Published in J Am Chem Soc on July 06, 2005
Human serum albumin inhibits Abeta fibrillization through a "monomer-competitor" mechanism. Biophys J (2009) 1.05
Stoichiometry and affinity of the human serum albumin-Alzheimer's Aβ peptide interactions. Biophys J (2011) 0.99
A new function of human HtrA2 as an amyloid-beta oligomerization inhibitor. J Alzheimers Dis (2009) 0.88
Aβ association inhibition by transferrin. Biophys J (2013) 0.84
Structure based aggregation studies reveal the presence of helix-rich intermediate during α-Synuclein aggregation. Sci Rep (2015) 0.83
Self-assembly of a nine-residue amyloid-forming peptide fragment of SARS corona virus E-protein: mechanism of self aggregation and amyloid-inhibition of hIAPP. Biochemistry (2015) 0.77
Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment. Cell (2009) 4.78
Conformational coupling across the plasma membrane in activation of the EGF receptor. Cell (2013) 2.49
Architecture and membrane interactions of the EGF receptor. Cell (2013) 2.29
Mapping allostery through the covariance analysis of NMR chemical shifts. Proc Natl Acad Sci U S A (2011) 1.89
cAMP activation of PKA defines an ancient signaling mechanism. Proc Natl Acad Sci U S A (2006) 1.79
Dynamically driven ligand selectivity in cyclic nucleotide binding domains. J Biol Chem (2009) 1.38
Signaling through dynamic linkers as revealed by PKA. Proc Natl Acad Sci U S A (2013) 1.28
Regulation of the catalytic activity of the EGF receptor. Curr Opin Struct Biol (2011) 1.26
Understanding the molecular basis for the inhibition of the Alzheimer's Abeta-peptide oligomerization by human serum albumin using saturation transfer difference and off-resonance relaxation NMR spectroscopy. J Am Chem Soc (2007) 1.23
Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1. Elife (2013) 1.22
Entropy-driven cAMP-dependent allosteric control of inhibitory interactions in exchange proteins directly activated by cAMP. J Biol Chem (2008) 1.21
A model for agonism and antagonism in an ancient and ubiquitous cAMP-binding domain. J Biol Chem (2006) 1.16
Mapping allostery through equilibrium perturbation NMR spectroscopy. J Am Chem Soc (2006) 1.10
Definition of an electrostatic relay switch critical for the cAMP-dependent activation of protein kinase A as revealed by the D170A mutant of RIalpha. Proteins (2007) 1.10
The projection analysis of NMR chemical shifts reveals extended EPAC autoinhibition determinants. Biophys J (2012) 1.10
Chemical genomics in Escherichia coli identifies an inhibitor of bacterial lipoprotein targeting. Nat Chem Biol (2009) 1.09
Human serum albumin inhibits Abeta fibrillization through a "monomer-competitor" mechanism. Biophys J (2009) 1.05
Communication between tandem cAMP binding domains in the regulatory subunit of protein kinase A-Ialpha as revealed by domain-silencing mutations. J Biol Chem (2010) 1.05
The auto-inhibitory role of the EPAC hinge helix as mapped by NMR. PLoS One (2012) 1.05
Stoichiometry and affinity of the human serum albumin-Alzheimer's Aβ peptide interactions. Biophys J (2011) 0.99
Induction of flexibility through protein-protein interactions. J Biol Chem (2003) 0.99
Understanding cAMP-dependent allostery by NMR spectroscopy: comparative analysis of the EPAC1 cAMP-binding domain in its apo and cAMP-bound states. J Am Chem Soc (2007) 0.98
Role of dynamics in the autoinhibition and activation of the exchange protein directly activated by cyclic AMP (EPAC). J Biol Chem (2011) 0.93
An apolipoprotein AI mimetic peptide: membrane interactions and the role of cholesterol. Biochemistry (2004) 0.92
A new function of human HtrA2 as an amyloid-beta oligomerization inhibitor. J Alzheimers Dis (2009) 0.88
NMR structures reveal how oxidation inactivates thrombomodulin. Biochemistry (2003) 0.87
Position of residues in transmembrane peptides with respect to the lipid bilayer: a combined lipid Noes and water chemical exchange approach in phospholipid bicelles. J Biomol NMR (2002) 0.87
Analysis and optimization of saturation transfer difference NMR experiments designed to map early self-association events in amyloidogenic peptides. J Phys Chem B (2008) 0.86
Effect of chemical exchange on radiation damping in aqueous solutions of the osmolyte glycine. J Am Chem Soc (2002) 0.86
Using chemical exchange to assign non-covalent protein complexes in slow exchange with the free state: enhanced resolution and efficient signal editing. J Biomol NMR (2004) 0.85
cAMP-dependent allostery and dynamics in Epac: an NMR view. Biochem Soc Trans (2012) 0.85
Aβ association inhibition by transferrin. Biophys J (2013) 0.84
Tapping the translation potential of cAMP signalling: molecular basis for selectivity in cAMP agonism and antagonism as revealed by NMR. Biochem Soc Trans (2014) 0.84
NMR assignment of the cAMP-binding domain A of the PKA regulatory subunit. J Biomol NMR (2006) 0.84
High-resolution protein hydration NMR experiments: probing how protein surfaces interact with water and other non-covalent ligands. Anal Chim Acta (2005) 0.82
In vitro amyloid-β binding and inhibition of amyloid-β self-association by therapeutic albumin. J Alzheimers Dis (2014) 0.82
Mapping the interactions between the Alzheimer's Aβ-peptide and human serum albumin beyond domain resolution. Biophys J (2013) 0.82
Analysis and parametric optimization of 1H off-resonance relaxation NMR experiments designed to map polypeptide self-recognition and other noncovalent interactions. J Phys Chem B (2006) 0.81
Allosteric linkers in cAMP signalling. Biochem Soc Trans (2014) 0.81
The kinase domain of Drosophila Tribbles is required for turnover of fly C/EBP during cell migration. Dev Biol (2013) 0.81
Dynamics of the fragment of thrombomodulin containing the fourth and fifth epidermal growth factor-like domains correlate with function. Biochemistry (2005) 0.80
Dynamic unfolding of a regulatory subunit of cAMP-dependent protein kinase by capillary electrophoresis: Impact of cAMP dissociation on protein stability. Electrophoresis (2006) 0.78
A novel non-canonical forkhead-associated (FHA) domain-binding interface mediates the interaction between Rad53 and Dbf4 proteins. J Biol Chem (2013) 0.77
Ultrasonic and densimetric characterization of the association of cyclic AMP with the cAMP-binding domain of the exchange protein EPAC1. J Phys Chem B (2013) 0.77
Structural Basis of Tonic Inhibition by Dimers of Dimers in Hyperpolarization-Activated Cyclic-Nucleotide-Modulated (HCN) Ion Channels. J Phys Chem B (2016) 0.76
Degradation of MAC13243 and studies of the interaction of resulting thiourea compounds with the lipoprotein targeting chaperone LolA. Bioorg Med Chem Lett (2013) 0.76
Label-free assay for thermodynamic analysis of protein-ligand interactions: a multivariate strategy for allosteric ligand screening. Biochemistry (2009) 0.76