mild cognitive impairment and AD patients. Neurobiol Aging (2005) 4.88
Isolated single coronary artery: a review of 50,000 consecutive coronary angiographies. Eur Heart J (1992) 4.59
Sex, clinical presentation, and outcome in patients with acute coronary syndromes. Global Use of Strategies to Open Occluded Coronary Arteries in Acute Coronary Syndromes IIb Investigators. N Engl J Med (1999) 4.53
Single-bolus tenecteplase compared with front-loaded alteplase in acute myocardial infarction: the ASSENT-2 double-blind randomised trial. Lancet (1999) 4.36
Logistic regression in the medical literature: standards for use and reporting, with particular attention to one medical domain. J Clin Epidemiol (2001) 4.20
Cost effectiveness of early discharge after uncomplicated acute myocardial infarction. N Engl J Med (2000) 4.19
Cost effectiveness of thrombolytic therapy with tissue plasminogen activator as compared with streptokinase for acute myocardial infarction. N Engl J Med (1995) 3.69
The impact of blood glucose self-monitoring on metabolic control and quality of life in type 2 diabetic patients: an urgent need for better educational strategies. Diabetes Care (2001) 3.67
A randomized clinical trial of high-intensity warfarin vs. conventional antithrombotic therapy for the prevention of recurrent thrombosis in patients with the antiphospholipid syndrome (WAPS). J Thromb Haemost (2005) 3.47
Health services: an Italian market. Lancet (1996) 3.43
Predictors of 30-day mortality in the era of reperfusion for acute myocardial infarction. Results from an international trial of 41,021 patients. GUSTO-I Investigators. Circulation (1995) 3.38
Difference in countries' use of resources and clinical outcome for patients with cardiogenic shock after myocardial infarction: results from the GUSTO trial. Lancet (1997) 2.80
Transient symptomatic hypotension in patients on simvastatin. Lancet (1989) 2.67
The threshold for prophylactic platelet transfusions in adults with acute myeloid leukemia. Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto. N Engl J Med (1997) 2.41
Plastic bowing, torus and greenstick supracondylar fractures of the humerus: radiographic clues to obscure fractures of the elbow in children. Radiology (1978) 2.33
Oxidized LDL and malondialdehyde-modified LDL in patients with acute coronary syndromes and stable coronary artery disease. Circulation (1998) 2.32
APOE and Alzheimer disease: a major gene with semi-dominant inheritance. Mol Psychiatry (2011) 2.31
The chaperonin ATPase cycle: mechanism of allosteric switching and movements of substrate-binding domains in GroEL. Cell (1996) 2.28
Estimates of the frequency of chromosome abnormalities detectable in unselected newborns using moderate levels of banding. J Med Genet (1992) 2.27
Relationship between TIMI frame count and clinical outcomes after thrombolytic administration. Thrombolysis In Myocardial Infarction (TIMI) Study Group. Circulation (1999) 2.16
The EMIP project. European Myocardial Infarction Project. Eur Heart J (2000) 2.15
Prognostic value of the admission electrocardiogram in acute coronary syndromes. JAMA (1999) 2.08
Stroke after thrombolysis. Mortality and functional outcomes in the GUSTO-I trial. Global Use of Strategies to Open Occluded Coronary Arteries. Circulation (1995) 2.08
The teaching and organisation of clinical pharmacology in European medical schools (W.H.O. Working Group on Clinical Pharmacology). Eur J Clin Pharmacol (1990) 2.07
One-year results from the Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries (GUSTO-I) trial. GUSTO-I Investigators. Circulation (1996) 2.03
Has clinical pharmacology lost its way? Lancet (1984) 2.02
Clinical pharmacokinetics of diazepam. Clin Pharmacokinet (1978) 1.99
Human pharmacokinetics and bioavailability of temazepam administered in soft gelatin capsules. Eur J Clin Pharmacol (1977) 1.94
Coronary artery fistulas in an adult population. Eur Heart J (1986) 1.92
Time from symptom onset to treatment and outcomes after thrombolytic therapy. GUSTO-1 Investigators. J Am Coll Cardiol (1996) 1.91
Circulating oxidized LDL is a useful marker for identifying patients with coronary artery disease. Arterioscler Thromb Vasc Biol (2001) 1.89
"Pap" smear and the risk of cervical neoplasia: quantitative estimates from a case-control study. Lancet (1984) 1.87
Interpretation of automated perimetry for glaucoma by neural network. Invest Ophthalmol Vis Sci (1994) 1.86
Abciximab facilitates the rate and extent of thrombolysis: results of the thrombolysis in myocardial infarction (TIMI) 14 trial. The TIMI 14 Investigators. Circulation (1999) 1.83
Age-related increase in mortality among patients with first myocardial infarctions treated with thrombolysis. The Investigators of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI-2). N Engl J Med (1993) 1.81
ACE inhibitor use in patients with myocardial infarction. Summary of evidence from clinical trials. Circulation (1995) 1.75
North-South twinning in paediatric haemato-oncology: the La Mascota programme, Nicaragua. Lancet (1998) 1.75
Prevalence and prognostic significance of ventricular arrhythmias after acute myocardial infarction in the fibrinolytic era. GISSI-2 results. Circulation (1993) 1.74
Improved reliability of lymphoma diagnostics via PCR-based clonality testing: report of the BIOMED-2 Concerted Action BHM4-CT98-3936. Leukemia (2006) 1.72
Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors. J Biol Chem (2001) 1.72
Is the current classification of venous thromboembolism acceptable? No. J Thromb Haemost (2004) 1.70
The cervical aortic arch. Am J Roentgenol Radium Ther Nucl Med (1975) 1.68
Bile duct injuries during laparoscopic cholecystectomy: a 1994-2001 audit on 13,718 operations in the area of Rome. Surg Endosc (2003) 1.68
Effect of the ACE inhibitor lisinopril on mortality in diabetic patients with acute myocardial infarction: data from the GISSI-3 study. Circulation (1997) 1.68
Nicotine treatment of mild cognitive impairment: a 6-month double-blind pilot clinical trial. Neurology (2012) 1.67
Assessment of absolute risk of death after myocardial infarction by use of multiple-risk-factor assessment equations: GISSI-Prevenzione mortality risk chart. Eur Heart J (2001) 1.66
Feasibility of a large prospective study in general practice: an Italian experience. Gruppo di Studio sulla Pressione Arteriosa nell'Anziano. Br Med J (Clin Res Ed) (1987) 1.65
Oestrogens and obesity as risk factors for endometrial cancer in Italy. Int J Epidemiol (1982) 1.64
Pharmacokinetics of N-demethyldiazepam in patients suffering from insomnia and treated with nortriptyline. Br J Clin Pharmacol (1975) 1.63
Powerful strategy for polymerase chain reaction-based clonality assessment in T-cell malignancies Report of the BIOMED-2 Concerted Action BHM4 CT98-3936. Leukemia (2006) 1.62
Enhanced Ca(2+) release and Na/Ca exchange activity in hypertrophied canine ventricular myocytes: potential link between contractile adaptation and arrhythmogenesis. Circulation (2000) 1.61
Misconceptions about cholesterol. N Z Med J (1990) 1.60
Creatine kinase-MB elevation after percutaneous coronary intervention predicts adverse outcomes in patients with acute coronary syndromes. Eur Heart J (2004) 1.59
Self-monitoring of blood glucose in non-insulin-treated diabetic patients: a longitudinal evaluation of its impact on metabolic control. Diabet Med (2005) 1.59
Coronary thrombolysis with tissue-type plasminogen activator in patients with evolving myocardial infarction. N Engl J Med (1984) 1.57
Epidemiology of post-infarction risk stratification strategies in a country with a low volume of revascularization procedures. GISSI-Prognosis Investigators. Eur Heart J (1998) 1.56
Risk factors for myocardial infarction in young women. Am J Epidemiol (1987) 1.55
Clinicopathological features and prognosis of gastric cancer in young European adults. Br J Surg (2007) 1.55
N-desmethyldiazepam and amylobarbitone sodium as hypnotics in anxious patients. Plasma levels, clinical efficacy and residual effects. Psychopharmacologia (1975) 1.54
Fibrils from brains of cows with new cattle disease contain scrapie-associated protein. Nature (1988) 1.54
Short- and long-term outcomes following atrial fibrillation in patients with acute coronary syndromes with or without ST-segment elevation. Heart (2008) 1.54
Clinical pharmacokinetics of amiodarone. Clin Pharmacokinet (1984) 1.53
Acute coronary syndromes in the GUSTO-IIb trial: prognostic insights and impact of recurrent ischemia. The GUSTO-IIb Investigators. Circulation (1998) 1.52
Incessant ovulation and ovarian cancer: a critical approach. Int J Epidemiol (1983) 1.51
Injuries of the medial epicondylar ossification center of the humerus. AJR Am J Roentgenol (1977) 1.51
Osteoporosis and osteopenia in adults and adolescents with cystic fibrosis: prevalence and associated factors. Thorax (2000) 1.51
Effect of early intravenous heparin on coronary patency, infarct size, and bleeding complications after alteplase thrombolysis: results of a randomised double blind European Cooperative Study Group trial. Br Heart J (1992) 1.50
High frame rate myocardial integrated backscatter. Does this change our understanding of this acoustic parameter? Eur J Echocardiogr (2000) 1.49
Second-generation clinical pharmacology. Lancet (1986) 1.49
Strain differences in susceptibility to murine respiratory mycoplasmosis in C57BL/6 and C3H/HeN mice. Infect Immun (1985) 1.49
Development of an aerosol model of murine respiratory mycoplasmosis in mice. Infect Immun (1986) 1.48
Inhibition of complement activation by pexelizumab reduces death in patients undergoing combined aortic valve replacement and coronary artery bypass surgery. J Thorac Cardiovasc Surg (2006) 1.48
The long-term prognostic significance of repeated blood pressure measurements in the elderly: SPAA (Studio sulla Pressione Arteriosa nell'Anziano) 10-year follow-up. Arch Intern Med (1999) 1.48
Expression of c-kit receptor in normal and transformed human nonlymphoid tissues. Cancer Res (1992) 1.47
Effect of superoxide dismutase on infarct size and postischemic recovery of myocardial contractility and metabolism in dogs. J Am Coll Cardiol (1991) 1.47
A meta-analysis of trials on aldose reductase inhibitors in diabetic peripheral neuropathy. The Italian Study Group. The St. Vincent Declaration. Diabet Med (1996) 1.46
Aspirin does not interact with ACE inhibitors when both are given early after acute myocardial infarction: results of the GISSI-3 Trial. Heart Dis (2001) 1.45